# Copies and Copyright-Notice # # RegulonDB is free for academic/noncommercial use # # User is not entitled to change or erase data sets of the RegulonDB # database or to eliminate copyright notices from RegulonDB. Furthermore, # User is not entitled to expand RegulonDB or to integrate RegulonDB partly # or as a whole into other databank systems, without prior written consent # from CCG-UNAM. # # Please check the license at http://regulondb.ccg.unam.mx/menu/download/full_version/terms_and_conditions.jsp # # Citation # # Tierrafría, V. H. et al. (2022). RegulonDB 11.0: Comprehensive high-throughput datasets on transcriptional regulation in Escherichia coli K-12, # Microb Genom. 2022 May;8(5). doi: 10.1099/mgen.0.000833. PMID: 35584008. https://doi.org/10.1099/mgen.0.000833 # # # Contact # # Person: RegulonDB Team # Web Page: http://regulondb.ccg.unam.mx/menu/about_regulondb/contact_us/index.jsp # (regulondb@ccg.unam.mx) # # # Release: 11.2 Date: 05/22/2023 # Genome version: U00096.3, Refseq version: NC_000913.3; GI:556503834 # ___________________________________________________________________________ # Created: 06/12/2023 13:38:20 # Columns: # (1) Gene identifier assigned by RegulonDB # (2) Gene name # (3) Blattner number (bnumber) of the gene # (4) Gene left end position in the genome # (5) Gene right end position in the genome # (6) DNA strand where the gene is coded # (7) Product name of the gene # (8) Evidence that supports the existence of the gene # (9) PMIDs list # (10) Evidence confidence level (Confirmed, Strong, Weak) # (11) All bnumber related to gene # (12) Other database's id related to gene ECK120001251 thrL b0001 190 255 forward operon leader peptide [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 3112412,318654,6811557, Weak b0001 ECK120000987 thrA b0002 337 2799 forward fused aspartate kinase/homoserine dehydrogenase 1 b0002 ECK120000988 thrB b0003 2801 3733 forward homoserine kinase b0003 ECK120000989 thrC b0004 3734 5020 forward threonine synthase b0004 ECK120002701 yaaX b0005 5234 5530 forward DUF2502 domain-containing protein YaaX 24391520, b0005 ECK120000009 yaaA b0006 5683 6459 reverse DNA binding and peroxide stress response protein YaaA [EXP-IMP|W|Inferred from mutant phenotype] 21378183,24952731, Weak b0006 ECK120001508 yaaJ b0007 6529 7959 reverse putative transporter YaaJ [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 16397293,31438868,32518189, Weak b0007 ECK120001509 talB b0008 8238 9191 forward transaldolase B 18175070,21290439, b0008 ECK120001467 mog b0009 9306 9893 forward molybdopterin adenylyltransferase b0009 ECK120001468 satP b0010 9928 10494 reverse acetate/succinate:H symporter b0010 ECK120002702 yaaW b0011 10643 11356 reverse putative enzyme-specific chaperone YaaW 17636861, b0011 ECK120001465 mbiA b0012 10830 11315 forward uncharacterized protein MbiA b0012 ECK120004453 yaaI b0013 11382 11786 reverse DUF2541 domain-containing protein YaaI 24391520, b0013 ECK120000235 dnaK b0014 12163 14079 forward chaperone protein DnaK [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 10024459,11544208,12741845,1361234,1386674,19439666,21221969,21474779,2249663,24280225,25451597,26836408,27075190,27189986,28577028,2905317,29643454,29669923,29812913,30271935,30442809,31524873,31806707,328896,33310019,33937334,34578514,34625496,34735438,360041,384143,7037741,7932696,8530409,8626401,9822822, Weak b0014 ECK120002604 tpke11 14080 14167 forward ECK120000234 dnaJ b0015 14168 15298 forward chaperone protein DnaJ 3003084,360036,360041, b0015 ECK120002703 insL1 b0016 15445 16557 forward IS186/IS421 transposase b0016 ECK120002704 Phantom Gene b0017 15869 16177 reverse b0017 ECK120002652 hokC b4412 16751 16903 reverse protein HokC b4412 ECK120000366 mokC b0018 16751 16960 reverse regulatory protein MokC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10361310, Weak b0018 ECK120002653 sokC b4413 16952 17010 forward small regulatory RNA antitoxin SokC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 10361310,1943701, Weak b4413 ECK120000645 nhaA b0019 17489 18655 forward Na antiporter NhaA 10398838,10671505,11275556,11697236,11779554,15236973,15282168,15642346,15894644,15962009,16139785,16298390,16477015,16919297,16935297,18083192,18387952,18930435,19274728,21566125,22431724,23131124,23360655,23733686,23959879,25950963,26392528,26417087,27708266,30310075,33257549,34273399,7774707,7929345,8017942,8588889,9312050,9853399,9877164, b0019 ECK120001066 nhaR b0020 18715 19620 forward DNA-binding transcriptional activator NhaR 1316901,1630901,2429258,3413113,8168494, b0020 ECK120023911 insAB1 19811 20508 reverse InsAB' transposase [EXP-IMP|W|Inferred from mutant phenotype] 8083181, Weak ECK120002705 insB1 b0021 19811 20314 reverse IS1 protein InsB b0021 ECK120002706 insA1 b0022 20233 20508 reverse IS1 protein InsA [EXP-IMP|W|Inferred from mutant phenotype] 8083181, Weak b0022 ECK120000910 rpsT b0023 20815 21078 reverse 30S ribosomal subunit protein S20 1091486,4606155, b0023 ECK120002707 yaaY b0024 21181 21399 forward DUF2575 domain-containing protein YaaY b0024 ECK120001067 ribF b0025 21407 22348 forward bifunctional riboflavin kinase / FMN adenylyltransferase b0025 ECK120000485 ileS b0026 22391 25207 forward isoleucine—tRNA ligase 1329109,26070674,5324173,6390679,7629064, b0026 ECK120000541 lspA b0027 25207 25701 forward lipoprotein signal peptidase 1544479,2993296,3112119,3282924,6186482,6313636,6347715,6350278,6754699,7048314,7050113,8051048,8407783, b0027 ECK120001068 fkpB b0028 25826 26275 forward peptidyl-prolyl isomerase FkpB 22952665,26070674, b0028 ECK120001069 ispH b0029 26277 27227 forward 4-hydroxy-3-methylbut-2-enyl diphosphate reductase b0029 ECK120001070 rihC b0030 27293 28207 forward ribonucleoside hydrolase RihC b0030 ECK120000200 dapB b0031 28374 29195 forward 4-hydroxy-tetrahydrodipicolinate reductase 10368155,17870049,26815040,6110161,6251070,8152, b0031 ECK120000130 carA b0032 29651 30799 forward carbamoyl-phosphate synthetase small subunit 24516157,6330744,84616, b0032 ECK120000131 carB b0033 30817 34038 forward carbamoyl-phosphate synthetase large subunit 6308632, b0033 ECK120002708 caiF b0034 34300 34695 forward DNA-binding transcriptional activator CaiF 10564497,8631699,9573142, b0034 ECK120002330 caiE b0035 34781 35371 reverse putative transferase CaiE b0035 ECK120001510 caiD b0036 35377 36162 reverse crotonobetainyl-CoA hydratase b0036 ECK120001511 caiC b0037 36271 37824 reverse carnitine—CoA ligase b0037 ECK120001512 caiB b0038 37898 39115 reverse γ-butyrobetainyl-CoA:carnitine CoA transferase b0038 ECK120001513 caiA b0039 39244 40386 reverse crotonobetainyl-CoA reductase 11551212,23718679, b0039 ECK120001514 caiT b0040 40417 41931 reverse L-carnitine:γ-butyrobetaine antiporter b0040 ECK120001515 fixA b0041 42403 43173 forward putative electron transfer flavoprotein FixA [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 12081978,7473063,7815937, Weak b0041 ECK120001516 fixB b0042 43188 44129 forward putative electron transfer flavoprotein FixB [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 12081978,7473063, Weak b0042 ECK120001517 fixC b0043 44180 45466 forward putative oxidoreductase FixC b0043 ECK120001518 fixX b0044 45463 45750 forward putative ferredoxin FixX b0044 ECK120001519 yaaU b0045 45807 47138 forward putative transporter YaaU 31438868, b0045 ECK120001520 kefF b0046 47246 47776 forward regulator of KefC-mediated potassium transport and quinone oxidoreductase b0046 ECK120000514 kefC b0047 47769 49631 forward K antiporter KefC b0047 ECK120000320 folA b0048 49823 50302 forward dihydrofolate reductase 29301959, b0048 ECK120000044 apaH b0049 50380 51222 reverse diadenosine tetraphosphatase 2159411,2172926,2554885,2670894,27718375,2820468,3031429,8119291,9286857, b0049 ECK120000043 apaG b0050 51229 51606 reverse DUF525 domain-containing protein ApaG b0050 ECK120000516 rsmA b0051 51609 52430 reverse 16S rRNA mA1519 dimethyltransferase 12432951,19520088,22391551,23095113,2670894,3122846,34086932,3905517,4329247,4336392,4570603,6256606,6450312, b0051 ECK120000684 pdxA b0052 52427 53416 reverse 4-hydroxythreonine-4-phosphate dehydrogenase b0052 ECK120000974 surA b0053 53416 54702 reverse chaperone SurA 10500101,10748200,11274153,11844765,12003929,14594826,15489426,15603590,16102012,16199663,21671888,23275244,23871892,24586054,27482090,28919234,30684235,32602996,32748422,32786408,7878731,7889934,9335308, b0053 ECK120001521 lptD b0054 54755 57109 reverse lipopolysaccharide assembly protein LptD [EXP-IMP|W|Inferred from mutant phenotype] 12207697,27439868,29802191,34070637, Weak b0054 ECK120001522 djlA b0055 57364 58179 forward co-chaperone protein DjlA [EXP|W|Inferred from experiment] 11106641,33310019, Weak b0055 ECK120002332 yabP b0056 58474 59124 forward putative uncharacterized protein YabP b0056,b4659 ECK120002333 yabQ b0057 59121 59279 forward protein YabQ b0057,b4659 ECK120002331 rluA b0058 59687 60346 reverse 23S rRNA pseudouridine synthase 21142053,27292228, b0058 ECK120001071 rapA b0059 60358 63264 reverse RNA polymerase-binding ATPase and RNAP recycling factor [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 11751638,11772406,11890942,14712653,16223443,17913745,21533049,8464078,9507009,9614128, Weak b0059 ECK120000738 polB b0060 63429 65780 reverse DNA polymerase II 17586534,1911943,20064374,20523737,2217198,26657641,326258,4559593,4564210,4595569,4604726,4605284,4943843,8594343,9079692, b0060 ECK120000051 araD b0061 65855 66550 reverse L-ribulose-5-phosphate 4-epimerase AraD b0061 ECK120000048 araA b0062 66835 68337 reverse L-arabinose isomerase b0062 ECK120000049 araB b0063 68348 70048 reverse ribulokinase b0063 ECK120000050 araC b0064 70387 71265 forward DNA-binding transcriptional dual regulator AraC 2231717,7768852, b0064 ECK120001523 yabI b0065 71351 72115 forward DedA family protein YabI [EXP-IGI|W|Inferred from genetic interaction] 18456815, Weak b0065 ECK120001524 thiQ b0066 72229 72927 reverse thiamine ABC transporter ATP binding subunit b0066 ECK120001525 thiP b0067 72911 74521 reverse thiamine ABC transporter membrane subunit b0067 ECK120001526 thiB b0068 74497 75480 reverse thiamine ABC transporter periplasmic binding protein 12376536,28520932,4573077,4586830,4945201, b0068 ECK120002641 sroA b4762 75516 75608 reverse small RNA SroA 12376536,28071751,28520932, b4762 ECK120001999 sgrR b0069 75644 77299 reverse DNA-binding transcriptional dual regulator SgrR [EXP-IMP|W|Inferred from mutant phenotype] 15522088, Weak b0069 ECK120002667 sgrS b4577 77367 77593 forward small regulatory RNA SgrS [EXP|W|Inferred from experiment],[EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 15522088,15650111,23873911,25582129,28119418,28289085,29137641,30287822,30700509,32291821,33425989, Weak b4577 ECK120033551 sgrT b4662 77388 77519 forward PtsG glucose transporter inhibitor [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IPI|W|Inferred from physical interaction] 18042713,24957761,29111488, Weak b4662 ECK120001692 setA b0070 77621 78799 forward sugar exporter SetA b0070 ECK120001527 leuD b0071 78848 79453 reverse 3-isopropylmalate dehydratase subunit LeuD b0071 ECK120001528 leuC b0072 79464 80864 reverse 3-isopropylmalate dehydratase subunit LeuC 15657047,28637476,28744578,320178, b0072 ECK120001529 leuB b0073 80867 81958 reverse 3-isopropylmalate dehydrogenase b0073 ECK120001204 leuA b0074 81958 83529 reverse 2-isopropylmalate synthase 11056062,12486047,14017963,1630901,17463081,21601099,29240717,320178,32876943,9279396, b0074 ECK120001253 leuL b0075 83622 83708 reverse operon leader peptide [AS-HYPO|W|Author hypothesis] 6171647, Weak b0075 ECK120000524 leuO b0076 84368 85312 forward DNA-binding transcriptional dual regulator LeuO [EXP|W|Inferred from experiment],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 11121424,15582999,16207917,1630901,3413113,3519576,7836317,9422614, Weak b0076 ECK125276528 yabR b4726 85467 85511 reverse protein YabR b4726 ECK120000493 ilvI b0077 85630 87354 forward acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit 3891724, b0077 ECK120000492 ilvH b0078 87357 87848 forward acetolactate synthase / acetohydroxybutanoate synthase, regulatory subunit b0078 ECK120001247 fruL b0079 87860 87946 forward b0079 ECK120000332 cra b0080 88028 89032 forward DNA-binding transcriptional dual regulator Cra 1630901,1851954,2198273,8230205,9371462, b0080 ECK120001072 mraZ b0081 89634 90092 forward DNA-binding transcriptional repressor MraZ [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[EXP-IPI|W|Inferred from physical interaction],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 24659771, Strong b0081 ECK120001073 rsmH b0082 90094 91035 forward 16S rRNA mC1402 methyltransferase b0082 ECK120001074 ftsL b0083 91032 91397 forward cell division protein FtsL [EXP-IMP|W|Inferred from mutant phenotype] 1332942,34070637, Weak b0083 ECK120000335 ftsI b0084 91413 93179 forward peptidoglycan DD-transpeptidase FtsI 14663069,15516588,20079830,28553265,30056491,30622193,34223033,6450748,7030331, b0084 ECK125302576 ftsO b4810 92485 92658 forward small regulatory RNA FtsO [EXP-IMP|W|Inferred from mutant phenotype] 33460557, Weak b4810 ECK120000614 murE b0085 93166 94653 forward UDP--acetylmuramoyl-L-alanyl-D-glutamate—2,6-diaminopimelate ligase 2198024,2692800,2841306, b0085 ECK120000615 murF b0086 94650 96008 forward D-alanyl-D-alanine-adding enzyme 17216029,19229285,2841306,31743648,4563986, b0086 ECK120000597 mraY b0087 96002 97084 forward phospho--acetylmuramoyl-pentapeptide-transferase b0087 ECK120000613 murD b0088 97087 98403 forward UDP--acetylmuramoyl-L-alanine—D-glutamate ligase b0088 ECK120000338 ftsW b0089 98403 99647 forward peptidoglycan glycosyltransferase FtsW 2509435,26335199,30112777,33857142, b0089 ECK120000616 murG b0090 99644 100711 forward N-acetylglucosaminyl transferase 10338150,10790316,11181358,11720853,11846551,12022887,12069409,12654311,12758253,12813070,12851929,15157881,15793120,17692452,2187180,2197603,2681153,6998962,9721276, b0090 ECK120000612 murC b0091 100765 102240 forward UDP--acetylmuramate—L-alanine ligase b0091 ECK120000208 ddlB b0092 102233 103153 forward D-alanine—D-alanine ligase B 16158456,17267218,18774266,19053785,19196510,19229285,21827632,21831641,22876277,29208891,32094588,4567144, b0092 ECK120000336 ftsQ b0093 103155 103985 forward cell division protein FtsQ [EXP-IMP|W|Inferred from mutant phenotype] 34070637,6998961, Weak b0093 ECK120000333 ftsA b0094 103982 105244 forward cell division protein FtsA [EXP-IMP|W|Inferred from mutant phenotype] 19415799,21257762,22111832,22328664,25213228,25496160,25496259,27503875,29967164,31175681,31893220,32636250,34453005,4583216,8509333,9882665, Weak b0094 ECK120000341 ftsZ b0095 105305 106456 forward cell division protein FtsZ [EXP-IMP|W|Inferred from mutant phenotype] 2045370,2895672,30056491,30523075,30742332,31893220,32424210, Weak b0095 ECK120000259 lpxC b0096 106557 107474 forward UDP-3--acetylglucosamine deacetylase 21193611,23091052, b0096 ECK120001075 secM b0097 107705 108217 forward SecA translation regulator [EXP|W|Inferred from experiment] 10986266,11477104,11574054,1833384,2146254,21464303,2536662, Weak b0097 ECK120000925 secA b0098 108279 110984 forward protein translocation ATPase 2841285, b0098 ECK120000619 mutT b0099 111044 111433 forward 8-oxo-dGTP diphosphatase 11856756,30087411, b0099 ECK120002709 b0100 b0100 111564 111698 reverse ECK120002191 yacG b0101 111649 111846 reverse DNA gyrase inhibitor YacG [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 18586829, Weak b0101 ECK120002190 zapD b0102 111856 112599 reverse cell division factor ZapD b0102 ECK120002189 coaE b0103 112599 113219 reverse dephospho-CoA kinase b0103 ECK125276507 yacM b4727 113244 113288 forward protein YacM b4727 ECK120000415 guaC b0104 113444 114487 forward GMP reductase b0104 ECK120002710 b0105 b0105 114407 114514 reverse ECK120001732 hofC b0106 114522 115724 reverse inner membrane protein HofC b0106 ECK120002011 hofB b0107 115714 117099 reverse T2SSE family protein b0107 ECK120002012 ppdD b0108 117109 117549 reverse prepilin-type N-terminal cleavage/methylation domain-containing protein PpdD 10811613,23006128, b0108 ECK120001500 nadC b0109 117752 118645 reverse quinolinate phosphoribosyltransferase (decarboxylating) b0109 ECK120000037 ampD b0110 118733 119284 forward 1,6-anhydro--acetylmuramoyl-L-alanine amidase 19648247,1987637,9411793, b0110 ECK120000038 ampE b0111 119281 120135 forward protein AmpE b0111 ECK120000080 aroP b0112 120178 121551 reverse aromatic amino acid:H symporter AroP b0112 ECK120001076 pdhR b0113 122092 122856 forward DNA-binding transcriptional dual regulator PdhR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis],[EXP-IDA-PART-PURIFIED-PROTEIN|W|Assay of partially-purified protein ] 17513468,2060763,7783622,8057842,8262214, Weak b0113 ECK120002605 tp2 122697 122857 reverse ECK120000021 aceE b0114 123017 125680 forward pyruvate dehydrogenase E1 component 2655695,6343085, b0114 ECK120000022 aceF b0115 125695 127587 forward pyruvate dehydrogenase, E2 subunit 12501174,12651118,1696836,3087386,3101735,327021,3297160,3902834,3903169,6308128,6344073,6803765,6998493, b0115 ECK120000536 lpd b0116 127912 129336 forward lipoamide dehydrogenase b0116 ECK120002192 yacH b0117 129407 131260 reverse DUF3300 domain-containing protein YacH b0117 ECK120002193 acnB b0118 131615 134212 forward AcnB 17384228,19383690,21972224,22198407, b0118 ECK120002328 yacL b0119 134388 134750 forward PF06062 family protein YacL b0119 ECK120000951 speD b0120 134788 135582 reverse -adenosylmethionine decarboxylase proenzyme 159306,1872800,2666401,3076346,3091070,3514574,3902085,6351843,6353153,6353154,7009611,7752200,8081865, b0120 ECK120000952 speE b0121 135598 136464 reverse spermidine synthase b0121 ECK120001077 yacC b0122 136570 136917 reverse putative lipoprotein YacC b0122 ECK120002194 cueO b0123 137083 138633 forward multicopper oxidase CueO 12099683,12142427,16828082,17215254,17217912,19297322,20727354,21142169,22564733,23337502,23933321,27710945,28473295,30770473,31586033,33332702, b0123 ECK120000362 gcd b0124 138835 141225 reverse quinoprotein glucose dehydrogenase 8419307,8554505, b0124 ECK120002443 hpt b0125 141431 141967 forward hypoxanthine phosphoribosyltransferase b0125 ECK120002195 can b0126 142008 142670 reverse carbonic anhydrase 2 32576029,8673298, b0126 ECK120002196 yadG b0127 142779 143705 forward putative ABC transporter ATP-binding protein YadG 31438868, b0127 ECK120002197 yadH b0128 143702 144472 forward putative ABC transporter membrane subunit YadH 29176613, b0128 ECK120002198 yadI b0129 144577 145017 forward putative PTS enzyme IIA component YadI 31438868, b0129 ECK120001687 yadE b0130 145081 146310 forward putative polysaccharide deacetylase lipoprotein YadE 24391520, b0130 ECK120001685 panD b0131 146314 146694 reverse aspartate 1-decarboxylase proenzyme b0131 ECK120001686 rpnC b0132 146968 147870 forward recombination-promoting nuclease RpnC [EXP-IMP|W|Inferred from mutant phenotype] 28096446,30904393, Weak b0132 ECK120001684 panC b0133 147944 148795 reverse pantothenate synthetase 12748954,16705359,23550886, b0133 ECK120001618 panB b0134 148807 149601 reverse 3-methyl-2-oxobutanoate hydroxymethyltransferase 12773157,2995306,8837478, b0134 ECK120001621 yadC b0135 149715 150953 reverse fimbrial tip-adhesin YadC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825,27696649, Weak b0135 ECK120002200 yadK b0136 151003 151599 reverse putative fimbrial protein YadK [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825,27696649, Weak b0136 ECK120002201 yadL b0137 151626 152231 reverse putative fimbrial protein YadL 21344461,23382825, b0137 ECK120002202 yadM b0138 152243 152812 reverse putative fimbrial protein YadM [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825,27696649, Weak b0138 ECK120001897 htrE b0139 152829 155426 reverse putative fimbrial usher protein HtrE [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825,27696649,8102362, Weak b0139 ECK120001898 yadV b0140 155461 156201 reverse putative fimbrial chaperone YadV [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 21344461,23382825,27696649,8102362, Weak b0140 ECK120002203 yadN b0141 156299 156883 reverse putative fimbrial protein YadN [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825,27696649, Weak b0141 ECK120001342 folK b0142 157253 157732 reverse 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase b0142 ECK120000683 pcnB b0143 157729 159126 reverse poly(A) polymerase I 17179213,18682528,28426097, b0143 ECK120001331 gluQ b0144 159186 160112 reverse glutamyl-Q tRNA synthetase b0144 ECK120000224 dksA b0145 160149 160604 reverse RNA polymerase-binding transcription factor DksA [EXP-IMP|W|Inferred from mutant phenotype] 12142416, Weak b0145 ECK120000938 sfsA b0146 160782 161486 reverse sugar fermentation stimulation protein A [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 15556475,2013578, Weak b0146 ECK120002205 thpR b0147 161501 162031 reverse RNA 2',3'-cyclic phosphodiesterase b0147 ECK120002204 hrpB b0148 162105 164534 forward RNA-dependent NTPase HrpB b0148 ECK120000598 mrcB b0149 164730 167264 forward PBP1Bγ 3898066, b0149 ECK120000598 mrcB b0149 164730 167264 forward peptidoglycan glycosyltransferase / peptidoglycan DD-transpeptidase MrcB 3898066, b0149 ECK120000296 fhuA b0150 167484 169727 forward ferrichrome outer membrane transporter/phage receptor [EXP-IMP|W|Inferred from mutant phenotype] 12383253,12558182,30271910,32241226, Weak b0150 ECK120000298 fhuC b0151 169778 170575 forward iron(III) hydroxamate ABC transporter ATP binding subunit b0151 ECK120000299 fhuD b0152 170575 171465 forward iron(III) hydroxamate ABC transporter periplasmic binding protein 16158230,1830209,21194366,2254301,7651325, b0152 ECK120000297 fhuB b0153 171462 173444 forward iron(III) hydroxamate ABC transporter membrane subunit 8861219, b0153 ECK120000425 hemL b0154 173602 174882 reverse glutamate-1-semialdehyde 2,1-aminomutase 1427085,15126461,1900346,21620993,2511063,25716896,26637361,30537593,30644739,31362590, b0154 ECK125286412 yadX b4765 175048 175095 forward protein YadX b4765 ECK120002206 clcA b0155 175107 176528 forward chloride:H antiporter ClcA b0155 ECK125276517 yadW b4728 176552 176617 forward protein YadW b4728 ECK120002207 erpA b0156 176610 176954 forward iron-sulfur cluster insertion protein ErpA b0156 ECK120002208 yadS b0157 177001 177624 reverse PF03458 family protein YadS 11790740,31438868, b0157 ECK120002209 btuF b0158 177662 178462 reverse vitamin B ABC transporter periplasmic binding protein 11574054,11790740,12468528,12475936,17073449,18358587, b0158 ECK120001078 mtn b0159 178455 179153 reverse 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 11489131,20080587,27067813,28927379,34580228, b0159 ECK120000219 dgt b0160 179237 180754 forward dGTP triphosphohydrolase 1677906,2165018,31019074, b0160 ECK120000456 degP b0161 180884 182308 forward periplasmic serine endoprotease DegP b0161 ECK120002210 cdaR b0162 182463 183620 forward DNA-binding transcriptional activator CdaR [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 10762278,14645248, Strong b0162 ECK120002211 yaeH b0163 183709 184095 reverse DUF3461 domain-containing protein YaeH b0163 ECK120002212 yaeI b0164 184257 185069 reverse phosphodiesterase YaeI [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 15808744, Weak b0164 ECK120002711 b0165 b0165 184987 185118 reverse ECK120000201 dapD b0166 185123 185947 reverse tetrahydrodipicolinate succinylase 10368155,1677906,3700390,6094577, b0166 ECK120001377 glnD b0167 185978 188650 reverse protein-PII uridylyltransferase/uridylyl-removing enzyme 16740928,239942,2868841,2868842,7629080,7961766, b0167 ECK120000563 map b0168 188712 189506 reverse methionine aminopeptidase 19889537,20207144, b0168 ECK120002606 tff b4414 189712 189847 forward putative small RNA T44 [COMP|W|Inferred by computational analysis] 11553332, Weak b4414 ECK120000892 rpsB b0169 189874 190599 forward 30S ribosomal subunit protein S2 30177741, b0169 ECK120001022 tsf b0170 190857 191708 forward protein chain elongation factor EF-Ts [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 17608803,21112298,21717022,344309,379535, Weak b0170 ECK120001493 pyrH b0171 191855 192580 forward UMP kinase b0171 ECK120000329 frr b0172 192872 193429 forward ribosome-recycling factor [EXP|W|Inferred from experiment],[EXP-IMP|W|Inferred from mutant phenotype] 10452886,15522083,1860827,2684966,3888114,6337880,782542,9258432,9463391, Weak b0172 ECK120002371 dxr b0173 193521 194717 forward 1-deoxy-D-xylulose 5-phosphate reductoisomerase b0173 ECK125302575 ispZ b4809 194784 194844 forward small regulatory RNA IspZ [EXP-IMP|W|Inferred from mutant phenotype] 33460557, Weak b4809 ECK120002712 ispU b0174 194903 195664 forward )-farnesyl-diphosphate specific] 25020247, b0174 ECK120000135 cdsA b0175 195677 196534 forward CDP-diglyceride synthetase 2995358, b0175 ECK120002290 rseP b0176 196546 197898 forward intramembrane zinc metalloprotease RseP [EXP-IDA|W|Inferred from direct assay],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IGI|W|Inferred from genetic interaction] 12183368,12183369,15066031,16513633,17179147,18268014,19706448,19717451,23016873,26447507,26716760,30914293,33329500, Weak b0176 ECK120002713 bamA b0177 197928 200360 forward outer membrane protein assembly factor BamA [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 15851030,16556215,17088246,17214547,17404237,17542925,19748339,20378773,22037403,22178970,22331884,22544271,22753067,24376817,24598928,25567766,25638436,25943387,26394056,26900875,27332128,28569500,30271910,30297837,31591200,31724945,32380170,32572278,33112853,34541845, Strong b0177 ECK120000448 skp b0178 200482 200967 forward periplasmic chaperone Skp 18293996,19693,19780589,22505681,22589188,28648612,3056922,330494,331078,33947759,6387397,7017348,8175698, b0178 ECK120000310 lpxD b0179 200971 201996 forward UDP-3--acyltransferase b0179 ECK120001257 fabZ b0180 202101 202556 forward 3-hydroxy-acyl-[acyl-carrier-protein] dehydratase b0180 ECK120000538 lpxA b0181 202560 203348 forward acyl-[acyl-carrier-protein]—UDP--acyltransferase b0181 ECK120000539 lpxB b0182 203348 204496 forward lipid A disaccharide synthase b0182 ECK120000852 rnhB b0183 204493 205089 forward RNase HII b0183 ECK120000232 dnaE b0184 205126 208608 forward DNA polymerase III subunit α 6288664, b0184 ECK120001591 accA b0185 208621 209580 forward acetyl-CoA carboxyltransferase subunit α b0185 ECK120002714 ldcC b0186 209679 211820 forward lysine decarboxylase 2 26383169, b0186 ECK120002715 yaeR b0187 211877 212266 forward VOC domain-containing protein YaeR b0187 ECK120002716 tilS b0188 212331 213629 forward tRNA-lysidine synthetase 24820111, b0188 ECK120002717 rof b0189 213678 213932 reverse modulator of Rho-dependent transcription termination [EXP|W|Inferred from experiment],[EXP-IMP|W|Inferred from mutant phenotype] 15836776,17565995,9723924, Weak b0189 ECK120002691 yaeP b4406 213925 214125 reverse PF06786 family protein YaeP b4406 ECK120002718 yaeQ b0190 214291 214836 forward uncharacterized protein YaeQ 32117137, b0190 ECK120002223 arfB b0191 214833 215255 forward peptidyl-tRNA hydrolase, ribosome rescue factor 22427623,24322300, b0191 ECK120002038 nlpE b0192 215269 215979 forward sensor lipoprotein NlpE [EXP-IDA|W|Inferred from direct assay],[EXP-IGI|W|Inferred from genetic interaction] 20211889,28416660,30833359,32053772,7635807,9023180, Weak b0192 ECK120002039 yaeF b0193 216179 217003 reverse peptidase C92 family protein YaeF 11574054,32053772, b0193 ECK120000761 proS b0194 217057 218775 reverse proline—tRNA ligase 24443971,25464974,31542226,32681406,34761260, b0194 ECK120001459 trmO b0195 218887 219594 reverse tRNA mA37 methyltransferase b0195 ECK120001458 rcsF b0196 219591 219995 reverse sensor lipoprotein RcsF [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 12410838,13129944,1459951,15375134,16166540,19136591,23893115,25525882,29257832,30782633,31113901,31113910,32053772,32094588,9209051, Weak b0196 ECK120001460 metQ b0197 220113 220928 reverse L-methionine/D-methionine ABC transporter membrane anchored binding protein 12218041,15174130,32053772, b0197 ECK120001676 metI b0198 220968 221621 reverse L-methionine/D-methionine ABC transporter membrane subunit 12218041, b0198 ECK120001569 metN b0199 221614 222645 reverse L-methionine/D-methionine ABC transporter ATP binding subunit 12169620,12218041, b0199 ECK120001675 gmhB b0200 222833 223408 forward D--heptose-1,7-bisphosphate 7-phosphatase 24412338,32606320, b0200 ECK120002532 rrsH b0201 223771 225312 forward 16S ribosomal RNA 10753935,10844684,10919826,1094419,1101264,1102922,1103124,110460,11751827,12087167,12498,12902289,12903214,14510386,1646122,1716101,1718749,1764510,1764516,2145040,2168847,2222527,2387410,2435709,2443830,2448485,2473375,2685545,2689447,2833391,3013618,3071662,3071664,319193,320561,326259,327272,327273,3277949,331075,331313,3313279,3329282,342117,344139,348233,365689,378405,383432,384145,3894326,390405,392468,407931,4560773,4564202,4918356,4942898,4943519,6285294,6330033,6361011,6752954,6995826,7516168,7601845,769922,7718670,782716,782717,789334,793615,8041615,8312257,8377198,8419334,8515441,9034358,9226253,9501232,9769102, b0201 ECK120002487 ileV b0202 225381 225457 forward tRNA-Ile(GAU) [AS-TAS|W|Traceable author statement] 7033244, Weak b0202 ECK120002453 alaV b0203 225500 225575 forward tRNA-Ala(UGC) [AS-TAS|W|Traceable author statement] 7033244, Weak b0203 ECK120002525 rrlH b0204 225759 228662 forward 23S ribosomal RNA [EXP-TAS|W|Traceable author statement to experimental support] 10051579,10464195,10525403,10793686,10844684,1094419,10964562,10986461,1098691,1101264,1102922,1103090,1103124,11157269,11350034,11517305,11574482,11675490,11680845,11741781,11751827,11888286,11955006,11991636,12022228,12034826,12467398,12498,12533472,12888505,1719209,1918155,1981803,2197598,2407189,2473375,3013618,3048270,3053641,3060850,3089782,319193,319197,3226909,325525,327272,327273,3277949,329865,331075,331313,3313279,3329282,342117,355851,359042,388189,3894326,390405,407931,4563865,4584388,4918356,4931952,4942898,4943519,6158039,6162473,6170632,6173374,6193815,6255418,6349628,6361011,6750359,6996708,7016337,7041903,7514294,7529560,7567991,7601845,7682175,775291,782716,782717,785385,789334,791272,8031879,805122,8253085,8515441,8524828,8643399,8643630,8654409,8710862,8834779,8918803,9016593,9034358,9135982,9367788,9396814,9501232,9573162,9586034,9620960,9769102,9836593,9989214, Weak b0204 ECK120002518 rrfH b0205 228756 228875 forward 5S ribosomal RNA [EXP-TAS|W|Traceable author statement to experimental support] 11401702,11488615,164889,1709493,1709723,1718749,1764510,2190187,2412207,2493632,3013618,3089782,324975,327272,331075,3315008,342117,359042,4198187,4216514,4550693,4571522,4591367,4609878,4621557,4881049,4881332,4906324,4906608,4918254,4920877,4924729,4931952,4944480,4993318,6178431,6188537,6255417,6390428,6765232,7024913,782717,805122,810137,95791,9862991,9878392, Weak b0205 ECK120002467 aspU b0206 228928 229004 forward tRNA-Asp(GUC) [AS-TAS|W|Traceable author statement] 7033244, Weak b0206 ECK120001592 dkgB b0207 229167 229970 forward methylglyoxal reductase DkgB b0207 ECK120001593 yafC b0208 229967 230881 reverse DNA-binding transcriptional regulator YafC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IPI|W|Inferred from physical interaction] 15556475,30137486, Weak b0208 ECK120001594 yafD b0209 231122 231922 forward endonuclease/exonuclease/phosphatase domain-containing protein YafD b0209 ECK120001595 yafE b0210 231926 232549 forward putative S-adenosylmethionine-dependent methyltransferase b0210 ECK120000240 mltD b0211 232597 233955 reverse membrane-bound lytic murein transglycosylase D 10843862,11139297,1663890,32053772,8203016, b0211 ECK120002719 gloB b0212 234027 234782 reverse hydroxyacylglutathione hydrolase GloB 27861552, b0212 ECK125303708 ykfO b4815 234288 234320 forward protein YkfO b4815 ECK120002720 yafS b0213 234816 235538 forward putative S-adenosyl-L-methionine-dependent methyltransferase b0213 ECK120000851 rnhA b0214 235535 236002 reverse ribonuclease HI b0214 ECK120000237 dnaQ b0215 236067 236798 forward DNA polymerase III subunit ε 6325441,6359162, b0215 ECK120002468 aspV b0216 236931 237007 forward tRNA-Asp(GUC) [AS-TAS|W|Traceable author statement] 3295485,7033244, Weak b0216 ECK120002721 yafT b0217 237335 238120 forward lipoprotein YafT 32053772, b0217 ECK120030067 ykfM b4586 238257 238736 reverse uncharacterized protein YkfM b4586 ECK120002607 C0067 238462 238586 forward ECK120002722 yafU b0218 238746 239084 reverse putative inner membrane protein 24391520, b0218 ECK120016283 yafF b4503 239190 239378 forward putative uncharacterized protein YafF b4503 ECK120002723 yafV b0219 239419 240189 reverse 2-oxoglutaramate amidase b0219 ECK120002724 ivy b0220 240343 240816 forward periplasmic chaperone, inhibitor of vertebrate C-type lysozyme b0220 ECK120002725 fadE b0221 240859 243303 reverse acyl-CoA dehydrogenase 1097444,12694916,16385050,23656231,29369593,350850,374354,6355101, b0221 ECK120002726 gmhA b0222 243543 244121 forward D-sedoheptulose 7-phosphate isomerase 23843301, b0222 ECK120002727 yafJ b0223 244327 245094 forward putative glutamine amidotransferase YafJ b0223 ECK120002728 dpaA b0224 245065 245805 reverse peptidoglycan -diaminopimelic acid protein amidase A 30233559,30275297,31743648, b0224 ECK120002729 yafQ b0225 245961 246239 reverse ribosome-dependent mRNA interferase toxin YafQ 24923448, b0225 ECK120002730 dinJ b0226 246242 246502 reverse antitoxin/DNA-binding transcriptional repressor DinJ b0226 ECK120002731 yafL b0227 246712 247461 forward NlpC/P60 family protein YafL 24391520,32053772, b0227 ECK120002732 rayT b0228 247637 248134 forward REP-associated tyrosine transposase [EXP-IDA|W|Inferred from direct assay] 21698139,22199259,25636231, Weak b0228 ECK120002733 lfhA b0229 248358 250070 reverse flagellar system protein, promoterless fragment b0229 ECK120002734 lafU b0230 250072 250827 forward flagellar system protein, promoterless fragment b0230 ECK120002735 dinB b0231 250898 251953 forward DNA polymerase IV 10320582,11069662,11124950,11459972,11573000,11587937,11734560,12060704,12097328,12509239,12606122,12754247,14617178,14729336,15141361,15339923,15687217,15827613,16338175,16386932,16482223,16483853,16904387,17397877,17635192,18761688,19188081,19270270,19843218,20472798,20523737,20639336,21477595,22820381,23229309,23525461,24243543,25301949,25899385,26523515,28298904,28727736,29255195,2940594,29468195,29850882,29907648,30087411,31810989,33386487, b0231 ECK120002736 yafN b0232 252005 252298 forward antitoxin YafN [EXP-IDA|W|Inferred from direct assay] 19617347,22869116,24657250, Weak b0232 ECK120002737 yafO b0233 252301 252699 forward ribosome-dependent mRNA interferase toxin YafO [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 14594833,19617347,22869116, Weak b0233 ECK120002738 yafP b0234 252709 253161 forward putative -acetyltransferase YafP b0234 ECK120002739 ykfJ b0235 253467 253733 forward RNA ligase superfamily protein YkfJ b0235 ECK120001452 prfH b0236 253702 254202 forward putative peptide chain release factor [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 1408743, Weak b0236 ECK120000687 pepD b0237 254259 255716 reverse peptidase D 1938933,21905274,2651887, b0237 ECK120000407 gpt b0238 255977 256435 forward xanthine-guanine phsophoribosyltransferase b0238 ECK120001079 frsA b0239 256527 257771 forward fermentation-respiration switch protein [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 15169777,15808744, Weak b0239 ECK125229290 insB9 b4710 257923 258426 reverse IS1 transposase B b4710 ECK125229291 insA9 b4709 258345 258620 reverse IS1 repressor TnpA b4709 ECK120000720 phoE b0241 259045 260100 reverse outer membrane porin PhoE b0241 ECK120000759 proB b0242 260388 