RegulonDB RegulonDB 11.2: Gene Form
   

gspB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

gspA gspB rpsJ DksA-ppGpp DksA-ppGpp TSS_3833 TSS_3833 rpsJp rpsJp TSS_3832 TSS_3832 TSS_3831 TSS_3831 TSS_3830 TSS_3830 TSS_3829 TSS_3829 TSS_3828 TSS_3828 TSS_3827 TSS_3827 TSS_3826 TSS_3826 TSS_3825 (cluster) TSS_3825 (cluster) TSS_3824 (cluster) TSS_3824 (cluster) TSS_3823 (cluster) TSS_3823 (cluster) TSS_3822 TSS_3822 TSS_3821 TSS_3821 TSS_3820 (cluster) TSS_3820 (cluster) TSS_3819 TSS_3819

Gene      
Name: gspB    Texpresso search in the literature
Synonym(s): ECK3309, EG11263, b3322, pinO, pioO
Genome position(nucleotides): 3453508 <-- 3453927
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 45.95
External database links:  
ASAP:
 ABE-0010865
ECHOBASE:
 EB1243
ECOLIHUB:
 gspB
OU-MICROARRAY:
 b3322
STRING:
 511145.b3322
COLOMBOS: gspB


Product      
Name: putative general secretion pathway protein B
Synonym(s): GspB, PinO, PioO, calcium-binding protein required for initiation of chromosome replication
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane,cytosol
Molecular weight: 15.876
Isoelectric point: 4.469
Motif(s):
 
Type Positions Sequence Comment
1 -> 66 MFEFYIAAREQKETGHPGIFSRQKHSTIIYVICLLLICLWFAGMVLVGGYARQLWVLWIVKAEVTV UniProt: In Ref. 1; V00344..
28 -> 48 IIYVICLLLICLWFAGMVLVG UniProt: Helical.
93 -> 139 VEEEDDPGVAVENAPSSSEDEENTVEESEEKAGLRERVKNALNELER UniProt: Disordered; Sequence Annotation Type: region of interest.
120 -> 139 SEEKAGLRERVKNALNELER UniProt: Basic and acidic residues; Sequence Annotation Type: compositionally biased region.

 
Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
Note(s): Note(s): ...[more].
Reference(s): [1] Guzman EC., et al., 1991
External database links:  
ALPHAFOLD:
 P03825
ECOCYC:
 EG11263-MONOMER
ECOLIWIKI:
 b3322
PRIDE:
 P03825
PRODB:
 PRO_000023553
REFSEQ:
 NP_417781
UNIPROT:
 P03825


Operon      
Name: gspAB         
Operon arrangement:
Transcription unit        Promoter
gspAB
gspAB
gspAB
gspAB


Transcriptional Regulation      
Display Regulation             
Repressed by: H-NS


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3819 3453214 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3820 (cluster) 3453225 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3821 3453229 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3822 3453234 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3823 (cluster) 3453240 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3824 (cluster) 3453244 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3825 (cluster) 3453252 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3826 3453255 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3827 3453263 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3828 3453271 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3829 3453287 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3830 3453290 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3831 3453439 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3832 3453441 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_3833 3453450 reverse nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Guzman EC., Jimenez-Sanchez A., 1991, Location of pinO, a new gene located between tufA and rpsJ, on the physical map of the Escherichia coli chromosome., J Bacteriol 173(23):7409

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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