RegulonDB

Gene
Name:	yaiW
Synonym(s):	ECK0373, G6227, b0378
Genome position(nucleotides):	397872 --> 398966
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	53.42
External database links:

ASAP:	ABE-0001299
ECHOBASE:	EB3375
ECOLIHUB:	yaiW
OU-MICROARRAY:	b0378
STRING:	511145.b0378
COLOMBOS:	yaiW

Product

Name:

surface-exposed outer membrane lipoprotein

Synonym(s):

YaiW

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol,outer membrane

Molecular weight:

40.414

Isoelectric point:

10.101

Motif(s):

Type	Positions	Sequence	Comment
	50 -> 363	VKDRDAWAKDLATTFESQGLAPTLENVCSVLAVAQQESNYQADPAVPGLSKIAWQEIDRRAERMHIPAFLVHTALKIKSPNGKSYSERLDSVRTEKQLSAIFDDLINMVPMGQTLFGSLNPVRTGGPMQVSIAFAEQHTKGYPWKMDGTVRQEVFSRRGGLWFGTYHLLNYPASYSAPIYRFADFNAGWYASRNAAFQNAVSKASGVKLALDGDLIRYDSKEPGKTELATRKLAAKLGMSDSEIRRQLEKGDSFSFEETALYKKVYQLAETKTGKSLPREMLPGIQLESPKITRNLTTAWFAKRVDERRARCMK

Classification:

Multifun Terms (GenProtEC)
		2 - information transfer --> 2.2 - RNA related --> 2.2.2 - Transcription related
		3 - regulation --> 3.1 - type of regulation --> 3.1.2 - transcriptional level
		6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)
	cellular_component	GO:0005829 - cytosol GO:0031240 - external side of cell outer membrane
	biological_process	GO:0006351 - transcription, DNA-templated GO:1901652 - response to peptide

Note(s):

Note(s): ...[more].

Evidence:

[COMP-AINF-FN-FROM-SEQ] Automated inference of function from sequence
[COMP-HINF-FN-FROM-SEQ] Human inference of function from sequence
[EXP-IDA-UNPURIFIED-PROTEIN-NH] Assay of unpurified protein expressed in its native host

Reference(s):

[1] Arnold MF., et al., 2014
[2] Perez-Rueda E., et al., 2000
[3] Perez-Rueda E., et al., 2004

External database links:

ALPHAFOLD:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

PFAM:

PRIDE:

REFSEQ:

SMR:

UNIPROT:

Operon

Name:

sbmA-yaiW

Operon arrangement:

Transcription unit	Promoter
sbmA-yaiW	sbmAp

Transcriptional Regulation
	Display Regulation
Activated by:	CpxR

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References

Reference(s)
[1] Arnold MF., Caro-Hernandez P., Tan K., Runti G., Wehmeier S., Scocchi M., Doerrler WT., Walker GC., Ferguson GP., 2014, Enteric YaiW is a surface-exposed outer membrane lipoprotein that affects sensitivity to an antimicrobial peptide., J Bacteriol 196(2):436-44
[2] Perez-Rueda E., Collado-Vides J., 2000, The repertoire of DNA-binding transcriptional regulators in Escherichia coli K-12., Nucleic Acids Res 28(8):1838-47
[3] Perez-Rueda E., Collado-Vides J., Segovia L., 2004, Phylogenetic distribution of DNA-binding transcription factors in bacteria and archaea., Comput Biol Chem 28(5-6):341-50