261491 forward glutamate 5-kinase b0242 ECK120000758 proA b0243 261503 262756 forward glutamate-5-semialdehyde dehydrogenase b0243 ECK120002546 thrW b0244 262871 262946 forward tRNA-Thr(CGU) [AS-TAS|W|Traceable author statement] 6761541,7033244, Weak b0244 ECK125276499 ykfN b4626 263150 263212 reverse YdiA family protein b4626 ECK120002740 ykfI b0245 263328 263669 reverse CP4-6 prophage; toxin of the YkfI-YafW toxin-antitoxin system [EXP-IMP|W|Inferred from mutant phenotype] 14594833, Weak b0245 ECK120002741 yafW b0246 263690 264007 reverse antitoxin of the YkfI-YafW toxin-antitoxin pair [EXP-IDA-UNPURIFIED-PROTEIN-NH|W|Assay of unpurified protein expressed in its native host] 14594833, Weak b0246 ECK120016284 ykfH b4504 264026 264247 reverse DUF987 domain-containing protein YkfH b4504 ECK120002742 ykfG b0247 264256 264732 reverse CP4-6 prophage; RadC-like JAB domain-containing protein YkfG b0247 ECK120002743 yafX b0248 264748 265206 reverse CP4-6 prophage; protein YafX b0248 ECK120002744 ykfF b0249 265304 265543 reverse CP4-6 prophage; protein YkfF b0249 ECK120002745 ykfB b0250 265620 266087 reverse CP4-6 prophage; protein YkfB b0250 ECK120002746 yafY b0251 266110 266553 reverse CP4-6 prophage; inner membrane lipoprotein YafY 32053772, b0251 ECK120033231 ykfL b4627 266553 266774 reverse b4627 ECK120033232 ykfK b4628 266776 266967 reverse b4628 ECK120002747 yafZ b0252 267184 268005 reverse CP4-6 prophage; DUF932 domain-containing protein YafZ b0252 ECK120002748 ykfA b0253 268097 268960 reverse CP4-6 prophage; putative GTP-binding protein YkfA b0253 ECK120002749 perR b0254 269289 270182 reverse CP4-6 prophage; putative transcriptional regulator PerR [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15556475, Weak b0254 ECK120002751 insI1 b0256 270603 271754 forward IS30 transposase b0256 ECK125135291 eyeA b4690 272580 272654 forward CP4-6 prophage; small RNA EyeA b4690 ECK120002753 ykfC b0258 272847 273992 forward CP4-6 prophage; PF00078 domain-containing protein YkfC b0258 ECK120002754 insH1 b0259 274101 275081 reverse CP4-6 prophage; IS transposase and trans-activator b0259 ECK120002755 mmuP b0260 275325 276728 forward CP4-6 prophage; -methyl-L-methionine transporter b0260 ECK120002756 mmuM b0261 276715 277647 forward CP4-6 prophage; homocysteine -methyltransferase 25552925, b0261 ECK120002215 afuC b0262 277756 278802 reverse CP4-6 prophage; ABC transporter ATP-binding protein AfuC [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 16397293, Weak b0262 ECK120002757 afuB b0263 278814 279162 reverse CP4-6 prophage; ABC transporter membrane protein AfuB b0263 ECK120002758 insB2 b0264 279178 279681 reverse IS1 protein InsB [EXP-IMP|W|Inferred from mutant phenotype] 8083181, Weak b0264 ECK120023913 insAB2 279178 279875 reverse InsAB' transposase [EXP-IMP|W|Inferred from mutant phenotype] 8083181, Weak ECK120002759 insA2 b0265 279600 279875 reverse IS1 protein InsA [EXP-IMP|W|Inferred from mutant phenotype] 8083181, Weak b0265 ECK125240991 insI2 b4708 279931 280104 forward b4708 ECK120016285 insX b4505 280114 280362 reverse b4505 ECK120002214 yagB b0266 280385 280735 reverse CP4-6 prophage; orphan antitoxin YagB b0266 ECK120002213 yagA b0267 280829 281983 reverse CP4-6 prophage; integrase core domain-containing protein YagA b0267 ECK120002760 yagE b0268 282278 283186 forward CP4-6 prophage; putative 2-dehydro-3-deoxygluconate aldolase b0268 ECK120002761 yagF b0269 283201 285168 forward CP4-6 prophage; D-xylonate dehydratase 29392388, b0269 ECK120002762 yagG b0270 285395 286777 forward CP4-6 prophage; putative D-xylonate transporter YagG 11750821, b0270 ECK120002763 yagH b0271 286789 288399 forward CP4-6 prophage; putative xylosidase/arabinosidase b0271 ECK120002764 xynR b0272 288404 289162 reverse CP4-6 prophage; DNA-binding transcriptional repressor XynR [COMP-AINF|W|Inferred computationally without human oversight],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 15556475,29087459, Strong b0272 ECK120000063 argF b0273 289301 290305 reverse CP4-6 prophage; ornithine carbamoyltransferase ArgF b0273 ECK125286387 argL b4766 290275 290370 reverse putative translational regulatory protein ArgL [EXP-IMP|W|Inferred from mutant phenotype] 30837344, Weak b4766 ECK125240987 ykgS b4688 290510 290638 forward CP4-6 prophage; protein YkgS b4688 ECK120002765 insB3 b0274 290649 291152 reverse IS1 protein InsB b0274 ECK120023914 insAB3 290649 291346 reverse InsAB' transposase ECK120002766 insA3 b0275 291071 291346 reverse IS1 protein InsA b0275 ECK120002767 yagJ b0276 291500 292231 forward CP4-6 prophage; protein YagJ b0276 ECK120002768 yagK b0277 292322 292948 reverse CP4-6 prophage; uncharacterized protein YagK b0277 ECK120002769 yagL b0278 293220 293918 reverse CP4-6 prophage; resolvase-like catalytic domain-containing protein YagL b0278 ECK120002770 yagM b0279 293945 294799 reverse CP4-6 prophage; protein YagM b0279 ECK125276526 ykgV b4729 294918 295142 reverse CP4-6 prophage; protein YkgV b4729 ECK120002771 yagN b0280 295139 295579 reverse CP4-6 prophage; protein YagN b0280 ECK120002772 intF b0281 295696 297096 reverse CP4-6 prophage; putative phage integrase 27718375, b0281 ECK125146691 nc1 297137 297304 reverse small noncoding RNA involved in nucleoid organization [EXP-IMP|W|Inferred from mutant phenotype] 22942248, Weak ECK120002773 yagP b0282 297381 297791 reverse putative LysR family substrate binding domain-containing protein YagP b0282,b4695 ECK120002774 paoD b0283 297770 298726 reverse molybdenum cofactor insertion chaperone PaoD b0283 ECK120002775 paoC b0284 298736 300934 reverse aldehyde dehydrogenase: molybdenum cofactor-binding subunit b0284 ECK120002776 paoB b0285 300931 301887 reverse aldehyde dehydrogenase, FAD-binding subunit b0285 ECK120002777 paoA b0286 301884 302573 reverse aldehyde dehydrogenase, Fe-S subunit b0286 ECK120002778 yagU b0287 302991 303605 forward DUF1440 domain-containing inner membrane protein YagU b0287 ECK120002779 ykgJ b0288 303853 304182 reverse putative metal-chelating domain-containing protein YkgJ 24391520, b0288 ECK120002780 ecpE b0289 304495 305205 reverse putative fimbrial chaperone EcpE 20345943,23382825, b0289 ECK120002781 ecpD b0290 305174 306817 reverse fimbrial adhesin EcpD 20345943,23382825, b0290 ECK120002782 ecpC b0291 306807 309332 reverse putative fimbrial usher protein EcpC 20345943,23382825, b0291 ECK120002783 ecpB b0292 309358 310026 reverse putative fimbrial chaperone EcpB 20345943,23382825, b0292 ECK120002784 ecpA b0293 310084 310671 reverse common pilus major subunit [COMP|W|Inferred by computational analysis],[EXP-IMP|W|Inferred from mutant phenotype] 11466275,17563352,20345943,20522494,23382825, Weak b0293 ECK120002785 matA b0294 310746 311336 reverse DNA-binding transcriptional dual regulator MatA [EXP-IEP|W|Inferred from expression pattern],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 15556475,22422754, Strong b0294 ECK120002786 ykgL b0295 312112 312339 forward uncharacterized protein YkgL b0295 ECK120016286 ykgO b4506 312374 312514 reverse 50S ribosomal subunit protein L36B [EXP-IDA|W|Inferred from direct assay] 30359641, Weak b4506 ECK120002787 ykgM b0296 312514 312777 reverse 50S ribosomal subunit protein L31B [EXP-IDA|W|Inferred from direct assay],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 11574053,19377097,22016571,30359641, Weak b0296 ECK120048866 ykgR b4671 313141 313242 reverse uncharacterized membrane protein YkgR b4671 ECK125276501 ykgP b4630 313716 313805 reverse putative oxidoreductase b4630 ECK120002057 eaeH b0297 314357 315244 forward putative porin domain-containing protein EaeH [COMP|W|Inferred by computational analysis] Weak b0297 ECK120002788 insE1 b0298 315291 315590 forward IS3 element protein InsE [EXP-IDA|W|Inferred from direct assay] 8107082, Weak b0298 ECK120023906 insEF1 315291 316453 forward IS3 element transposase [EXP-IDA|W|Inferred from direct assay] 8107082, Weak ECK120002789 insF1 b0299 315587 316453 forward IS3 element protein InsF [EXP-IDA|W|Inferred from direct assay] 8107082, Weak b0299 ECK120002790 ykgA b0300 316450 317136 reverse putative DNA-binding transcriptional regulator YkgA [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b0300 ECK125095416 ykgQ b4631 317439 317567 forward b4631 ECK120002791 rclC b0301 317726 318319 reverse DUF417 domain-containing inner membrane protein RclC [EXP-IMP|W|Inferred from mutant phenotype] 24078635, Weak b0301 ECK120002792 rclB b0303 318331 318567 reverse DUF1471 domain-containing protein RclB [EXP-IMP|W|Inferred from mutant phenotype] 24078635, Weak b0303 ECK120002793 rclA b0304 318676 320001 reverse cupric reductase RclA b0304 ECK120002794 rclR b0305 320227 321081 forward DNA-binding transcriptional activator RclR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b0305 ECK120002795 ykgE b0306 321608 322327 forward putative lactate utilization oxidoreductase YkgE [EXP-IGI|W|Inferred from genetic interaction] 19196979,19201793, Weak b0306 ECK120002796 ykgF b0307 322338 323765 forward putative amino acid dehydrogenase with NAD(P)-binding domain and ferridoxin-like domain b0307 ECK120002797 ykgG b0308 323758 324453 forward DUF162 domain-containing lactate utilization protein YkgG 19201793, b0308 ECK120002798 b0309 b0309 324408 324620 reverse ECK120002799 ykgH b0310 324696 325364 reverse uncharacterized protein YkgH b0310 ECK120000105 betA b0311 325577 327247 reverse choline dehydrogenase b0311 ECK120000106 betB b0312 327261 328733 reverse betaine aldehyde dehydrogenase 1956285,23295228,3512526, b0312 ECK120000107 betI b0313 328747 329334 reverse DNA-binding transcriptional repressor BetI [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 1956285,8626295, Weak b0313 ECK120000108 betT b0314 329463 331496 forward choline:H symporter b0314 ECK125276505 yahV b4730 331802 331876 forward protein YahV b4730 ECK120001214 pdeL b0315 332371 333459 forward DNA-binding transcriptional regulator/c-di-GMP phosphodiesterase PdeL b0315 ECK120002800 yahB b0316 333501 334433 reverse putative LysR-type DNA-binding transcriptional regulator YahB [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b0316 ECK120002801 yahC b0317 334525 335022 reverse uncharacterized protein YahC b0317 ECK120002802 yahD b0318 335280 335885 forward ankyrin repeat-containing protein YahD b0318 ECK120002803 yahE b0319 335925 336788 forward DUF2877 domain-containing protein YahE b0319 ECK120002804 yahF b0320 336778 338325 forward putative acyl-CoA synthetase YahF b0320 ECK120002805 yahG b0321 338325 339743 forward DUF1116 domain-containing protein YahG b0321 ECK120026444 yahH b0322 339769 340089 forward putative uncharacterized protein YahH b0322 ECK120002806 yahI b0323 340165 341115 forward carbamate kinase-like protein YahI b0323 ECK120002807 yahJ b0324 341125 342507 forward amidohydrolase family protein YahJ b0324 ECK120002808 yahK b0325 342884 343933 forward aldehyde reductase, NADPH-dependent b0325 ECK120002809 yahL b0326 344176 344991 forward uncharacterized protein YahL b0326 ECK120002810 yahM b0327 345404 345649 forward uncharacterized protein YahM b0327 ECK120002811 yahN b0328 345666 346337 reverse putative amino acid exporter YahN 12879215,31438868, b0328 ECK120002812 yahO b0329 346484 346759 forward DUF1471 domain-containing protein YahO 29802191, b0329 ECK120002813 prpR b0330 346857 348443 reverse DNA-binding transcriptional dual regulator PrpR [EXP-IDA|W|Inferred from direct assay] 15805526,27718375, Weak b0330 ECK120002814 prpB b0331 348682 349572 forward 2-methylisocitrate lyase b0331 ECK120002815 prpC b0333 350012 351181 forward 2-methylcitrate synthase b0333 ECK120002816 prpD b0334 351215 352666 forward 2-methylcitrate dehydratase b0334 ECK120002817 prpE b0335 352706 354592 forward propionyl-CoA synthetase 19806677,22118660,22923122,25048226,25621933,30681833, b0335 ECK120001298 codB b0336 354922 356181 forward cytosine transporter b0336 ECK120001297 codA b0337 356171 357454 forward cytosine/isoguanine deaminase 8450832, b0337 ECK120001385 cynR b0338 357791 358690 reverse DNA-binding transcriptional dual regulator CynR 1592818,7961413,8253686, b0338 ECK120000171 cynT b0339 358799 359458 forward carbonic anhydrase 1 b0339 ECK120000170 cynS b0340 359489 359959 forward cyanase b0340 ECK120000172 cynX b0341 359992 361146 forward cyanate transporter 2670891, b0341 ECK120000517 lacA b0342 361249 361860 reverse galactoside -acetyltransferase 3901000, b0342 ECK120000519 lacY b0343 361926 363179 reverse lactose permease 11523990,15364943,16566592,18620422,19128028,19383792,20875429,21254783,21593407,21896727,23000385,23012238,23671103,24513108,25512549,26512108,26512118,27686537,27791182,28154138,30254312,30478058,30792352,32499529,336372,6206889,6350295,6378637,6379649,6757923,7756986,8003960,8318887,8993343,9159108, b0343 ECK120000520 lacZ b0344 363231 366305 reverse β-galactosidase b0344 ECK120000518 lacI b0345 366428 367510 reverse DNA-binding transcriptional repressor LacI [EXP|W|Inferred from experiment] 1107032,13718526,14430363,2040302,2178920,2742823,3064080,3286877,355891,4571224,4594037,8046748, Weak b0345 ECK120002818 mhpR b0346 367587 368420 reverse DNA-binding transcriptional activator MhpR 12748194, b0346 ECK120004469 mhpA b0347 368611 370275 forward 3-(3-hydroxyphenyl)propanoate hydroxylase 31811039, b0347 ECK120004470 mhpB b0348 370277 371221 forward 3-carboxyethylcatechol 2,3-dioxygenase b0348 ECK120004471 mhpC b0349 371239 372105 forward 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase b0349 ECK120004472 mhpD b0350 372115 372924 forward 2-hydroxypentadienoate hydratase b0350 ECK120004473 mhpF b0351 372921 373871 forward acetaldehyde dehydrogenase (acetylating) MhpF 19915031,21400237,23896974,24004455,24269999,26384570,29188185, b0351 ECK120002819 mhpE b0352 373868 374881 forward 4-hydroxy-2-oxovalerate aldolase b0352 ECK120002820 mhpT b0353 375459 376670 forward 3-hydroxyphenylpropionate/3-hydroxycinnamate:H symporter b0353 ECK120002821 yaiL b0354 376772 377311 forward DUF2058 domain-containing protein YaiL b0354 ECK120002822 frmB b0355 377535 378368 reverse -formylglutathione hydrolase FrmB b0355 ECK120002569 frmA b0356 378462 379571 reverse -(hydroxymethyl)glutathione dehydrogenase b0356 ECK120002823 frmR b0357 379606 379881 reverse DNA-binding transcriptional repressor FrmR b0357 ECK120002824 yaiO b0358 380069 380842 reverse outer membrane protein YaiO 26040540, b0358 ECK120002826 insC1 b0360 381351 381716 forward IS2 element protein InsA b0360 ECK120023917 insCD1 381351 382579 forward IS2 element transposase InsAB' [EXP-IMP|W|Inferred from mutant phenotype] 8824609, Weak ECK120002827 insD1 b0361 381674 382579 forward IS2 element protein b0361 ECK120002829 yaiP b0363 382739 383935 reverse putative glucosyltransferase b0363 ECK125276515 ykiC b4731 383960 384079 forward protein YkiC b4731 ECK120002830 yaiS b0364 384059 384616 reverse putative deacetylase YaiS 24391520, b0364 ECK120002831 tauA b0365 385232 386194 forward taurine ABC transporter periplasmic binding protein 8808933, b0365 ECK120002832 tauB b0366 386207 386974 forward taurine ABC transporter ATP binding subunit b0366 ECK120002833 tauC b0367 386971 387798 forward taurine ABC transporter membrane subunit b0367 ECK120002281 tauD b0368 387795 388646 forward taurine dioxygenase b0368 ECK120000421 hemB b0369 388753 389727 reverse porphobilinogen synthase 126586,142040,1551829,19095441,1987138,24188714,2464127,2656410,3276659,7842862,7968676,8144481,9033406,9260292,9761921,9766004, b0369 ECK120002834 ykiB b0370 389897 390115 reverse b0370 ECK125286423 ytiB b4767 391592 391648 reverse protein YtiB b4767 ECK120023908 insEF2 391739 392901 reverse IS3 element transposase ECK120002836 insF2 b0372 391739 392605 reverse IS3 element protein InsF b0372 ECK120002837 insE2 b0373 392602 392901 reverse IS3 element protein InsE b0373 ECK120002839 iprA b0375 394506 395129 forward putative DNA-binding transcriptional regulator IprA [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 15556475,27246569, Weak b0375 ECK120002410 ampH b0376 395130 396287 reverse peptidoglycan DD-carboxypeptidase/peptidoglycan DD-endopeptidase 34382698, b0376 ECK120000917 sbmA b0377 396639 397859 forward peptide antibiotic/peptide nucleic acid transporter b0377 ECK120002840 yaiW b0378 397872 398966 forward surface-exposed outer membrane lipoprotein [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IDA-UNPURIFIED-PROTEIN-NH|W|Assay of unpurified protein expressed in its native host],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 10734204,15556475,24214946, Weak b0378 ECK120002841 yaiY b0379 399025 399333 reverse DUF2755 domain-containing inner membrane protein YaiY 32268068, b0379 ECK120002842 yaiZ b0380 399593 399805 forward DUF2754 domain-containing protein YaiZ b0380 ECK120000207 ddlA b0381 399829 400923 reverse D-alanine—D-alanine ligase A b0381 ECK120001231 iraP b0382 401386 401646 forward anti-adaptor protein IraP [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 16600914,26979278, Weak b0382 ECK120000718 phoA b0383 401747 403162 forward alkaline phosphatase 11884134,13666805,323853,33410323,4319108,4879556,4979102,6273802,6339478,7012129,8520475,8652582, b0383 ECK120001367 psiF b0384 403281 403601 forward phosphate starvation-inducible protein PsiF 3533724, b0384 ECK120001232 dgcC b0385 403703 404818 forward diguanylate cyclase DgcC b0385 ECK120000760 proC b0386 404835 405644 reverse pyrroline-5-carboxylate reductase b0386 ECK120002843 yaiI b0387 405764 406222 forward DUF188 domain-containing protein YaiI b0387 ECK120000078 aroL b0388 406405 406929 forward shikimate kinase 2 1309529,3001025,3001029,3026317, b0388 ECK120001081 yaiA b0389 406979 407170 forward protein YaiA b0389 ECK120000079 aroM b0390 407428 408105 forward protein AroM b0390 ECK120002056 ppnP b0391 408177 408461 forward nucleoside phosphorylase PpnP b0391 ECK120002844 ykiA b0392 408609 408950 forward DUF2773 domain-containing protein YkiA b0392 ECK125276524 ykiD b4732 408947 409030 forward protein YkiD b4732 ECK120002055 rdgC b0393 409108 410019 reverse nucleoid-associated protein RdgC [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10655207,16377615, Strong b0393 ECK120001261 mak b0394 410144 411052 forward fructokinase 17159144, b0394 ECK120000056 araJ b0396 411297 412481 reverse putative transport protein AraJ b0396 ECK120000916 sbcC b0397 412607 415753 reverse ATP-dependent structure-specific DNA nuclease - SbcC subunit 3932331, b0397 ECK120001082 sbcD b0398 415750 416952 reverse ATP-dependent structure-specific DNA nuclease - SbcD subunit 31683605, b0398 ECK120000719 phoB b0399 417142 417831 forward DNA-binding transcriptional dual regulator PhoB [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 10986267,1482126,2157156,3054125,324866,3537313,6310121,6343798,7009567,7699720,7855419,8098993, Weak b0399 ECK120000724 phoR b0400 417889 419184 forward sensor histidine kinase PhoR b0400 ECK120002064 brnQ b0401 419591 420910 forward branched chain amino acid transporter BrnQ 32518189, b0401 ECK120002845 proY b0402 420986 422359 forward putative transporter ProY b0402 ECK120000558 malZ b0403 422518 424332 forward maltodextrin glucosidase b0403 ECK120001083 acpH b0404 424337 424918 reverse acyl carrier protein phosphodiesterase b0404 ECK120000803 queA b0405 425011 426081 forward tRNA preQ-adenosylmethionine ribosyltransferase-isomerase b0405 ECK120000985 tgt b0406 426137 427264 forward tRNA-guanine transglycosylase 12480882,12756333,6204866,7833029, b0406 ECK120001084 yajC b0407 427287 427619 forward Sec translocon accessory complex subunit YajC [EXP-IPI|W|Inferred from physical interaction],[EXP-IGI|W|Inferred from genetic interaction] 10675323,11051763,11707277,12068816,12935896,7507921,8190079,9184221,9305629, Weak b0407 ECK120000927 secD b0408 427647 429494 forward Sec translocon accessory complex subunit SecD 1633199,8021192, b0408 ECK120000929 secF b0409 429505 430476 forward Sec translocon accessory complex subunit SecF 1633199,8021192, b0409 ECK120001085 yajD b0410 430605 430952 forward HNH nuclease family protein YajD b0410 ECK120001024 tsx b0411 431129 432013 reverse nucleoside-specific channel-forming protein Tsx 15272310,30125859,30271910,374403, b0411 ECK120002413 yajI b0412 432312 432851 reverse putative lipoprotein YajI 32053772, b0412 ECK120001291 nrdR b0413 433002 433451 forward NrdR transcriptional repressor b0413 ECK120001292 ribD b0414 433455 434558 forward fused diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase b0414 ECK120001293 ribE b0415 434647 435117 forward 6,7-dimethyl-8-ribityllumazine synthase b0415 ECK120000659 nusB b0416 435137 435556 forward transcription antitermination protein NusB [EXP-IMP|W|Inferred from mutant phenotype] 6272065,7045592, Weak b0416 ECK120002846 thiL b0417 435634 436611 forward thiamine monophosphate kinase b0417 ECK120000696 pgpA b0418 436589 437107 forward phosphatidylglycerophosphatase A 1309518, b0418 ECK120002847 yajO b0419 437161 438135 reverse 1-deoxyxylulose-5-phosphate synthase YajO [EXP|W|Inferred from experiment],[EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation] 15292217,23383054,25326299, Strong b0419 ECK120002848 dxs b0420 438315 440177 reverse 1-deoxy-D-xylulose-5-phosphate synthase b0420 ECK120000501 ispA b0421 440202 441101 reverse geranyl diphosphate/farnesyl diphosphate synthase 2661529, b0421 ECK120001086 xseB b0422 441101 441343 reverse exodeoxyribonuclease VII subunit XseB b0422 ECK120002849 thiI b0423 441549 442997 forward tRNA uridine 4-sulfurtransferase 10781607,1383926,14705641,16855700,20404999,20715575,2120405,2180904,22081593,2449211,2653100,3514208,396815,405149,409535,4551941,6178725, b0423 ECK120002673 yajL b0424 443051 443641 reverse protein/nucleic acid deglycase 3 b0424 ECK120002850 panE b0425 443604 444515 reverse 2-dehydropantoate 2-reductase 19636932, b0425 ECK120002851 yajQ b0426 444683 445174 forward nucleotide binding protein YajQ b0426 ECK120002852 yajR b0427 445302 446666 reverse putative transport protein YajR 23950222,31438868, b0427 ECK120000177 cyoE b0428 446815 447705 reverse heme O synthase 7885224, b0428 ECK120000176 cyoD b0429 447717 448046 reverse cytochrome subunit 4 b0429 ECK120000175 cyoC b0430 448046 448660 reverse cytochrome subunit 3 b0430 ECK120000174 cyoB b0431 448650 450641 reverse cytochrome subunit 1 18983149,19584547,30281793,8218180,8885841,8885842, b0431 ECK120000173 cyoA b0432 450663 451610 reverse cytochrome subunit 2 11017202,15126489,15174130,26100898,28553265,32053772,7961841,8433374, b0432 ECK120002076 ampG b0433 452070 453545 reverse muropeptide:H symporter 27442597, b0433 ECK120002075 yajG b0434 453589 454167 reverse putative lipoprotein YajG 32053772, b0434 ECK120000121 bolA b0435 454472 454789 forward DNA-binding transcriptional dual regulator BolA [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 12354237,2684651,3053647, Weak b0435 ECK120000992 tig b0436 455133 456431 forward trigger factor 10380927,11592405,11902726,12756233,15175291,15308339,16421097,16551615,20096367,3046750,3049077,8612805,9868784, b0436 ECK120000154 clpP b0437 456677 457300 forward ATP-dependent Clp protease proteolytic subunit b0437 ECK120000155 clpX b0438 457426 458700 forward ATP-dependent Clp protease ATP-binding subunit ClpX b0438 ECK120002574 sraA 458728 458784 reverse small RNA SraA 11448770,11553332, ECK120000535 lon b0439 458888 461242 forward Lon protease 27718375, b0439 ECK120000460 hupB b0440 461451 461723 forward DNA-binding protein HU-β b0440 ECK120002853 ppiD b0441 461915 463786 forward periplasmic folding chaperone [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 20920237,24951590,29097228,31699901,33531386, Strong b0441 ECK120002854 ybaV b0442 463937 464308 forward helix-hairpin-helix 3 family protein [EXP-IMP|W|Inferred from mutant phenotype] 23131563, Weak b0442 ECK120002855 fadM b0443 464402 464800 forward long-chain acyl-CoA thioesterase FadM b0443 ECK120002856 queC b0444 464852 465547 reverse 7-cyano-7-deazaguanine synthase b0444 ECK120002431 ybaE b0445 465612 467312 reverse uncharacterized protein YbaE 16397293, b0445 ECK120002857 cof b0446 467412 468230 forward HMP-PP phosphatase b0446 ECK120002858 decR b0447 468383 468841 forward DNA-binding transcriptional activator DecR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-PART-PURIFIED-PROTEIN-NH|W|Assay of protein partially-purified from its native host],[EXP-IPI|W|Inferred from physical interaction] 10734204,10850996,15556475,27435271,30137486, Weak b0447 ECK120002859 mdlA b0448 468871 470643 forward ABC transporter family protein MdlA [COMP-HINF|W|Inferred by a human based on computational evidence] 9593292, Weak b0448 ECK120001570 mdlB b0449 470636 472417 forward ABC transporter family protein MdlB [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 9593292, Weak b0449 ECK120002080 glnK b0450 472598 472936 forward nitrogen regulatory protein PII-2 [EXP|W|Inferred from experiment] 12218023,12366843,23818625,25566239,7590157,8843440, Weak b0450 ECK120001753 amtB b0451 472966 474252 forward ammonium transporter 15568015,16563828,16563830,16564194,16740928,16910683,16953566,17012311,17040913,17098799,17119155,17263403,17434945,17453422,17668906,17998534,19761805,20639578,21134373,21775672,22631217,23010999,23546877,23650377,23667517,25483282,31765130,3542962,3888999,8843440, b0451 ECK120000984 tesB b0452 474301 475161 reverse acyl-CoA thioesterase II 17609944, b0452 ECK120002860 ybaY b0453 475379 475951 forward PF09619 family lipoprotein YbaY 15174130,21705547,32053772, b0453 ECK120002861 ybaZ b0454 475982 476371 reverse DNA base-flipping protein [EXP-IGI|W|Inferred from genetic interaction],[EXP-IDA-PART-PURIFIED-PROTEIN|W|Assay of partially-purified protein ] 18084297,19269902,20921378,25703834, Weak b0454 ECK120002469 ffs b0455 476448 476561 forward signal recognition particle 4.5S RNA 11904184,12702815,1331806,15611297,7525539,8073757,8772186,95791, b0455 ECK120001087 ybaA b0456 476672 477025 forward DUF1428 domain-containing protein YbaA b0456 ECK120002862 pdeB b0457 477067 478617 reverse c-di-GMP phosphodiesterase PdeB 29018125, b0457 ECK120002863 ylaC b0458 478781 479251 reverse putative inner membrane protein b0458 ECK120002699 maa b0459 479367 479918 reverse maltose -acetyltransferase 16321936, b0459 ECK120000432 hha b0460 480090 480308 reverse haemolysin expression-modulating protein Hha [EXP|W|Inferred from experiment] 11109097,1484495,15135405,16199570,16650431,16950844,17041043,18545668,18675805,1884997,1956303,8825785,9345762, Weak b0460 ECK120002285 tomB b0461 480334 480708 reverse Hha toxicity modulator TomB [EXP-IGI|W|Inferred from genetic interaction] 18545668, Weak b0461 ECK120001647 acrB b0462 481254 484403 reverse multidrug efflux pump RND permease AcrB 12738864,12949086,14576158,15111118,16166543,17015668,17275331,17467658,17905989,17910961,18073115,18761695,18849422,19136595,20212112,20548943,20676995,20804453,21081915,21513882,21529338,21616055,21657235,21664361,21698261,21707050,21964467,22163011,22766312,22825052,22877148,23088914,23175790,23560030,23627437,23673416,23991711,24083838,24247144,24386963,24551234,24558035,24715637,24854514,25114133,25451234,25633129,25645845,25657644,25685792,25918513,26240069,26365278,26787896,26869688,26900716,26976576,27045078,27161641,27789287,28129976,28497315,28553265,28770910,28808284,28890187,28987732,29038251,29117682,29118749,29126836,29177823,29177830,29238744,29574104,30416087,31070373,31075229,31251753,31773650,31801655,31998988,32013182,32487753,32665275,32680969,32960482,33149158,33277358, b0462 ECK120001646 acrA b0463 484426 485619 reverse multidrug efflux pump membrane fusion lipoprotein AcrA 11858709,12949086,16922505,1739728,19411330,20132445,22339851,31438868,32053772,3900282,390095,4612100,6185840,6754706,7651136, b0463 ECK120002020 acrR b0464 485761 486408 forward DNA-binding transcriptional repressor AcrR [EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 18607081,8821940, Weak b0464 ECK120002864 mscK b0465 486536 489898 forward potassium dependent, small conductance mechanosensitive channel 12505982,15657299,19132368,22790324,23842527,2480919, b0465 ECK120002390 ybaM b0466 490110 490271 reverse DUF2496 domain-containing protein YbaM [EXP-IMP|W|Inferred from mutant phenotype] 19734312, Weak b0466 ECK120000756 priC b0467 490285 490812 reverse primosomal replication protein N'' [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 1856227,8663104, Weak b0467 ECK120002396 ybaN b0468 490882 491259 forward DUF454 domain-containing inner membrane protein YbaN 19357087, b0468 ECK120000047 apt b0469 491412 491963 forward adenine phosphoribosyltransferase 1870125,187528,193369,21111048,24587082,29511080,3025682,334631,341885,348574,3524135,3527873,357906,365172,397764,410701,413544,4598216,4908785,6292052,6787390,6809533,7691799,776740,793927,827551, b0469 ECK120000239 dnaX b0470 492092 494023 forward DNA polymerase III subunit γ 6254978, b0470 ECK120000239 dnaX b0470 492092 494023 forward DNA polymerase III subunit τ 6254978, b0470 ECK120001088 ybaB b0471 494076 494405 forward putative nucleoid-associated protein YbaB b0471 ECK120000825 recR b0472 494405 495010 forward recombination mediator protein RecR [EXP-IDA|W|Inferred from direct assay],[EXP-IGI|W|Inferred from genetic interaction] 11743007,12769856,15687199,1698765,2674903,26874520,27974172,33450019,7517004,7862097,8537414,9048946,9537373, Weak b0472 ECK120000454 htpG b0473 495120 496994 forward chaperone protein HtpG 1537791,20345652,22063096,22094315,28653216,31125567,33937334,8576050, b0473 ECK120000029 adk b0474 497175 497819 forward adenylate kinase 18980321,19143839,21478347,21810404,22685395,22898007,23649926,25700573,26165596,26988127,27214237,28602083,29084520,31851990, b0474 ECK120000424 hemH b0475 498055 499017 forward ferrochelatase 7638191, b0475 ECK120001089 aes b0476 499014 499973 reverse acetylesterase b0476 ECK120001090 gsk b0477 500125 501429 forward inosine/guanosine kinase 11440147,19153081,22159740,32857952,33007252,4377732,6300032,7665468,7721718,8382990,9457797, b0477 ECK120002335 ybaL b0478 501562 503238 reverse putative transporter YbaL 31438868, b0478 ECK120002865 fsr b0479 503476 504696 reverse fosmidomycin efflux pump b0479 ECK120001049 ushA b0480 504914 506566 forward 5'-nucleotidase / UDP-sugar hydrolase 1093908,1103973,23333297,3012467,5341266,6265322,6363215,8288106, b0480 ECK120002303 ybaK b0481 506603 507082 reverse Cys-tRNA deacylase YbaK [EXP|W|Inferred from experiment],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 15886196,23185990, Weak b0481 ECK120002642 chiX b4585 507204 507287 forward small regulatory RNA ChiX [EXP-IMP|W|Inferred from mutant phenotype] 19400782,19426207,30287822,33748186, Weak b4585 ECK120002866 ybaP b0482 507286 508080 reverse TraB family protein YbaP b0482 ECK120002867 ybaQ b0483 508218 508559 forward DNA-binding transcriptional regulator YbaQ [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IPI|W|Inferred from physical interaction] 10734204,15556475,30137486, Weak b0483 ECK120002868 copA b0484 508875 511379 reverse soluble Cu chaperone [EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ] 28107647,31586033,33850135,9868784, Weak b0484 ECK120002868 copA b0484 508875 511379 reverse Cu exporting P-type ATPase [EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ] 28107647,31586033,33850135,9868784, b0484 ECK120002869 glsA b0485 511641 512573 forward glutaminase 1 23337585, b0485 ECK120002870 ybaT b0486 512576 513868 forward putative transporter YbaT 16753059,31438868, b0486 ECK120002871 cueR b0487 513993 514400 forward DNA-binding transcriptional dual regulator CueR [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 10915804,11136469,11167016,12446701,15773991, Strong b0487 ECK120002872 ybbJ b0488 514401 514859 reverse NfeD-like family protein YbbJ b0488 ECK120002873 qmcA b0489 514856 515773 reverse PHB domain-containing protein QmcA 19138386,31062059, b0489 ECK120002874 fetA b0490 515919 516596 forward putative iron ABC exporter ATP-binding subunit FetA [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 24038693,26774489,28911185,31438868, Weak b0490 ECK120002875 fetB b0491 516583 517362 forward putative iron ABC exporter membrane subunit FetB [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 24038693,26774489, Weak b0491 ECK120002876 cnoX b0492 517425 518279 reverse chaperedoxin [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 18657513,21195694,21498507,29754824, Weak b0492 ECK120002877 ybbO b0493 518340 519149 reverse NADP-dependent aldehyde reductase YbbO b0493 ECK120001496 tesA b0494 519139 519765 reverse multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 b0494 ECK120001600 ybbA b0495 519733 520419 forward putative ABC transporter ATP-binding protein YbbA 31438868, b0495 ECK120002878 ybbP b0496 520416 522830 forward putative ABC transporter membrane subunit YbbP 31438868, b0496 ECK120000840 rhsD b0497 523261 527541 forward protein RhsD [EXP-IEP|W|Inferred from expression pattern] 6086936,8808933, Weak b0497 ECK120001705 ybbC b0498 527581 527949 forward PF15631 family protein YbbC 32053772, b0498 ECK120002879 ylbH b0499 527949 528659 forward putative RHS domain-containing protein YlbH 9696756, b0499 ECK120001706 ybbD b0501 528640 529130 forward putative uncharacterized protein YbbD b0500,b0501 ECK125276502 ylbI b4632 529497 529592 forward RHS element protein YlbI b4632 ECK120002881 ylbG b0502 529645 530016 reverse putative DNA-binding transcriptional regulator YlbG b0502 ECK120001704 selU b0503 530132 531226 reverse tRNA 2-selenouridine synthase 16086848,1766878, b0503 ECK120002882 allS b0504 531295 532221 reverse DNA-binding transcriptional activator AllS b0504 ECK120002883 allA b0505 532451 532933 forward ureidoglycolate lyase b0505 ECK120002884 allR b0506 533011 533826 forward DNA-binding transcriptional repressor AllR [EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ] 10601204,12460564, Weak b0506 ECK125303723 allZ b4831 533629 533863 forward small RNA AllZ b4831 ECK120001534 gcl b0507 533916 535697 forward glyoxylate carboligase b0507 ECK120002885 hyi b0508 535710 536486 forward hydroxypyruvate isomerase 13753902, b0508 ECK120002886 glxR b0509 536586 537464 forward tartronate semialdehyde reductase 2 b0509 ECK120002888 ybbW b0511 537633 539087 forward putative allantoin transporter 22705263, b0511 ECK120002889 allB b0512 539147 540508 forward allantoinase b0512 ECK120002890 ybbY b0513 540565 541866 forward putative purine transporter 22523558,31438868, b0513 ECK120002891 glxK b0514 541888 543033 forward glycerate 2-kinase 2 b0514 ECK120002892 allE b0515 543261 544046 reverse (S)-ureidoglycine aminohydrolase 24417435, b0515 ECK120002893 allC b0516 544057 545292 reverse allantoate amidohydrolase b0516 ECK120002894 allD b0517 545314 546363 reverse ureidoglycolate dehydrogenase b0517 ECK120002895 fdrA b0518 546680 548347 forward putative oxamate carbamoyltransferase FdrA [EXP-IGI|W|Inferred from genetic interaction] 7500942, Weak b0518 ECK120002896 ylbE b4572 548357 549616 forward DUF1116 domain-containing protein YlbE b0519,b4507,b4572 ECK120002897 ylbF b0520 549627 550442 forward DUF2877 domain-containing protein YlbF b0520 ECK120002249 ybcF b0521 550439 551332 forward putative carbamate kinase 24391520, b0521 ECK120000787 purK b0522 551527 552594 reverse 5-(carboxyamino)imidazole ribonucleotide synthase b0522 ECK120000784 purE b0523 552591 553100 reverse -carboxyaminoimidazole ribonucleotide mutase b0523 ECK120002352 lpxH b0524 553218 553940 reverse UDP-2,3-diacylglucosamine diphosphatase 6345522, b0524 ECK120000749 ppiB b0525 553943 554437 reverse peptidyl-prolyl isomerase B 12135760,25845584,28752912,31951412, b0525 ECK120000191 cysS b0526 554611 555996 forward cysteine—tRNA ligase 18755841, b0526 ECK120002366 ybcI b0527 556032 556553 reverse PF04307 family inner membrane protein YbcI b0527 ECK120002418 ybcJ b0528 556661 556873 reverse putative RNA-binding protein