RegulonDB RegulonDB 11.2: Gene Form
   

tnaB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

tnaA tnaB mdtL yidZ

Gene      
Name: tnaB    Texpresso search in the literature
Synonym(s): ECK3702, EG11006, b3709, tnaP, trpP
Genome position(nucleotides): 3890236 --> 3891483
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 46.47
External database links:  
ASAP:
 ABE-0012135
CGSC:
 69
ECHOBASE:
 EB0999
ECOLIHUB:
 tnaB
OU-MICROARRAY:
 b3709
STRING:
 511145.b3709
COLOMBOS: tnaB


Product      
Name: tryptophan:H+ symporter TnaB
Synonym(s): TnaB, TnaB tryptophan ArAAP transporter, TnaP, TrpP
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 45.211
Isoelectric point: 9.253
Motif(s):
 
Type Positions Sequence Comment
3 -> 3 D UniProt: In Ref. 5; AAA24677..
7 -> 403 KKHSAFWGVMVIAGTVIGGGMFALPVDLAGAWFFWGAFILIIAWFSMLHSGLLLLEANLNYPVGSSFNTITKDLIGNTWNIISGITVAFVLYILTYAYISANGAIISETISMNLGYHANPRIVGICTAIFVASVLWLSSLAASRITSLFLGLKIISFVIVFGSFFFQVDYSILRDATSSTAGTSYFPYIFMALPVCLASFGFHGNIPSLIICYGKRKDKLIKSVVFGSLLALVIYLFWLYCTMGNIPRESFKAIISSGGNVDSLVKSFLGTKQHGIIEFCLLVFSNLAVASSFFGVTLGLFDYLADLFKIDNSHGGRFKTVLLTFLPPALLYLIFPNGFIYGIGGAGLCATIWAVIIPAVLAIKARKKFPNQMFTVWGGNLIPAIVILFGITVILCW
12 -> 32 FWGVMVIAGTVIGGGMFALPV UniProt: Helical.
34 -> 54 LAGAWFFWGAFILIIAWFSML UniProt: Helical.
87 -> 107 IISGITVAFVLYILTYAYISA UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.15 - tryptophan
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015293 - symporter activity
GO:0015173 - aromatic amino acid transmembrane transporter activity
biological_process GO:0006865 - amino acid transport
GO:0006569 - tryptophan catabolic process
GO:0015801 - aromatic amino acid transport
GO:0003333 - amino acid transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P23173
ECOCYC:
 TNAB-MONOMER
ECOLIWIKI:
 b3709
INTERPRO:
 IPR018227
INTERPRO:
 IPR013059
INTERPRO:
 IPR013061
PANTHER:
 PTHR46997
PFAM:
 PF03222
PRIDE:
 P23173
PRINTS:
 PR00166
PRODB:
 PRO_000024076
PROSITE:
 PS00594
REFSEQ:
 NP_418165
SMR:
 P23173
UNIPROT:
 P23173


Operon      
Name: tnaCAB         
Operon arrangement:
Transcription unit        Promoter
tnaC
tnaCAB
tnaAB


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, TorR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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