RegulonDB RegulonDB 11.2: Gene Form
   

yhhQ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yhhQ dcrB tusA anti-terminator terminator terminator dcrBp6 dcrBp6 TSS_4076 TSS_4076 dcrBp8 dcrBp8 dcrBp2 dcrBp2 dcrBp1 dcrBp1 yhhQp5 yhhQp5 tusAp7 tusAp7

Gene      
Name: yhhQ    Texpresso search in the literature
Synonym(s): ECK3455, EG12217, b3471
Genome position(nucleotides): 3609217 --> 3609882
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 50.75
External database links:  
ASAP:
 ABE-0011340
ECHOBASE:
 EB2131
ECOLIHUB:
 yhhQ
OU-MICROARRAY:
 b3471
STRING:
 511145.b3471
COLOMBOS: yhhQ


Product      
Name: queuosine precursor transporter
Synonym(s): YhhQ
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 25.269
Isoelectric point: 10.072
Motif(s):
 
Type Positions Sequence Comment
13 -> 33 LFWLSLFHLLVITSSNYLVQL UniProt: Helical.
35 -> 55 VSILGFHTTWGAFSFPFIFLA UniProt: Helical.
43 -> 198 TWGAFSFPFIFLATDLTVRIFGAPLARRIIFAVMIPALLISYVISSLFYMGSWQGFGALAHFNLFVARIATASFMAYALGQILDVHVFNRLRQSRRWWLAPTASTLFGNVSDTLAFFFIAFWRSPDAFMAEHWMEIALVDYCFKVLISIVFFLPMY
71 -> 91 IIFAVMIPALLISYVISSLFY UniProt: Helical.
98 -> 118 FGALAHFNLFVARIATASFMA UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0022857 - transmembrane transporter activity
biological_process GO:1990397 - queuosine salvage
GO:0055085 - transmembrane transport
GO:0072531 - pyrimidine-containing compound transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P37619
ECOCYC:
 EG12217-MONOMER
ECOLIWIKI:
 b3471
INTERPRO:
 IPR003744
PANTHER:
 PTHR34300
PFAM:
 PF02592
PRIDE:
 P37619
REFSEQ:
 NP_417928
UNIPROT:
 P37619


Operon      
Name: yhhQ         
Operon arrangement:
Transcription unit        Promoter
yhhQ


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter tusAp7 3609020 reverse nd [COMP-AINF] [1]
  promoter yhhQp5 3609119 forward nd [COMP-AINF] [1]
  promoter dcrBp1 3609767 forward nd [COMP-AINF] [1]
  promoter dcrBp2 3609780 forward nd [COMP-AINF] [1]
  promoter dcrBp8 3609913 forward nd [COMP-AINF] [1]
  promoter TSS_4076 3609917 forward nd [RS-EPT-CBR] [2]
  promoter dcrBp6 3609930 forward nd [COMP-AINF] [1]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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