YbcJ [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 12837795,19402753,27732863, Weak b0528 ECK120000322 folD b0529 556875 557741 reverse bifunctional methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 12391881,25448816,26531681,350870,4378935,8226914,9061797, b0529 ECK120002898 sfmA b0530 558212 558754 forward putative fimbrial protein SfmA [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825, Weak b0530 ECK120002899 sfmC b0531 558974 559666 forward putative fimbrial chaperone SfmC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825, Weak b0531 ECK120002900 sfmD b0532 559697 562300 forward putative fimbrial usher protein SfmD [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 12192075,20345943,21344461,23382825, Weak b0532 ECK120002901 sfmH b0533 562336 563319 forward putative fimbrial adhesin protein SfmH [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825, Weak b0533 ECK120002253 sfmF b0534 563330 563845 forward putative fimbrial protein SfmF [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825, Weak b0534 ECK120001091 fimZ b0535 563848 564480 reverse putative LuxR family transcriptional regulator FimZ [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 12618449,17222132, Weak b0535 ECK120002457 argU b0536 564723 564799 forward tRNA-Arg(UCU) [AS-TAS|W|Traceable author statement] 7033244, Weak b0536 ECK120000500 intD b0537 564815 565978 reverse DLP12 prophage; putative integrase b0537 ECK125276496 xisD b4633 565858 566079 reverse excisionase b4633 ECK120002902 Phantom Gene b0538 565972 566532 forward b0538 ECK120002903 exoD b0539 566098 566361 reverse DLP12 prophage; putative exonuclease ExoD b0539 ECK120026446 peaD b4508 566376 566687 forward b4508 ECK120023909 insEF3 566842 568004 forward IS3 element transposase ECK120002904 insE3 b0540 566842 567141 forward DLP12 prophage; IS3 element protein InsE b0540 ECK120002905 insF3 b0541 567138 568004 forward DLP12 prophage; IS3 element protein InsF b0541 ECK120000622 emrE b0543 568315 568647 forward DLP12 prophage; multidrug/betaine/choline efflux transporter EmrE b0543 ECK125276534 ylcJ b4733 568695 568844 forward DLP12 prophage; protein YlcJ b4733 ECK120002908 ybcK b0544 568902 570428 forward DLP12 prophage; putative recombinase YbcK b0544 ECK120002909 ybcL b0545 570893 571444 forward DLP12 prophage; periplasmic protein YbcL [COMP-HINF|W|Inferred by a human based on computational evidence] 11439028, Weak b0545 ECK120002910 ybcM b0546 571454 572251 forward DLP12 prophage; putative DNA-binding transcriptional regulator [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15556475, Weak b0546 ECK120030068 ylcH b4588 572368 572469 forward DLP12 prophage; uncharacterized protein YlcH b4588 ECK120002911 ybcN b0547 572466 572921 forward DLP12 prophage; DNA base-flipping protein b0547 ECK120002912 ninE b0548 572921 573091 forward DLP12 prophage; NinE family prophage protein b0548 ECK120002913 ybcO b0549 573084 573374 forward DLP12 prophage; putative nuclease YbcO b0549 ECK120002914 rusA b0550 573371 573733 forward DLP12 prophage; crossover junction endodeoxyribonuclease RusA b0550 ECK120016287 ylcG b4509 573730 573870 forward DLP12 prophage; uncharacterized protein YlcG b4509 ECK120002915 quuD b0551 573956 574339 forward DLP12 prophage; prophage antitermination protein Q homolog QuuD [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 23378572,8648624, Weak b0551 ECK125289860 ipeX 574367 574515 reverse small RNA IpeX 16385048, ECK120002916 insH2 b0552 574737 575717 reverse DLP12 prophage; IS transposase and trans-activator b0552 ECK120002917 essD b0554 577398 577613 forward DLP12 prophage; putative phage lysis protein [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 17914239, Weak b0554 ECK120002918 rrrD b0555 577613 578110 forward DLP12 prophage; lysozyme b0555 ECK120002919 rzpD b0556 578107 578568 forward DLP12 prophage; putative prophage endopeptidase RzpD b0556 ECK120016288 rzoD b4510 578327 578509 forward DLP12 prophage; putative prophage lysis lipoprotein RzoD 32053772, b4510 ECK120002920 borD b0557 578600 578893 reverse DLP12 prophage; prophage lipoprotein BorD 12900028, b0557 ECK120002921 ybcV b0558 579184 579594 reverse DLP12 prophage; DUF1398 domain-containing protein YbcV b0558 ECK120002922 ybcW b0559 579880 580086 forward DLP12 prophage; uncharacterized protein YbcW b0559 ECK120030069 ylcI b4589 580251 580445 reverse DLP12 prophage; DUF3950 domain-containing protein YlcI b4589 ECK120001582 nohD b0560 580834 581379 forward DLP12 prophage; putative DNA-packaging protein NohD b0560 ECK125276498 aaaD b4634 581354 581662 forward DLP12 prophage; protein AaaD b4634 ECK120002923 tfaD b0561 581534 582097 forward DLP12 prophage; putative tail fiber assembly protein TfaD b0561 ECK120002924 ybcY b0562 582152 582806 reverse DLP12 prophage; putative SAM-dependent methyltransferase YbcY b0562 ECK120002925 tfaX b0563 582875 583060 forward DLP12 prophage; protein TfaX b0563 ECK120000046 appY b0564 583681 584430 forward DLP12 prophage; DNA-binding transcriptional activator AppY [EXP|W|Inferred from experiment] 2537825,27718375,3295784,8071219, Weak b0564 ECK120000666 ompT b0565 584680 585633 reverse DLP12 prophage; omptin family outer membrane protease OmpT [EXP-IMP|W|Inferred from mutant phenotype] 15293449,29518576,29802191,9829254, Weak b0565 ECK120000262 envY b0566 586147 586908 reverse DNA-binding transcriptional activator EnvY [EXP|W|Inferred from experiment] 2536924, Weak b0566 ECK120002300 ybcH b0567 587091 587981 reverse putative exopolysaccharide secretion system auxiliary component [COMP-HINF-IGC|W|Inferred from genomic context] 34903052, Weak b0567 ECK120001679 nfrA b0568 587982 590954 reverse exopolysaccharide secretion system outer membrane protein NfrA [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 2670887,34903052, Weak b0568 ECK120001678 nfrB b0569 590941 593178 reverse cyclic di-3',5'-guanylate-activated glycosyltransferase [EXP-IMP|W|Inferred from mutant phenotype] 19011026,2670887, Weak b0569 ECK120002926 cusS b0570 593328 594770 reverse sensor histidine kinase CusS b0570 ECK120002927 cusR b0571 594760 595443 reverse DNA-binding transcriptional activator CusR [EXP|W|Inferred from experiment] 11514505,30530842, Weak b0571 ECK120002928 cusC b0572 595600 596973 forward copper/silver export system outer membrane channel 31586033,32053772, b0572 ECK120002929 cusF b0573 597131 597463 forward copper/silver export system periplasmic binding protein 24298878,25940871, b0573 ECK120002930 cusB b0574 597479 598702 forward copper/silver export system membrane fusion protein 12829274,23988152,25940871,28636907,30456313,31465444,31887125, b0574 ECK120002235 cusA b0575 598714 601857 forward copper/silver export system RND permease 12829274,16820466,21221942, b0575 ECK120000700 pheP b0576 601959 603335 forward phenylalanine:H symporter PheP b0576 ECK120002931 ybdG b0577 603416 604663 reverse miniconductance mechanosensitive channel YbdG b0577 ECK120002564 nfsB b0578 604771 605424 reverse NAD(P)H-dependent nitroreductase NfsB 14500391,19580253,19665450,20083491,22173483,23698620,24807676,25917861,29740005,29790650,30067333,30414836,30630092,31109333,31403283,31581475,31906851,32596098,32798330,33007545,6339681,6387400, b0578 ECK120002932 ybdF b0579 605518 605886 reverse PF04237 family protein YbdF b0579 ECK120002933 ybdJ b0580 605951 606199 reverse DUF1158 domain-containing protein YbdJ b0580 ECK120002934 ybdK b0581 606265 607383 reverse putative glutamate—cysteine ligase 2 b0581 ECK125328227 sokE b4835 607733 607792 reverse small RNA SokE b4835 ECK125240990 b4700 b4700 607734 607792 forward ECK120002654 hokE b4415 607836 607988 forward protein HokE [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10361310,17065468, Weak b4415 ECK120002935 insL2 b0582 608065 609177 forward IS186/IS421 transposase b0582 ECK120000256 entD b0583 609459 610079 reverse phosphopantetheinyl transferase EntD b0583 ECK120000287 fepA b0584 610254 612494 reverse ferric enterobactin outer membrane transporter 10998164,12779236,140161,15150246,19432807,2139651,27935943,2942532,32098871,34544275,4946186,7543,9852016, b0584 ECK120000293 fes b0585 612737 613939 forward ferric enterobactin esterase 131121,132428,23098193,23908556,24516157,25420677,2958600,4337557,4568262,6260579, b0585 ECK120016289 ybdZ b4511 613942 614160 forward enterobactin biosynthesis protein YbdZ [EXP-IMP|W|Inferred from mutant phenotype] 20845982,21890635,24975514, Weak b4511 ECK120000258 entF b0586 614157 618038 forward apo-serine activating enzyme [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10688898,17606920,24975514,9485415, Strong b0586 ECK120000291 fepE b0587 618254 619387 forward polysaccharide co-polymerase family protein FepE 19058968, b0587 ECK120000289 fepC b0588 619384 620199 reverse ferric enterobactin ABC transporter ATP binding subunit b0588 ECK120000292 fepG b0589 620196 621188 reverse ferric enterobactin ABC transporter membrane subunit FepG 1479347, b0589 ECK120000290 fepD b0590 621185 622189 reverse ferric enterobactin ABC transporter membrane subunit FebD 1479347, b0590 ECK120001092 entS b0591 622300 623550 forward enterobactin exporter EntS b0591 ECK120000288 fepB b0592 623554 624510 reverse ferric enterobactin ABC transporter periplasmic binding protein 21194366, b0592 ECK120000255 entC b0593 624885 626060 forward isochorismate synthase EntC 16605270, b0593 ECK120000257 entE b0594 626070 627680 forward 2,3-dihydroxybenzoate-AMP ligase b0594 ECK120000254 entB b0595 627694 628551 forward enterobactin synthase component B [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 126224,17606920,19119850,19699210,23380376,9485415, Strong b0595 ECK120000253 entA b0596 628551 629297 forward 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase b0596 ECK120001093 entH b0597 629300 629713 forward proofreading thioesterase in enterobactin biosynthesis b0597 ECK120000163 cstA b0598 629894 631999 forward pyruvate transporter CstA b0598 ECK120016290 ybdD b4512 632182 632379 forward PF04328 family protein YbdD b4512 ECK120002357 hcxA b0599 632389 633477 reverse hydroxycarboxylate dehydrogenase A b0599 ECK120002936 ybdL b0600 633586 634746 forward methionine transaminase b0600 ECK120002937 ybdM b0601 634747 635376 reverse ParB-like nuclease domain-containing protein YbdM 24391520, b0601 ECK120002938 ybdN b0602 635349 636569 reverse putative PAPS reductase/DUF3440 domain-containing protein YbdN b0602 ECK120002939 ybdO b0603 636716 637618 reverse putative LysR family DNA-binding transcriptional regulator YbdO [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15556475,26789284, Weak b0603 ECK120002940 dsbG b0604 637827 638573 reverse protein sulfenic acid reductase and chaperone DsbG b0604 ECK120001351 ahpC b0605 638945 639508 forward alkyl hydroperoxide reductase, AhpC component 12589799,15672380,1592833,17906139,18315945,19138658,19223646,25193562, b0605 ECK120001352 ahpF b0606 639753 641318 forward alkyl hydroperoxide reductase, AhpF component 1592833,23122414,24952731,31281172, b0606 ECK120002941 uspG b0607 641439 641867 reverse universal stress protein G b0607 ECK120002942 ybdR b0608 642088 643326 forward putative Zn-dependent alcohol dehydrogenase YbdR b0608 ECK125276513 yldA b4734 643330 643419 reverse protein YldA b4734 ECK120002943 Phantom Gene b0609 643407 643868 forward b0609 ECK120002944 rnk b0610 643557 643967 reverse nucleoside diphosphate kinase regulator [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 18760284,8596442, Weak b0610 ECK120000847 rna b0611 644197 645003 reverse RNase I b0611 ECK120002945 citT b0612 645117 646580 reverse citrate:succinate antiporter 2999088, b0612 ECK120002946 citG b0613 646631 647509 reverse triphosphoribosyl-dephospho-CoA synthase b0613 ECK120002947 citX b0614 647484 648035 reverse apo-citrate lyase phosphoribosyl-dephospho-CoA transferase 11052676, b0614 ECK120002948 citF b0615 648039 649571 reverse citrate lyase α subunit b0615 ECK120002949 citE b0616 649582 650490 reverse citrate lyase β subunit b0616 ECK120002950 citD b0617 650487 650783 reverse citrate lyase acyl carrier protein b0617 ECK120002951 citC b0618 650798 651856 reverse citrate lyase synthetase b0618 ECK120002952 dpiB b0619 652235 653893 forward sensor histidine kinase DpiB 12853150,15522865, b0619 ECK120002953 dpiA b0620 653862 654542 forward DNA-binding transcriptional dual regulator DpiA b0620 ECK120002954 dcuC b0621 654583 655968 reverse anaerobic C4-dicarboxylate transporter DcuC 1512189, b0621 ECK120002073 pagP b0622 656557 657117 forward Lipid A palmitoyltransferase 10373459,15126461,18641391,27050393,31326704, b0622 ECK120002072 cspE b0623 657292 657501 forward transcription antiterminator and regulator of RNA stability CspE 14712721,21926233,22026739,23760898,25579583,26500258,27091548,32542384,32753505, b0623 ECK120002096 crcB b0624 657555 657938 reverse F channel b0624 ECK120002095 ybeM b4581 658031 658818 forward deamidated glutathione amidase, N-terminal fragment b0625,b0626,b4581 ECK120001278 tatE b0627 658947 659150 forward twin arginine protein translocation system - TatE protein b0627 ECK120001279 lipA b0628 659251 660216 reverse lipoyl synthase 12125819,12234497,1577793,15911379,1832150,20707605,24901788,28068366,29051382,366070,4889470, b0628 ECK120001542 ybeF b0629 660425 661378 reverse putative DNA-binding transcriptional regulator YbeF [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b0629 ECK120001540 lipB b0630 661637 662278 reverse lipoyl(octanoyl) transferase 11106496,1832150,19684135,25303731,366070, b0630 ECK120001541 ybeD b0631 662379 662642 reverse DUF493 domain-containing protein YbeD b0631 ECK120000195 dacA b0632 662752 663963 reverse D-alanyl-D-alanine carboxypeptidase DacA 3279397, b0632 ECK120000845 rlpA b0633 664102 665190 reverse rare lipoprotein RlpA 19684127,26305949,32053772, b0633 ECK120000600 mrdB b0634 665201 666313 reverse peptidoglycan glycosyltransferase MrdB 11418550,1885519,2066344,2114032,2254246,3017915,3894330,6243629,6451612,8407846,9573213, b0634 ECK120000599 mrdA b0635 666316 668217 reverse peptidoglycan DD-transpeptidase MrdA 10383966,10969046,11014799,11051618,11099493,11102351,11254985,11418550,11766406,12107141,12709336,12723972,15853883,16619114,16751270,17188233,17513478,17581120,17993535,18390656,1885519,19078962,1925032,19346310,201607,2066344,2254246,23301723,24550500,3009484,30496417,30963998,3326629,3894330,6180685,6300030,6451612,8407846,8760906,9723920, b0635 ECK120001229 rlmH b0636 668248 668715 reverse 23S rRNA mΨ1915 methyltransferase 22411911,30314655,31525988, b0636 ECK120001230 rsfS b0637 668719 669036 reverse ribosomal silencing factor RsfS [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 22829778,23228329,33639093, Weak b0637 ECK120002956 cobC b0638 669296 669907 reverse putative adenosylcobalamin phosphatase/α-ribazole phosphatase b0638 ECK120002957 nadD b0639 669931 670572 reverse nicotinate-nucleotide adenylyltransferase 23289308,29082479, b0639 ECK120001378 holA b0640 670574 671605 reverse DNA polymerase III subunit δ 8505303, b0640 ECK120000846 lptE b0641 671605 672186 reverse lipopolysaccharide assembly protein LptE [EXP-IMP|W|Inferred from mutant phenotype] 15126489,16861298,32053772,34070637, Weak b0641 ECK120000525 leuS b0642 672201 674783 reverse leucine—tRNA ligase 18845434,22292813,7629064, b0642 ECK120002400 ybeL b0643 675018 675500 forward DUF1451 domain-containing protein YbeL b0643 ECK120002958 ybeQ b0644 675570 676547 reverse Sel1 repeat-containing protein YbeQ b0644 ECK120002959 ybeR b0645 676711 677418 forward DUF1266 domain-containing protein YbeR 24391520, b0645 ECK120002960 djlB b0646 677415 678842 forward J domain-containing protein DjlB [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10574456, Weak b0646 ECK120002961 ybeT b0647 678852 679406 reverse Sel1 repeat-containing protein YbeT 24391520, b0647 ECK120002962 ybeU b0648 679508 680215 forward DUF1266 domain-containing protein YbeU b0648 ECK120002963 djlC b0649 680212 681663 forward co-chaperone DjlC b0649 ECK120002964 hscC b0650 681723 683393 reverse chaperone protein HscC [EXP|W|Inferred from experiment] Weak b0650 ECK120002965 rihA b0651 683477 684412 reverse pyrimidine-specific ribonucleoside hydrolase RihA b0651 ECK120002351 gltL b0652 684530 685255 reverse glutamate/aspartate ABC transporter ATP binding subunit b0652 ECK120002350 gltK b0653 685255 685929 reverse glutamate/aspartate ABC transporter membrane subunit GltK b0653 ECK120002349 gltJ b0654 685929 686669 reverse glutamate/aspartate ABC transporter membrane subunit GltJ b0654 ECK120002643 sroC b4763 686681 686843 reverse small regulatory RNA SroC [EXP-IMP|W|Inferred from mutant phenotype] 25916829,26469694,29992897,34093460, Weak b4763 ECK120002966 gltI b0655 686839 687747 reverse glutamate/aspartate ABC transporter periplasmic binding protein b0655 ECK120002967 insH3 b0656 687997 688977 reverse IS transposase and trans-activator b0656 ECK120000164 lnt b0657 689343 690881 reverse apolipoprotein -acyltransferase 25471278,29573991,3525566, b0657 ECK120002968 ybeX b0658 690906 691784 reverse CorC-HlyC family protein YbeX 1779764, b0658 ECK120002969 ybeY b0659 691874 692341 reverse endoribonuclease YbeY [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 19181801,23273979,23638028,26185078,27834201,33503254, Weak b0659 ECK120002970 ybeZ b0660 692338 693378 reverse PhoH-like protein b0660 ECK120002971 miaB b0661 693531 694955 reverse isopentenyl-adenosine A37 tRNA methylthiolase 20489182,22081392,22092591, b0661 ECK120002972 ubiF b0662 695101 696276 forward 3-demethoxyubiquinol 3-hydroxylase 12753928,16624818,365223, b0662 ECK120002473 glnX b0664 696430 696504 reverse tRNA-Gln(CUG) [AS-TAS|W|Traceable author statement] 7033244, Weak b0664 ECK120002471 glnV b0665 696542 696616 reverse tRNA-Gln(CUG) [AS-TAS|W|Traceable author statement] 7033244, Weak b0665 ECK120002501 metU b0666 696664 696740 reverse tRNA-Met(CAU) [AS-TAS|W|Traceable author statement] 7033244, Weak b0666 ECK120002472 glnW b0668 696756 696830 reverse tRNA-Gln(UUG) [AS-TAS|W|Traceable author statement] 7033244, Weak b0668 ECK120002470 glnU b0670 696865 696939 reverse tRNA-Gln(UUG) [AS-TAS|W|Traceable author statement] 7033244, Weak b0670 ECK120002494 leuW b0672 696963 697047 reverse tRNA-Leu(UAG) [AS-TAS|W|Traceable author statement] 7033244, Weak b0672 ECK120002500 metT b0673 697057 697133 reverse tRNA-Met(CAU) [AS-TAS|W|Traceable author statement] 7033244, Weak b0673 ECK120000088 asnB b0674 697513 699177 reverse asparagine synthetase B 1973930, b0674 ECK120000627 umpH b0675 699574 700326 reverse UMP phosphatase b0675 ECK120000629 nagC b0676 700374 701594 reverse DNA-binding transcriptional dual regulator NagC [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 11139621,15066032,15534208,15743943,17238917,1766379,1848637,2190615,2668691,7545108, Weak b0676 ECK120000625 nagA b0677 701603 702751 reverse -acetylglucosamine-6-phosphate deacetylase b0677 ECK120000626 nagB b0678 702811 703611 reverse glucosamine-6-phosphate deaminase 23082955,24976172,29229699, b0678 ECK120000628 nagE b0679 703944 705890 forward N-acetylglucosamine-specific PTS enzyme IIABC component b0679 ECK120000383 glnS b0680 706093 707757 forward glutamine—tRNA ligase 27939931,34608152, b0680 ECK125302574 chiZ b4808 708236 708333 forward small regulatory RNA ChiZ [EXP-IMP|W|Inferred from mutant phenotype] 33460557, Weak b4808 ECK120002973 chiP b0681 708334 709740 forward chitooligosaccharide outer membrane channel 16857666,22797760,28972167,29906877, b0681 ECK120002974 chiQ b0682 709790 710116 forward lipoprotein ChiQ b0682 ECK120000352 fur b0683 710200 710646 reverse DNA-binding transcriptional dual regulator Fur 1868094,2015825,2823881,2993806,7026976, b0683 ECK120029856 uof b4637 710639 710725 reverse RyhB-regulated leader peptide [EXP-IDA|W|Inferred from direct assay] 17268550, Weak b4637 ECK120000312 fldA b0684 710935 711465 reverse flavodoxin 1 [EXP|W|Inferred from experiment] 11493691,24016774,4927832,9839946, Weak b0684 ECK120001709 ybfE b0685 711605 711898 reverse ribbon-helix-helix domain-containing protein YbfE b0685 ECK120001710 ybfF b0686 712038 712802 reverse esterase [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 15808744, Weak b0686 ECK120002086 seqA b0687 712987 713532 forward negative modulator of initiation of replication [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 10394913,10572297,10931356,10947847,11004192,11972788,12106913,12479794,12742018,12944412,14643657,14739988,15009887,16041320,16644499,17464080,17578452,18339941,18590762,18835566,19371375,19401329,19432804,20118257,20640526,20875449,21659325,23149570,23632166,23990792,25333813,7553853,8631765,8930912,8981994,9379896,9426127,9736699, Weak b0687 ECK120002045 pgm b0688 713558 715198 forward phosphoglucomutase 32808719, b0688 ECK120002975 ybfP b0689 715412 715906 forward lipoprotein YbfP 32053772, b0689 ECK120001712 ybfG b0691 715947 716597 reverse PF10964 domain-containing protein YbfG b0690,b0691 ECK125276497 ybfI b4636 716721 716870 reverse b4636 ECK120000744 potE b0692 716946 718265 reverse putrescine transporter PotE 10964926,14643892,21796432,2249996,3005244,31438868,4598012, b0692 ECK120000953 speF b0693 718262 720460 reverse inducible ornithine decarboxylase 14982633,16747177,22138596,22812515,25307558,3897202,6353148, b0693 ECK120030070 ybfK b4590 720583 720840 forward b4590 ECK125288180 speFL b4803 720718 720822 reverse leader peptide SpeFL [EXP-IMP|W|Inferred from mutant phenotype] 32094585, Weak b4803 ECK120000510 kdpE b0694 721056 721733 reverse DNA-binding transcriptional activator KdpE [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 1482126,1532388,2157156,7699720,8098993, Weak b0694 ECK120000509 kdpD b0695 721730 724414 reverse sensor histidine kinase KdpD b0695 ECK120000508 kdpC b0696 724407 724979 reverse K transporting P-type ATPase subunit KdpC 11248697,16953591,7896809,9858692, b0696 ECK120000507 kdpB b0697 724988 727036 reverse K transporting P-type ATPase subunit KdpB 15071553,15078102,15364580,15379567,16354672, b0697 ECK120000506 kdpA b0698 727059 728732 reverse K transporting P-type ATPase subunit KdpA 10920013,11106663,11344160,15292155, b0698 ECK120016291 kdpF b4513 728732 728821 reverse K transporting P-type ATPase subunit KdpF 10608856,9789555, b4513 ECK120001475 ybfA b0699 729134 729340 forward DUF2517 domain-containing protein YbfA b0699 ECK120000839 rhsC b0700 729583 733776 forward rhs element protein RhsC 6086936, b0700 ECK120004454 Phantom Gene b0701 733370 733591 forward b0701 ECK120001476 ybfB b0702 733776 734102 forward uncharacterized protein YbfB b0702 ECK120002976 ybfO b0703 734220 735653 forward RHS repeats-containing protein YbfO b0703 ECK120001477 ybfC b0704 735650 736219 forward uncharacterized protein YbfC b0704 ECK120016292 ybfQ b4514 736445 736699 forward inactive transposase YbfQ b4514 ECK120002977 ybfL b0705 736900 737961 forward putative transposase YbfL b0705 ECK120001478 ybfD b0706 738092 738853 forward H repeat-associated putative transposase YbfD 8387990, b0706 ECK120001094 ybgA b0707 739001 739510 forward DUF1722 domain-containing protein YbgA b0707 ECK120000727 phr b0708 739507 740925 forward deoxyribodipyrimidine photolyase 10049308,10606505,11457111,11463661,12169694,1390627,1552897,15568802,15819881,16169906,1643047,16816385,16898706,16964985,1699932,1716150,1731935,17696363,17696385,17703066,18086248,18652481,18973361,19292445,1944393,1958664,1986272,1988061,19954157,20133751,2059637,21804035,2200510,2200511,2200512,2211728,22533849,2254263,23331252,23882072,23882080,2405908,24803991,25000823,2509902,25152314,25839748,26065359,26393415,26852903,2689865,2689866,27337655,27493513,28128222,2823069,2827744,3048382,31134233,3311150,3313446,3322390,3539940,3539941,3545286,3547334,369954,3893538,6087879,6390436,7604259,7604260,7669779,7899506,7918492,8343500,8486719,8515468,8519744,8672500, b0708 ECK120002978 dtpD b0709 741075 742556 reverse dipeptide:H symporter DtpD 27916534,31438868, b0709 ECK120002979 ybgI b0710 742827 743570 forward radiation resistance protein YbgI 18824089, b0710 ECK120002980 pxpB b0711 743593 744249 forward 5-oxoprolinase component B b0711 ECK120002981 pxpC b0712 744243 745175 forward 5-oxoprolinase component C b0712 ECK120002982 pxpA b0713 745165 745899 forward 5-oxoprolinase component A b0713 ECK120002983 nei b0714 745935 746726 forward endonuclease VIII 10515930,10637328,10833024,10862773,11711552,11951664,12434002,14734554,15272182,15944451,16201966,30617079,31784740,9171430,9461450, b0714 ECK120002984 abrB b0715 746723 747769 reverse putative regulator b0715 ECK120002985 ybgO b0716 747921 748982 reverse putative fimbrial protein YbgO [COMP-AINF|W|Inferred computationally without human oversight],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 12192075,20345943,21344461,23382825, Weak b0716 ECK120002986 ybgP b0717 748979 749707 reverse putative fimbrial chaperone YbgP [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 12192075,20345943, Weak b0717 ECK120002987 ybgQ b0718 749722 752169 reverse putative fimbrial usher protein YbgQ [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 20345943,21344461,23382825, Weak b0718 ECK120002227 ybgD b0719 752229 752795 reverse putative fimbrial protein YbgD [COMP-HINF|W|Inferred by a human based on computational evidence] 20345943,21344461,23382825,24391520, Weak b0719 ECK120000395 gltA b0720 753185 754468 reverse citrate synthase b0720 ECK125286398 ybgV b4768 754658 754690 reverse protein YbgV b4768 ECK125276522 ybgU b4735 754674 754781 reverse protein YbgU b4735 ECK120000922 sdhC b0721 755177 755566 forward succinate:quinone oxidoreductase, membrane protein SdhC b0721 ECK120000923 sdhD b0722 755560 755907 forward succinate:quinone oxidoreductase, membrane protein SdhD b0722 ECK120000920 sdhA b0723 755907 757673 forward succinate:quinone oxidoreductase, FAD binding protein 29610278,2991245,6383359, b0723 ECK120000921 sdhB b0724 757689 758405 forward succinate:quinone oxidoreductase, iron-sulfur cluster binding protein 2991245,6388571, b0724 ECK120002988 b0725 b0725 758464 758724 forward ECK120000968 sucA b0726 758706 761507 forward subunit of E1(0) component of 2-oxoglutarate dehydrogenase b0726 ECK120000969 sucB b0727 761522 762739 forward dihydrolipoyltranssuccinylase 6376124, b0727 ECK120000970 sucC b0728 763014 764180 forward succinyl-CoA synthetase subunit β 8514803, b0728 ECK120000971 sucD b0729 764180 765049 forward succinyl-CoA synthetase subunit α 1577794,7783627, b0729 ECK125276535 sdhX b4764 765050 765150 forward small regulatory RNA SdhX [EXP-IMP|W|Inferred from mutant phenotype] 18467773,30541135,30591570, Weak b4764 ECK120001095 mngR b0730 765153 765875 reverse DNA-binding transcriptional repressor MngR 7805834, b0730 ECK120002432 mngA b0731 765984 767960 forward 2--α-mannosyl-D-glycerate specific PTS enzyme II b0731 ECK120002433 mngB b0732 767978 770611 forward α-mannosidase b0732 ECK120000168 cydA b0733 771458 773026 forward cytochrome -I subunit 1 15475358,15728392,1851043,18597483,19254926,26335199,30442809,32061652, b0733 ECK120000169 cydB b0734 773042 774181 forward cytochrome -I subunit 2 1328158,26100898,31723136,6376497, b0734 ECK120016293 cydX b4515 774196 774309 forward cytochrome -I accessory subunit CydX 34070637, b4515 ECK120002258 ybgE b0735 774309 774602 forward PF09600 family protein YbgE 23749980, b0735 ECK120001096 ybgC b0736 774752 775156 forward esterase/thioesterase [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 15808744,24391520, Weak b0736 ECK120000999 tolQ b0737 775153 775845 forward Tol-Pal system protein TolQ 15205446,33640981,8119930, b0737 ECK120001000 tolR b0738 775849 776277 forward Tol-Pal system protein TolR 19075020,3003021,3294803,33640981, b0738 ECK120000996 tolA b0739 776342 777607 forward Tol-Pal system protein TolA 11099384,11418549,11851406,12679333,16855227,19306883,33640981,8416897,9171417,9335297,9466263,9680221, b0739 ECK120000997 tolB b0740 777740 779032 forward Tol-Pal system periplasmic protein TolB 16855227,16894158,17012383,1704440,23812713,2687247,32094588,9466263, b0740 ECK120000677 pal b0741 779067 779588 forward peptidoglycan-associated outer membrane lipoprotein Pal 14731286,16855227,32053772,33577754,3545827, b0741 ECK120002402 cpoB b0742 779598 780389 forward cell division coordinator CpoB [EXP-IPI|W|Inferred from physical interaction],[EXP-IGI|W|Inferred from genetic interaction],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 11994151,25951518,30233559, Strong b0742 ECK120002497 lysT b0743 780554 780629 forward tRNA-Lys(UUU) [AS-TAS|W|Traceable author statement] 15558052,7033244, Weak b0743 ECK120002551 valT b0744 780765 780840 forward tRNA-Val(UAC) [AS-TAS|W|Traceable author statement] 7033244, Weak b0744 ECK120002499 lysW b0745 780843 780918 forward tRNA-Lys(UUU) [AS-TAS|W|Traceable author statement] 15558052,7033244, Weak b0745 ECK120002989 valZ b0746 781068 781143 forward tRNA-Val(UAC) [AS-TAS|W|Traceable author statement] 7033244, Weak b0746 ECK120002990 lysY b0747 781147 781222 forward tRNA-Lys(UUU) [AS-TAS|W|Traceable author statement] 15558052,7033244, Weak b0747 ECK120002991 lysZ b0748 781369 781444 forward tRNA-Lys(UUU) [AS-TAS|W|Traceable author statement] 15558052,7033244, Weak b0748 ECK120002992 lysQ b0749 781577 781652 forward tRNA-Lys(UUU) [AS-TAS|W|Traceable author statement] 15558052,7033244, Weak b0749 ECK120000623 nadA b0750 782085 783128 forward quinolinate synthase b0750 ECK120001643 pnuC b0751 783166 783885 forward nicotinamide riboside transporter 29474058, b0751 ECK120002993 zitB b0752 783882 784823 reverse Zn exporter b0752 ECK120002994 ybgS b0753 784937 785317 reverse PF13985 family protein YbgS 20188588,24391520, b0753 ECK120000075 aroG b0754 785633 786685 forward 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive 2903857, b0754 ECK120001642 gpmA b0755 786843 787595 reverse 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase b0755 ECK120001641 galM b0756 787797 788837 reverse galactose-1-epimerase b0756 ECK120000356 galK b0757 788831 789979 reverse galactokinase 12816414,13914787,15239057,15975511,21445255,3158881,8382990, b0757 ECK120000359 galT b0758 789983 791029 reverse galactose-1-phosphate uridylyltransferase b0758 ECK120000355 galE b0759 791039 792055 reverse UDP-glucose 4-epimerase 10329648,1107041,11437350,11989664,9119006, b0759 ECK120001620 modF b0760 792316 793788 reverse ABC family protein ModF 11421278,18634750,8550508, b0760 ECK120002995 modE b0761 793856 794644 reverse DNA-binding transcriptional dual regulator ModE b0761 ECK120002996 acrZ b0762 794773 794922 forward multidrug efflux pump accessory protein AcrZ [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IPI|W|Inferred from physical interaction] 19734312,23010927, Weak b0762 ECK120002283 modA b0763 795089 795862 forward molybdate ABC transporter periplasmic binding protein 15315443,21861186,7665460, b0763 ECK120000002 modB b0764 795862 796551 forward molybdate ABC transporter membrane subunit b0764 ECK120000148 modC b0765 796554 797612 forward molybdate ABC transporter ATP binding subunit 31438868, b0765 ECK120001217 ybhA b0766 797613 798431 reverse pyridoxal phosphate/fructose-1,6-bisphosphate phosphatase b0766 ECK120002997 pgl b0767 798586 799581 forward 6-phosphogluconolactonase b0767 ECK120002998 ybhD b0768 799622 800575 reverse putative DNA-binding transcriptional regulator YbhD [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b0768 ECK120002999 ybhH b0769 800759 801811 forward putative isomerase YbhH 21695201, b0769 ECK120003000 ybhI b0770 801887 803320 forward putative tricarboxylate transporter 14526028,31438868, b0770 ECK120003001 ybhJ b0771 803503 805764 forward putative hydratase YbhJ b0771 ECK120002414 ybhC b0772 805998 807281 reverse outer membrane lipoprotein YbhC 23228329,32053772, b0772 ECK120001216 ybhB b0773 807433 807909 reverse putative kinase inhibitor [COMP-HINF|W|Inferred by a human based on computational evidence] 11439028, Weak b0773 ECK120000113 bioA b0774 807968 809257 reverse adenosylmethionine-8-amino-7-oxononanoate aminotransferase b0774 ECK120000114 bioB b0775 809344 810384 forward biotin synthase b0775 ECK120000117 bioF b0776 810381 811535 forward 8-amino-7-oxononanoate synthase b0776 ECK120000115 bioC b0777 811522 812277 forward malonyl-acyl carrier protein methyltransferase b0777 ECK120000116 bioD b0778 812270 812947 forward dethiobiotin synthetase b0778 ECK120030071 ybhU b4591 813114 813251 reverse b4591 ECK120001051 uvrB b0779 813526 815547 forward UvrABC excision nuclease subunit B 25049088, b0779 ECK120003002 ybhK b0780 815739 816647 reverse putative transferase YbhK b0780 ECK120001543 moaA b0781 817044 818033 forward GTP 3',8'-cyclase 137786,1906967,2182384,23913318,2656653,28323419,2956990,30097104,3035339,3525161,3881754,3886012,3888958,398694,4576401,4579877,4941570,5246560,6315066,6363588,6370312,6460021,6757667,6991254,7012121,7026535,7031034,772165, b0781 ECK120001544 moaB b0782 818055 818567 forward protein MoaB b0782 ECK120001609 moaC b0783 818570 819055 forward cyclic pyranopterin monophosphate synthase b0783 ECK120001545 moaD b0784 819048 819293 forward molybdopterin synthase sulfur carrier subunit 2656653, b0784 ECK120001546 moaE b0785 819295 819747 forward molybdopterin synthase catalytic subunit b0785 ECK120003003 ybhL b0786 819884 820588 forward Bax1-I family protein YbhL b0786 ECK120003004 ybhM b0787 820793 821506 forward Bax1-I family protein YbhM b0787 ECK120003005 ybhN b0788 821542 822498 reverse PF03706 family inner membrane protein YbhN 31438868, b0788 ECK120003006 clsB b0789 822498 823739 reverse cardiolipin synthase B 28815570,31235517,33833055, b0789 ECK120003007 ybhP b0790 823736 824497 reverse endonuclease/exonuclease/phosphatase domain-containing protein YbhP b0790 ECK120003008 ybhQ b0791 824630 825040 forward inner membrane protein YbhQ b0791 ECK120003009 ybhR b0792 825002 826108 reverse ABC exporter membrane subunit YbhR 30578262,31438868, b0792 ECK120003010 ybhS b0793 826119 827252 reverse ABC exporter membrane subunit YbhS 31438868, b0793 ECK120003011 ybhF b0794 827245 828981 reverse ABC exporter ATP binding subunit YbhF 31438868, b0794 ECK120003012 ybhG b0795 828974 829972 reverse HlyD_D23 family protein YbhG 31438868, b0795 ECK120002268 cecR b0796 829972 830643 reverse DNA-binding transcriptional dual regulator CecR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IDA-UNPURIFIED-PROTEIN-NH|W|Assay of unpurified protein expressed in its native host],[EXP-IEP|W|Inferred from expression pattern],[EXP-IPI|W|Inferred from physical interaction] 10734204,15556475,27112147,30137486,30578262, Weak b0796 ECK120001213 rhlE b0797 830872 832236 forward ATP-dependent RNA helicase RhlE 22328678,27112147, b0797 ECK120001531 ybiA b0798 832468 832950 reverse -glycosidase YbiA b0798 ECK120001326 dinG b0799 833070 835220 forward ATP-dependent DNA helicase DinG 11333217,1629168, b0799 ECK120001532 ybiB b0800 835248 836210 forward nonspecific DNA-binding protein YbiB b0800 ECK120001533 hcxB b0801 836351 837436 forward hydroxycarboxylate dehydrogenase B b0801 ECK125303724 zbiJ b4814 837435 837531 reverse small regulatory RNA ZbiJ [EXP-IDA|W|Inferred from direct assay] 33622723,34093460, Weak b4814 ECK125286409 ybiE b4769 837503 837562 forward protein YbiE 30837344, b4769 ECK120002280 ybiJ b0802 837665 837925 reverse DUF1471 domain-containing protein YbiJ 24391520, b0802 ECK120002279 ybiI b0803 838190 838456 reverse zinc finger domain-containing protein YbiI b0803 ECK120003013 ybiX b0804 838530 839207 reverse PKHD-type hydroxylase YbiX b0804 ECK120003014 fiu b0805 839249 841531 reverse iron catecholate outer membrane transporter Fiu 18318713,18502859,19214756,1960119,3323834,6353165,9210292,9450313, b0805 ECK120003015 mcbA b0806 841796 842056 reverse DUF1471 domain-containing protein McbA [EXP-IMP|W|Inferred from mutant phenotype] 18309357, Weak b0806 ECK120003016 rlmF b0807 842332 843258 forward 23S rRNA mA1618 methyltransferase b0807 ECK120003017 ybiO b0808 843255 845480 reverse moderate conductance mechanosensitive channel YbiO b0808 ECK120000382 glnQ b0809 845741 846463 reverse L-glutamine ABC transporter ATP binding subunit b0809 ECK120000381 glnP b0810 846460 847119 reverse L-glutamine ABC transporter membrane subunit 31438868, b0810 ECK120000379 glnH b0811 847258 848004 reverse L-glutamine ABC transporter periplasmic binding protein 12935905,1422149,17098801,19883597,20141110,22206385,9090131, b0811 ECK120001381 dps b0812 848408 848911 reverse DNA protection during starvation protein 18452510, b0812 ECK120002036 rhtA b0813 849210 850097 reverse L-threonine/L-homoserine exporter 11514505,12648727,17025177,18594129,21620993,26363557,28911185,31438868, b0813 ECK125276532 yliM b4736 850332 850397 forward protein YliM b4736 ECK120002021 ompX b0814 850450 850965 forward outer membrane protein X 18512961,20820947,20922370,24077225,24265768,25430058,30289706,30633426,30848905,31374213,34097860, b0814 ECK120003018 opgE b0815 851014 852597 reverse phosphoethanolamine transferase OpgE 10779706,28593831, b0815 ECK120003019 yliL b0816 852671 852940 forward b0816 ECK120002592 rybA b4416 852725 853064 reverse small RNA RybA [EXP-IMP|W|Inferred from mutant phenotype] 11445539,22336764,26076491, Weak b4416 ECK125140755 mntS b4705 852869 852997 reverse small protein MntS [EXP-IMP|W|Inferred from mutant phenotype] 25774656,26076491,29111488, Weak b4705 ECK120003020 mntR b0817 853183 853650 forward DNA-binding transcriptional dual regulator MntR b0817 ECK120003021 ybiR b0818 853647 854765 forward putative transporter YbiR 15466053,31438868, b0818 ECK120003022 ldtB b0819 854824 855744 reverse L,D-transpeptidase LdtB 12192075,31743648, b0819 ECK120003023 ybiT b0820 855963 857555 forward putative ATP-binding protein YbiT 11916677,15466053,28911185, b0820 ECK120003024 ybiU b0821 857796 859061 reverse DUF1479 domain-containing protein YbiU b0821 ECK120003025 ybiV b0822 859213 860028 reverse sugar phosphatase YbiV b0822 ECK120003026 ybiW b0823 860174 862606 reverse putative pyruvate formate lyase 24391520, b0823 ECK120003027 ybiY b0824 862612 863511 reverse putative pyruvate formate-lyase activating enzyme YbiY b0824 ECK120003028 fsaA b0825 863642 864304 forward fructose-6-phosphate aldolase 1 b0825 ECK120000150 moeB b0826 864380 865129 reverse molybdopterin-synthase adenylyltransferase b0826 ECK120000149 moeA b0827 865129 866364 reverse molybdopterin molybdotransferase b0827 ECK120002269 iaaA b0828 866568 867533 forward isoaspartyl dipeptidase proenzyme b0828 ECK120003029 gsiA b0829 867520 869391 forward glutathione ABC transporter ATP binding subunit GsiA 22215971,31438868, b0829 ECK120003030 gsiB b0830 869411 870949 forward glutathione ABC transporter periplasmic binding protein b0830 ECK120003031 gsiC b0831 870967 871887 forward glutathione ABC transporter membrane subunit GsiC b0831 ECK120003032 gsiD b0832 871890 872801 forward glutathione ABC transporter membrane subunit GsiD b0832 ECK120003033 pdeI b0833 872979 875327 forward putative c-di-GMP phosphodiesterase PdeI 18239914, b0833 ECK120003034 dgcI b0834 875335 876663 forward putative diguanylate cyclase DgcI 26303830,32053772, b0834 ECK120003035 rimO b0835 876710 878035 reverse ribosomal protein S12 methylthiotransferase RimO b0835 ECK120003036 bssR b0836 878248 878631 forward regulator of biofilm formation [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 11101804,16597943, Weak b0836 ECK120003037 yliI b0837 878742 879857 forward aldose sugar dehydrogenase YliI b0837 ECK120003038 gstB b0838 879854 880480 reverse glutathione -transferase GstB 14635120, b0838 ECK120000197 dacC b0839 880727 881929 forward D-alanyl-D-alanine carboxypeptidase DacC b0839 ECK120000217 deoR b0840 881976 882734 reverse DNA-binding transcriptional repressor DeoR [EXP|W|Inferred from experiment] 2653814,2994018, Weak b0840 ECK120003039 ybjG b0841 882792 883388 reverse undecaprenyl pyrophosphate phosphatase [EXP-IMP|W|Inferred from mutant phenotype] 15778224,23912810,26045332, Weak b0841 ECK120003040 mdfA b0842 883673 884905 forward multidrug efflux pump MdfA / Na antiporter 10022825,10809693,17407265,26238402,27050393,28695852,29177828,29530612,29574104,31240248,31251753, b0842 ECK120003041 ybjH b0843 884946 885230 reverse uncharacterized protein YbjH b0843 ECK120003042 ybjI b0844 885316 886131 reverse 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 15808744, Weak b0844 ECK120003043 ybjJ b0845 886131 887339 reverse inner membrane protein YbjJ 31438868, b0845 ECK120003044 rcdA b0846 887423 887959 forward RcdA b0846 ECK120002591 rybB b4417 887979 888057 reverse small regulatory RNA RybB [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 11445539,17007876,17416652,21768388,22439016,25001303,25030700,25582129,26484242,26992034,30287822, Weak b4417 ECK120003045 ybjL b0847 888134 889819 reverse putative transport protein YbjL b0847 ECK120003046 ybjM b0848 890089 890466 forward putative inner membrane protein b0848 ECK120000410 grxA b0849 890496 890753 reverse reduced glutaredoxin 1 [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10593884,11898418,11898436,12135599,12682041,12766418,14675753,15833738,18548475,19164554,19555372,20458372,20609901,25350574,26634969,2663852,26732755,27277520,28963348,32481517,3286320,33166917,34620,3530878,372193,3911009,6378624,6753845,7030783,7040106,7476363,7476364,7476377,7713872,8206982,8436120,8436944,8914272,9261111,9743619,9989580, Strong b0849 ECK120002395 ybjC b0850 890913 891200 forward DUF1418 domain-containing protein YbjC b0850 ECK120001236 nfsA b0851 891184 891906 forward NADPH-dependent nitro/quinone reductase NfsA 20083491,22173483,23698620,24996412,27166377,27453434,28262557,29740005,30134191,30352235,31131470,32021829,32798330,32929365, b0851 ECK120000843 rimK b0852 891967 892869 forward ribosomal protein S6 modification protein b0852 ECK120003047 ybjN b0853 892957 893433 forward protein YbjN b0853 ECK120001577 potF b0854 893784 894896 forward putrescine ABC transporter periplasmic binding protein 33406388, b0854 ECK120001578 potG b0855 894991 896124 forward putrescine ABC transporter ATP binding subunit b0855 ECK120001579 potH b0856 896134 897087 forward putrescine ABC transporter membrane subunit PotH b0856 ECK120001580 potI b0857 897084 897929 forward putrescine ABC transporter membrane subunit PotI b0857 ECK120003048 ybjO b0858 897989 898477 forward putative inner membrane protein b0858 ECK120003049 rlmC b0859 898518 899645 forward 23S rRNA mU747 methyltransferase b0859 ECK120001576 artJ b0860 899844 900575 reverse L-arginine ABC transporter periplasmic binding protein b0860 ECK120001575 artM b0861 900866 901534 reverse L-arginine ABC transporter membrane subunit ArtM b0861 ECK120001574 artQ b0862 901534 902250 reverse L-arginine ABC transporter membrane subunit ArtQ 28911185, b0862 ECK120001573 artI b0863 902257 902988 reverse putative ABC transporter periplasmic binding protein ArtI 11528004, b0863 ECK120001572 artP b0864 903006 903734 reverse L-arginine ABC transporter ATP binding subunit b0864 ECK120003050 ybjP b0865 903952 904467 reverse DUF3828 domain-containing lipoprotein YbjP 32053772, b0865 ECK120003051 ybjQ b0866 904593 904916 forward putative heavy metal binding protein YbjQ b0866 ECK120003052 amiD b0867 904913 905743 forward -acetylmuramoyl-L-alanine amidase D 19237650,20036252,32053772, b0867 ECK120003053 ybjS b0868 905740 906753 reverse putative epimerase YbjS b0868 ECK120003054 ybjT b0869 906852 908282 reverse putative NAD(P)-binding protein YbjT b0869 ECK120003055 ltaE b0870 908293 909294 reverse low-specificity L-threonine aldolase 24165453,25560296, b0870 ECK120000745 poxB b0871 909331 911049 reverse pyruvate oxidase 12835924,14982993,15529741,16179798,16187334,16310273,17224607,17689798,17979199,1832150,18679018,19125225,19452501,19563847,20012884,20440535,20707865,21718532,22843529,24212579,24375081,3524564,3928620,5336022,6209262,7695848,7785840,8596457,9655909, b0871 ECK120003056 hcr b0872 911182 912150 reverse NADH oxidoreductase b0872 ECK120003057 hcp b0873 912162 913814 reverse protein -nitrosylase [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 10651802,16261196,20533909,29358078, Weak b0873 ECK120003058 lysO b0874 913958 914857 reverse L-lysine/thialysine exporter b0874 ECK120002435 aqpZ b0875 915352 916047 reverse water channel AqpZ 10873451,11226336,11493683,12029329,14630323,14711520,16084383,16225876,16385074,16399837,20855585,22392432,29943128,31717877,31765130,34624277,9137831,9468603, b0875 ECK120003059 ybjD b0876 916473 918131 forward DUF2813 domain-containing protein YbjD b0876 ECK120003060 ybjX b0877 918128 919120 reverse DUF535 domain-containing protein YbjX b0877 ECK120003061 macA b0878 919235 920350 forward ABC-type tripartite efflux pump membrane fusion protein 19805313,27105118, b0878 ECK120003062 macB b0879 920347 922293 forward ABC-type tripartite efflux pump ATP binding/membrane subunit 11566977,27050393,27105118,29061301,31251753, b0879 ECK120001097 cspD b0880 922366 922590 reverse DNA replication inhibitor CspD 11298285,30678142,32162674, b0880 ECK125286421 yljB b4770 922740 922814 forward protein YljB b4770 ECK120003063 clpS b0881 922913 923233 forward specificity factor for ClpA-ClpP chaperone-protease complex [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 11931773, Weak b0881 ECK120000152 clpA b0882 923264 925540 forward ATP-dependent Clp protease ATP-binding subunit ClpA b0882 ECK120002538 serW b0883 925884 925971 reverse tRNA-Ser(GGA) [AS-TAS|W|Traceable author statement] 7033244, Weak b0883 ECK120000497 infA b0884 926225 926443 reverse translation initiation factor IF-1 [EXP|W|Inferred from experiment] 28968100,31108498, Weak b0884 ECK120001098 aat b0885 926728 927432 reverse leucyl/phenylalanyl-tRNA—protein transferase b0885 ECK120000010 cydC b0886 927474 929195 reverse glutathione/L-cysteine ABC exporter subunit CydC 28911185,32900959, b0886 ECK120001371 cydD b0887 929196 930962 reverse glutathione/L-cysteine ABC exporter subunit CydD 31438868,32900959, b0887 ECK120001021 trxB b0888 931085 932050 reverse thioredoxin reductase 2989245, b0888 ECK120000540 lrp b0889 932595 933089 forward DNA-binding transcriptional dual regulator Lrp 1346534,1729203,2040596,7665463, b0889 ECK120003064 ftsK b0890 933224 937213 forward cell division DNA translocase FtsK [EXP-IMP|W|Inferred from mutant phenotype] 19057667,25002583,7592387, Weak b0890 ECK120003065 lolA b0891 937372 937983 forward outer membrane lipoprotein carrier protein [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 16091355,18029423,18218629,18503771,18621730,20802033,33577754,34070637,7628437, Strong b0891 ECK120002355 rarA b0892 937994 939337 forward replication-associated recombination protein A b0892 ECK120000936 serS b0893 939428 940720 forward serine—tRNA ligase b0893 ECK120000226 dmsA b0894 940959 943403 forward dimethyl sulfoxide reductase subunit A 10801884, b0894 ECK120000227 dmsB b0895 943414 944031 forward dimethyl sulfoxide reductase subunit B b0895 ECK120000228 dmsC b0896 944033 944896 forward dimethyl sulfoxide reductase subunit C b0896 ECK120001218 ycaC b0897 944931 945557 reverse putative hydrolase YcaC 9782055, b0897 ECK120001219 ycaD b0898 945871 947019 forward putative transporter YcaD 24391520,31438868, b0898 ECK120003066 ycaM b0899 947229 948659 forward putative transporter YcaM [EXP-IMP|W|Inferred from mutant phenotype] 15380559,31438868, Weak b0899 ECK120003067 ycaN b0900 948660 949568 reverse putative DNA-binding transcriptional regulator YcaN [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b0900 ECK120002361 ycaK b0901 949668 950258 forward putative oxidoreductase YcaK 24391520, b0901 ECK120000025 pflA b0902 950340 951080 reverse pyruvate formate-lyase activating enzyme 15781419,19055729,23274360,24324879,25178795,25482228,27067372,28237496,28768413,30097096,30316699,30647652,6369325,971302, b0902 ECK120000693 pflB b0903 951272 953554 reverse pyruvate formate-lyase 1917868,3053170,3053657,6758723, b0903 ECK120001233 focA b0904 953609 954466 reverse formate channel FocA 2651404, b0904 ECK120003068 ycaO b0905 954872 956632 reverse ribosomal protein S12 methylthiotransferase accessory factor YcaO [EXP-IMP|W|Inferred from mutant phenotype] 12900028,21169565, Weak b0905 ECK120003069 ycaP b0906 956762 957454 forward DUF421 domain-containing protein YcaP b0906 ECK120000935 serC b0907 957653 958741 forward phosphoserine/phosphohydroxythreonine aminotransferase 20823845,23417802,23815967,24997624,26416585,29494135,30925016,31557000, b0907 ECK120000069 aroA b0908 958812 960095 forward 3-phosphoshikimate 1-carboxyvinyltransferase b0908 ECK120003070 ycaL b0909 960264 961028 forward periplasmic protease YcaL 7836281, b0909 ECK120001239 cmk b0910 961201 961884 forward cytidylate kinase 24658737,25735767,27718375,32781536,32808670, b0910 ECK120000891 rpsA b0911 961995 963668 forward 30S ribosomal subunit protein S1 21717022,21972224,22389479,23033476,24169950,24682851,25586496,25845584,25976788,26232079,27992588,28027957,29679401,30566952,30668774,359353, b0911 ECK120000434 ihfB b0912 963828 964112 forward integration host factor subunit β 28968100,7651128,7715442, b0912 ECK120002243 ycaI b0913 964320 966584 forward metallo-β-lactamase superfamily inner membrane protein YcaI b0913 ECK120000606 msbA b0914 966621 968369 forward ATP-binding lipopolysaccharide transport protein 11546861,11685233,11782503,11921393,12195740,12667056,13678821,15339914,15890866,15890884,16511120,16782794,17185570,17185584,17965211,18024585,18803398,19132955,20412049,21462989,22523072,29937358, b0914 ECK120001375 lpxK b0915 968366 969352 forward tetraacyldisaccharide 4'-kinase 1323052, b0915 ECK120003071 ycaQ b0916 969389 970621 forward interstrand DNA crosslink repair glycosylase b0916 ECK120003072 ycaR b0917 970673 970855 forward PF03966 family protein YcaR 34070637, b0917 ECK120000512 kdsB b0918 970852 971598 forward 3-deoxy--octulosonate cytidylyltransferase 21669179, b0918 ECK120003073 ycbJ b0919 971752 972645 forward putative phosphotransferase YcbJ b0919 ECK120002062 elyC b0920 972622 973401 reverse envelope biogenesis factor [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 24391520, Strong b0920 ECK120002063 cmoM b0921 973537 974322 forward tRNA U34 methyltransferase b0921 ECK120002061 mukF b0922 974319 975641 forward chromosome partitioning protein MukF 34070637, b0922 ECK120001227 mukE b0923 975622 976326 forward chromosome partitioning protein MukE 21855551,34070637, b0923 ECK120000611 mukB b0924 976326 980786 forward chromosome partitioning protein MukB 24097060,34070637, b0924 ECK120001228 ldtD b0925 981047 982894 forward L,D-transpeptidase LdtD 27767957,31743648, b0925 ECK120003074 mepK b0926 983075 983623 forward peptidoglycan L,D-endopeptidase b0926 ECK120003075 gloC b0927 983650 984297 forward hydroxyacylglutathione hydrolase GloC 24391520, b0927 ECK120000092 aspC b0928 984519 985709 reverse aspartate aminotransferase b0928 ECK120000664 ompF b0929 985894 986982 reverse outer membrane porin F 10427722,10920012,11371193,11444879,12079356,12270719,12804762,12882645,12914905,1331031,1375155,14633108,14747308,16153185,16183883,16352602,16385048,1662760,16769257,16782785,16858566,1696133,16997866,17292122,18369514,18641391,18986168,19134471,19473960,19721064,2040634,20441746,20521145,20590090,20923644,21046046,21134352,21156129,2168378,2170338,23008773,2459611,2464593,2481821,2580220,26209678,26314242,26895142,27105118,28072422,28094462,2820945,28341438,28485920,28553265,29166022,29518576,2981807,29949342,30125859,3023382,31593635,3275653,33004891,34060805,34515361,3533941,3540530,357416,4609976,6254441,6294623,6302079,6350261,6378888,6450750,7044306,7678960,7701347,8020499,806476,9466900,9635733, b0929 ECK120000090 asnS b0930 987585 988985 reverse asparagine—tRNA ligase 6450750,8223640,8479423, b0930 ECK120000733 pncB b0931 989154 990356 reverse nicotinate phosphoribosyltransferase 4312778, b0931 ECK120000688 pepN b0932 990622 993234 forward aminopeptidase N 2436977,2869947,3018440,3549459,355237,6140621,6147745,792681, b0932 ECK120002226 ssuB b0933 993277 994044 reverse aliphatic sulfonate ABC transporter ATP binding subunit b0933 ECK120003076 ssuC b0934 994041 994832 reverse aliphatic sulfonate ABC transporter membrane subunit 31438868, b0934 ECK120003077 ssuD b0935 994843 995988 reverse FMNH-dependent alkanesulfonate monooxygenase b0935 ECK120003078 ssuA b0936 995985 996944 reverse aliphatic sulfonate ABC transporter periplasmic binding protein 34787438, b0936 ECK120003079 ssuE b0937 996937 997512 reverse NADPH-dependent FMN reductase b0937 ECK120003080 elfA b0938 997868 998407 forward putative laminin-binding fimbrial subunit [EXP-IDA-PART-PURIFIED-PROTEIN-NH|W|Assay of protein partially-purified from its native host],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825, Weak b0938 ECK120003081 elfD b0939 998490 999191 forward putative fimbrial chaperone ElfD [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 11514505,12192075,20345943,21344461,23382825, Weak b0939 ECK120003082 elfC b0940 999216 1001816 forward putative fimbrial usher protein ElfC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 12192075,20345943,21344461,23382825, Weak b0940 ECK120003083 elfG b0941 1001807 1002877 forward putative fimbrial-like adhesin protein [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,27718375, Weak b0941 ECK120003084 ycbU b0942 1002889 1003431 forward putative fimbrial protein YcbU [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825, Weak b0942 ECK120003085 ycbV b0943 1003439 1003954 forward putative fimbrial protein YcbV [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825, Weak b0943 ECK120002260 ycbF b0944 1003947 1004657 forward putative fimbrial chaperone YcbF [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 12192075,21344461,23382825, Weak b0944 ECK120000798 pyrD b0945 1004768 1005778 forward dihydroorotate dehydrogenase, type 2 338583, b0945 ECK120003086 zapC b0946 1005952 1006494 forward cell division protein ZapC [EXP-IPI|W|Inferred from physical interaction],[EXP-IGI|W|Inferred from genetic interaction] 21216995,21216997,28695917, Weak b0946 ECK120003087 ycbX b0947 1006491 1007600 reverse 6--hydroxylaminopurine resistance protein [EXP-IMP|W|Inferred from mutant phenotype] 18312271, Weak b0947 ECK120003088 rlmL b0948 1007844 1009952 forward fused 23S rRNA mG2069 methyltransferase b0948 ECK120003089 uup b0949 1009964 1011871 forward ATP-binding protein Uup [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 16407313,28641943,9383047, Weak b0949 ECK120003090 pqiA b0950 1012001 1013254 forward intermembrane transport protein PqiA [EXP-IEP|W|Inferred from expression pattern],[EXP-IGI|W|Inferred from genetic interaction] 27795327,28388411,32359438,7751275, Weak b0950 ECK120003091 pqiB b0951 1013259 1014899 forward intermembrane transport protein PqiB b0951 ECK120003092 pqiC b0952 1014896 1015459 forward intermembrane transport lipoprotein PqiC [EXP-IGI|W|Inferred from genetic interaction] 27795327,28388411,32053772, Weak b0952 ECK120002563 rmf b0953 1015715 1015882 forward ribosome modulation factor [EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 10543985,11443083,15743942,15831252,17277072,18627072,20628056,28431088,34486756,7677746,8440252,9639823,9863196, Weak b0953 ECK120000267 fabA b0954 1015952 1016470 reverse β-hydroxyacyl-acyl carrier protein dehydratase/isomerase 1505031,19679654,21276098,2832401,4562395,6341354, b0954 ECK120003093 ycbZ b0955 1016539 1018299 reverse putative ATP-dependent protease YcbZ b0955 ECK120002403 matP b0956 1018485 1018937 forward macrodomain Ter protein 19951655,22532809,22820946,23632166,23859153,26762981,28358835,31266871, b0956 ECK120000662 ompA b0957 1019013 1020053 reverse outer membrane protein A 12124263,16352602,16719475,17260943,17564441,17601489,18318713,18641391,18991402,1934062,20170640,20491126,20945359,21539779,2170338,2172552,21782315,2211627,23056562,23522061,23641708,23763479,2498289,2553715,26196893,29094406,3025450,30442809,3049077,3058693,3275642,3298231,33577754,33947759,34716276,6298577,6366795,7001461,7037401,7796962,8177210,8245002,8771211,8830709, b0957 ECK120000973 sulA b0958 1020410 1020919 reverse cell division inhibitor SulA [EXP-IDA|W|Inferred from direct assay] 10339542,12670962,14515458,15037245,2211499,2254289,23345702,2656652,26644431,2830228,2988407,3297925,342340,3514208,3528842,3890692,3911030,6296040,6327610,6336731,6343799,6348474,6361003,6780758,6814510,6814518,6821127,7026534,7504191,7997162,9501185, Weak b0958 ECK120003094 sxy b0959 1021138 1021767 forward transcriptional coactivator for CRP [EXP-IMP|W|Inferred from mutant phenotype] 17068078,25491382, Weak b0959 ECK120003095 yccS b0960 1021730 1023883 reverse putative transporter YccS 31438868, b0960 ECK120003096 yccF b0961 1023902 1024348 reverse PF03733 family inner membrane protein YccF b0961 ECK120000419 helD b0962 1024471 1026525 forward DNA helicase IV [EXP-IMP|W|Inferred from mutant phenotype] 16164551,21938951,7868608,8202362,8647383, Weak b0962 ECK120003097 mgsA b0963 1026557 1027015 reverse methylglyoxal synthase b0963 ECK120003098 yccT b0964 1027111 1027773 reverse DUF2057 domain-containing protein YccT b0964 ECK120003099 yccU b0965 1027946 1028359 forward putative HspQ acetyl donor [COMP-HINF-SEQ-ORTHOLOGY|W|Human inference of function by sequence orthology] 31371438,9868784, Weak b0965 ECK120003100 hspQ b0966 1028404 1028721 reverse heat shock protein HspQ b0966 ECK120003101 rlmI b0967 1028779 1029969 reverse 23S rRNA mC1962 methyltransferase b0967 ECK120003102 yccX b0968 1030064 1030342 forward acylphosphatase b0968 ECK120002415 tusE b0969 1030339 1030668 reverse sulfur transfer protein TusE [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 16387657,34070637, Weak b0969 ECK120001099 yccA b0970 1030759 1031418 reverse modulator of FtsH protease [EXP-IMP|W|Inferred from mutant phenotype] 10077851,12081643,14659883,9636708, Weak b0970 ECK120002535 serT b0971 1031625 1031712 reverse tRNA-Ser(UGA) [AS-TAS|W|Traceable author statement] 7033244, Weak b0971 ECK120000461 hyaA b0972 1032139 1033257 forward hydrogenase 1 small subunit b0972 ECK120000462 hyaB b0973 1033254 1035047 forward hydrogenase 1 large subunit 1558764,30070475,33753519, b0973 ECK120000463 hyaC b0974 1035066 1035773 forward hydrogenase 1 cytochrome subunit b0974 ECK120000464 hyaD b0975 1035770 1036357 forward putative hydrogenase 1 maturation protease HyaD [EXP-IMP|W|Inferred from mutant phenotype] 1856178, Weak b0975 ECK120000465 hyaE b0976 1036354 1036752 forward putative HyaA chaperone [EXP-IPI|W|Inferred from physical interaction] 12914940, Weak b0976 ECK120000466 hyaF b0977 1036749 1037606 forward protein HyaF b0977 ECK120001348 appC b0978 1037740 1039284 forward cytochrome -II subunit 1 b0978 ECK120001347 appB b0979 1039296 1040432 forward cytochrome -II subunit 2 26100898, b0979 ECK120030072 appX b4592 1040445 1040537 forward cytochrome -II accessory subunit AppX b4592 ECK120000045 appA b0980 1040617 1041915 forward periplasmic phosphoanhydride phosphatase/multiple inositol-polyphosphate phosphatase 2168385,2993816, b0980 ECK120001758 etk b0981 1042030 1044210 reverse protein-tyrosine kinase Etk [EXP|W|Inferred from experiment] 10369665,19258536, Weak b0981 ECK120003103 etp b0982 1044230 1044676 reverse phosphotyrosine-protein phosphatase Etp [EXP|W|Inferred from experiment] 11090276, Weak b0982 ECK120003104 gfcE b0983 1044664 1045803 reverse putative exopolysaccharide export lipoprotein GfcE 19258536,32053772, b0983 ECK120003105 gfcD b0984 1045849 1047945 reverse putative lipoprotein GfcD 32053772, b0984 ECK120003106 gfcC b0985 1047945 1048691 reverse capsule biosynthesis GfcC family protein 21449614, b0985 ECK120003107 gfcB b0986 1048688 1049332 reverse lipoprotein GfcB 32053772, b0986 ECK120003108 gfcA b0987 1049439 1049744 reverse threonine-rich inner membrane protein GfcA b0987 ECK120016282 insA4 b4516 1049833 1050108 forward IS1 protein InsA b4516 ECK120023912 insAB4 1049833 1050530 forward InsAB' transposase [EXP-IMP|W|Inferred from mutant phenotype] 8083181, Weak ECK120003109 insB4 b0988 1050027 1050530 forward IS1 protein InsB [EXP-IMP|W|Inferred from mutant phenotype] 8083181, Weak b0988 ECK120003110 cspH b0989 1050963 1051175 reverse CspA family protein CspH 21700661,32162674,32753505, b0989 ECK120003111 cspG b0990 1051461 1051673 forward cold shock protein CspG [EXP-IEP|W|Inferred from expression pattern],[EXP-IGI|W|Inferred from genetic interaction] 11298285,19824539,21700661,25637299,32162674,32753505,8631696, Weak b0990 ECK125256966 ymcF b4723 1051684 1051872 forward protein YmcF b4723 ECK120003112 ymcE b0991 1051847 1052077 forward protein YmcE b0991 ECK120002666 gnsA b4517 1052067 1052240 forward putative phosphatidylethanolamine synthesis regulator GnsA b4517 ECK120003113 yccM b0992 1052289 1053362 reverse putative electron transport protein YccM b0992 ECK120003114 torS b0993 1053434 1056178 reverse sensor histidine kinase TorS [EXP-IMP|W|Inferred from mutant phenotype] 19748340,8809780, Weak b0993 ECK120003115 torT b0994 1056261 1057289 forward periplasmic trimethylamine-N-oxide binding protein [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 17040909,8576063, Weak b0994 ECK120002334 torR b0995 1057262 1057954 reverse DNA-binding transcriptional dual regulator TorR b0995 ECK120001748 torC b0996 1058084 1059256 forward cytochrome menaquinol dehydrogenase TorC b0996 ECK120001747 torA b0997 1059256 1061802 forward trimethylamine -oxide reductase 1 29334455,29593092,29947971, b0997 ECK120002084 torD b0998 1061799 1062398 forward trimethylamine-N-oxide reductase-specific chaperone [EXP|W|Inferred from experiment] 12766163,15213747,15385959,15941830,16253369,16337610,17107419,18522945,19519768,20064164,20974141,23452237,24211448,25157671,34499687, Weak b0998 ECK120002083 cbpM b0999 1062550 1062855 reverse chaperone modulator CbpM [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 15184371, Weak b0999 ECK120002082 cbpA b1000 1062855 1063775 reverse curved DNA-binding protein [EXP-IDA|W|Inferred from direct assay],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IGI|W|Inferred from genetic interaction] 10947847,15184371,15489435,15792799,16973605,17337578,18502857,20226195,20633229,2126011,21683710,23341772,23651594,24945826,25670677,33310019,8302830, Weak b1000 ECK120002085 yccE b1001 1064036 1065292 forward uncharacterized protein YccE 24391520, b1001 ECK120000030 agp b1002 1065585 1066826 forward glucose-1-phosphatase 2153660,2542226,2844729, b1002 ECK120002362 yccJ b1003 1066864 1067091 reverse PF13993 family protein YccJ b1003 ECK120001494 wrbA b1004 1067112 1067708 reverse NAD(P)H:quinone oxidoreductase 20409720,25403562, b1004 ECK120003116 ycdF b1005 1067918 1068148 forward b1005 ECK120016295 ymdF b4518 1068081 1068254 forward stress-induced bacterial acidophilic repeat motifs-containing protein YmdF 30373755, b4518 ECK120003117 rutG b1006 1068511 1069839 reverse pyrimidine:H symporter 31438868, b1006 ECK120003118 rutF b1007 1069860 1070354 reverse FMN reductase RutF [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 11121068,16540542, Weak b1007 ECK120003119 rutE b1008 1070365 1070955 reverse putative malonic semialdehyde reductase [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 11121068,16540542, Weak b1008 ECK120003120 rutD b1009 1070965 1071765 reverse putative aminoacrylate hydrolase RutD b1009 ECK120003121 rutC b1010 1071773 1072159 reverse 3-aminoacrylate deaminase b1010 ECK120003122 rutB b1011 1072171 1072863 reverse ureidoacrylate amidohydrolase b1011 ECK120003123 rutA b1012 1072863 1074011 reverse pyrimidine monooxygenase RutA 31072497, b1012 ECK120002180 rutR b1013 1074242 1074880 forward DNA-binding transcriptional dual regulator RutR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 15556475,16540542,17919280, Weak b1013 ECK120000792 putA b1014 1074920 1078882 reverse fused DNA-binding transcriptional repressor / proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase PutA 11294639, b1014 ECK125276511 ymdG b4737 1079120 1079146 forward protein YmdG b4737 ECK120000793 putP b1015 1079305 1080813 forward proline:Na symporter 10521259,12923181,9109673,9753469, b1015 ECK120003124 efeU b4490 1081356 1082185 forward inactive ferrous iron permease EfeU 15066794,16199566, b1016,b1017,b4490 ECK120003125 efeO b1018 1082243 1083370 forward ferrous iron transport system protein EfeO 12746439,15601715, b1018 ECK120001674 efeB b1019 1083376 1084647 forward heme-containing peroxidase/deferrochelatase 16321939, b1019 ECK120001673 phoH b1020 1084992 1086056 forward ATP-binding protein PhoH 12762842,30904393, b1020 ECK120003126 pgaD b1021 1086106 1086519 reverse poly--acetyl-D-glucosamine synthase subunit PgaD b1021 ECK120003127 pgaC b1022 1086521 1087846 reverse poly--acetyl-D-glucosamine synthase subunit PgaC b1022 ECK120003128 pgaB b1023 1087839 1089857 reverse poly-β-1,6--deacetylase and β-1,6 glycoside hydrolase 16321928,31642455,32053772, b1023 ECK120003129 pgaA b1024 1089866 1092289 reverse partially deacetylated poly-β-1,6--acetyl-D-glucosamine export outer membrane porin 16321928,26957546,31915750, b1024 ECK120003130 dgcT b1025 1092876 1094234 forward probable diguanylate cyclase DgcT 23202856,23666921, b1025 ECK120023910 insEF4 1094275 1095437 reverse IS3 element transposase ECK120003131 insF4 b1026 1094275 1095141 reverse IS3 element protein InsF b1026 ECK120003132 insE4 b1027 1095138 1095437 reverse IS3 element protein InsE b1027 ECK120003133 ymdE b1028 1095544 1095846 forward putative uncharacterized protein YmdE b1028 ECK120003134 ycdU b1029 1095843 1096829 forward uncharacterized protein YcdU b1029 ECK120002539 serX b1032 1097565 1097652 reverse tRNA-Ser(GGA) [AS-TAS|W|Traceable author statement] 7033244, Weak b1032 ECK120003135 ghrA b1033 1097886 1098824 forward glyoxylate/hydroxypyruvate reductase A 27702485,29494135, b1033 ECK120003136 ycdX b1034 1098879 1099616 forward zinc-binding phosphatase YcdX b1034 ECK120003137 ycdY b1035 1099640 1100194 forward chaperone protein YcdY b1035 ECK120003138 ycdZ b1036 1100296 1100787 forward inner membrane protein YcdZ 23028500, b1036 ECK120003139 csgG b1037 1100851 1101684 reverse curli secretion channel [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 12876315,15174130,16420357,30444973,32053772,8817489, Weak b1037 ECK120003140 csgF b1038 1101711 1102127 reverse curli assembly component CsgF [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 29427517,8817489, Weak b1038 ECK120003141 csgE b1039 1102152 1102541 reverse curli assembly component CsgE [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 25219853,26418947,8817489, Weak b1039 ECK120003142 csgD b1040 1102546 1103196 reverse DNA-binding transcriptional dual regulator CsgD [EXP|W|Inferred from experiment] Weak b1040 ECK120003143 csgB b1041 1103951 1104406 forward curlin, minor subunit [EXP-IMP|W|Inferred from mutant phenotype],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 17636121,19574225,22493266,24097954,29533854,30271935,30918257,33385820,8817489, Strong b1041 ECK120001445 csgA b1042 1104447 1104902 forward curlin, major subunit [EXP-IDA|W|Inferred from direct assay] 11823641,1357528,17636121,28138525,29533854,30018113,30271935,30338995,31003987,31469892,31915750,31932609,32490204,32528432,33385820,8459772,9383186, Weak b1042 ECK120003144 csgC b1043 1104961 1105293 forward curlin chaperone 21206057, b1043 ECK120003145 ymdA b1044 1105414 1105725 forward uncharacterized protein YmdA [EXP-IMP|W|Inferred from mutant phenotype] 29150605,32934077, Weak b1044 ECK120003146 ymdB b1045 1105820 1106353 forward 2'--acetyl-ADP-ribose deacetylase, regulator of RNase III activity b1045 ECK120003147 clsC b1046 1106355 1107776 forward cardiolipin synthase C 28815570,31235517,33833055, b1046 ECK120003148 opgC b1047 1107784 1108941 reverse osmoregulated periplasmic glucans (OPG) biosynthesis protein C [EXP-IMP|W|Inferred from mutant phenotype] 10368134,12027885, Weak b1047 ECK120001815 opgG b1048 1109335 1110870 forward osmoregulated periplasmic glucans biosynthesis protein G [EXP-IMP|W|Inferred from mutant phenotype] 1370954,15313617,1834913,2552262,325003,330527,33846116,385596,6238027, Weak b1048 ECK120001816 opgH b1049 1110863 1113406 forward osmoregulated periplasmic glucans biosynthesis protein H [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ] 1827116,1834913,20358372,23935518,24228245,2552262,28593831,325003,330527,33846116,385596,3941890,6238027,6330111,7814331,7934824,9171419,9352941, Weak b1049 ECK120002354 yceK b1050 1113579 1113806 forward DUF1375 domain-containing lipoprotein YceK b1050 ECK120001309 msyB b1051 1113807 1114181 reverse acidic protein MsyB b1051 ECK120003149 b1052 b1052 1114211 1114309 reverse ECK120001314 mdtG b1053 1114264 1115490 reverse efflux pump MdtG 31438868, b1053 ECK120000457 lpxL b1054 1115662 1116582 reverse lauroyl acyltransferase b1054 ECK120001100 trhO b1055 1116807 1117859 forward tRNA U34 hydroxylase TrhO [EXP-IMP|W|Inferred from mutant phenotype] 31253794, Weak b1055 ECK120001752 yceI b1056 1117901 1118476 reverse protein YceI b1056 ECK120003150 yceJ b1057 1118480 1119046 reverse putative cytochrome b561 YceJ b1057 ECK120003151 yceO b1058 1119307 1119447 reverse DUF2770 domain-containing protein YceO [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 16385049,19734312, Weak b1058 ECK120003152 solA b1059 1119468 1120586 reverse -methyl-L-tryptophan oxidase b1059 ECK120003153 bssS b1060 1120701 1120955 reverse regulator of biofilm formation [EXP-IMP|W|Inferred from mutant phenotype] 14731270,16597943, Weak b1060 ECK120003154 dinI b1061 1121242 1121487 reverse DNA damage-inducible protein I [EXP|W|Inferred from experiment] Weak b1061 ECK120000797 pyrC b1062 1121561 1122607 reverse dihydroorotase b1062 ECK120001101 yceB b1063 1122713 1123273 reverse putative lipid-binding lipoprotein YceB 21787343,32053772, b1063 ECK120002353 grxB b1064 1123407 1124054 reverse reduced glutaredoxin 2 [EXP-IDA|W|Inferred from direct assay] 10593884,10999632,11035035,11290748,11453697,17401194,9111025,9989580, Weak b1064 ECK120003155 mdtH b1065 1124118 1125326 reverse multidrug efflux pump MdtH b1065 ECK120000842 rimJ b1066 1125562 1126146 forward ribosomal-protein-S5-alanine -acetyltransferase 19352641,22293616,29221124,30211949,3911025, b1066 ECK120001491 yceH b1067 1126157 1126804 forward DUF480 domain-containing protein YceH 24391520, b1067 ECK120003156 yceM b1068 1126806 1127729 forward putative oxidoreductase YceM b1068 ECK120003157 murJ b1069 1127839 1129374 forward lipid II flippase MurJ 12975657,15819979,15930492,16672535,17021100,27537185, b1069 ECK120003158 flgN b1070 1129414 1129830 reverse flagellar biosynthesis protein FlgN b1070 ECK120002689 flgM b1071 1129835 1130128 reverse anti-sigma factor for FliA (σ) [EXP|W|Inferred from experiment] 17537210,23554966,23867204, Weak b1071 ECK120002678 flgA b1072 1130204 1130863 reverse flagellar basal body P-ring formation protein FlgA [EXP-IMP|W|Inferred from mutant phenotype] 25816013,3549689, Weak b1072 ECK120002679 flgB b1073 1131018 1131434 forward flagellar basal-body rod protein FlgB [EXP-IMP|W|Inferred from mutant phenotype] 7007337, Weak b1073 ECK120002680 flgC b1074 1131438 1131842 forward flagellar basal-body rod protein FlgC [EXP-IMP|W|Inferred from mutant phenotype] 7007337, Weak b1074 ECK120002682 flgD b1075 1131854 1132549 forward flagellar biosynthesis, initiation of hook assembly b1075 ECK120002683 flgE b1076 1132574 1133782 forward flagellar hook protein FlgE b1076 ECK120002684 flgF b1077 1133802 1134557 forward flagellar basal-body rod protein FlgF [EXP-IMP|W|Inferred from mutant phenotype] 7007337, Weak b1077 ECK120002685 flgG b1078 1134729 1135511 forward flagellar basal-body rod protein FlgG [EXP-IMP|W|Inferred from mutant phenotype] 1640458,2129540,25816013,28120828,28429800,7007337, Weak b1078 ECK120002686 flgH b1079 1135564 1136262 forward flagellar L-ring protein 32053772, b1079 ECK120002687 flgI b1080 1136274 1137371 forward flagellar P-ring protein [EXP-IMP|W|Inferred from mutant phenotype] 18310027,20576620,3549690, Weak b1080 ECK120002688 flgJ b1081 1137371 1138312 forward putative peptidoglycan hydrolase FlgJ [EXP-IMP|W|Inferred from mutant phenotype] 25816013, Weak b1081 ECK120001893 flgK b1082 1138378 1140021 forward flagellar hook-filament junction protein 1 b1082 ECK120001499 flgL b1083 1140033 1140986 forward flagellar hook-filament junction protein 2 8158647, b1083 ECK125303710 flgO b4826 1140986 1141063 forward small RNA FlgO b4826 ECK120000850 rne b1084 1141182 1144367 reverse ribonuclease E b1084 ECK120003159 yceQ b1085 1144502 1144822 forward DUF2655 domain-containing protein YceQ b1085 ECK120001102 rluC b1086 1144940 1145899 forward 23S rRNA pseudouridine synthase 8871555, b1086 ECK120001402 yceF b1087 1146011 1146595 reverse mGTP pyrophosphatase b1087 ECK120002575 sraB b4418 1146589 1146757 forward small RNA SraB 11448770,12202758, b4418 ECK120001103 yceD b1088 1146794 1147315 forward DUF177 domain-containing protein YceD b1088 ECK120000881 rpmF b1089 1147367 1147540 forward 50S ribosomal subunit protein L32 1447160,2477362,2660905,29551268,321934,3315664,340794,362162,3884043,3889589,3911025,6209544,6365649,6750359,7024914,7635191,765258,813873,9642179, b1089 ECK120001401 plsX b1090 1147621 1148691 forward putative phosphate acyltransferase [EXP-IGI|W|Inferred from genetic interaction] 6094487, Weak b1090 ECK120000271 fabH b1091 1148759 1149712 forward 3-oxoacyl-[acyl carrier protein] synthase 3 1551888, b1091 ECK120001288 fabD b1092 1149728 1150657 forward [acyl-carrier-protein] -malonyltransferase 1090584,16978582,22038854,22042840,22112270,22176949,22664193,25863265,26008118,27116968,27642613,6989835,7592873,9721301, b1092 ECK120001289 fabG b1093 1150670 1151404 forward 3-oxoacyl-[acyl-carrier-protein] reductase FabG b1093 ECK120002562 acpP b1094 1151615 1151851 forward acyl carrier protein [EXP|W|Inferred from experiment] Weak b1094 ECK120002329 fabF b1095 1151939 1153180 forward 3-oxoacyl-[acyl carrier protein] synthase 2 7768872,9013860, b1095 ECK120001449 pabC b1096 1153300 1154109 forward aminodeoxychorismate lyase b1096 ECK120001450 mltG b1097 1154112 1155134 forward endolytic murein transglycosylase 34036206, b1097 ECK120002181 tmk b1098 1155124 1155765 forward b1098 ECK120001456 holB b1099 1155762 1156766 forward DNA polymerase III subunit δ' 16083981,8505303,8509334, b1099 ECK120002182 ycfH b1100 1156777 1157574 forward putative metal-dependent hydrolase YcfH b1100 ECK120000778 ptsG b1101 1157869 1159302 forward glucose-specific PTS enzyme IIBC component 10913077,11032802,11032803,11361064,16204242,17158705,20516600,21996078,26285685,3023349,30729074,30800588,8089109,8112346,8784182,9371775,9575173,9748244,9767573,9781886, b1101 ECK120000300 fhuE b1102 1159362 1161551 reverse ferric coprogen/ferric rhodotorulic acid outer membrane transporter b1102 ECK120002067 hinT b1103 1161885 1162244 forward purine nucleoside phosphoramidase 32265328, b1103 ECK120003160 ycfL b1104 1162247 1162624 forward DUF1425 domain-containing protein YcfL b1104 ECK120003161 lpoB b1105 1162638 1163279 forward outer membrane lipoprotein - activator of MrcB activity [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 21183073,21183074,24341982,24821816,30233559,30622193,32053772, Strong b1105 ECK120003162 thiK b1106 1163260 1164084 forward thiamine kinase b1106 ECK120003163 nagZ b1107 1164095 1165120 forward β--acetylglucosaminidase 19617367,34940771,6120994,7925310,87116,9158731, b1107 ECK120003164 ycfP b1108 1165143 1165685 forward PF05728 family protein YcfP b1108 ECK120000642 ndh b1109 1166085 1167389 forward NADH:quinone oxidoreductase II 11807064,15625321,2050655, b1109 ECK120002297 ycfJ b1110 1167599 1168138 forward PF05433 family protein YcfJ [EXP-IMP|W|Inferred from mutant phenotype] 14731270, Weak b1110 ECK120003165 comR b1111 1168200 1168832 reverse DNA-binding transcriptional repressor ComR [EXP-IEP|W|Inferred from expression pattern],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 15556475,22089859, Strong b1111 ECK120003166 bhsA b1112 1169073 1169330 forward DUF1471 domain-containing multiple stress resistance outer membrane protein BhsA [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 14731270,17293424,22089859,33640981, Weak b1112 ECK125303707 bhsB b4832 1169303 1169402 forward small RNA BhsB b4832 ECK120003167 ldtC b1113 1169412 1170374 reverse L,D-transpeptidase LdtC 15774872,31743648,33640981, b1113 ECK120001567 mfd b1114 1170518 1173964 reverse transcription-repair coupling factor [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 12787667,1438310,15687384,16551743,1763073,18707026,1896474,19700770,20638914,21145481,22427630,2250027,22749141,23756341,23828459,28167766,31383358,32198374,32198385,32719356,33480355,8465200, Weak b1114 ECK120003168 ycfT b1115 1174092 1175165 reverse inner membrane protein YcfT [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15044727,24391520, Weak b1115 ECK120003169 lolC b1116 1175427 1176626 forward lipoprotein release complex - inner membrane subunit b1116 ECK120003170 lolD b1117 1176619 1177320 forward lipoprotein release complex - ATP binding subunit b1117 ECK120003171 lolE b1118 1177320 1178564 forward lipoprotein release complex - inner membrane subunit b1118 ECK120003172 nagK b1119 1178593 1179504 forward -acetyl-D-glucosamine kinase 21415116, b1119 ECK120003173 cobB b1120 1179520 1180359 forward CobB-S b1120 ECK120003173 cobB b1120 1179520 1180359 forward protein-lysine deacetylase/desuccinylase/lipoamidase b1120 ECK120003174 ycfZ b1121 1180479 1181267 reverse putative inner membrane protein YcfZ 25774654, b1121 ECK120003175 ymfA b1122 1181264 1181725 reverse putative inner membrane protein YmfA b1122 ECK120000743 potD b1123 1181783 1182829 reverse spermidine preferential ABC transporter periplasmic binding protein 23539287,23792166,8416922,8647815, b1123 ECK120000742 potC b1124 1182826 1183620 reverse spermidine preferential ABC transporter membrane subunit PotC 31438868, b1124 ECK120000741 potB b1125 1183617 1184444 reverse spermidine preferential ABC transporter membrane subunit PotB b1125 ECK120000740 potA b1126 1184458 1185594 reverse spermidine preferential ABC transporter ATP binding subunit b1126 ECK120001503 pepT b1127 1185844 1187070 forward peptidase T b1127 ECK120001394 roxA b1128 1187119 1188240 reverse 50S ribosomal protein L16-arginine 3-hydroxylase b1128 ECK120000723 phoQ b1129 1188316 1189776 reverse sensor histidine kinase PhoQ b1129 ECK120000722 phoP b1130 1189776 1190447 reverse DNA-binding transcriptional dual regulator PhoP [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 1482126,1530848,15703297,2157156,7699720,8098993, Weak b1130 ECK120001285 purB b1131 1190616 1191986 reverse adenylosuccinate lyase 1729205,8969519, b1131 ECK120001316 hflD b1132 1191990 1192631 reverse lysogenization regulator [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IPI|W|Inferred from physical interaction] 11278968, Weak b1132 ECK120001315 mnmA b1133 1192667 1193773 reverse tRNA-specific 2-thiouridylase b1133 ECK120003176 nudJ b1134 1193827 1194288 reverse phosphatase NudJ 19149682,26293337,26774489,29551348, b1134 ECK120003177 rluE b1135 1194298 1194951 reverse 23S rRNA pseudouridine synthase b1135 ECK120000482 icd b1136 1195123 1196373 forward isocitrate dehydrogenase 3112144,4145959,4152156, b1136 ECK120002608 C0293 b4806 1196711 1196782 forward e14 prophage; small regulatory RNA C0293 [EXP-IMP|W|Inferred from mutant phenotype] 32061118, Weak b4806 ECK120003178 ymfD b1137 1196867 1197532 reverse e14 prophage; putative SAM-dependent methyltransferase YmfD b1137 ECK120003179 ymfE b1138 1197533 1198237 reverse e14 prophage; uncharacterized protein YmfE 15919996, b1138 ECK120000528 lit b1139 1198695 1199588 forward e14 prophage; cell death peptidase Lit 9501157, b1139 ECK120002238 intE b1140 1199679 1200806 reverse e14 prophage; putative integrase b1140 ECK120003180 xisE b1141 1200787 1201032 reverse e14 prophage; putative excisionase b1141 ECK120003181 ymfH b1142 1201069 1201380 reverse e14 prophage; putative protein YmfH b1142 ECK120003182 ymfI b1143 1201497 1201838 forward e14 prophage; uncharacterized protein YmfI b1143 ECK120003183 ymfJ b1144 1201776 1202084 reverse e14 prophage; uncharacterized protein YmfJ b1144 ECK120003184 ymfK b1145 1202259 1202933 reverse e14 prophage; putative repressor protein YmfK 3531184, b1145 ECK120003185 ymfT b1146 1203024 1203224 forward e14 prophage; putative DNA-binding transcriptional regulator YmfT b1146 ECK120003186 ymfL b1147 1203268 1203825 forward e14 prophage; uncharacterized protein YmfL b1147 ECK120003187 ymfM b1148 1203822 1204160 forward e14 prophage; cell division inhibitor YmfM [EXP-IMP|W|Inferred from mutant phenotype] 14733619,3011740,33722843,3531184,6352679, Weak b1148 ECK125276500 oweE b4692 1204170 1204403 forward phage replication protein b4692 ECK120003188 ymfN b1149 1204170 1205537 forward e14 prophage; chimeric replication protein/phage terminase YmfN b1149 ECK125276503 aaaE b4693 1204401 1205537 forward phage terminase b4693 ECK120003189 ymfR b1150 1205549 1205731 forward e14 prophage; IPR020297 domain-containing protein YmfR b1150 ECK120003190 beeE b1151 1205731 1206204 forward e14 prophage; protein BeeE b1151 ECK120003191 jayE b1152 1206131 1206922 forward e14 prophage; putative protein JayE b1152 ECK120003192 ymfQ b1153 1206913 1207497 forward e14 prophage; DUF2313 domain-containing protein YmfQ 24391520, b1153 ECK120002416 ycfK b1154 1207501 1208130 forward e14 prophage; protein StfP b1154 ECK120003193 tfaP b1155 1208132 1208545 forward e14 prophage; putative tail fiber assembly protein TfaP b1155 ECK120001104 tfaE b1156 1208517 1209119 reverse e14 prophage; putative tail fiber assembly protein TfaE [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 14733619, Weak b1156 ECK120003194 stfE b1157 1209119 1209655 reverse e14 prophage; putative side tail fiber protein fragment b1157 ECK120000728 pinE b1158 1209685 1210239 forward e14 prophage; site-specific DNA recombinase b1158 ECK120000566 mcrA b1159 1210346 1211179 forward e14 prophage; Type IV methyl-directed restriction enzyme EcoKMcrA 20015968,2548920,30107581,31724709, b1159 ECK120026447 icdC b4519 1211413 1211577 forward protein IcdC b4519 ECK120003195 iraM b1160 1211680 1212003 reverse anti-adaptor protein IraM [EXP-IDA|W|Inferred from direct assay] 18383615,34070637, Weak b1160 ECK125276520 ymgK b4738 1212260 1212304 reverse protein YmgK b4738 ECK125276530 ymgL b4739 1212540 1212650 reverse protein YmgL b4739 ECK120003196 ycgX b1161 1212703 1213107 reverse DUF1398 domain-containing protein YcgX b1161 ECK120003197 bluR b1162 1213328 1214059 reverse DNA-binding transcriptional repressor BluR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 15556475,19240136, Weak b1162 ECK120003198 bluF b1163 1214264 1215475 reverse blue light- and temperature-regulated antirepressor BluF [EXP-IDA|W|Inferred from direct assay],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 15453820,19240136,21198648,21892488,31072500, Weak b1163 ECK120003199 ycgZ b1164 1215789 1216025 forward putative two-component system connector protein YcgZ [EXP-IMP|W|Inferred from mutant phenotype] 22783906,24012794,28713335, Weak b1164 ECK120003200 ymgA b1165 1216068 1216340 forward putative two-component system connector protein YmgA 28713335, b1165 ECK120003201 ariR b1166 1216369 1216635 forward putative two-component system connector protein AriR 28713335,31518447, b1166 ECK120003202 ymgC b1167 1216748 1216996 forward protein YmgC 28713335, b1167 ECK120003203 pdeG b1168 1217328 1218851 forward putative c-di-GMP phosphodiesterase PdeG 29018125, b1168 ECK120015304 ymgF b4520 1218983 1219201 forward inner membrane protein YmgF [EXP-IPI|W|Inferred from physical interaction],[EXP-IGI|W|Inferred from genetic interaction] 15774864,18978050,22885295,26074904, Weak b4520 ECK120003204 ycgH b4491 1219601 1222248 forward putative transporter component, N-terminal fragment 11544210, b1169,b1170,b4491 ECK120003206 ymgD b1171 1222305 1222634 reverse PF16456 family protein YmgD b1171 ECK120003207 ymgG b1172 1222644 1222988 reverse PF13436 family protein YmgG b1172 ECK120030073 ymgI b4593 1222990 1223163 reverse uncharacterized protein YmgI b4593 ECK120030074 ymgJ b4594 1223264 1223449 forward uncharacterized protein YmgJ b4594 ECK120016296 ycgI b4521 1223564 1223907 forward protein YcgI b1173,b4521 ECK120000591 minE b1174 1224279 1224545 reverse Z-ring positioning protein MinE [EXP-IDA-UNPURIFIED-PROTEIN-NH|W|Assay of unpurified protein expressed in its native host],[EXP-IGI|W|Inferred from genetic interaction] 11169104,14569005,1573903,1856170,2188963,2211499,23012351,23184489,24339757,24930948,25271375,26018614,26317492,2645057,26884160,28622374,28652337,29188788,29666276,30102292,30161173,30810919,32458918,33285025,33659532,6296039,6327636,7753804,7934847,8981994,9226273,9393861,9723924, Weak b1174 ECK120000590 minD b1175 1224549 1225361 reverse Z-ring positioning protein MinD [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IDA-UNPURIFIED-PROTEIN-NH|W|Assay of unpurified protein expressed in its native host],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 10540287,10931285,10966576,11158581,11169104,11254986,12093736,12368455,12688905,16936014,1836760,1856170,20543068,2137246,2149583,2188963,2211516,23184489,24339757,25271375,26317492,2645057,26739566,26884160,28652337,29188788,29666276,30102292,30161173,32199984,32458918,33285025,33288679,33659532,33881306,6296039,6327636,7928979,7934847,8432706,9171392,9226273, Strong b1175 ECK120000589 minC b1176 1225385 1226080 reverse Z-ring positioning protein MinC b1176 ECK120003209 ycgJ b1177 1226600 1226968 forward PF05666 family protein YcgJ b1177 ECK120003210 pliG b1178 1227071 1227472 reverse inhibitor of g-type lysozyme [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 20734102, Strong b1178 ECK125303714 ymgN b4816 1227368 1227427 forward protein YmgN b4816 ECK120003211 ycgL b1179 1227681 1228007 forward PF05166 family protein YcgL [EXP-IMP|W|Inferred from mutant phenotype] 16849790, Weak b1179 ECK120003212 ycgM b1180 1228079 1228738 forward putative isomerase/hydrolase b1180 ECK120003213 ycgN b1181 1228815 1229276 forward putative metal-chelating domain-containing protein YcgN b1181 ECK120003214 hlyE b1182 1229483 1230394 reverse hemolysin E [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 10027972,10383763,10858262,11053378,12008916,12949101,14532000,14996792,15133111,15292132,19111524,20511497,21896677,28073397,29491391,31048915,9421903,9812367, Weak b1182 ECK120002609 C0299 1230629 1230707 forward ECK120001046 umuD b1183 1230767 1231186 forward DNA polymerase V protein UmuD 33386487,6302271,6311684, b1183 ECK120001045 umuC b1184 1231186 1232454 forward DNA polymerase V catalytic protein 30087411,30916324,6302271,6311684, b1184 ECK120001360 dsbB b1185 1232500 1233030 reverse protein thiol:quinone oxidoreductase DsbB 16027117,17267399,18775700,21375236,23527473,25603425,26209678,28232484,28628094,7615498,8405447, b1185 ECK120001359 nhaB b1186 1233176 1234717 reverse Na antiporter NhaB 10207920,11779554,1331028,1332943,15371593,15601715,17635927,2555351,3034895,7592922,7737413,7822245,8017942,8381959,8588889,8616158, b1186 ECK120000275 fadR b1187 1234938 1235657 forward DNA-binding transcriptional dual regulator FadR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 11566998,1569108,2843809,8446033,9767562, Weak b1187 ECK120001471 ycgB b1188 1235709 1237241 reverse PF04293 family protein YcgB 19004873, b1188 ECK120001373 dadA b1189 1237571 1238869 forward D-amino acid dehydrogenase b1189 ECK120001374 dadX b1190 1238879 1239949 forward alanine racemase 2 b1190 ECK125276509 ymgM b4740 1240260 1240463 forward protein YmgM b4740 ECK120003215 cvrA b1191 1240335 1242071 reverse putative K antiporter b1191 ECK120003216 ldcA b1192 1242166 1243080 reverse murein tetrapeptide carboxypeptidase b1192 ECK120003217 emtA b1193 1243180 1243791 forward lytic murein transglycosylase E 11139297,15793119,29515200,32053772, b1193 ECK120003218 ycgR b1194 1243793 1244527 reverse flagellar brake protein YcgR [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IGI|W|Inferred from genetic interaction] 11031114,16920715,24203355,26195595, Weak b1194 ECK120003219 ymgE b1195 1244728 1244982 forward PF04226 family protein YmgE 24391520, b1195 ECK120003220 ycgY b1196 1245160 1245600 forward uncharacterized protein YcgY b1196 ECK120001006 treA b1197 1245679 1247376 reverse periplasmic trehalase 22036231, b1197 ECK120002261 dhaM b1198 1247696 1249114 reverse dihydroxyacetone kinase subunit M 11021910,11350937, b1198 ECK120003221 dhaL b1199 1249125 1249757 reverse dihydroxyacetone kinase subunit L 11021910,11350937,15771780,18632294,19189409, b1199 ECK120003222 dhaK b1200 1249768 1250838 reverse dihydroxyacetone kinase subunit K 11021910,11350937,15771780,18632294,19189409, b1200 ECK120003223 dhaR b1201 1251066 1252985 forward DNA-binding transcriptional dual regulator DhaR [EXP-IMP|W|Inferred from mutant phenotype] 15616579, Weak b1201 ECK120003224 ycgV b1202 1253085 1255952 reverse putative autotransporter adhesin YcgV 20447993,24391520, b1202 ECK120001370 ychF b1203 1256721 1257812 reverse redox-responsive ATPase YchF b1203 ECK120000776 pth b1204 1257929 1258513 reverse peptidyl-tRNA hydrolase b1204 ECK120001487 ychH b1205 1258791 1259069 forward stress-induced protein [EXP-IMP|W|Inferred from mutant phenotype] 19919618,24391520, Weak b1205 ECK120002255 dauA b1206 1259124 1260803 reverse aerobic C4-dicarboxylate transporter DauA 11574054,16397293, b1206 ECK120000765 prs b1207 1260928 1261875 reverse ribose-phosphate diphosphokinase b1207 ECK120001267 ispE b1208 1262026 1262877 reverse 4-(cytidine 5'-diphospho)-2--methyl-D-erythritol kinase b1208 ECK120001266 lolB b1209 1262877 1263500 reverse outer membrane lipoprotein LolB [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 10521496,15381108,19636844,19716823,24569999,32053772,33577754,34070637,9384574, Weak b1209 ECK120000420 hemA b1210 1263714 1264970 forward glutamyl-tRNA reductase 2548996, b1210 ECK120000752 prfA b1211 1265012 1266094 forward peptide chain release factor RF1 [EXP|W|Inferred from experiment],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 17932046,17996709,24136966,27297468,28301469,28741611,4879404, Weak b1211 ECK120002282 prmC b1212 1266094 1266927 forward protein-(glutamine-) methyltransferase 15024411, b1212 ECK120003225 ychQ b1213 1266924 1267316 forward SirB family protein YchQ b1213 ECK120001226 ychA b1214 1267320 1268129 forward transglutaminase-like/TPR repeat-containing protein b1214 ECK120000511 kdsA b1215 1268165 1269019 forward 3-deoxy-D--octulosonate 8-phosphate synthase 27173798,3531183,8778790, b1215 ECK120002655 ldrA b4419 1269168 1269275 reverse small toxic polypeptide LdrA [EXP|W|Inferred from experiment],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 12123448,24513967, Weak b4419 ECK120002656 rdlA b4420 1269323 1269389 forward putative antisense regulatory RNA RdlA [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 12123448, Weak b4420 ECK120002657 ldrB b4421 1269703 1269810 reverse small toxic polypeptide LdrB [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 12123448, Weak b4421 ECK120002658 rdlB b4422 1269858 1269923 forward putative antisense regulatory RNA RdlB [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 12123448,26469694, Weak b4422 ECK120002659 ldrC b4423 1270238 1270345 reverse small toxic polypeptide LdrC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 12123448, Weak b4423 ECK120002660 rdlC b4424 1270393 1270460 forward putative antisense regulatory RNA RdlC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 12123448,26469694, Weak b4424 ECK120001691 chaA b1216 1270749 1271849 reverse Na antiporter ChaA 10398838,12460671,17795541, b1216 ECK120002264 chaB b1217 1272119 1272349 forward putative cation transport regulator ChaB b1217 ECK120002265 chaC b1218 1272507 1273202 forward glutathione-specific γ-glutamylcyclotransferase b1218 ECK120002266 ychN b1219 1273246 1273599 reverse DsrE/F sulfur relay family protein YchN b1219 ECK120002267 ychO b1220 1273784 1275178 forward putative invasin YchO b1220 ECK120000636 narL b1221 1275179 1275829 reverse DNA-binding transcriptional dual regulator NarL [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 1482126,2066339,2157156,2648330,2649492,2657652,7643383,7699720,7854119,8098993,8501030, Weak b1221 ECK120000639 narX b1222 1275822 1277618 reverse sensor histidine kinase NarX b1222 ECK120000635 narK b1223 1277957 1279348 forward nitrate:nitrite antiporter NarK 3049531,6307982,9037773, b1223 ECK125303716 narS b4813 1279337 1279520 forward putative small regulatory RNA NarS [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 31863581, Weak b4813 ECK120000631 narG b1224 1279864 1283607 forward nitrate reductase A subunit α 15122898, b1224 ECK120000632 narH b1225 1283604 1285142 forward nitrate reductase A subunit β 1321049,8383531,8388253,8664273, b1225 ECK120000634 narJ b1226 1285139 1285849 forward nitrate reductase 1 molybdenum cofactor assembly chaperone [EXP|W|Inferred from experiment] Weak b1226 ECK120000633 narI b1227 1285849 1286526 forward nitrate reductase A subunit γ 1090591,12731882,9556558, b1227 ECK120003226 ychS b1228 1286709 1286984 forward putative uncharacterized protein YchS b1228 ECK120002661 rttR b4425 1287066 1287236 reverse small RNA RttR b4425 ECK120001005 tpr b1229 1287087 1287176 reverse protamine-like protein 12000793,1840671,20029369,7034960, b1229 ECK120002550 tyrV b1230 1287244 1287328 reverse tRNA-Tyr(GUA) [AS-TAS|W|Traceable author statement] 11946953,27551044,7033244, Weak b1230 ECK120002548 tyrT b1231 1287538 1287622 reverse tRNA-Tyr(GUA) [AS-TAS|W|Traceable author statement] 11946953,27551044,7033244, Weak b1231 ECK120001751 purU b1232 1287782 1288624 reverse formyltetrahydrofolate deformylase b1232 ECK120002022 ychJ b1233 1288674 1289132 reverse NTF2-like domain-containing protein YchJ b1233 ECK120002023 rssA b1234 1289245 1290150 forward putative patatin-like phospholipase RssA b1234 ECK120002024 rssB b1235 1290242 1291255 forward regulator of RpoS [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 12242500,12618449,12853450,12912910,15629914,16980505,17403784,18239914,18519731,20207164,22067413,25847996,30975721,8282700, Weak b1235 ECK120001290 galU b1236 1291457 1292365 forward UTP—glucose-1-phosphate uridylyltransferase b1236 ECK120000450 hns b1237 1292509 1292922 reverse DNA-binding transcriptional dual regulator H-NS [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IPI|W|Inferred from physical interaction],[EXP-IMP|W|Inferred from mutant phenotype] 11278074,15100692,1537791,15795232,15853876,16384714,16879983,1691451,16980475,17116239,17553830,17827501,17881364,2020545,2126011,2177526,2841565,3135462,6370250,7748941,7934818,8437561,8890170,9513262,9987132, Weak b1237 ECK120000983 tdk b1238 1293527 1294144 forward thymidine/deoxyuridine kinase b1238 ECK120003227 insZ b4573 1294426 1295322 reverse putative transposase InsZ b1239,b1240,b4573 ECK120000028 adhE b1241 1295446 1298121 reverse fused acetaldehyde-CoA dehydrogenase and iron-dependent alcohol dehydrogenasealdehyde/alcohol dehydrogenase AdhE 10572146,10601216,10753455,11131810,11741337,13382840,15781419,15988767,16187334,16313413,16739977,16849805,1744060,19055729,1999382,24077097,24584248,25178795,2695398,28480139,31497461,31989219,32414798,4301680,6998946,8423158, b1241 ECK125286396 ychT b4771 1298514 1298567 forward protein YchT b4771 ECK120001313 ychE b1242 1298598 1299245 forward MarC family putative inner membrane protein YchE b1242 ECK125229292 insH21 b4711 1299567 1300547 forward IS transposase and trans-activator b4711 ECK120000667 oppA b1243 1301182 1302813 forward oligopeptide ABC transporter periplasmic binding protein 10428855,10798552,1624428,17250759,21705338,34065855,9020114, b1243 ECK120000668 oppB b1244 1302899 1303819 forward murein tripeptide ABC transporter / oligopeptide ABC transporter inner membrane subunit OppB 31704256, b1244 ECK120000669 oppC b1245 1303834 1304742 forward murein tripeptide ABC transporter / oligopeptide ABC transporter inner membrane subunit OppC b1245 ECK120000670 oppD b1246 1304754 1305767 forward murein tripeptide ABC transporter / oligopeptide ABC transporter ATP binding subunit OppD b1246 ECK120000671 oppF b1247 1305764 1306768 forward murein tripeptide ABC transporter / oligopeptide ABC transporter ATP binding subunit OppF b1247 ECK120003228 yciU b1248 1306821 1307150 reverse DUF440 domain-containing protein YciU b1248 ECK120001556 clsA b1249 1307185 1308645 reverse cardiolipin synthase A 1323048,1625583,1661609,22125496,27760827,28815570,31235517,3918012,7047508,8262233, b1249 ECK120002602 yciY b4595 1308788 1308961 forward uncharacterized protein YciY b4595 ECK120001554 kch b1250 1309016 1310269 reverse K channel Kch b1250 ECK120001555 yciI b1251 1310569 1310865 reverse protein YciI b1251 ECK120001001 tonB b1252 1311089 1311808 forward Ton complex subunit TonB 1089064,11087740,11566987,11872715,12823822,12896813,14651622,14665631,15522863,15612934,15802653,17225063,17628143,1809832,2687240,27935943,30904393,350836,4929287,7665457,7997175,8039674,8316087,8316089,8631714,9150216,9353297, b1252 ECK120001105 yciA b1253 1311848 1312246 reverse acyl-CoA thioesterase YciA 24722906,30834961,32243749, b1253 ECK120001106 yciB b1254 1312351 1312890 reverse inner membrane protein 18180259,26032369,26454142, b1254 ECK120001107 yciC b1255 1312920 1313663 reverse putative inner membrane protein 24391520, b1255 ECK120001108 ompW b1256 1314020 1314658 forward outer membrane protein W [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 10348872,16372265, Weak b1256 ECK120001109 yciE b1257 1314718 1315224 reverse DUF892 domain-containing protein YciE b1257 ECK120001110 yciF b1258 1315270 1315770 reverse DUF892 domain-containing protein YciF 15583397, b1258 ECK120001111 yciG b1259 1315856 1316035 reverse stress-induced bacterial acidophilic repeat motifs-containing protein YciG b1259 ECK120001013 trpA b1260 1316416 1317222 reverse tryptophan synthase subunit α b1260 ECK120001014 trpB b1261 1317222 1318415 reverse tryptophan synthase subunit β b1261 ECK120001015 trpC b1262 1318427 1319788 reverse fused indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase b1262 ECK120001016 trpD b1263 1319789 1321384 reverse anthranilate synthase subunit TrpD b1263 ECK120001017 trpE b1264 1321384 1322946 reverse anthranilate synthase subunit TrpE b1264 ECK120001248 trpL b1265 1323038 1323082 reverse operon leader peptide [EXP-IDA|W|Inferred from direct assay] 10613855,27665603,28301469,34070637,7038627, Weak b1265 ECK120003229 yciV b1266 1323220 1324101 forward RNase AM 32343306, b1266 ECK120003230 yciO b1267 1324098 1324718 forward putative RNA-binding protein YciO b1267 ECK120003231 yciQ b1268 1324746 1326641 forward DUF2207 domain-containing protein YciQ b1268 ECK120002288 rluB b1269 1326852 1327727 forward 23S rRNA pseudouridine synthase 8871555, b1269 ECK120000126 btuR b1270 1327767 1328357 reverse cobinamide/cobalamin adenosyltransferase [EXP-IMP|W|Inferred from mutant phenotype] 2644187,7592411, Weak b1270 ECK120001695 yciK b1271 1328354 1329112 reverse putative oxidoreductase b1271 ECK120000945 sohB b1272 1329332 1330381 forward S49 peptidase family protein [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IGI|W|Inferred from genetic interaction] 1885549, Weak b1272 ECK120002411 yciN b1273 1330417 1330668 reverse protein YciN b1273 ECK120001002 topA b1274 1331048 1333645 forward DNA topoisomerase 1 b1274 ECK120000179 cysB b1275 1333855 1334829 forward DNA-binding transcriptional dual regulator CysB 1435253,1541275,2182030,3032952,3094306, b1275 ECK120016922 ymiA b4522 1335148 1335288 forward uncharacterized protein YmiA 26078445, b4522 ECK120016923 yciX b4523 1335291 1335458 forward uncharacterized protein YciX 26078445, b4523 ECK125276518 ymiC b4741 1335572 1335667 forward protein YmiC b4741 ECK120001296 acnA b1276 1335831 1338506 forward aconitate hydratase 1 1541275,1838390, b1276 ECK120001302 ribA b1277 1338570 1339160 reverse GTP cyclohydrolase 2 b1277 ECK120000697 pgpB b1278 1339330 1340094 forward phosphatidylglycerophosphatase B b1278 ECK120003232 lapA b1279 1340243 1340551 forward lipopolysaccharide assembly protein A [EXP-IPI|W|Inferred from physical interaction] 24722986,34070637,34809459, Weak b1279 ECK120002356 lapB b1280 1340558 1341727 forward lipopolysaccharide assembly protein B [EXP-IDA-UNPURIFIED-PROTEIN-NH|W|Assay of unpurified protein expressed in its native host],[EXP-IPI|W|Inferred from physical interaction],[EXP-IGI|W|Inferred from genetic interaction] 24266962,24391520,24722986,26190574,33990910, Weak b1280 ECK120000800 pyrF b1281 1341921 1342658 forward orotidine-5'-phosphate decarboxylase b1281 ECK120001112 yciH b1282 1342658 1342984 forward putative translation factor [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IGI|W|Inferred from genetic interaction] 10497266,27732863, Weak b1282 ECK120000672 osmB b1283 1343110 1343328 reverse osmotically-inducible lipoprotein OsmB 28416660,32053772, b1283 ECK120003233 yciT b1284 1343597 1344346 reverse DNA-binding transcriptional dual regulator YciT [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 10734204,15556475,16451192, Weak b1284 ECK120030075 yciZ b4596 1344436 1344609 reverse UPF0509 family protein YciZ b4596 ECK125286407 ymiD b4772 1344647 1344775 forward protein YmiD b4772 ECK120003234 pdeR b1285 1344757 1346742 reverse cyclic di-GMP phosphodiesterase PdeR 28913868,29997584, b1285 ECK125240986 ymiB b4672 1346796 1346900 forward putative protein YmiB 34809459, b4672 ECK120001568 rnb b1286 1346978 1348912 reverse RNase II b1286 ECK120003235 yciW b1287 1348980 1350107 reverse putative peroxidase YciW b1287 ECK120001482 fabI b1288 1350251 1351039 reverse enoyl-[acyl-carrier-protein] reductase b1288 ECK120003236 ycjD b1289 1351407 1351760 reverse DUF559 domain-containing protein YcjD b1289 ECK120002184 sapF b1290 1351828 1352634 reverse putrescine ABC exporter ATP binding protein SapF b1290 ECK120002183 sapD b1291 1352636 1353628 reverse putrescine ABC exporter ATP binding protein SapD [EXP-IDA-UNPURIFIED-PROTEIN-NH|W|Assay of unpurified protein expressed in its native host],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 11700350,1987159,20333436, Weak b1291 ECK120002674 sapC b1292 1353628 1354518 reverse putrescine ABC exporter membrane protein SapC b1292 ECK120002675 sapB b1293 1354505 1355470 reverse putrescine ABC exporter membrane subunit SapB 31438868, b1293 ECK120002676 sapA b1294 1355467 1357110 reverse putative periplasmic binding protein SapA 31438868, b1294 ECK120003237 ymjA b1295 1357423 1357668 reverse DUF2543 domain-containing protein YmjA 24391520, b1295 ECK120003238 puuP b1296 1357802 1359187 reverse putrescine:H symporter PuuP b1296 ECK125276527 ymjE b4742 1359177 1359341 reverse protein YmjE b4742 ECK120003239 puuA b1297 1359490 1360908 reverse glutamate-putrescine ligase b1297 ECK120003240 puuD b1298 1361120 1361884 forward γ-glutamyl-γ-aminobutyrate hydrolase b1298 ECK120002286 puuR b1299 1361911 1362468 forward DNA-binding transcriptional repressor PuuR [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 15556475,15590624, Weak b1299 ECK120000033 puuC b1300 1362743 1364230 forward γ-glutamyl-γ-aminobutyraldehyde dehydrogenase b1300 ECK120001754 puuB b1301 1364232 1365512 forward γ-glutamylputrescine oxidase [EXP|W|Inferred from experiment] 15590624, Weak b1301 ECK120003241 puuE b1302 1365550 1366815 forward 4-aminobutyrate aminotransferase PuuE 26476527,26667817,28190099, b1302 ECK120002219 pspF b1303 1366935 1367912 reverse DNA-binding transcriptional dual regulator PspF b1303 ECK120000767 pspA b1304 1368079 1368747 forward phage shock protein A [EXP-IDA|W|Inferred from direct assay] 12079332,19124575,19614590,20545840,20595257,20830338,21259006,26319873, Weak b1304 ECK120000768 pspB b1305 1368801 1369025 forward phage shock protein B [EXP|W|Inferred from experiment],[AS|W|Author statement] 14594833,1717346, Weak b1305 ECK120000769 pspC b1306 1369025 1369384 forward phage shock protein C [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 15556475,1717346,19614590,19682256,21059793,21259006,21569396,22689583,24361331, Weak b1306 ECK120000770 pspD b1307 1369393 1369614 forward phage shock protein D [EXP-IEP|W|Inferred from expression pattern] 1712397, Weak b1307 ECK120000771 pspE b1308 1369689 1370003 forward thiosulfate sulfurtransferase PspE 31253770, b1308 ECK120003242 ycjM b1309 1370216 1371895 forward glucosylglycerate phosphorylase 24926622,26282760, b1309 ECK120003243 ycjN b1310 1371909 1373201 forward putative ABC transporter periplasmic binding protein YcjN 31438868, b1310 ECK120003244 ycjO b1311 1373222 1374103 forward putative ABC transporter membrane subunit YcjO 31438868, b1311 ECK120003245 ycjP b1312 1374090 1374932 forward putative ABC transporter membrane subunit YcjP 31438868, b1312 ECK120003246 ycjQ b1313 1374963 1376015 forward D-guloside 3-dehydrogenase b1313 ECK120003247 ycjR b1314 1376034 1376822 forward 3-dehydro-D-guloside 4-epimerase b1314 ECK120003248 ycjS b1315 1376832 1377887 forward D-glucoside 3-dehydrogenase b1315 ECK120003249 ycjT b1316 1377884 1380151 forward kojibiose phosphorylase b1316 ECK120003250 ycjU b1317 1380148 1380807 forward β-phosphoglucomutase 25848029, b1317 ECK120003251 ycjV b1318 1380821 1381789 forward putative ABC transporter ATP-binding protein YcjV b1318 ECK120016297 ymjB b4524 1381789 1381902 forward hypothetical protein YmjB 31438868, b4524 ECK120003252 ompG b1319 1381947 1382852 forward outer membrane porin G 11009596,11114248,12899633,16138308,18473482,18942851,2473977,25950964,30271910,9721282, b1319 ECK120003253 ycjW b1320 1382963 1383961 reverse DNA-binding transcriptional repressor YcjW [EXP-IDA|W|Inferred from direct assay],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 10734204,15556475,24391520,31253770, Weak b1320 ECK120003254 ycjX b1321 1384117 1385514 forward DUF463 domain-containing protein YcjX b1321 ECK120002412 ycjF b1322 1385511 1386572 forward DUF697 domain-containing inner membrane protein YcjF b1322 ECK120001031 tyrR b1323 1386720 1388261 forward DNA-binding transcriptional dual regulator TyrR [EXP-IMP|W|Inferred from mutant phenotype],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 15049824,1943694,3001057,4887504,8106498,8444880,8449883, Strong b1323 ECK120003255 tpx b1324 1388305 1388811 reverse lipid hydroperoxide peroxidase b1324 ECK120003256 ycjG b1325 1388930 1389895 forward L-Ala-D/L-Glu epimerase 11747447,18020459, b1325 ECK120003257 mpaA b1326 1389870 1390598 reverse murein tripeptide amidase A b1326 ECK120016298 ymjC b4525 1390680 1390862 reverse putative uncharacterized protein YmjC b4525 ECK120048857 ymjD b4673 1390868 1390933 reverse uncharacterized protein YmjD b4673 ECK120003258 ycjY b1327 1390933 1391853 reverse putative hydrolase YcjY 24391520, b1327 ECK120003259 pgrR b1328 1391991 1392890 forward DNA-binding transcriptional repressor PgrR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IDA-PART-PURIFIED-PROTEIN-NH|W|Assay of protein partially-purified from its native host] 10734204,15556475,23301696, Weak b1328 ECK120003260 mppA b1329 1393227 1394840 forward murein tripeptide ABC transporter periplasmic binding protein 10438753,12562820, b1329 ECK120003261 ynaI b1330 1394891 1395922 reverse small conductance mechanosensitive channel YnaI b1330 ECK120003262 insH4 b1331 1396112 1397092 forward IS transposase and trans-activator b1331 ECK120003263 ynaJ b1332 1397365 1397622 forward DUF2534 domain-containing protein YnaJ b1332 ECK120001222 uspE b1333 1397672 1398622 reverse universal stress protein E [EXP-IMP|W|Inferred from mutant phenotype] 16159758,24061173,31578056, Weak b1333 ECK120000319 fnr b1334 1398774 1399526 reverse DNA-binding transcriptional dual regulator FNR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IDA-PART-PURIFIED-PROTEIN-NH|W|Assay of protein partially-purified from its native host],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 11407111,11771123,11931557,17293415,1854188,1957353,2181237,2248796,2677602,6292868,7747934,796407,8119409,8412675,8588737,8871401,9230919,9282732,9990723, Strong b1334 ECK120000661 ogt b1335 1399721 1400236 reverse methylated-DNA—[protein]-cysteine -methyltransferase 1600955,17951114,1986273,1993655,2002008,23446177,2682522,2685744,2690020,2825131,3283737,3889845,7728961,8195077,8202083,8512805,8519412,9118970,9464319,9717173,9800196, b1335 ECK120002401 abgT b1336 1400247 1401773 reverse symporter b1336 ECK120003264 abgB b1337 1401810 1403255 reverse -aminobenzoyl-glutamate hydrolase subunit B b1337 ECK120003265 abgA b1338 1403255 1404565 reverse -aminobenzoyl-glutamate hydrolase subunit A b1338 ECK120003266 abgR b1339 1404741 1405649 forward putative LysR-type DNA-binding transcriptional regulator AbgR [COMP-HINF|W|Inferred by a human based on computational evidence] 9829935, Weak b1339 ECK120002610 mcaS b4426 1405658 1405751 reverse small regulatory RNA McaS [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 22250746,22289118,22414234,30287822,30799856,34067197, Weak b4426 ECK120003267 smrA b1340 1405979 1406542 forward DNA endonuclease SmrA 24516157, b1340 ECK120003268 dgcM b1341 1406563 1407795 reverse diguanylate cyclase DgcM b1341 ECK125286418 ynaN b4773 1407989 1408036 forward protein YnaN b4773 ECK120003269 zntB b1342 1408050 1409033 forward Zn symporter 24391520, b1342 ECK125095415 fnrS b4699 1409129 1409250 forward small regulatory RNA FnrS [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 20070527,20075074, Weak b4699 ECK120002611 ynaL b4743 1409308 1409481 forward protein YnaL b4743 ECK120000204 dbpA b1343 1409511 1410884 forward ATP-dependent RNA helicase DbpA [EXP-IDA|W|Inferred from direct assay],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 19734347,21437710,22713314,25579585,33277687,8253085,8524828, Weak b1343 ECK120003270 ttcA b1344 1411013 1411948 reverse tRNA cytosine 2-sulfurtransferase TtcA b1344 ECK120003271 intR b1345 1412000 1413235 reverse Rac prophage; putative integrase b1345 ECK120003272 xisR b1346 1413237 1413452 reverse Rac prophage; excisionase [EXP-IMP|W|Inferred from mutant phenotype] 26530864, Weak b1346 ECK120001830 rcbA b1347 1413531 1413740 reverse Rac prophage; double-strand break reduction protein [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 22343303, Weak b1347 ECK125165375 ralA b4714 1413556 1413734 forward Rac prophage; small regulatory RNA antitoxin RalA [EXP-IMP|W|Inferred from mutant phenotype] 24748661, Weak b4714 ECK120001829 ralR b1348 1413733 1413927 reverse Rac prophage; endodeoxyribonuclease toxin RalR [EXP-IDA|W|Inferred from direct assay],[EXP-IGI|W|Inferred from genetic interaction] 16237019,16677300,24748661,4562392,6264133,7476171,8244937, Weak b1348 ECK120001828 recT b1349 1413984 1414793 reverse Rac prophage; recombinase RecT [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IGI|W|Inferred from genetic interaction] 12169595,12718760,16237019,28096446,8125297,8159725,8244937,8416902, Weak b1349 ECK120000818 recE b1350 1414786 1417386 reverse Rac prophage; exonuclease VIII, ds DNA exonuclease, 5' --> 3' specific 28096446, b1350 ECK120000804 racC b1351 1417488 1417763 reverse Rac prophage; protein RacC b1351 ECK120002628 ydaE b4526 1417838 1418008 reverse Rac prophage; zinc-binding protein 24391520,26774489, b4526 ECK120002054 kilR b1352 1418008 1418229 reverse Rac prophage; inhibitor of FtsZ [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 8752325, Weak b1352 ECK125303713 kilS b4833 1418405 1418502 reverse Rac prophage; small RNA KilS b4833 ECK120002053 sieB b1353 1418671 1419159 forward Rac prophage; phage superinfection exclusion protein b1353 ECK120016300 ydaF b4527 1419156 1419311 reverse Rac prophage; DUF1391 domain-containing protein YdaF b4527 ECK120003273 Phantom Gene b1354 1419168 1419344 forward b1354 ECK120003274 ydaG b1355 1419322 1419456 reverse Rac prophage; uncharacterized protein YdaG b1355 ECK120003275 racR b1356 1419765 1420241 reverse Rac prophage; DNA-binding transcriptional repressor RacR [COMP-HINF|W|Inferred by a human based on computational evidence],[EXP-IEP|W|Inferred from expression pattern],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10734204,15556475,29205228,29205229, Strong b1356 ECK120003276 ydaS b1357 1420365 1420661 forward Rac prophage; toxin YdaS [EXP-IMP|W|Inferred from mutant phenotype] 29205228, Weak b1357 ECK120003277 ydaT b1358 1420684 1421106 forward Rac prophage; protein YdaT [EXP-IMP|W|Inferred from mutant phenotype] 29205229, Weak b1358 ECK120003278 ydaU b1359 1421119 1421976 forward Rac prophage; DUF1376 domain-containing protein YdaU b1359 ECK120003279 ydaV b1360 1421983 1422729 forward Rac prophage; putative ATP-binding protein YdaV b1360 ECK120003280 ydaW b1361 1422752 1423312 forward Rac prophage; putative uncharacterized protein YdaW b1361 ECK120003281 rzpR b1362 1423345 1423644 forward Rac prophage; putative endopeptidase RzpR b1362 ECK120016301 rzoR b4528 1423400 1423585 forward Rac prophage; putative prophage outer membrane lipoprotein RzoR 32053772, b4528 ECK120001009 trkG b1363 1423782 1425239 forward Rac prophage; K transporter TrkG 11092250,15205426,20333436,9798786, b1363 ECK120003282 b1364 b1364 1425178 1425459 forward ECK120003283 ynaK b1365 1425377 1425640 forward Rac prophage; ParB-like nuclease domain-containing protein YnaK b1365 ECK120003284 ydaY b1366 1425621 1425980 forward Rac prophage; putative uncharacterized protein YdaY b1366 ECK120003285 Phantom Gene b1367 1426055 1426288 forward b1367 ECK120003286 ynaA b1368 1426454 1427482 forward Rac prophage; putative prophage tail length tape measure domain-containing protein YnaA b1368 ECK120003288 insH5 b1370 1427746 1428726 reverse Rac prophage; IS transposase and trans-activator b1370 ECK120003290 stfR b1372 1429049 1432411 forward Rac prophage; putative prophage side tail fiber protein StfR [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 16397293, Weak b1372 ECK120003291 tfaR b1373 1432411 1432986 forward Rac prophage; putative tail fiber assembly protein TfaR b1373 ECK120003292 pinR b1374 1433084 1433674 reverse Rac prophage; putative site-specific recombinase b1374 ECK120003293 ynaE b1375 1433991 1434224 reverse Rac prophage; uncharacterized protein YnaE b1375 ECK125276506 ynaM b4744 1434293 1434406 reverse Rac prophage; protein YnaM b4744 ECK125240972 ttcC b4638 1434958 1435008 reverse putative tRNA 2-thiocytidine (s(2)C32) synthase b4638 ECK120003294 uspF b1376 1435185 1435619 reverse universal stress protein F [EXP-IMP|W|Inferred from mutant phenotype] 16159758,27616205, Weak b1376 ECK120003295 ompN b1377 1435760 1436893 reverse outer membrane porin N b1377 ECK120002612 micC b4427 1437121 1437231 forward small regulatory RNA MicC [EXP-IEP|W|Inferred from expression pattern],[EXP-IGI|W|Inferred from genetic interaction] 12069726,15466019,17264113,20068355, Weak b4427 ECK120003296 ydbK b1378 1437260 1440784 reverse putative pyruvate-flavodoxin oxidoreductase b1378 ECK120016302 ydbJ b4529 1441058 1441324 forward DUF333 domain-containing protein YdbJ b4529 ECK120003297 hslJ b1379 1441321 1441743 reverse lipoprotein implicated in Novobiocin resistance 15174130,22534293, b1379 ECK120002700 ldhA b1380 1441854 1442843 reverse D-lactate dehydrogenase b1380 ECK120003298 ydbH b1381 1443051 1445690 forward putative phospholipid transport factor YdbH [EXP-IGI|W|Inferred from genetic interaction] 34781743, Weak b1381 ECK120003299 ynbE b1382 1445687 1445872 forward lipoprotein YnbE 21695201,32053772, b1382 ECK120003300 ydbL b1383 1445880 1446206 forward DUF1318 domain-containing protein YdbL b1383 ECK120003301 feaR b1384 1446378 1447283 reverse DNA-binding transcriptional activator FeaR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 8631685,9043126, Weak b1384 ECK120004448 feaB b1385 1447519 1449018 forward phenylacetaldehyde dehydrogenase b1385 ECK120002427 tynA b1386 1449076 1451349 reverse copper-containing amine oxidase 8647101, b1386 ECK120003302 paaZ b1387 1451597 1453642 reverse fused 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase and oxepin-CoA hydrolase b1387 ECK120003303 paaA b1388 1453927 1454856 forward phenylacetyl-CoA 1,2-epoxidase, monooxygenase subunit b1388 ECK120003304 paaB b1389 1454868 1455155 forward phenylacetyl-CoA 1,2-epoxidase subunit B b1389 ECK120003305 paaC b1390 1455164 1455910 forward phenylacetyl-CoA 1,2-epoxidase, structural subunit b1390 ECK120003306 paaD b1391 1455925 1456422 forward phenylacetate degradation protein b1391 ECK120003307 paaE b1392 1456430 1457500 forward phenylacetyl-CoA 1,2-epoxidase, reductase subunit b1392 ECK120003308 paaF b1393 1457497 1458264 forward putative 2,3-dehydroadipyl-CoA hydratase [EXP-IMP|W|Inferred from mutant phenotype] 12846838,15137080, Weak b1393 ECK120003309 paaG b1394 1458264 1459052 forward putative ring 1,2-epoxyphenylacetyl-CoA isomerase (oxepin-CoA forming) [EXP-IMP|W|Inferred from mutant phenotype] 12846838,15137080, Weak b1394 ECK120003310 paaH b1395 1459054 1460481 forward 3-hydroxyadipyl-CoA dehydrogenase 15137080, b1395 ECK120003311 paaI b1396 1460471 1460893 forward phenylacetyl-CoA thioesterase b1396 ECK120003312 paaJ b1397 1460893 1462098 forward β-ketoadipyl-CoA thiolase b1397 ECK120003313 paaK b1398 1462125 1463438 forward phenylacetate-CoA ligase 8472917, b1398 ECK120003314 paaX b1399 1463539 1464489 forward DNA-binding transcriptional repressor PaaX 10766858,11243806,9748275, b1399 ECK120003315 paaY b1400 1464471 1465061 forward 2-hydroxycyclohepta-1,4,6-triene-1-carboxyl-CoA thioesterase b1400 ECK120048858 ynbG b4674 1465165 1465230 reverse uncharacterized protein YnbG b4674 ECK120003317 insD2 b1402 1467921 1468826 reverse IS2 insertion element protein InsB b1402 ECK120023918 insCD2 1467921 1469149 reverse IS2 element transposase InsAB' ECK120003318 insC2 b1403 1468784 1469149 reverse IS2 insertion element repressor InsA b1403 ECK120003319 insI2 b1404 1469358 1470509 forward IS30 transposase [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 9303555, Weak b1404 ECK120001280 pdxI b1406 1474221 1475081 forward pyridoxal reductase 32253339, b1406 ECK120001281 ydbD b1407 1475144 1477450 forward DUF2773 domain-containing protein YdbD [EXP-IGI|W|Inferred from genetic interaction] 17846588, Weak b1407 ECK120003320 ynbA b1408 1477621 1478226 forward CDP-alcohol phosphatidyltransferase domain-containing protein YnbA 28815570, b1408 ECK120003321 ynbB b1409 1478226 1479122 forward putative CDP-diglyceride synthase 24391520,34809459, b1409 ECK120003322 ynbC b1410 1479138 1480895 forward hydrolase/methyltransferase domain-containing protein YnbC b1410 ECK120003323 ynbD b1411 1480909 1482201 forward phosphatase domain-containing protein YnbD b1411 ECK120003324 azoR b1412 1482255 1482860 reverse FMN dependent NADH:quinone oxidoreductase 16511052,18440871,20540494,25323408, b1412 ECK120003325 hrpA b1413 1483061 1486963 forward ATP-dependent 3'→5' RNA helicase HrpA 29769716, b1413 ECK120002014 ydcF b1414 1487235 1488035 forward DUF218 domain-containing protein YdcF b1414 ECK120000032 aldA b1415 1488232 1489671 forward aldehyde dehydrogenase A 26336892, b1415 ECK120004456 gapC b4493 1489713 1490713 reverse glyceraldehyde-3-phosphate dehydrogenase b1416,b1417,b4493 ECK120000167 cybB b1418 1490902 1491432 forward superoxide oxidase 2836696, b1418 ECK120030076 rydC b4597 1491442 1491506 reverse small regulatory RNA RydC [EXP-IMP|W|Inferred from mutant phenotype] 15618228,30700509,31308070, Weak b4597 ECK120001198 ydcA b1419 1491677 1491850 forward protein YdcA b1419 ECK125286394 yncP b4774 1491876 1491944 forward protein YncP b4774 ECK120002662 hokB b4428 1491922 1492071 reverse toxin HokB [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 10361310,11014799,16751270,17065468,26051177,30108166, Weak b4428 ECK120003326 mokB b1420 1491962 1492129 reverse putative regulatory protein MokB 11014799,16751270, b1420 ECK120002663 sokB b4429 1492119 1492175 forward putative small regulatory RNA antitoxin SokB [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10361310,16751270,17065468, Weak b4429 ECK120001007 trg b1421 1492470 1494110 forward methyl-accepting chemotaxis protein Trg b1421 ECK120003327 ydcI b1422 1494148 1495071 reverse DNA-binding transcriptional dual regulator YdcI [EXP-IDA-PURIFIED-PROTEIN-HH|S|Assay of protein purified to homogeneity from a heterologous host],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IPI|W|Inferred from physical interaction] 10734204,15556475,24962596,30137486, Strong b1422 ECK120003328 ydcJ b1423 1495288 1496631 forward DUF1338 domain-containing protein YdcJ b1423 ECK120002405 opgD b1424 1496856 1498511 forward glucans biosynthesis protein D [EXP-IMP|W|Inferred from mutant phenotype] 15175282, Weak b1424 ECK120003329 Phantom Gene b1425 1498432 1498635 reverse b1425 ECK120002408 ydcH b1426 1498651 1498875 forward DUF465 domain-containing protein YdcH b1426 ECK120000844 rimL b1427 1498938 1499477 forward ribosomal-protein-L12-serine -acetyltransferase b1427 ECK120003330 ydcK b1428 1499469 1500449 reverse putative acyltransferase YdcK 24391520, b1428 ECK120001813 tehA b1429 1500573 1501565 forward tellurite resistance protein 31438868, b1429 ECK120001814 tehB b1430 1501562 1502155 forward tellurite methyltransferase b1430 ECK120003331 ydcL b1431 1502457 1503125 forward DUF3313 domain-containing lipoprotein YdcL 21695201,32053772, b1431 ECK120026448 yncK b4578 1503218 1503649 reverse b4530,b4531,b4578 ECK120003332 insQ b1432 1503657 1504865 forward putative accessory protein InsQ for insertion sequence element IS609 b1432 ECK120003333 ydcO b1433 1504905 1506080 reverse putative transport protein YdcO 31438868,9529885, b1433 ECK120003334 sutR b1434 1506172 1506708 forward DNA-binding transcriptional dual regulator SutR [EXP-IEP|W|Inferred from expression pattern],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10734204,15556475,24391520,25406449, Strong b1434 ECK120003335 rlhA b1435 1506781 1508742 forward 23S rRNA 5-hydroxycytidine C2501 synthase [EXP-IMP|W|Inferred from mutant phenotype] 29069499, Weak b1435 ECK120003336 yncJ b1436 1508834 1509064 reverse DUF2554 domain-containing protein YncJ b1436 ECK120003337 Phantom Gene b1437 1509250 1509447 reverse b1437 ECK120016303 hicA b4532 1509286 1509462 forward mRNA interferase toxin HicA [EXP-IMP|W|Inferred from mutant phenotype] 19060138,28876228,31495532, Weak b4532 ECK120003338 hicB b1438 1509508 1509924 forward antitoxin of the HicA-HicB toxin-antitoxin system / DNA-binding transcriptional repressor HicB [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 15556475,17172327,19060138, Weak b1438 ECK120003339 ydcR b1439 1510003 1511409 forward fused putative DNA-binding transcriptional regulator/putative aminotransferase YdcR [COMP-HINF|W|Inferred by a human based on computational evidence],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475,20480162, Weak b1439 ECK120003340 ydcS b1440 1511654 1512799 forward putative ABC transporter periplasmic binding protein / polyhydroxybutyrate synthase 15576800,26774489,31438868, b1440 ECK120003341 ydcT b1441 1512817 1513830 forward putative ABC transporter ATP-binding protein YdcT 18634750,31438868, b1441 ECK120003342 ydcU b1442 1513831 1514772 forward putative ABC transporter membrane subunit YdcU 31438868, b1442 ECK120003343 ydcV b1443 1514762 1515556 forward putative ABC transporter membrane subunit YdcV 18634750,31438868, b1443 ECK120003344 patD b1444 1515578 1517002 forward γ-aminobutyraldehyde dehydrogenase 27289384,27800627,30425699,30498244, b1444 ECK120002598 yncL b4598 1517099 1517194 reverse uncharacterized protein YncL b4598 ECK120003345 ortT b1445 1517389 1517562 forward orphan toxin OrtT b1445 ECK120003346 ydcY b1446 1517648 1517881 forward DUF2526 domain-containing protein YdcY b1446 ECK120003347 ydcZ b1447 1517882 1518331 reverse putative inner membrane protein YdcZ 31438868, b1447 ECK120003348 mnaT b1448 1518328 1518846 reverse L-amino acid N-acyltransferase b1448 ECK120003349 curA b1449 1519027 1520064 forward NADPH-dependent curcumin/dihydrocurcumin reductase 21467222, b1449 ECK120003350 mcbR b1450 1520262 1520927 forward DNA-binding transcriptional dual regulator McbR [EXP-IEP|W|Inferred from expression pattern],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ],[EXP-IDA-PART-PURIFIED-PROTEIN-HH|W|Assay of protein partially-purified from a heterologous host] 15556475,18309357,20713450, Weak b1450 ECK120003351 yncD b1451 1520963 1523065 reverse putative TonB-dependent outer membrane receptor [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 12192075, Weak b1451 ECK120003352 yncE b1452 1523307 1524368 forward PQQ-like domain-containing protein YncE 27904885,31186336, b1452 ECK120003353 ansP b1453 1524481 1525980 reverse L-asparagine transporter b1453 ECK120003354 yncG b1454 1526247 1526864 forward putative glutathione -transferase YncG 14635120,17018556, b1454 ECK120003355 yncH b1455 1526940 1527152 forward DUF5445 domain-containing protein YncH b1455 ECK120000008 rhsE b1456 1527890 1529938 forward RhsE protein in rhs element 6086936, b1456 ECK120001696 ydcD b1457 1529922 1530404 forward uncharacterized protein YdcD 24391520, b1457 ECK125276516 yncO b4745 1530319 1530504 reverse protein YncO b4745 ECK120003356 yncI b1459 1530586 1531639 forward putative transposase YncI b1458,b1459 ECK120001480 ydcC b1460 1531816 1532952 forward H repeat-associated putative transposase YdcC b1460 ECK120001697 pptA b1461 1533052 1533285 forward tautomerase PptA b1461 ECK120003358 yddH b1462 1533282 1533851 reverse flavin reductase-like protein YddH b1462 ECK120003359 nhoA b1463 1534024 1534869 forward arylamine -acetyltransferase b1463 ECK120001757 yddE b1464 1534965 1535858 reverse PF02567 family protein YddE b1464 ECK120000637 narV b1465 1535937 1536617 reverse nitrate reductase Z subunit γ b1465 ECK120000638 narW b1466 1536614 1537309 reverse NarW, putative private chaperone for NarZ nitrate reductase subunit b1466 ECK120000640 narY b1467 1537309 1538853 reverse nitrate reductase Z subunit β b1467 ECK120000641 narZ b1468 1538850 1542590 reverse nitrate reductase Z subunit α b1468 ECK120002052 narU b1469 1542672 1544060 reverse nitrate/nitrite transporter NarU b1469 ECK120003360 yddJ b1470 1544384 1544719 reverse uncharacterized protein YddJ b1470 ECK120003361 yddK b1471 1544758 1545714 reverse leucine-rich repeat domain-containing protein YddK b1471 ECK120003362 yddL b1472 1545738 1546028 reverse putative uncharacterized protein YddL b1472 ECK120002370 yddG b1473 1546288 1547169 reverse amino acid exporter YddG 12410826,15919996,17025177,17164287,21531828,31438868, b1473 ECK120001205 fdnG b1474 1547401 1550448 forward formate dehydrogenase N subunit α b1474 ECK120001206 fdnH b1475 1550461 1551345 forward formate dehydrogenase N subunit β 20406421, b1475 ECK120001207 fdnI b1476 1551338 1551991 forward formate dehydrogenase N subunit γ b1476 ECK120002613 C0362 1552001 1552386 forward ECK120003363 yddM b1477 1552398 1552682 reverse DNA-binding transcriptional regulator YddM [EXP-IPI|W|Inferred from physical interaction] 30137486, Weak b1477 ECK120003364 adhP b1478 1552828 1553838 reverse ethanol dehydrogenase / alcohol dehydrogenase b1478 ECK120000937 maeA b1479 1553972 1555669 reverse malate dehydrogenase (oxaloacetate-decarboxylating) 16849805,17880710,17951436,18045419,18679018,21272045,21324682,22588847,23128557,23957584,24103861,24449451,26878126,29034624, b1479 ECK120001464 sra b1480 1555826 1555963 reverse ribosome-associated protein Sra 10094780,28114288, b1480 ECK120003365 bdm b1481 1556065 1556280 reverse biofilm-dependent modulation protein [EXP-IMP|W|Inferred from mutant phenotype] 21133991,25398323,32094588, Weak b1481 ECK120000673 osmC b1482 1556625 1557056 forward osmotically inducible peroxiredoxin OsmC b1482 ECK120003366 ddpF b1483 1557112 1558038 reverse putative D,D-dipeptide ABC transporter ATP-binding subunit DdpF b1483 ECK120003367 ddpD b1484 1558031 1559017 reverse putative D,D-dipeptide ABC transporter ATP-binding subunit DdpD b1484 ECK120003368 ddpC b1485 1559014 1559910 reverse putative D,D-dipeptide ABC transporter membrane subunit DdpC b1485 ECK120003369 ddpB b1486 1559907 1560929 reverse putative D,D-dipeptide ABC transporter membrane subunit DdpB b1486 ECK120003370 ddpA b1487 1560931 1562481 reverse putative D,D-dipeptide ABC transporter periplasmic binding protein 20700606, b1487 ECK120003371 ddpX b1488 1562495 1563076 reverse D-alanyl-D-alanine dipeptidase b1488 ECK120003372 dosP b1489 1563334 1565733 reverse oxygen-sensing c-di-GMP phosphodiesterase DosP b1489 ECK120003373 dosC b1490 1565758 1567140 reverse diguanylate cyclase DosC b1490 ECK125276525 yddY b4746 1567178 1567219 reverse protein YddY b4746 ECK120003374 digH b1491 1567504 1568823 reverse divisome localized glycosyl hydrolase 32053772, b1491 ECK120003375 gadC b1492 1568954 1570489 reverse L-glutamate:4-aminobutyrate antiporter 10383761,16980449,7608084, b1492 ECK120001446 gadB b1493 1570645 1572045 reverse glutamate decarboxylase B 10383761,1522060,32346014,7608084, b1493 ECK120001683 pqqL b1494 1572407 1575202 reverse periplasmic metalloprotease [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 21141474,31613892, Weak b1494 ECK120001682 yddB b1495 1575247 1577619 reverse putative TonB-dependent receptor YddB [EXP-IDA|W|Inferred from direct assay] 31613892, Weak b1495 ECK120001681 yddA b1496 1577657 1579342 reverse ABC transporter family protein YddA 31438868,32347079, b1496 ECK125276504 yneP b4747 1579545 1579667 forward protein YneP b4747 ECK120003376 ydeM b1497 1579633 1580790 reverse putative anaerobic sulfatase maturation enzyme YdeM [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15556475,16766528, Weak b1497 ECK120003377 ydeN b1498 1580842 1582524 reverse putative sulfatase YdeN b1498 ECK120003378 ydeO b1499 1582926 1583687 reverse DNA-binding transcriptional dual regulator YdeO [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 12399493,12694615,15489450,20603130,25375160,9409145, Strong b1499 ECK120003379 safA b1500 1583762 1583959 reverse two-component system connector SafA [EXP-IDA|W|Inferred from direct assay],[EXP-IPI|W|Inferred from physical interaction] 16385049,17998538,21193607,34070637, Weak b1500 ECK120003380 ydeP b1501 1584207 1586486 reverse putative oxidoreductase YdeP [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 12399493,12694615, Weak b1501 ECK120003381 ydeQ b1502 1586820 1587734 reverse putative fimbrial adhesin protein YdeQ b1502 ECK120003382 ydeR b1503 1587793 1588296 reverse putative fimbrial protein YdeR b1503 ECK120003383 ydeS b1504 1588309 1588839 reverse putative fimbrial protein YdeS 20345943, b1504 ECK120003384 ydeT b1505 1588853 1590001 reverse fimbrial usher domain-containing protein YdeT 20345943, b1505 ECK120003385 yneL b1506 1590334 1590536 reverse putative HTH-type transcriptional regulator YneL 11514505,28727911, b1506 ECK120000436 hipA b1507 1590854 1592176 reverse serine/threonine-protein kinase toxin HipA 23084949,23090599,23148222,24089363,26282213,26483762,28979246,30450091, b1507 ECK120000435 hipB b1508 1592176 1592442 reverse antitoxin/DNA-binding transcriptional repressor HipB 10844683,24089363, b1508 ECK120001714 yneO b4696 1592665 1598086 reverse AIDA-I family autotransporter YneO 11988218,15174130,15659678,32053772, b1509,b1510,b4696 ECK120003387 lsrK b1511 1598617 1600209 reverse autoinducer-2 kinase 20609240,20698680,21980272,22433054,22916001,23226268,23246794,25908186,28782813,30178912,30786203,32026533,33683884, b1511 ECK120003388 lsrR b1512 1600288 1601241 reverse DNA-binding transcriptional repressor LsrR b1512 ECK120003389 lsrA b1513 1601490 1603025 forward Autoinducer-2 ABC transporter ATP binding subunit [COMP|W|Inferred by computational analysis] Weak b1513 ECK120003390 lsrC b1514 1603019 1604047 forward Autoinducer-2 ABC transporter membrane subunit LsrC [COMP|W|Inferred by computational analysis] Weak b1514 ECK120003391 lsrD b1515 1604047 1605039 forward Autoinducer-2 ABC transporter membrane subunit LsrD [COMP|W|Inferred by computational analysis] Weak b1515 ECK120003392 lsrB b1516 1605051 1606073 forward Autoinducer-2 ABC transporter periplasmic binding protein 34597255,34783039, b1516 ECK120003393 lsrF b1517 1606100 1606975 forward 3-hydroxy-2,4-pentadione 5-phosphate thiolase 22384939,22916001,23246794, b1517 ECK120003394 lsrG b1518 1606999 1607289 forward (4)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase 22384939,22916001,23246794, b1518 ECK120003395 tam b1519 1607346 1608104 forward -aconitate 2-methyltransferase b1519 ECK120003396 yneE b1520 1608108 1609022 reverse PF01062 family inner membrane protein YneE 31438868, b1520 ECK120001054 uxaB b1521 1609229 1610680 reverse tagaturonate reductase 2841575,3525742,6296052,6343794,6357945, b1521 ECK120003397 dgcF b1522 1610907 1611854 reverse putative diguanylate cyclase DgcF [EXP-IMP|W|Inferred from mutant phenotype] 21181144,23202856, Weak b1522 ECK120003398 yneG b1523 1611966 1612325 reverse DUF4186 domain-containing protein YneG b1523 ECK120003399 glsB b1524 1612325 1613251 reverse glutaminase 2 b1524 ECK120003400 sad b1525 1613315 1614703 reverse succinate semialdehyde dehydrogenase (NAD(P)) Sad 20304089,22550959,26925526,29970091, b1525 ECK120003401 yneJ b1526 1614804 1615685 forward putative DNA-binding transcriptional regulator YneJ [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475,24391520, Weak b1526 ECK120003402 yneK b1527 1615763 1616878 forward protein YneK b1527 ECK120001583 ydeA b1528 1617028 1618218 forward L-arabinose exporter 22952739,31438868, b1528 ECK120001584 marC b1529 1618243 1618908 reverse inner membrane protein MarC 21179021,28645581,31186336,33292484, b1529 ECK120001399 marR b1530 1619120 1619554 forward DNA-binding transcriptional repressor MarR 8282690,8383113,8521301, b1530 ECK120001398 marA b1531 1619574 1619957 forward DNA-binding transcriptional dual regulator MarA [EXP|W|Inferred from experiment] 27105118,31251753,31438868,8383113,8491710,8522515, Weak b1531 ECK120001547 marB b1532 1619989 1620207 forward multiple antibiotic resistance protein MarB b1532 ECK120001585 eamA b1533 1620238 1621137 reverse cysteine/-acetylserine exporter EamA 10844694,12562784,12640465, b1533 ECK120001586 ydeE b1534 1621332 1622519 forward dipeptide exporter 31438868,9529885, b1534 ECK120002603 mgtS b4599 1622646 1622741 forward small protein MgtS [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IPI|W|Inferred from physical interaction],[EXP-IGI|W|Inferred from genetic interaction] 28512220,29111488, Weak b4599 ECK125286405 mgtT b4775 1622741 1622845 forward protein MgtT b4775 ECK125095180 mgrR b4698 1622817 1622914 reverse small regulatory RNA MgrR [EXP-IMP|W|Inferred from mutant phenotype] 19889087, Weak b4698 ECK120001587 dgcZ b1535 1622960 1623850 reverse diguanylate cyclase DgcZ b1535 ECK120001588 ydeI b1536 1624105 1624497 reverse BOF family protein YdeI [EXP-IMP|W|Inferred from mutant phenotype] 19919618, Weak b1536 ECK120001589 ydeJ b1537 1624773 1625291 forward PF02464 family protein YdeJ b1537 ECK120000206 dcp b1538 1625335 1627380 reverse peptidyl-dipeptidase Dcp 13271,1537811,7674945, b1538 ECK120002220 ydfG b1539 1627517 1628263 forward 3-hydroxy acid dehydrogenase YdfG 25048226,26925526, b1539 ECK120003403 rspR b1540 1628352 1629038 forward DNA-binding transcriptional repressor RspR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10734204,15556475,22972332, Strong b1540 ECK120003404 ydfZ b1541 1629215 1629418 forward putative selenoprotein YdfZ b1541 ECK120003405 ydfI b1542 1629453 1630913 reverse putative oxidoreductase YdfI b1542 ECK120003406 ydfJ b1543 1631002 1632285 reverse putative transporter YdfJ [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IDA-UNPURIFIED-PROTEIN-HH|W|Assay of unpurified protein expressed in a heterologous host] 21744086,9529885, Weak b1543 ECK125276514 ynfT b4748 1632890 1633003 forward Qin prophage; protein YnfT b4748 ECK120003407 ydfK b1544 1633072 1633305 forward Qin prophage; cold shock protein YdfK [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15556475, Weak b1544 ECK120003408 pinQ b1545 1633622 1634212 forward Qin prophage; putative recombinase PinQ b1545 ECK120003409 tfaQ b1546 1634310 1634885 reverse Qin prophage; putative tail fiber assembly protein TfaQ b1546 ECK120003410 stfQ b1547 1634885 1635847 reverse Qin prophage; putative prophage side tail fiber protein StfQ b1547 ECK120001581 nohA b1548 1635798 1636367 reverse Qin prophage; putative prophage DNA-packaging protein NohA b1548 ECK120016304 ynfO b4533 1636756 1636989 forward Qin prophage; DUF3950 domain-containing protein YnfO b4533 ECK120003411 ydfO b1549 1637047 1637457 forward Qin prophage; DUF1398 domain-containing protein YdfO 34070637, b1549 ECK120003412 gnsB b1550 1637609 1637782 reverse Qin prophage; protein GnsB [EXP-IGI|W|Inferred from genetic interaction] 11544213, Weak b1550 ECK120003413 ynfN b1551 1637954 1638109 reverse Qin prophage; protein YnfN b1551 ECK125276523 ynfR b4749 1638188 1638253 reverse Qin prophage; protein YnfR b4749 ECK125256970 ynfQ b4724 1638256 1638444 reverse Qin prophage; protein YnfQ b4724 ECK120003414 cspI b1552 1638455 1638667 reverse Qin prophage; cold shock-like protein CspI [EXP-IEP|W|Inferred from expression pattern] 10049393, Weak b1552 ECK120003415 rzpQ b1553 1639030 1639527 reverse Qin prophage; DUF2514 domain-containing protein RzpQ b1553 ECK125240988 rzoQ b4689 1639080 1639334 reverse Qin prophage; putative lipoprotein RzoQ 32053772, b4689 ECK120003416 rrrQ b1554 1639524 1640057 reverse Qin prophage; putative lysozyme b1554 ECK120003417 ydfR b1555 1640054 1640365 reverse Qin prophage; protein YdfR 24391520, b1555 ECK120003418 essQ b1556 1640370 1640585 reverse Qin prophage; putative prophage lysis protein EssQ b1556 ECK125286417 ynfU b4776 1640805 1640975 forward Qin prophage; putative zinc-binding protein YnfU b4776 ECK120002091 cspB b1557 1641339 1641554 reverse Qin prophage; cold shock-like protein CspB [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 10476034,11298285,19732898,28334975,29808326, Weak b1557 ECK120002093 cspF b1558 1641855 1642067 forward Qin prophage; cold shock-like protein CspF b1558 ECK125276533 ynfS b4750 1642122 1642211 forward Qin prophage; protein YnfS b4750 ECK120003419 ydfT b1559 1642489 1643241 reverse Qin prophage; putative antitermination protein Q b1559 ECK120003420 ydfU b1560 1643255 1644304 reverse Qin prophage; protein YdfU 24391520, b1560 ECK120001113 rem b1561 1644651 1644902 reverse Qin prophage; protein Rem b1561 ECK120001114 hokD b1562 1645119 1645274 reverse Qin prophage; toxic protein HokD [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 21255333,3019679, Strong b1562 ECK120001115 relE b1563 1645346 1645633 reverse Qin prophage; mRNA interferase toxin RelE 19161859, b1563 ECK120000827 relB b1564 1645633 1645872 reverse Qin prophage; antitoxin/DNA-binding transcriptional repressor RelB b1564 ECK120003421 ydfV b1565 1645897 1646202 forward Qin prophage; protein YdfV b1565 ECK120003422 flxA b1566 1646405 1646737 forward Qin prophage; PF14282 family protein FlxA b1566 ECK120003423 ydfW b1567 1647174 1647323 reverse Qin prophage; protein YdfW b1567 ECK120003424 ydfX b1568 1647346 1647636 reverse Qin prophage; protein YdfX b1568 ECK120000222 dicC b1569 1647620 1647850 reverse Qin prophage; putative DNA-binding transcriptional regulator DicC 31921032, b1569 ECK120000220 dicA b1570 1647934 1648341 forward DNA-binding transcriptional dual regulator DicA [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 23028867,3041373,3053647, Strong b1570 ECK120001273 ydfA b1571 1648508 1648663 forward Qin prophage; DUF1391 domain-containing protein YdfA 24391520, b1571 ECK120001274 ydfB b1572 1648665 1648793 forward Qin prophage; uncharacterized protein YdfB 24391520, b1572 ECK120001275 ydfC b1573 1648823 1649041 forward Qin prophage; uncharacterized protein YdfC b1573 ECK120002557 dicF b1574 1649382 1649434 forward Qin prophage; small regulatory RNA DicF [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 1552861,18388495,27822514,8763959, Weak b1574 ECK120000221 dicB b1575 1649609 1649797 forward Qin prophage; cell division inhibition protein DicB [EXP|W|Inferred from experiment],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 12003935,15805531,2137246,2211516,23028867,2836697,2848223,3911021,7651342, Weak b1575 ECK120001276 ydfD b1576 1649794 1649985 forward Qin prophage; lysis protein 24391520, b1576 ECK120001277 ydfE b1577 1650078 1650998 forward Qin prophage; protein YdfE 11514505, b1577 ECK120003425 insD7 b1578 1650881 1651537 forward Qin prophage; putative transposase b1578 ECK120003426 intQ b1579 1651512 1652708 forward Qin prophage; putative defective integrase b1579 ECK120026450 ynfP b4534 1652728 1652838 reverse protein YnfP b4534 ECK120003427 rspB b1580 1652896 1653915 reverse putative zinc-binding dehydrogenase RspB b1580 ECK120003428 rspA b1581 1653927 1655141 reverse mandelate racemase/muconate lactonizing enzyme family protein RspA [AS-NAS|W|Non-traceable author statement],[EXP-IGI|W|Inferred from genetic interaction] 15581566,7545940, Weak b1581 ECK120003429 ynfA b1582 1655347 1655673 reverse putative transporter YnfA 31438868, b1582 ECK120003430 ynfB b1583 1655808 1656149 forward DUF1283 domain-containing protein YnfB 24391520, b1583 ECK120003431 speG b1584 1656184 1656744 forward spermidine -acetyltransferase b1584 ECK120003432 ynfC b1585 1656747 1657457 reverse PF06788 family lipoprotein YnfC 15126489,15174130,15215418,32053772, b1585 ECK120003433 ynfD b1586 1657565 1657870 forward DUF1161 domain-containing protein YnfD 24391520, b1586 ECK120003434 ynfE b1587 1658069 1660495 forward putative selenate reductase YnfE 14522592, b1587 ECK120003435 ynfF b1588 1660556 1662979 forward putative selenate reductase YnfF b1588 ECK120003436 ynfG b1589 1662990 1663607 forward putative oxidoreductase YnfG b1589 ECK120003437 ynfH b1590 1663609 1664463 forward putative menaquinol dehydrogenase 14757221, b1590 ECK120003438 dmsD b1591 1664506 1665120 forward redox enzyme maturation protein DmsD [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 14766221, Weak b1591 ECK120003439 clcB b1592 1665315 1666571 forward putative chloride:H antiporter ClcB 11917096, b1592 ECK120003440 bidA b1593 1666524 1667219 reverse dethiobiotin synthetase BidA b1593 ECK120003441 mlc b1594 1667344 1668564 reverse DNA-binding transcriptional repressor Mlc [EXP-IDA-BINDING-OF-CELLULAR-EXTRACTS|W|Binding of cellular extracts],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 10464268,10469172,9484892,9484893,9767573, Weak b1594 ECK120003442 ynfL b1595 1668699 1669592 reverse putative DNA-binding transcriptional regulator YnfL [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b1595 ECK120003443 ynfM b1596 1669699 1670952 forward putative transporter YnfM 31438868, b1596 ECK125135295 Phantom Gene 1670949 1671136 reverse ECK120003444 asr b1597 1671376 1671684 forward acid shock protein [EXP-IMP|W|Inferred from mutant phenotype] 12670971,22460638, Weak b1597 ECK120030077 ydgU b4601 1671777 1671860 forward uncharacterized protein YdgU b4601 ECK120003445 ydgD b1598 1671960 1672781 forward putative serine protease YdgD b1598 ECK120003446 mdtI b1599 1672820 1673149 reverse multidrug/spermidine efflux pump membrane subunit MdtI 31438868, b1599 ECK120003447 mdtJ b1600 1673136 1673501 reverse multidrug/spermidine efflux pump membrane subunit MdtJ 11914367,12618449,31438868,33685971, b1600 ECK125286392 mdtU b4777 1673608 1673709 reverse protein MdtU 33460557, b4777 ECK120003448 tqsA b1601 1673913 1674947 forward autoinducer 2 exporter 14727089,31438868, b1601 ECK120000736 pntB b1602 1674972 1676360 reverse pyridine nucleotide transhydrogenase subunit β 10481061,11027139, b1602 ECK120000735 pntA b1603 1676371 1677903 reverse pyridine nucleotide transhydrogenase subunit α 16083909, b1603 ECK120003449 ydgH b1604 1678427 1679371 forward DUF1471 domain-containing protein YdgH b1604 ECK120003450 ydgI b1605 1679557 1680939 forward putative arginine:ornithine antiporter [AS-NAS|W|Non-traceable author statement] 16385049,31438868, Weak b1605 ECK120003451 folM b1606 1680976 1681698 forward dihydromonapterin reductase b1606 ECK120003452 ydgC b1607 1681695 1682030 reverse GlpM family protein b1607 ECK120003453 rstA b1608 1682159 1682878 forward DNA-binding transcriptional regulator RstA b1608 ECK120001211 rstB b1609 1682882 1684183 forward sensory histidine kinase RstB b1609 ECK120001027 tus b1610 1684259 1685188 forward DNA replication terminus site-binding protein [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 8051142, Weak b1610 ECK120000351 fumC b1611 1685185 1686588 reverse fumarase C 19383690,22752906,3005475,3541901, b1611 ECK120000349 fumA b1612 1686731 1688377 reverse fumarase A 19383690,5330664, b1612 ECK120000559 manA b1613 1688576 1689751 forward mannose-6-phosphate isomerase b1613 ECK120003454 ydgA b1614 1689852 1691360 forward DUF945 domain-containing protein YdgA b1614 ECK120003455 uidC b1615 1691586 1692851 reverse outer membrane porin family protein UidC b1615 ECK120001601 uidB b1616 1692890 1694263 reverse glucuronide:H symporter b1616 ECK120001044 uidA b1617 1694260 1696071 reverse β-glucuronidase 21296758,21348473,21859154,21952673,22328575,22535688,22655749,24611780,24780296,26225370,4215595,776933,776934, b1617 ECK120003456 uidR b1618 1696462 1697052 reverse DNA-binding transcriptional repressor UidR [EXP-IEP|W|Inferred from expression pattern],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 2823062,3079718,3934044,6276362,776933,776934, Weak b1618 ECK120000418 hdhA b1619 1697273 1698040 reverse 7-α-hydroxysteroid dehydrogenase 15299750,17224607,34171491, b1619 ECK120000550 malI b1620 1698152 1699180 reverse DNA-binding transcriptional repressor MalI [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[COMP|W|Inferred by computational analysis] 1856179,2670898, Weak b1620 ECK120000556 malX b1621 1699355 1700947 forward PTS enzyme IIBC component MalX 8246840, b1621 ECK120000557 malY b1622 1700957 1702129 forward negative regulator of MalT activity/cystathionine β-lyase b1622 ECK120000027 add b1623 1702233 1703234 forward adenosine deaminase 1998686,765747, b1623 ECK120003457 ydgJ b1624 1703268 1704308 reverse putative oxidoreductase YdgJ b1624 ECK120002650 blr b4409 1704551 1704676 forward β-lactam resistance protein [EXP-IMP|W|Inferred from mutant phenotype] 10931331,19734312, Weak b4409 ECK120003458 cnu b1625 1704949 1705164 forward H-NS- and StpA-binding protein [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[EXP-IMP|W|Inferred from mutant phenotype] 15458420,21602341,22096603,23661089, Strong b1625 ECK120003459 ydgK b1626 1705250 1705690 forward DUF2569 domain-containing inner membrane protein YdgK b1626 ECK120003460 rsxA b1627 1705767 1706348 forward SoxR [2Fe-2S] reducing system protein RsxA [COMP-HINF|W|Inferred by a human based on computational evidence] 12773378, Weak b1627 ECK120003461 rsxB b1628 1706348 1706926 forward SoxR [2Fe-2S] reducing system protein RsxB [COMP-HINF|W|Inferred by a human based on computational evidence],[EXP-IMP|W|Inferred from mutant phenotype] 12773378, Weak b1628 ECK120003462 rsxC b1629 1706919 1709141 forward SoxR [2Fe-2S] reducing system protein RsxC [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[COMP-HINF|W|Inferred by a human based on computational evidence] 12773378, Strong b1629 ECK120003463 rsxD b1630 1709142 1710200 forward SoxR [2Fe-2S] reducing system protein RsxD [COMP-HINF|W|Inferred by a human based on computational evidence] 11574054,12773378, Weak b1630 ECK120003464 rsxG b1631 1710204 1710824 forward SoxR [2Fe-2S] reducing system protein RsxG [COMP-HINF|W|Inferred by a human based on computational evidence] 12773378,21072677, Weak b1631 ECK120003465 rsxE b1632 1710828 1711523 forward SoxR [2Fe-2S] reducing system protein RsxE [COMP-HINF|W|Inferred by a human based on computational evidence],[EXP-IMP|W|Inferred from mutant phenotype] 12773378, Weak b1632 ECK120000655 nth b1633 1711523 1712158 forward endonuclease III 10497792,10637328,10677682,10956660,11328881,11328882,11341839,11951664,12582238,12717778,12832627,14726482,15606310,15944451,16096281,16547199,17599416,17870674,21651304,22308447,2457010,24738733,2475855,2548577,25869130,27174933,30617079,3886628,7791217,7806489,8789150,9171430,9461450,9601036,9686872, b1633 ECK120003466 dtpA b1634 1712769 1714271 forward dipeptide/tripeptide:H symporter DtpA 10537211,11513805,21558271,2227366,27916534,28214542,3301822,7007121, b1634 ECK120003467 gstA b1635 1714377 1714982 forward glutathione -transferase GstA b1635 ECK120003468 pdxY b1636 1715026 1715889 reverse pyridoxal kinase 2 b1636 ECK120001032 tyrS b1637 1715948 1717222 reverse tyrosine—tRNA ligase 11946953,17889423,23891164,24882676,26676967,27487455,27639881,27939931, b1637 ECK120001443 pdxH b1638 1717351 1718007 reverse pyridoxine/pyridoxamine 5'-phosphate oxidase b1638 ECK120001444 mliC b1639 1718066 1718395 reverse inhibitor of c-type lysozyme, putative lipoprotein [EXP-IDA-PART-PURIFIED-PROTEIN|W|Assay of partially-purified protein ] 18369469,32053772, Weak b1639 ECK120003469 anmK b1640 1718493 1719602 reverse anhydro--acetylmuramic acid kinase 23082955, b1640 ECK120003470 slyB b1641 1719876 1720343 forward outer membrane lipoprotein SlyB [EXP-IDA|W|Inferred from direct assay] 21210718,32053772, Weak b1641 ECK120003471 slyA b1642 1720390 1720824 reverse DNA-binding transcriptional dual regulator SlyA b1642 ECK120003472 ydhI b1643 1721025 1721261 forward DUF1656 domain-containing protein YdhI b1643 ECK120003473 ydhJ b1644 1721264 1722121 forward putative membrane fusion protein YdhJ 31438868, b1644 ECK120003474 ydhK b1645 1722121 1724133 forward putative transporter YdhK 31438868, b1645 ECK120003475 sodC b1646 1724134 1724655 reverse superoxide dismutase (Cu-Zn) b1646 ECK120003476 ydhF b1647 1724736 1725632 reverse putative oxidoreductase YdhF b1647 ECK120003477 ydhL b1648 1725681 1725920 reverse DUF1289 domain-containing protein YdhL 34070637, b1648 ECK120003478 nemR b1649 1726023 1726622 forward DNA-binding transcriptional repressor NemR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 15556475,18567656, Weak b1649 ECK120003479 nemA b1650 1726659 1727756 forward -ethylmaleimide reductase b1650 ECK120003480 gloA b1651 1727837 1728244 forward lactoylglutathione lyase 24670003,25670698,32141296, b1651 ECK120001501 rnt b1652 1728347 1728994 forward ribonuclease T b1652 ECK120001502 lhr b1653 1729087 1733703 forward ATP-dependent helicase Lhr b1653 ECK120002074 grxD b1654 1733754 1734101 reverse glutaredoxin 4 23543739, b1654 ECK120003481 mepH b1655 1734435 1735250 forward peptidoglycan endopeptidase/peptidoglycan L,D-carboxypeptidase MepH b1655 ECK120000943 sodB b1656 1735378 1735959 forward superoxide dismutase (Fe) 11197024,11736645,11766965,11800609,11811537,11929218,12485776,12837107,15253658,15260508,1588912,17044650,17299591,17827717,18338221,19182373,19223646,19679357,20305033,2071033,22094925,2241146,2643390,3298208,3305077,4590170,6087358,7574689,7872803,8382113,8392020,9367535,9719674,9933617, b1656 ECK120003482 ydhP b1657 1736121 1737290 reverse putative transporter YdhP 31438868, b1657 ECK120030078 cydH b4602 1737456 1737545 reverse cytochrome -I accessory subunit CydH b4602 ECK120000791 purR b1658 1737844 1738869 forward DNA-binding transcriptional repressor PurR 2211510,2404765,3058704, b1658 ECK120002041 punR b1659 1738866 1739798 reverse DNA-binding transcriptional activator PunR [COMP-HINF|W|Inferred by a human based on computational evidence],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 11566977,15556475,34413462,9022701, Weak b1659 ECK120002042 punC b1660 1739911 1741122 forward purine nucleoside transporter PunC [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 31438868,34413462, Weak b1660 ECK120001485 cfa b1661 1741413 1742561 forward cyclopropane fatty acyl phospholipid synthase 18562182,24726609,29450618,30252972, b1661 ECK120001372 ribC b1662 1742601 1743242 reverse riboflavin synthase b1662 ECK120002262 mdtK b1663 1743457 1744830 forward multidrug efflux pump MdtK b1663 ECK120003483 ydhQ b1664 1744871 1746127 reverse putative adhesin-related protein YdhQ b1664 ECK120002553 valV b1665 1746435 1746511 forward tRNA-Val(GAC) [AS-TAS|W|Traceable author statement] 7033244, Weak b1665 ECK120002554 valW b1666 1746516 1746592 forward tRNA-Val(GAC) [AS-TAS|W|Traceable author statement] 7033244, Weak b1666 ECK120003484 ydhR b1667 1746700 1747005 forward putative monooxygenase YdhR b1667 ECK120003485 ydhS b1668 1747131 1748735 forward FAD/NAD(P) binding domain-containing protein YdhS b1668 ECK120003486 ydhT b1669 1748747 1749559 reverse uncharacterized protein YdhT 28218056, b1669 ECK120003487 ydhU b1670 1749563 1750348 reverse putative cytochrome YdhU 28218056, b1670 ECK120003488 ydhX b1671 1750345 1751013 reverse putative 4Fe-4S ferredoxin-like protein YdhX 28218056, b1671 ECK120003489 ydhW b1672 1751077 1751724 reverse uncharacterized protein YdhW 28218056, b1672 ECK120003490 ydhV b1673 1751728 1753830 reverse putative oxidoreductase YdhV 28218056, b1673 ECK120003491 ydhY b1674 1753851 1754477 reverse putative 4Fe-4S ferredoxin-like protein YdhY 28218056, b1674 ECK120003492 fumD b1675 1754932 1755141 reverse fumarase D b1675 ECK125303722 ynhH b4817 1755496 1755690 forward protein YnhH b4817 ECK120000795 pykF b1676 1755698 1757110 forward pyruvate kinase 1 b1676 ECK120000537 lpp b1677 1757421 1757657 forward murein lipoprotein b1677 ECK120003493 ldtE b1678 1757721 1758725 reverse L,D-transpeptidase LdtE 31743648, b1678 ECK120003494 sufE b1679 1758874 1759290 reverse sulfur carrier protein SufE [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 12941942,15930006,23472115,23913692,29589903,30571100, Weak b1679 ECK120003495 sufS b1680 1759303 1760523 reverse L-cysteine desulfurase 11997471,15496591,15688436,15862443,19919618,20936830,23913692,26171726, b1680 ECK120003496 sufD b1681 1760520 1761791 reverse Fe-S cluster scaffold complex subunit SufD b1681 ECK120003497 sufC b1682 1761766 1762512 reverse Fe-S cluster scaffold complex subunit SufC 23018275,31438868, b1682 ECK120003498 sufB b1683 1762522 1764009 reverse Fe-S cluster scaffold complex subunit SufB b1683 ECK120001346 sufA b1684 1764018 1764386 reverse iron-sulfur cluster insertion protein SufA b1684 ECK120002588 rydB b4430 1764713 1764780 reverse small regulatory RNA RydB [EXP-IMP|W|Inferred from mutant phenotype] 11445539,12069726,21546360, Weak b4430 ECK120003499 ydiH b1685 1764934 1765122 reverse uncharacterized protein YdiH b1685 ECK120003500 menI b1686 1765222 1765632 reverse 1,4-dihydroxy-2-naphthoyl-CoA hydrolase b1686 ECK120003501 ydiJ b1687 1765629 1768685 reverse putative FAD-linked oxidoreductase YdiJ 23228329, b1687 ECK120003502 ydiK b1688 1769074 1770186 forward putative transporter YdiK 31438878, b1688 ECK120002576 rprA b4431 1770372 1770477 forward small regulatory RNA RprA [EXP-IDA|W|Inferred from direct assay],[EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 11251852,11448770,12410838,17264113,18826256,20455949,26264774,28479746,29294085,29905843,30287822,30562360,30802490,31186337,31552789, Weak b4431 ECK120003503 ydiL b1689 1770615 1770971 forward DUF1870 domain-containing protein YdiL b1689 ECK120003504 ydiM b1690 1771071 1772285 forward putative exporter YdiM 11566977,26563610,31438868, b1690 ECK120003505 ydiN b1691 1772512 1773777 forward putative transporter YdiN 31438878, b1691 ECK120001212 ydiB b1692 1773789 1774655 forward quinate/shikimate dehydrogenase 18243023,22728194,23631118,24905044,26442259,32268068, b1692 ECK120000072 aroD b1693 1774686 1775444 forward 3-dehydroquinate dehydratase b1693 ECK120002287 ydiF b1694 1775587 1777182 forward putative acetate-CoA transferase YdiF b1694 ECK120003506 ydiO b1695 1777196 1778347 forward putative acyl-CoA dehydrogenase YdiO [COMP-HINF|W|Inferred by a human based on computational evidence] 12535077,22105550,29369593, Weak b1695 ECK120003507 ydiP b1696 1778390 1779301 reverse putative DNA-binding transcriptional regulator YdiP [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475,24391520, Weak b1696 ECK120003508 ydiQ b1697 1779617 1780381 forward putative electron transfer flavoprotein subunit YdiQ [COMP-HINF|W|Inferred by a human based on computational evidence] 12535077, Weak b1697 ECK120003509 ydiR b1698 1780401 1781339 forward putative electron transfer flavoprotein subunit YdiR [COMP-HINF|W|Inferred by a human based on computational evidence] 12535077, Weak b1698 ECK120003510 ydiS b1699 1781395 1782684 forward putative electron transfer flavoprotein-quinone oxidoreductase YdiS [COMP-HINF|W|Inferred by a human based on computational evidence] 12535077,24391520,29915570, Weak b1699 ECK120003511 ydiT b1700 1782681 1782974 forward ferredoxin-like protein YdiT [COMP-HINF|W|Inferred by a human based on computational evidence] 12535077, Weak b1700 ECK120002225 fadK b1701 1782977 1784677 forward short chain acyl-CoA synthetase b1701 ECK120000750 ppsA b1702 1784734 1787112 reverse phosphoenolpyruvate synthetase b1702 ECK120001116 ppsR b1703 1787445 1788278 forward phosphoenolpyruvate synthetase regulatory protein b1703 ECK120000076 aroH b1704 1788435 1789481 forward 3-deoxy-7-phosphoheptulonate synthase, Trp-sensitive 2903857, b1704 ECK120002254 ydiE b1705 1789613 1789804 forward PF10636 family protein YdiE b1705 ECK120003512 selO b1706 1789808 1791244 reverse protein adenylyltransferase SelO b1706 ECK120003513 rflP b1707 1791307 1792020 reverse anti-FlhDC factor RflP [EXP|W|Inferred from experiment] 22461489, Weak b1707 ECK120001117 nlpC b1708 1792267 1792731 reverse NlpC/P60 family lipoprotein NlpC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 12620121,12876315,15174130,32053772,9573210, Weak b1708 ECK120000124 btuD b1709 1792809 1793558 reverse vitamin B ABC transporter ATP binding subunit b1709 ECK120000125 btuE b1710 1793558 1794109 reverse thioredoxin/glutathione peroxidase BtuE 1830209,26960359, b1710 ECK120000123 btuC b1711 1794172 1795152 reverse vitamin B ABC transporter membrane subunit 23959879,33554862, b1711 ECK120000433 ihfA b1712 1795253 1795552 reverse integration host factor subunit α 7651128,7715442, b1712 ECK120000702 pheT b1713 1795557 1797944 reverse phenylalanine—tRNA ligase subunit β 4942764,783122, b1713 ECK120000701 pheS b1714 1797959 1798942 reverse phenylalanine—tRNA ligase subunit α 24811065,25652032,29660847,783122, b1714 ECK120001246 pheM b1715 1799226 1799270 reverse operon leader peptide [EXP-IMP|W|Inferred from mutant phenotype] 3126825,3158742,3162032,34070637,6096210, Weak b1715 ECK120000872 rplT b1716 1799393 1799749 reverse 50S ribosomal subunit protein L20 1107798,11470155,1453449,16739990,1706660,20097853,2185470,23396277,2419169,2664451,2838394,3158742,3298242,3302616,3512304,3542048,378264,381019,6160475,6163479,6201363,6317865,6353409,68433,7038683,786630,813873,9371771, b1716 ECK120001209 rpmI b1717 1799802 1799999 reverse 50S ribosomal subunit protein L35 1453449,8722036,8955899, b1717 ECK120000499 infC b1718 1800096 1800638 reverse translation initiation factor IF-3 [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 25308340,26324939,4922687,9352920, Weak b1718 ECK120000990 thrS b1719 1800642 1802570 reverse threonine—tRNA ligase 1098926,11453682,12875846,15380559,17384228,18946032,22607403,24339747,2457500,2512999,2838394,29320932,30239743,3072248,318645,318654,32291821,341085,348470,3531168,368026,372755,4368395,4568008,6154481,6215395,6254853,6290444,6353409,6368838,6405814,6749810,7012115,7042343,7050631,7544283, b1719 ECK120003514 arpB b4494 1803094 1804993 forward putative ankyrin repeat protein B, N-terminal fragment b1720,b1721,b4494 ECK120016305 yniD b4535 1805165 1805272 forward uncharacterized protein YniD b4535 ECK120003516 ydiY b1722 1805325 1806083 reverse acid-inducible putative outer membrane protein YdiY [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 12192075,24391520, Weak b1722 ECK120000692 pfkB b1723 1806370 1807299 forward 6-phosphofructokinase 2 b1723 ECK120003517 ydiZ b1724 1807400 1807690 forward putative endoribonuclease YdiZ 24391520, b1724 ECK120003518 yniA b1725 1807796 1808656 forward putative kinase YniA b1725 ECK120003519 yniB b1726 1808697 1809233 reverse uncharacterized protein YniB b1726 ECK120003520 hxpB b1727 1809380 1810048 forward hexitol phosphatase B b1727 ECK120003521 ydjM b1728 1810211 1810801 forward inner membrane protein YdjM b1728 ECK120003522 tcyP b1729 1810934 1812325 forward cystine/sulfocysteine:cation symporter 15262924,15659685,31208335,32518189, b1729 ECK120003523 ydjO b1730 1812329 1813132 reverse protein YdjO b1730 ECK120003524 cedA b1731 1813421 1813663 reverse cell division modulator [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 15865419,9427399, Weak b1731 ECK120000502 katE b1732 1813867 1816128 forward catalase HPII 10802173,11440837,11763776,12589799,12916153,1324193,1385595,14980071,15915708,16183297,17400245,2254248,2977357,6094482, b1732 ECK120002087 chbG b1733 1816386 1817135 reverse chitooligosaccharide monodeacetylase ChbG b1733 ECK120000140 chbF b1734 1817148 1818500 reverse monoacetylchitobiose-6-phosphate hydrolase 15066032,2179047,8121401, b1734 ECK120000139 chbR b1735 1818605 1819447 reverse ChbR b1735 ECK120000138 chbA b1736 1819455 1819805 reverse -diacetylchitobiose-specific PTS enzyme IIA component b1736 ECK120000137 chbC b1737 1819856 1821214 reverse -diacetylchitobiose-specific PTS enzyme IIC component b1737 ECK120000136 chbB b1738 1821299 1821619 reverse -diacetylchitobiose-specific PTS enzyme IIB component b1738 ECK120000040 osmE b1739 1821918 1822256 reverse osmotically-inducible lipoprotein OsmE 32053772, b1739 ECK120000656 nadE b1740 1822458 1823285 forward NH synthetase 21742902,28629697,7565114, b1740 ECK120003525 cho b1741 1823515 1824402 forward excinuclease Cho [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 11818552, Weak b1741 ECK120003526 ves b1742 1824362 1824937 reverse HutD family protein Ves [COMP-HINF|W|Inferred by a human based on computational evidence] 11873911,25611733, Weak b1742 ECK120003527 spy b1743 1825140 1825625 reverse ATP-independent periplasmic chaperone b1743 ECK120003528 astE b1744 1825955 1826923 reverse succinylglutamate desuccinylase b1744 ECK120003529 astB b1745 1826916 1828259 reverse -succinylarginine dihydrolase b1745 ECK120003530 astD b1746 1828256 1829734 reverse aldehyde dehydrogenase b1746 ECK120003531 astA b1747 1829731 1830765 reverse arginine -succinyltransferase b1747 ECK120003532 astC b1748 1830762 1831982 reverse succinylornithine transaminase b1748 ECK120001062 xthA b1749 1832428 1833234 forward exodeoxyribonuclease III 10780446,1091930,14114850,14114851,1508730,15209514,16524897,18034795,18282002,200266,20667510,23898172,2429316,2430946,2541439,2663068,27150717,3001698,3049539,30530516,326780,342234,4341749,4570597,6246343,6260569,6282808,6355066,6752885,7520446,773929,780339,781281,7885481,794874,8092679,8421304,8470795,8841565,8948651,9188454, b1749 ECK120003533 ydjX b1750 1833401 1834111 forward DedA family protein YdjX b1750 ECK120003534 ydjY b1751 1834116 1834793 forward 4Fe-4S ferredoxin-type domain-containing protein YdjY b1751 ECK120003535 ydjZ b1752 1834808 1835515 forward DedA family protein YdjZ 11574054,24391520, b1752 ECK120003536 ynjA b1753 1835515 1836063 forward AhpD-like domain-containing protein YnjA b1753 ECK120003537 ynjB b1754 1836073 1837239 forward putative ABC transporter periplasmic binding protein YnjB 31438868, b1754 ECK120003538 ynjC b1755 1837212 1838747 forward putative ABC transporter membrane subunit YnjC 18180259,31438868, b1755 ECK120003539 ynjD b1756 1838747 1839400 forward putative ABC transporter ATP-binding protein YnjD 31438868, b1756 ECK120003540 ynjE b1757 1839467 1840774 forward molybdopterin synthase sulfurtransferase b1757 ECK120003541 ynjF b1758 1840783 1841403 reverse CDP-alcohol phosphatidyltransferase domain-containing protein YnjF 28815570, b1758 ECK120003542 nudG b1759 1841490 1841897 forward 5-hydroxy-CTP diphosphatase 18575227,29511080, b1759 ECK120003543 ynjH b1760 1841863 1842135 reverse DUF1496 domain-containing protein YnjH b1760 ECK120000365 gdhA b1761 1842371 1843714 forward glutamate dehydrogenase b1761 ECK120003544 ynjI b1762 1843831 1844871 reverse DUF1266 domain-containing protein YnjI b1762 ECK120001003 topB b1763 1844999 1846960 reverse DNA topoisomerase III 12844871,14517231,18554330,22373098,25197978,26444226,26947024,29177738,33740684,366396,6353164,7657674,7798272,7851754,8850348,9164483, b1763 ECK120000932 selD b1764 1846965 1848008 reverse selenide, water dikinase b1764 ECK120001118 ydjA b1765 1848125 1848676 reverse putative oxidoreductase YdjA 18084095, b1765 ECK120000957 sppA b1766 1848837 1850693 forward protease IV, a signal peptide peptidase b1766 ECK120000041 ansA b1767 1850860 1851876 forward L-asparaginase 1 b1767 ECK120001119 pncA b1768 1851887 1852528 forward nicotinamidase 13717628,2670682,3294796,4245200,780339,8726014, b1768 ECK120002237 ydjE b1769 1852621 1853979 reverse putative transporter YdjE 31438868, b1769 ECK120003545 ydjF b1770 1854096 1854854 reverse putative DNA-binding transcriptional regulator YdjF [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15556475, Weak b1770 ECK120003546 ydjG b1771 1854991 1855971 reverse NADH-dependent methylglyoxal reductase b1771 ECK120003547 ydjH b1772 1855981 1856928 reverse L--L-galacto-octuluronate kinase b1772 ECK120003548 ydjI b1773 1856933 1857769 reverse L--L-galacto-octuluronate-1-phosphate aldolase b1773 ECK120003549 ydjJ b1774 1857790 1858833 reverse putative zinc-binding dehydrogenase YdjJ 24391520, b1774 ECK120003550 ydjK b1775 1858850 1860229 reverse putative transporter YdjK 31438868, b1775 ECK120003551 ydjL b1776 1860256 1861332 reverse putative zinc-binding dehydrogenase YdjL b1776 ECK120003552 yeaC b1777 1861702 1861974 reverse DUF1315 domain-containing protein YeaC b1777 ECK120002257 msrB b1778 1862016 1862429 reverse methionine sulfoxide reductase B 10360685,11677230,16735467,7017726, b1778 ECK120000360 gapA b1779 1862771 1863766 forward glyceraldehyde-3-phosphate dehydrogenase A 9260967,9696782, b1779 ECK120003553 yeaD b1780 1863850 1864734 forward putative aldose 1-epimerase YeaD b1780 ECK120003554 yeaE b1781 1864782 1865636 reverse methylglyoxal reductase YeaE 23990306, b1781 ECK120003555 mipA b1782 1865726 1866472 reverse MltA-interacting protein [EXP-IPI|W|Inferred from physical interaction] 10037771,12949085,16760308,17190827,17513478,19068836,25940639, Weak b1782 ECK120003556 yeaG b1783 1866908 1868842 forward protein kinase YeaG [EXP-IMP|W|Inferred from mutant phenotype] 19004873,26621053, Weak b1783 ECK120003557 yeaH b1784 1868955 1870238 forward DUF444 domain-containing protein YeaH 19004873, b1784 ECK120003558 cdgI b1785 1870385 1871860 forward putative c-di-GMP binding protein CdgI b1785 ECK120003559 dgcJ b1786 1872041 1873531 forward diguanylate cyclase DgcJ 21181144,29196655,34309400, b1786 ECK120003560 yeaK b1787 1873574 1874077 forward mischarged aminoacyl-tRNA deacylase [EXP-IDA|W|Inferred from direct assay] 23564458,25918376, Weak b1787 ECK120003561 yoaI b1788 1874078 1874182 reverse protein YoaI 34809459, b1788 ECK120003562 yeaL b1789 1874352 1874798 forward DUF441 domain-containing inner membrane protein YeaL b1789 ECK120003563 nimR b1790 1874755 1875576 reverse DNA-binding transcriptional repressor NimR [EXP-IEP|W|Inferred from expression pattern],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 15556475,25790494, Strong b1790 ECK120003564 nimT b1791 1875673 1876854 forward 2-nitroimidazole exporter 31438868, b1791 ECK120003565 yeaO b1792 1876909 1877256 forward DUF488 domain-containing protein YeaO b1792 ECK120003566 yoaF b1793 1877278 1877532 reverse DUF333 domain-containing lipoprotein YoaF b1793 ECK120003567 dgcP b1794 1877715 1878740 forward diguanylate cyclase DgcP b1794 ECK120048861 yoaK b4676 1878773 1878871 forward uncharacterized membrane protein YoaK b4676 ECK120048860 yoaJ b4675 1878874 1878948 forward uncharacterized protein YoaJ b4675 ECK120003568 yeaQ b1795 1879007 1879255 reverse PF04226 family protein YeaQ b1795 ECK120003569 yoaG b1796 1879403 1879585 reverse DUF1869 domain-containing protein YoaG b1796 ECK120003570 yeaR b1797 1879589 1879948 reverse DUF1971 domain-containing protein YeaR b1797 ECK120003571 leuE b1798 1880121 1880759 reverse leucine exporter b1798 ECK120003572 dmlR b1799 1880886 1881809 reverse DNA-binding transcriptional regulator DmlR [EXP-IEP|W|Inferred from expression pattern],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 15556475,17088549,20233924, Weak b1799 ECK120003573 dmlA b1800 1881912 1882997 forward D-malate/3-isopropylmalate dehydrogenase (decarboxylating) b1800 ECK120003574 yeaV b1801 1883188 1884633 forward putative transporter YeaV 16397293,31438868, b1801 ECK120003575 yeaW b1802 1884665 1885789 forward carnitine monooxygenase subunit YeaW b1802 ECK120003576 yeaX b1803 1885845 1886810 forward carnitine monooxygenase subunit YeaX b1803 ECK120000849 rnd b1804 1886864 1887991 reverse RNase D 3041371,6283310, b1804 ECK120002644 sroD 1888017 1888102 reverse ECK120001484 fadD b1805 1888061 1889746 reverse long-chain-fatty-acid—CoA ligase 27718375,4887396,4928881, b1805 ECK120003577 yeaY b1806 1889951 1890532 reverse Slp family lipoprotein YeaY 32053772, b1806 ECK120003578 tsaB b1807 1890572 1891267 reverse N-L-threonylcarbamoyladenine synthase, TsaB subunit 20701780,24061173, b1807 ECK120003579 yoaA b1808 1891325 1893235 reverse putative ATP-dependent 5' to 3' DNA helicase [COMP-HINF-ISM|W|Inferred from Sequence Model],[EXP-IMP|W|Inferred from mutant phenotype] 26544712,27150717, Weak b1808 ECK120003580 yoaB b1809 1893367 1893711 forward RutC family protein YoaB [EXP-IMP|W|Inferred from mutant phenotype] 14731270, Weak b1809 ECK120003581 yoaC b1810 1894133 1894432 forward DUF1889 domain-containing protein YoaC b1810 ECK120003582 yoaH b1811 1894552 1894731 reverse UFP0181 family protein YoaH b1811 ECK120000676 pabB b1812 1894805 1896166 forward aminodeoxychorismate synthase subunit 1 11975992,28338893,3291877,7896119, b1812 ECK120002358 nudL b1813 1896170 1896748 forward putative NUDIX hydrolase with low 3-phosphohydroxypyruvate phosphatase activity b1813 ECK120000919 sdaA b1814 1896932 1898296 forward L-serine deaminase I b1814 ECK120003583 pdeD b1815 1898427 1900025 forward putative c-di-GMP phosphodiesterase PdeD 29018125, b1815 ECK120003584 yoaE b1816 1900029 1901585 reverse TerC family inner membrane protein YoaE 31438868, b1816 ECK125276512 yoaL b4751 1901573 1901731 reverse protein YoaL b4751 ECK120000560 manX b1817 1902048 1903019 forward mannose-specific PTS enzyme IIAB component 8676384,9030753, b1817 ECK120000561 manY b1818 1903082 1903882 forward mannose-specific PTS enzyme IIC component 7811395,7890636, b1818 ECK120000562 manZ b1819 1903895 1904746 forward mannose-specific PTS enzyme IID component 7811395, b1819 ECK120003585 yobD b1820 1904801 1905259 forward DUF986 domain-containing inner membrane protein YobD b1820 ECK120003586 mntP b1821 1905688 1906254 forward Mn exporter 21239586,24794564,25794619,28928443, b1821 ECK120002094 rlmA b1822 1906251 1907060 reverse 23S rRNA mG745 methyltransferase b1822 ECK120002092 cspC b1823 1907226 1907435 reverse transcription antiterminator and regulator of mRNA stability CspC [EXP-IDA|W|Inferred from direct assay],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 10884409,15556475,19624711,27091548,32753505,32931907, Weak b1823 ECK120003587 yobF b1824 1907448 1907591 reverse DUF2527 domain-containing protein YobF [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 19734312,19734316, Weak b1824 ECK120003588 yebO b1825 1908261 1908548 reverse uncharacterized protein YebO 24391520, b1825 ECK120003589 mgrB b1826 1908623 1908766 reverse PhoQ kinase inhibitor [EXP-IMP|W|Inferred from mutant phenotype] 10464230,17909183,19734312,20041203,22267510,29111488,29802191,33395414,33865677,34591012, Weak b1826 ECK120016306 yobH b4536 1908925 1909164 forward uncharacterized protein YobH b4536 ECK120003590 kdgR b1827 1909308 1910099 reverse DNA-binding transcriptional repressor KdgR [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 11566977,15659677,4359651, Weak b1827 ECK120003591 yebQ b1828 1910276 1911649 forward putative transporter YebQ 31438868, b1828 ECK120000455 htpX b1829 1911695 1912576 reverse protease HtpX [EXP-IEP|W|Inferred from expression pattern],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 16076848,1826904,24769134, Strong b1829 ECK120000751 prc b1830 1912768 1914816 reverse tail-specific protease 14760686,15047720,25426869,2880842,2896198, b1830 ECK120002409 proQ b1831 1914836 1915534 reverse RNA chaperone ProQ [EXP-IDA|W|Inferred from direct assay],[EXP-IGI|W|Inferred from genetic interaction] 21381725,2536686,28317076,28334975,6355059, Weak b1831 ECK120003592 msrC b1832 1915631 1916128 reverse free methionine-()-sulfoxide reductase b1832 ECK120003593 letA b1833 1916258 1917541 forward intermembrane transport protein LetA 15044727,15919996,26774489,28388411, b1833 ECK120003594 letB b1834 1917510 1920143 forward lipophilic envelope spanning tunnel b1834 ECK120003595 rsmF b1835 1920223 1921662 forward 16S rRNA mC1407 methyltransferase b1835 ECK120003596 yebV b1836 1921780 1922016 forward DUF1480 domain-containing protein YebV 32828304, b1836 ECK120003597 yebW b1837 1922121 1922312 forward DUF1482 domain-containing protein YebW 24391520, b1837 ECK120003598 pphA b1838 1922313 1922969 reverse phosphoprotein phosphatase 1 16079345,19948861, b1838 ECK120002577 ryeA b4432 1923066 1923337 forward small antisense RNA RyeA 11448770,12069726,12762038,28314872,31270363, b4432 ECK120002594 sdsR b4433 1923104 1923207 reverse small regulatory RNA SdsR [EXP-IMP|W|Inferred from mutant phenotype] 11553332,18467773,25724987,26469694,32087965, Weak b4433 ECK120003599 yebY b1839 1923365 1923706 reverse DUF2511 domain-containing protein YebY [EXP-IDA|W|Inferred from direct assay] 34822841, Weak b1839 ECK120003600 yebZ b1840 1923719 1924591 reverse CopD family protein 23818864, b1840 ECK120003601 yobA b1841 1924595 1924969 reverse copper-binding protein [EXP-IDA|W|Inferred from direct assay] 23818864,34822841, Weak b1841 ECK120001461 holE b1842 1925108 1925338 forward DNA polymerase III subunit θ 10373010,12667053,15459336,18663010,23580545,8702818,9515927, b1842 ECK120003602 yobB b1843 1925440 1926096 forward putative carbon-nitrogen hydrolase family protein YobB 24391520, b1843 ECK120003603 exoX b1844 1926120 1926782 forward exonuclease X [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IGI|W|Inferred from genetic interaction] 10514496,11381137,11418610,12538867, Weak b1844 ECK120000993 ptrB b1845 1926779 1928839 reverse oligopeptidase B 1447164,15948139,7845209,9533626, b1845 ECK120001740 yebE b1846 1929048 1929707 reverse DUF533 domain-containing inner membrane protein YebE b1846 ECK120001741 yebF b1847 1930034 1930390 reverse secreted protein YebF 24391520, b1847 ECK120001742 yebG b1848 1930457 1930747 reverse DNA damage-inducible protein YebG [EXP-IEP|W|Inferred from expression pattern] 11897025,17121995,17214507,30857727,30904393,9368369, Weak b1848 ECK120001743 purT b1849 1930881 1932059 forward phosphoribosylglycinamide formyltransferase 2 b1849 ECK120000250 eda b1850 1932115 1932756 reverse KHG/KDPG aldolase 11946217,1624451,1885506,8344525,9503620, b1850 ECK120000251 edd b1851 1932793 1934604 reverse phosphogluconate dehydratase 1624451,1885506,4869213,8344525, b1851 ECK120001199 zwf b1852 1934839 1936314 reverse NADP-dependent glucose-6-phosphate dehydrogenase 10395749,10564484,1097391,11001586,12889026,12913009,1312800,14444199,14511906,14963616,15158258,15286986,15448692,16233247,16549675,1692736,16997589,1704005,1723138,18669258,18823050,1885506,20167619,2043108,20621143,20667837,20679215,21451587,21538115,22198407,24223390,2472381,24930895,26211962,2687089,26960359,2825185,29307493,3025682,368027,4393658,4560065,4564298,4582389,4869213,4920136,4929885,6381229,6400649,776952,7973728, b1852 ECK120002406 yebK b1853 1936652 1937521 forward DNA-binding transcriptional repressor YebK [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host],[COMP-AINF-SEQ-ORTHOLOGY|W|Automated inference of function by sequence orthology] 10734204,15556475,21849503,26121029, Strong b1853 ECK120000794 pykA b1854 1937649 1939091 forward pyruvate kinase 2 b1854 ECK120000607 lpxM b1855 1939222 1940193 reverse Lipid A biosynthesis myristoyltransferase b1855 ECK120000011 mepM b1856 1940313 1941635 reverse peptidoglycan endopeptidase MepM 30940749,32393643, b1856 ECK120003604 znuA b1857 1941651 1942583 reverse Zn ABC transporter periplasmic binding protein b1857 ECK120003605 znuC b1858 1942662 1943417 forward Zn ABC transporter ATP binding subunit b1858 ECK120002236 znuB b1859 1943414 1944199 forward Zn ABC transporter membrane subunit b1859 ECK120004476 ruvB b1860 1944346 1945356 reverse Holliday junction branch migration complex subunit RuvB b1860 ECK120004475 ruvA b1861 1945365 1945976 reverse Holliday junction branch migration complex subunit RuvA 10089419,11080172,15299982,15556943,16324713,31767757,9000618, b1861 ECK120048856 yobI b4677 1946115 1946180 reverse uncharacterized protein YobI b4677 ECK120001120 yebB b1862 1946251 1946853 forward putative papain-like amidase YebB b1862 ECK120000914 ruvC b1863 1946855 1947376 reverse crossover junction endodeoxyribonuclease RuvC 30664685, b1863 ECK120001121 yebC b1864 1947411 1948151 reverse putative transcriptional regulator YebC b1864 ECK120001122 nudB b1865 1948180 1948632 reverse dihydroneopterin triphosphate diphosphatase 16754998,26052683,29551348,30061932, b1865 ECK120000093 aspS b1866 1948750 1950522 reverse aspartate—tRNA ligase 23275545,342244, b1866 ECK120002245 yecD b1867 1950832 1951398 forward isochorismatase family protein YecD b1867 ECK120002246 yecE b1868 1951395 1952213 forward DUF72 domain-containing protein YecE b1868 ECK120003606 yecN b1869 1952266 1952661 forward MAPEG family inner membrane protein YecN b1869 ECK120003607 cmoA b1870 1952702 1953445 forward carboxy--adenosyl-L-methionine synthase b1870 ECK120003608 cmoB b1871 1953442 1954413 forward tRNA U34 carboxymethyltransferase b1871 ECK120003609 torZ b1872 1954578 1957007 reverse trimethylamine -oxide reductase 2 11004177, b1872 ECK120003610 torY b1873 1957032 1958132 reverse cytochrome quinol dehydrogenase TorY 11004177, b1873 ECK125165376 micL b4717 1958441 1958520 reverse small regulatory RNA MicL-S [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 14622403,24722986,25030700,28373273, Weak b4717 ECK120003611 cutC b1874 1958520 1959266 reverse PF03932 family protein CutC b1874 ECK120003612 yecM b1875 1959280 1959846 reverse putative metal-binding enzyme YecM [COMP-HINF|W|Inferred by a human based on computational evidence] 12660999, Weak b1875 ECK120000067 argS b1876 1960062 1961795 forward arginine—tRNA ligase 10333292,12007009,12035052,12058187,12114958,12174253,12325364,12325365,1708669,30773,318645,320192,4562386,4904510,4939770,4939781,64171,7042510,8524650,8797857, b1876 ECK125286403 yecV b4778 1961837 1961881 reverse protein YecV b4778 ECK120003613 yecT b1877 1961972 1962460 forward protein YecT 27732863, b1877 ECK120003614 flhE b1878 1962580 1962972 reverse flagellar protein FlhE [COMP-HINF-SEQ-ORTHOLOGY|W|Human inference of function by sequence orthology],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 22435757, Weak b1878 ECK120002690 flhA b1879 1962972 1965050 reverse flagellar biosynthesis protein FlhA 21244534, b1879 ECK120003615 flhB b1880 1965043 1966191 reverse flagellar biosynthesis protein FlhB b1880 ECK120000147 cheZ b1881 1966393 1967037 reverse chemotaxis protein CheZ 12644507,19424426,19502407,3313398,7623663,8305438,8557654,8557655,8631757,8639527,8816756,8820640,9045846, b1881 ECK120000146 cheY b1882 1967048 1967437 reverse chemotaxis protein CheY 10388784,10393292,10819997,11052668,11279165,12940980,14741223,1482126,15236585,17050920,17050923,17628147,17655236,18801331,20398208,20615986,21539787,2157156,22494339,23905870,24692593,25388160,27589219,27672145,2832069,28389957,3185734,33198296,34521846,6090423,7699720,7855419,8098993,8251514,8632450,9115243,9437425,9613844,9636149,9642190,9671552,9687492,9753454, b1882 ECK120000143 cheB b1883 1967452 1968501 reverse protein-glutamate methylesterase/protein glutamine deamidase 11669626,15306010,16030204,2661528,3007436,3056911,3076082,353036,3897203,6458812,6775692, b1883 ECK120000144 cheR b1884 1968504 1969364 reverse chemotaxis protein methyltransferase 10464232,1105570,324984,3510184,3553150,376504,6307970,6775692,6813329,6993459,7016848,7034965,770453, b1884 ECK120000976 tap b1885 1969383 1970984 reverse methyl-accepting chemotaxis protein Tap b1885 ECK120000977 tar b1886 1971030 1972691 reverse methyl-accepting chemotaxis protein Tar b1886 ECK120002614 C0465 1972739 1972816 forward ECK120000145 cheW b1887 1972836 1973339 reverse chemotaxis protein CheW [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ] 10972797,1326408,1860813,21463637,23950985,2682657,31925330,3510184,353036,3553150,8456299, Weak b1887 ECK120000142 cheA b1888 1973360 1975324 reverse chemotaxis protein CheA [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 10029518,11923283,12119289,12644507,15170328,15572451,15766267,16104748,16621823,19502407,21642453,22740268,23668882,23802570,24163342,2670907,29483161,31501279,31893220,31925330,3553150,6382257,7045071,7592359,8011654,8021168,8555213,8820640,8943256,8955292,9006039,9287011, b1888 ECK120000142 cheA b1888 1973360 1975324 reverse chemotaxis protein CheA(S) [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 10029518,11923283,12119289,12644507,15170328,15572451,15766267,16104748,16621823,19502407,21642453,22740268,23668882,23802570,24163342,2670907,29483161,31501279,31893220,31925330,3553150,6382257,7045071,7592359,8011654,8021168,8555213,8820640,8943256,8955292,9006039,9287011, Weak b1888 ECK120000595 motB b1889 1975329 1976255 reverse motility protein B [EXP-IMP|W|Inferred from mutant phenotype] 10704303,10836503,10894732,11669642,11669643,12628250,2061285,24550452,29573373,30069936,30927553,6374467,6764039,8057857, Weak b1889 ECK120000594 motA b1890 1976252 1977139 reverse motility protein A [EXP-IMP|W|Inferred from mutant phenotype] 10348868,10704303,10836503,10894732,11669642,12628250,14705928,14705929,16698936,16971952,17052729,1719217,18834143,1938906,2193926,23216828,24550452,26216959,28389950,2849208,29573373,30069936,7619816,7643400,7644518,7892209,8627625,8757288,8892808,9344750, Weak b1890 ECK125303725 motR b4828 1977208 1977302 reverse small RNA MotR b4828 ECK120000313 flhC b1891 1977266 1977844 reverse DNA-binding transcriptional dual regulator FlhC 12144778,7961507, b1891 ECK120000314 flhD b1892 1977847 1978197 reverse DNA-binding transcriptional dual regulator FlhD 12144778,7961507, b1892 ECK120023915 insAB5 1978518 1979215 reverse InsAB' transposase ECK120003616 insB5 b1893 1978518 1979021 reverse IS1 protein InsB b1893 ECK120003617 insA5 b1894 1978940 1979215 reverse IS1 protein InsA b1894 ECK120003618 uspC b1895 1979753 1980181 forward universal stress protein C b1895 ECK120001689 otsA b1896 1980188 1981612 reverse trehalose-6-phosphate synthase 11162529,16740928,17292861,19220470,20217281,20400481,22036231,22952665,23831895,25307558, b1896 ECK120001690 otsB b1897 1981587 1982387 reverse trehalose-6-phosphate phosphatase 10831428,11162529,1651549,16740928,17292861,20217281,20400481,22036231,23376594,23831895,8045430, b1897 ECK120000055 araH b4460 1982554 1983540 reverse arabinose ABC transporter membrane subunit b1898,b1899,b4460 ECK120000054 araG b1900 1983555 1985069 reverse arabinose ABC transporter ATP binding subunit b1900 ECK120000053 araF b1901 1985139 1986128 reverse arabinose ABC transporter periplasmic binding protein 7024251, b1901 ECK120003619 ftnB b1902 1986925 1987428 forward putative ferritin-like protein b1902 ECK120003620 Phantom Gene b1903 1987444 1987782 forward b1903 ECK120016307 yecJ b4537 1987507 1987758 reverse DUF2766 domain-containing protein YecJ b4537 ECK120002615 isrB b4434 1987839 1987998 reverse b4434 ECK120048865 azuC b4663 1987873 1987959 reverse uncharacterized protein AzuC b4663 ECK120003621 yecR b1904 1988222 1988545 forward lipoprotein YecR 24391520,32053772, b1904 ECK120000912 ftnA b1905 1988716 1989213 forward ferritin iron storage protein 22094925, b1905 ECK120003622 yecH b1906 1989251 1989490 reverse DUF2492 domain-containing protein YecH b1906 ECK120001030 tyrP b1907 1989681 1990892 forward tyrosine:H symporter b1907 ECK120001123 yecA b1908 1990954 1991619 reverse uncharacterized iron-binding protein YecA b1908 ECK125229289 3'ETS-leuZ b4759 1991748 1991814 reverse small regulatory RNA 3'ETS [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 25891076,30061117, Weak b4759 ECK120002496 leuZ b1909 1991815 1991901 reverse tRNA-Leu(UAA) [AS-TAS|W|Traceable author statement] 7033244, Weak b1909 ECK120004450 cysT b1910 1991914 1991987 reverse tRNA-Cys(GCA) [AS-TAS|W|Traceable author statement] 7033244, Weak b1910 ECK120002481 glyW b1911 1992042 1992117 reverse tRNA-Gly(GCC) b1911 ECK120000698 pgsA b1912 1992269 1992817 reverse CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase 2999767, b1912 ECK120001052 uvrC b1913 1992874 1994706 reverse UvrABC excision nuclease subunit C 32470300,33382157, b1913 ECK120001124 uvrY b1914 1994703 1995359 reverse DNA-binding transcriptional activator UvrY [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[EXP-IEP|W|Inferred from expression pattern],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 11022030,12193630,12533459, Strong b1914 ECK125276521 yecU b4752 1995655 1995831 forward protein YecU b4752 ECK120002407 yecF b1915 1995818 1996042 forward DUF2594 domain-containing protein YecF b1915 ECK120000924 sdiA b1916 1996110 1996832 reverse DNA-binding transcriptional dual regulator SdiA [EXP|W|Inferred from experiment] Weak b1916 ECK125135297 sdsN b4719 1996921 1997057 forward small regulatory RNA SdsN [EXP-IMP|W|Inferred from mutant phenotype] 27166377, Weak b4719 ECK120002221 tcyN b1917 1997062 1997814 reverse cystine ABC transporter ATP binding subunit 11544237,9495757, b1917 ECK120003623 tcyL b1918 1997811 1998479 reverse cystine ABC transporter membrane subunit 25139244, b1918 ECK120003624 dcyD b1919 1998494 1999480 reverse D-cysteine desulfhydrase 13198265, b1919 ECK120003625 tcyJ b1920 1999585 2000385 reverse cystine ABC transporter periplasmic binding protein 4564569, b1920 ECK120001325 fliZ b1921 2000473 2001024 reverse DNA-binding transcriptional regulator FliZ [EXP-IMP|W|Inferred from mutant phenotype] 18765794, Weak b1921 ECK120001324 fliA b1922 2001070 2001789 reverse RNA polymerase sigma factor FliA b1922 ECK125303717 fliX b4827 2001912 2002106 reverse small RNA FliX b4827 ECK120000315 fliC b1923 2002110 2003606 reverse flagellar filament structural protein 33643229, b1923 ECK120000832 fliD b1924 2003872 2005278 forward flagellar filament capping protein [EXP-IMP|W|Inferred from mutant phenotype] 25350000,28179186, Weak b1924 ECK120001355 fliS b1925 2005303 2005713 forward flagellar biosynthesis protein FliS [EXP-IMP|W|Inferred from mutant phenotype] 25350000, Weak b1925 ECK120001356 fliT b1926 2005713 2006078 forward flagellar biosynthesis protein FliT [EXP-IMP|W|Inferred from mutant phenotype] 1527488, Weak b1926 ECK120001354 amyA b1927 2006156 2007643 forward α-amylase b1927 ECK120001602 yedD b1928 2007677 2008090 reverse lipoprotein YedD 24391520,32053772, b1928 ECK120001603 yedE b1929 2008277 2009482 forward putative selenium transporter YedE b1929 ECK120001604 yedF b1930 2009479 2009712 forward putative sulfurtransferase YedF [COMP-HINF|W|Inferred by a human based on computational evidence] 11854485, Weak b1930 ECK120001605 yedK b1931 2009821 2010489 forward genome maintenance protein 23945014,29020633,31270474, b1931 ECK120003626 yedL b1932 2010600 2011079 forward putative acetyltransferase YedL b1932 ECK120003629 yedN b4495 2011223 2012351 reverse putative type III secreted effector, N-terminal fragment b1933,b1934,b1935,b4495 ECK120003630 intG b1936 2012502 2012780 forward putative defective phage integrase b1936 ECK120001317 fliE b1937 2012700 2013014 reverse flagellar protein FliE [COMP-HINF-ORTHOLOGY-EXP|W|Human inference of function based on ortholog with experimental function in closely related strain or species.] 1551848,7007337,8371104, Weak b1937 ECK120001318 fliF b1938 2013229 2014887 forward flagellar basal-body MS-ring and collar protein [AS-TAS|W|Traceable author statement] 12500982,6993282,7007337, Weak b1938 ECK120001598 fliG b1939 2014880 2015875 forward flagellar motor switch protein FliG 15126479,16077109,25762339,29573373,30279682,34707181,8550421,8631704,9102466,9356251, b1939 ECK120001599 fliH b1940 2015868 2016554 forward flagellar biosynthesis protein FliH b1940 ECK120002692 fliI b1941 2016554 2017927 forward flagellar export ATPase FliI b1941 ECK120002693 fliJ b1942 2017946 2018389 forward flagellar biosynthesis protein FliJ b1942 ECK120002694 fliK b1943 2018386 2019513 forward flagellar hook-length control protein [EXP|W|Inferred from experiment] 28557186, Weak b1943 ECK120000316 fliL b1944 2019618 2020082 forward flagellar protein FliL [EXP-IMP|W|Inferred from mutant phenotype] 18284590,25714720,28717192,7007337, Weak b1944 ECK120000317 fliM b1945 2020087 2021091 forward flagellar motor switch protein FliM 22830299,7768858, b1945 ECK120000318 fliN b1946 2021088 2021501 forward flagellar motor switch protein FliN 7768859, b1946 ECK120001202 fliO b1947 2021504 2021869 forward flagellar biosynthesis protein FliO b1947 ECK120001900 fliP b1948 2021869 2022606 forward flagellar biosynthesis protein FliP 29076571, b1948 ECK120001901 fliQ b1949 2022616 2022885 forward flagellar biosynthesis protein FliQ b1949 ECK120001902 fliR b1950 2022893 2023678 forward flagellar biosynthesis protein FliR b1950 ECK120000811 rcsA b1951 2023968 2024591 forward DNA-binding transcriptional activator RcsA 1943696,23667443,2404948,32094588,8576059, b1951 ECK120003631 dsrB b1952 2024635 2024823 reverse protein DsrB b1952 ECK120003632 yodD b1953 2024986 2025213 forward stress-induced protein [EXP-IMP|W|Inferred from mutant phenotype] 19919618, Weak b1953 ECK120003633 dsrA b1954 2025223 2025313 reverse small regulatory RNA DsrA [EXP-IMP|W|Inferred from mutant phenotype] 12069726,25262352,25582129,30287822,32845055, Weak b1954 ECK120003634 yedP b1955 2025511 2026326 forward putative mannosyl-3-phosphoglycerate phosphatase b1955 ECK120003635 dgcQ b1956 2026323 2028017 reverse diguanylate cyclase DgcQ 29469946,34903045, b1956 ECK120003636 yodC b1957 2028188 2028370 reverse protein YodC b1957 ECK120002367 yedI b1958 2028449 2029366 reverse DUF808 domain-containing inner membrane protein YedI b1958 ECK120001125 yedA b1959 2029539 2030459 forward putative transporter YedA 15466053,17025177,31438868, b1959 ECK120001057 vsr b1960 2030448 2030918 reverse DNA mismatch endonuclease Vsr [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10982859,11591694,12399478,1337970,1944537,19556224,8177221, Strong b1960 ECK120000205 dcm b1961 2030899 2032317 reverse DNA-cytosine methyltransferase 1091619,22640,2425255,2435706,2452347,2527357,2825167,2948873,2981756,2990558,3011742,3301808,3323525,3894024,4353870,6233606,6254852,6263867,6280874,6296768, b1961 ECK120002368 yedJ b1962 2032384 2033079 reverse putative HD superfamily phosphohydrolase YedJ b1962 ECK120003637 drpB b1963 2033119 2033421 reverse cell division protein DrpB [EXP-IGI|W|Inferred from genetic interaction] 32900831, Weak b1963 ECK120029424 rseX b4603 2033649 2033739 forward small regulatory RNA RseX [EXP-IDA|W|Inferred from direct assay] 16513633,25724987,30287822,34327153, Weak b4603 ECK120003638 yedS b4496 2034051 2035243 forward putative outer membrane protein YedS, N-terminal fragment 23318808,27431906, b1964,b1965,b1966,b4496 ECK120003641 hchA b1967 2035835 2036686 forward protein/nucleic acid deglycase 1 12077448, b1967 ECK120003642 hprS b1968 2036794 2038152 reverse sensor histidine kinase HprS 12897016,24391520, b1968 ECK120003643 hprR b1969 2038152 2038823 reverse DNA-binding transcriptional dual regulator HprR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[COMP-HINF-ISM|W|Inferred from Sequence Model],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10734204,15556475,25568260, Strong b1969 ECK120003644 hiuH b1970 2038956 2039369 forward hydroxyisourate hydrolase / transthyretin-related protein b1970 ECK120003645 msrP b1971 2039478 2040482 forward protein-L-methionine sulfoxide reductase catalytic subunit MsrP b1971 ECK120003646 msrQ b1972 2040483 2041118 forward membrane-bound flavocytochrome MsrQ 28028176,34550690, b1972 ECK120003647 zinT b1973 2041375 2042025 forward metal-binding protein ZinT [AS-HYPO|W|Author hypothesis],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 12077457,12900028,12909634,15802252,16814929,18302792,19377097,21338480,26660914, Weak b1973 ECK120003648 yodB b1974 2042368 2042898 forward putative cytochrome b561 YodB 24391520, b1974 ECK120002536 serU b1975 2043468 2043557 reverse tRNA-Ser(CGA) [AS-TAS|W|Traceable author statement] 7033244, Weak b1975 ECK120003649 mtfA b1976 2043651 2044448 forward Mlc titration factor [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IPI|W|Inferred from physical interaction],[EXP-IGI|W|Inferred from genetic interaction] 16855233,22178967, Weak b1976 ECK120002463 asnT b1977 2044549 2044624 forward tRNA-Asn(GUU) [AS-TAS|W|Traceable author statement] 11946478,7033244, Weak b1977 ECK120003650 yeeJ b1978 2044938 2052014 forward inverse autotransporter adhesin [EXP-IMP|W|Inferred from mutant phenotype] 15659678,17067927, Weak b1978 ECK120003652 yeeL b4497 2052276 2053328 reverse putative glycosyltransferase, N-terminal fragment b1979,b1980,b4497 ECK120003653 shiA b1981 2053643 2054959 forward shikimate:H symporter b1981 ECK120000035 amn b1982 2055061 2056515 forward AMP nucleosidase 2690948,6327703, b1982 ECK120003654 yeeN b1983 2056858 2057574 forward putative transcriptional regulator YeeN 24391520, b1983 ECK120003655 asnW b1984 2058027 2058102 reverse tRNA-Asn(GUU) [AS-TAS|W|Traceable author statement] 11946478,7033244, Weak b1984 ECK120003656 yeeO b1985 2058203 2059846 reverse FMN/FAD exporter 25482085, b1985 ECK120002464 asnU b1986 2059851 2059926 forward tRNA-Asn(GUU) [AS-TAS|W|Traceable author statement] 11946478,7033244, Weak b1986 ECK120003657 cbl b1987 2059964 2060914 reverse DNA-binding transcriptional activator Cbl [EXP|W|Inferred from experiment] Weak b1987 ECK120003658 nac b1988 2061016 2061933 reverse DNA-binding transcriptional dual regulator Nac [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[EXP-IDA|W|Inferred from direct assay],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 11121068,9495755, Strong b1988 ECK120002465 asnV b1989 2062260 2062335 forward tRNA-Asn(GUU) [AS-TAS|W|Traceable author statement] 11946478,7033244, Weak b1989 ECK120003659 ldtA b1990 2062391 2063323 reverse L,D-transpeptidase LdtA 31743648, b1990 ECK120002050 cobT b1991 2063388 2064467 reverse nicotinate-nucleotide—dimethylbenzimidazole phosphoribosyltransferase b1991 ECK120002049 cobS b1992 2064479 2065222 reverse cobalamin 5'-phosphate synthase [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 7592411, Strong b1992 ECK120002434 cobU b1993 2065219 2065764 reverse cobinamide-P guanylyltransferase / cobinamide kinase b1993 ECK125240971 yeeH b4639 2066068 2066154 reverse b4639 ECK120003660 insH6 b1994 2066305 2067285 reverse CP4-44 prophage; IS transposase and trans-activator b1994 ECK125240970 yoeG b4640 2067360 2067892 reverse b4640 ECK125240969 yoeH b4641 2068261 2068419 reverse b4641 ECK120003662 insD3 b1996 2068952 2069857 reverse CP4-44 prophage; IS2 insertion element protein InsB b1996 ECK120023919 insCD3 2068952 2070180 reverse IS2 element transposase InsAB' ECK120003663 insC3 b1997 2069815 2070180 reverse CP4-44 prophage; IS2 insertion element repressor InsA b1997 ECK120003665 yeeP b1999 2070786 2071211 forward CP4-44 prophage; putative GTP-binding protein b1999 ECK120002616 isrC b4435 2071317 2071511 forward CP4-44 prophage; small RNA IsrC b4435 ECK120003666 flu b2000 2071539 2074658 forward CP4-44 prophage; self recognizing antigen 43 (Ag43) autotransporter [EXP|W|Inferred from experiment] 10094691,24039985, Weak b2000 ECK120003667 yeeR b2001 2074779 2076311 forward CP4-44 prophage; inner membrane protein YeeR b2001 ECK120003668 yeeS b2002 2076308 2076754 forward CP4-44 prophage; RadC-like JAB domain-containing protein YeeS b2002 ECK120003669 yeeT b2003 2076817 2077038 forward CP4-44 prophage; DUF987 domain-containing protein YeeT b2003 ECK120003670 cbeA b2004 2077112 2077480 forward CP4-44 prophage; cytoskeleton bundling-enhancing antitoxin CbeA [EXP-IDA|W|Inferred from direct assay],[EXP-IGI|W|Inferred from genetic interaction] 14594833,22515815, Weak b2004 ECK120003671 cbtA b2005 2077569 2077943 forward CP4-44 prophage; cytoskeleton-binding toxin CbtA [EXP|W|Inferred from experiment],[EXP-IDA|W|Inferred from direct assay] 14594833,21166897, Weak b2005 ECK120003672 yeeW b2006 2077940 2078134 forward CP4-44 prophage; putative uncharacterized protein YeeW b2006 ECK125240968 yoeD b4642 2078549 2078677 reverse b4642 ECK120016308 yoeF b4538 2078575 2078931 forward CP4-44 prophage; putative uncharacterized protein YoeF b4538 ECK120003673 tmaR b2007 2079032 2079361 reverse PTS system regulator TmaR [EXP-IMP|W|Inferred from mutant phenotype] 24391520,33376208,9868784, Weak b2007 ECK125303706 yoeJ b4818 2079427 2079477 reverse protein YoeJ b4818 ECK120001821 yeeA b2008 2079533 2080591 reverse putative transporter YeeA 31438868, b2008 ECK120001822 sbmC b2009 2080789 2081262 reverse DNA gyrase inhibitor [EXP|W|Inferred from experiment] Weak b2009 ECK120001823 dacD b2010 2081381 2082547 reverse D-alanyl-D-alanine carboxypeptidase DacD 12444970,12562782,12644487,15466028,16855223,17026754,28900026,30233559, b2010 ECK120000915 sbcB b2011 2082756 2084183 forward exodeoxyribonuclease I [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IDA-PART-PURIFIED-PROTEIN|W|Assay of partially-purified protein ],[EXP-IGI|W|Inferred from genetic interaction] 10672041,1329027,14235546,2029968,25368150,2834321,33382157,3911022,6296059,6343375,7700238,783113, Weak b2011 ECK120001824 tsuB b2012 2084226 2084453 reverse putative thiosulfate sulfurtransferase [EXP-IMP|W|Inferred from mutant phenotype] 18202662,22984254,30880290,32779574, Weak b2012 ECK120001825 tsuA b2013 2084467 2085525 reverse thiosulfate transporter 18202662,20545747,22984254, b2013 ECK120001826 plaP b2014 2085704 2087062 reverse putrescine:H symporter PlaP b2014 ECK120048855 yoeI b4678 2087052 2087114 reverse uncharacterized protein YoeI b4678 ECK120003674 yeeY b2015 2087329 2088258 reverse putative DNA-binding transcriptional regulator YeeY [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b2015 ECK120003675 yeeZ b2016 2088304 2089128 reverse putative epimerase YeeZ 17664315,31608580, b2016 ECK120002629 yoeB b4539 2089211 2089465 reverse ribosome-dependent mRNA interferase toxin YoeB b4539 ECK120002397 yefM b2017 2089462 2089713 reverse YefM antitoxin of the YoeB-YefM toxin-antitoxin pair and DNA binding transcriptional repressor b2017 ECK120001243 hisL b2018 2089996 2090046 forward operon leader peptide b2018 ECK120000442 hisG b2019 2090192 2091091 forward ATP phosphoribosyltransferase b2019 ECK120000440 hisD b2020 2091097 2092401 forward histidinal/histidinol dehydrogenase b2020 ECK120000439 hisC b2021 2092398 2093468 forward histidinol-phosphate aminotransferase b2021 ECK120000438 hisB b2022 2093468 2094535 forward imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase b2022 ECK120000443 hisH b2023 2094535 2095125 forward imidazole glycerol phosphate synthase subunit HisH b2023 ECK120000437 hisA b2024 2095125 2095862 forward 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase b2024 ECK120000441 hisF b2025 2095844 2096620 forward imidazole glycerol phosphate synthase subunit HisF b2025 ECK120000444 hisI b2026 2096614 2097225 forward putative bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase b2026 ECK120003676 wzzB b2027 2097321 2098301 reverse O-antigen co-polymerase 25307743,8606163,9383197, b2027 ECK120003677 ugd b2028 2098447 2099613 reverse UDP-glucose 6-dehydrogenase b2028 ECK120000404 gnd b2029 2099862 2101268 reverse 6-phosphogluconate dehydrogenase, decarboxylating 1090352,1102472,11056062,12670695,14963616,15158258,15221231,15453191,16742809,172907,17672300,1938920,2043108,2050640,20700606,22454498,22823407,25178796,26211962,2677599,2826398,3275621,3306673,344039,3552883,368027,385598,4577744,4583246,4590471,4869213,4942760,6245062,6259121,6392014,7021316,7031648,780123,8001789,9503620,9866203, b2029 ECK125256965 gndA 2100863 2101027 reverse heat shock-induced protein GndA 29039649, ECK120003678 insH7 b2030 2101895 2102875 reverse IS transposase and trans-activator b2030 ECK120001910 wbbK b2032 2103391 2104509 reverse putative glycosyltransferase WbbK b2032 ECK120001909 wbbJ b2033 2104494 2105084 reverse putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ b2033 ECK120001908 wbbI b2034 2105065 2106057 reverse β-1,6-galactofuranosyltransferase WbbI 19836012, b2034 ECK120001907 wbbH b2035 2106060 2107226 reverse putative O-antigen polymerase [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 7517391, Weak b2035 ECK120001906 glf b2036 2107226 2108329 reverse UDP-galactopyranose mutase b2036 ECK120001905 rfbX b2037 2108337 2109584 reverse polyisoprenol-linked O16-antigen repeat unit flippase b2037 ECK120001904 rfbC b2038 2109581 2110138 reverse dTDP-4-dehydrorhamnose 3,5-epimerase 10089454, b2038 ECK120001903 rfbA b2039 2110138 2111019 reverse glucose-1-phosphate thymidylyltransferase 1 b2039 ECK120002272 rfbD b2040 2111077 2111976 reverse dTDP-4-dehydrorhamnose reductase 23072384,28374071, b2040 ECK120002273 rfbB b2041 2111976 2113061 reverse dTDP-glucose 4,6-dehydratase 1 b2041 ECK120003679 galF b2042 2113434 2114327 reverse UTP:glucose-1-phosphate uridylyltransferase, low activity [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 12581358,8759852,8971705, Weak b2042 ECK120003680 wcaM b2043 2114502 2115896 reverse putative colanic acid biosynthesis protein WcaM 12192075, b2043 ECK120003681 wcaL b2044 2115907 2117127 reverse putative colanic acid biosynthesis glycosyl transferase WcaL b2044 ECK120003682 wcaK b2045 2117124 2118404 reverse colanic acid biosynthesis pyruvyl transferase WcaK b2045 ECK120003683 wzxC b2046 2118680 2120158 reverse colanic acid repeat unit flippase 34159784,6090411,9004408, b2046 ECK120003684 wcaJ b2047 2120160 2121554 reverse UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase 26833417,32094588, b2047 ECK120000158 cpsG b2048 2121609 2122979 reverse phosphomannomutase b2048 ECK120000157 cpsB b2049 2123084 2124520 reverse mannose-1-phosphate guanylyltransferase b2049 ECK120001724 wcaI b2050 2124523 2125746 reverse colanic acid biosynthesis fucosyltransferase WcaI b2050 ECK120001723 gmm b2051 2125743 2126222 reverse GDP-mannose mannosyl hydrolase b2051 ECK120001722 fcl b2052 2126225 2127190 reverse GDP-L-fucose synthase b2052 ECK120001721 gmd b2053 2127193 2128314 reverse GDP-mannose 4,6-dehydratase b2053 ECK120003685 wcaF b2054 2128340 2128888 reverse colanic acid biosynthesis acetyltransferase WcaF b2054 ECK120003686 wcaE b2055 2128904 2129650 reverse GDP-Fuc:2/3--Ac-α-L-Fuc-(1→3)-α-D-Glc-PP-Und α-(1,4)-fucosyltransferase b2055 ECK120003687 wcaD b2056 2129661 2130878 reverse colanic acid polymerase 11371548, b2056 ECK120003688 wcaC b2057 2130853 2132070 reverse colanic acid biosynthesis galactosyltransferase WcaC b2057 ECK120003689 wcaB b2058 2132067 2132555 reverse colanic acid biosynthesis acetyltransferase WcaB b2058 ECK120003690 wcaA b2059 2132558 2133397 reverse UDP-glucuronate:2-3)-β-D-Glc-PP-Und β-(1,3)-glucuronosyltranferase 32094588, b2059 ECK120003691 wzc b2060 2133490 2135652 reverse protein-tyrosine kinase Wzc 33355134,8759852, b2060 ECK120003692 wzb b2061 2135655 2136098 reverse protein-tyrosine phosphatase 8759852, b2061 ECK120003693 wza b2062 2136104 2137243 reverse outer membrane polysaccharide export protein Wza 19236919,32053772, b2062 ECK120003694 yegH b2063 2137902 2139485 forward inner membrane protein YegH 31438868, b2063 ECK120001330 asmA b2064 2139759 2141612 reverse putative assembly protein AsmA [EXP-IMP|W|Inferred from mutant phenotype] 34781743,7476172,8576061, Weak b2064 ECK120001383 dcd b2065 2141634 2142215 reverse dCTP deaminase 17827303,19251902,27718375,3897790,7891665,8710514, b2065 ECK120001644 udk b2066 2142307 2142948 reverse uridine/cytidine kinase 8366067, b2066 ECK120002259 dgcE b2067 2143266 2146583 forward putative diguanylate cyclase DgcE b2067 ECK120001200 alkA b2068 2146692 2147540 reverse DNA-3-methyladenine glycosylase 2 [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 25537480,30617079,6287922, Weak b2068 ECK120002088 yegD b2069 2147674 2149026 forward HSP70 family protein YegD [COMP-HINF|W|Inferred by a human based on computational evidence] 10574456, Weak b2069 ECK120003695 yegI b2070 2149039 2150985 reverse putative serine/threonine-protein kinase YegI b2070 ECK120003696 yegJ b2071 2151185 2151646 forward DUF2314 domain-containing protein YegJ 24391520, b2071 ECK120003697 pphC b2072 2151711 2152472 reverse protein-serine/threonine phosphatase PphC 29967116, b2072 ECK120003698 yegL b2073 2152469 2153128 reverse IPR002035 domain-containing protein YegL b2073 ECK120002595 sibA b4436 2153311 2153454 forward small RNA SibA b4436 ECK120035075 ibsA b4667 2153349 2153408 reverse toxic peptide IbsA [EXP-IMP|W|Inferred from mutant phenotype] 18710431, Weak b4667 ECK120002596 sibB b4437 2153646 2153781 forward small RNA SibB [EXP-IMP|W|Inferred from mutant phenotype] 18710431, Weak b4437 ECK120035074 ibsB b4668 2153681 2153737 reverse putative toxic peptide IbsB [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 18710431, Weak b4668 ECK120003699 mdtA b2074 2154016 2155263 forward multidrug efflux pump membrane fusion protein MdtA 31438868, b2074 ECK120003700 mdtB b2075 2155263 2158385 forward multidrug efflux pump RND permease subunit MdtB 11566977,31438868, b2075 ECK120003701 mdtC b2076 2158386 2161463 forward multidrug efflux pump RND permease subunit MdtC 31438868, b2076 ECK120002037 mdtD b2077 2161464 2162879 forward putative multidrug efflux pump MdtD b2077 ECK120001565 baeS b2078 2162876 2164279 forward sensor histidine kinase BaeS 12366850,12618449, b2078 ECK120001566 baeR b2079 2164276 2164998 forward DNA-binding transcriptional activator BaeR [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 12107134,1482126,2157156,7699720,8098993, Weak b2079 ECK120003702 yegP b2080 2165189 2165521 forward DUF1508 domain-containing protein YegP b2080 ECK120003703 trhP b2081 2165668 2167029 forward tRNA wobble base hydroxylation protein TrhP [EXP-IMP|W|Inferred from mutant phenotype] 31253794,31358606, Weak b2081 ECK120002589 cyaR b4438 2167114 2167200 forward small regulatory RNA CyaR [EXP-IMP|W|Inferred from mutant phenotype] 18619465,18978044,20627350,30287822, Weak b4438 ECK120003704 ogrK b2082 2167302 2167520 reverse prophage P2 late control protein OgrK [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15556475,1597424,23822838, Strong b2082 ECK120003705 yegZ b2083 2167602 2167820 reverse phage protein D b2083 ECK120003706 Phantom Gene b2084 2167735 2168001 reverse b2084 ECK120003707 yegR b2085 2167989 2168306 reverse uncharacterized protein YegR b2085 ECK120003708 yegS b2086 2168712 2169611 forward lipid kinase YegS 23822838, b2086 ECK120003709 insE5 b2088 2170236 2170535 forward IS3 element protein InsE b2088 ECK120023907 insEF5 2170236 2171398 forward IS3 element transposase ECK120003710 insF5 b2089 2170532 2171398 forward IS3 element protein InsF b2089 ECK120002277 gatD b2091 2171833 2172873 reverse galactitol-1-phosphate 5-dehydrogenase b2091 ECK120002276 gatC b2092 2172921 2174278 reverse galactitol-specific PTS enzyme IIC component b2092 ECK120002275 gatB b2093 2174282 2174566 reverse galactitol-specific PTS enzyme IIB component b2093 ECK120002274 gatA b2094 2174597 2175049 reverse galactitol-specific PTS enzyme IIA component b2094 ECK120003711 gatZ b2095 2175059 2176321 reverse putative tagatose-1,6-bisphosphate aldolase 2 chaperone [EXP-IMP|W|Inferred from mutant phenotype] 11976750, Weak b2095 ECK120002278 gatY b2096 2176350 2177204 reverse tagatose-1,6-bisphosphate aldolase 2 16945443,17608696,7772602,8955298, b2096 ECK120003712 fbaB b2097 2177512 2178564 reverse fructose-bisphosphate aldolase class I b2097 ECK120003713 yegT b2098 2178821 2180098 forward putative transporter YegT 31438868, b2098 ECK120003714 yegU b2099 2180095 2181099 forward putative ADP-ribosylglycohydrolase YegU b2099 ECK120003715 yegV b2100 2181096 2182061 forward putative sugar kinase YegV b2100 ECK120003716 yegW b2101 2182035 2182781 reverse putative DNA-binding transcriptional regulator YegW [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15556475, Weak b2101 ECK120003717 yegX b2102 2182833 2183651 reverse putative glycosyl hydrolase YegX b2102 ECK120003718 thiD b2103 2183716 2184516 reverse bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase b2103 ECK120004467 thiM b2104 2184513 2185301 reverse hydroxyethylthiazole kinase b2104 ECK120003719 rcnR b2105 2185524 2185796 reverse DNA-binding transcriptional repressor RcnR [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 16956381,17120142,19703465, Weak b2105 ECK120003720 rcnA b2106 2185917 2186741 forward Ni exporter b2106 ECK120003721 rcnB b2107 2186960 2187298 forward periplasmic protein involved in nickel/cobalt export [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[EXP-IEP|W|Inferred from expression pattern] 21665978, Strong b2107 ECK120001912 yehA b2108 2187380 2188414 reverse putative fimbrial adhesin YehA [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825, Weak b2108 ECK120001913 yehB b2109 2188430 2190910 reverse putative fimbrial usher protein YehB [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 12192075,20345943,21344461,23382825, Weak b2109 ECK120001914 yehC b2110 2190926 2191645 reverse putative fimbrial chaperone YehC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 12192075,20345943,21344461,23382825, Weak b2110 ECK120001915 yehD b2111 2191680 2192222 reverse putative fimbrial protein YehD [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825, Weak b2111 ECK120001916 yehE b2112 2192515 2192796 reverse DUF2574 domain-containing protein YehE 24391520, b2112 ECK120000604 mrp b2113 2193059 2194168 reverse P-loop NTPase family protein Mrp 1675209,8978086,9813262, b2113 ECK120000579 metG b2114 2194300 2196333 forward methionine—tRNA ligase 10829011,1097064,1107028,11945606,11945935,12234471,1280807,1329109,1372129,1447148,16233096,1675209,19383686,19894713,222589,2246241,22575034,24810463,2947897,3139093,3283733,334536,3513822,367445,371961,3902100,42539,4361287,4567120,4575301,4607017,4608416,4862767,4871905,4876744,4879640,4922213,4926130,4934682,4941204,6267070,6424668,6756915,7030381,7045381,776614,781286,8031903,8422964,8501076,9264027,9385645, b2114 ECK120001917 yehF b2115 2196474 2197298 forward PF05406 family protein YehF b2115 ECK120004458 yehH b4499 2197410 2200269 forward b2116,b2117,b4499 ECK120001918 yehI b2118 2200279 2203911 forward DUF4132 domain-containing protein YehI b2118 ECK120016310 yehK b4541 2203972 2204289 forward uncharacterized protein YehK b4541 ECK125289861 orzP 2204402 2204484 forward small RNA OrzP ECK120001919 yehL b2119 2204596 2205684 forward putative AAA+ MoxR family ATPase YehL b2119 ECK120001920 yehM b2120 2205695 2207974 forward uncharacterized protein YehM 24391520, b2120 ECK120001921 yehP b2121 2207967 2209103 forward VWA domain-containing protein YehP b2121 ECK120001922 yehQ b2122 2209100 2210944 forward SWIM zinc finger domains-containing protein YehQ b2122 ECK120001923 yehR b2123 2211225 2211686 forward DUF1307 domain-containing lipoprotein YehR 32053772, b2123 ECK120001924 yehS b2124 2211726 2212196 reverse DUF1456 domain-containing protein YehS b2124 ECK120001925 btsR b2125 2212243 2212962 reverse DNA-binding transcriptional dual regulator BtsR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 12618449,12951338, Weak b2125 ECK120001926 btsS b2126 2212959 2214644 reverse high-affinity pyruvate receptor 33721833, b2126 ECK120001927 mlrA b2127 2214866 2215597 forward DNA-binding transcriptional activator MlrA [COMP-HINF|W|Inferred by a human based on computational evidence],[EXP-IEP|W|Inferred from expression pattern],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 11489123,12775697,15556475,20874755, Strong b2127 ECK120016311 yohO b4542 2215657 2215764 forward UPF0387 family protein YohO b4542 ECK120001928 yehW b2128 2215745 2216476 reverse glycine betaine ABC transporter membrane subunit YehW b2128 ECK120001929 yehX b2129 2216481 2217407 reverse glycine betaine ABC transporter ATP binding subunit YehX b2129 ECK120001930 yehY b2130 2217400 2218557 reverse glycine betaine ABC transporter membrane subunit YehY b2130 ECK120001931 osmF b2131 2218564 2219481 reverse glycine betaine ABC transporter periplasmic binding protein OsmF b2131 ECK120001932 bglX b2132 2219692 2221989 reverse β-D-glucoside glucohydrolase, periplasmic b2132 ECK120000225 dld b2133 2222185 2223900 forward quinone-dependent D-lactate dehydrogenase 1092688,1850292,1931992,2655708,3548821,3882663,4149273,4316677,4330145,4330922,4394455,4579004,4598306,6386470,6387427,7046793,7046794,789373,795808,805139, b2133 ECK120001933 pbpG b2134 2223938 2224870 reverse peptidoglycan DD-endopeptidase PbpG [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 10383966,2676988,2692534,3042758,34382698,7785976,8063800,9324260, Weak b2134 ECK120001934 yohC b2135 2225044 2225631 reverse putative inner membrane protein b2135 ECK120001935 yohD b2136 2225801 2226379 forward DedA family protein YohD [EXP-IGI|W|Inferred from genetic interaction] 18456815, Weak b2136 ECK120001936 yohF b2137 2226509 2227270 reverse putative oxidoreductase YohF 24391520, b2137 ECK120001937 mdtQ b2139 2227323 2228758 reverse putative multidrug resistance outer membrane protein MdtQ [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 11257026,32053772, Weak b2138,b2139 ECK120048864 yohP b4679 2228982 2229065 forward uncharacterized membrane protein YohP b4679 ECK120001939 dusC b2140 2229438 2230385 reverse tRNA-dihydrouridine synthase b2140 ECK120001940 yohJ b2141 2230624 2231022 forward putative 3-hydroxypropanoate export protein YohJ b2141 ECK120001941 yohK b2142 2231019 2231714 forward putative 3-hydroxypropanoate export protein YohK 24391520, b2142 ECK120000133 cdd b2143 2231844 2232728 forward cytidine/deoxycytidine deaminase 6339482,6392823, b2143 ECK120001942 sanA b2144 2232878 2233597 forward DUF218 domain-containing protein SanA b2144 ECK120003722 yeiS b2145 2233600 2233839 forward DUF2542 domain-containing protein YeiS b2145 ECK120003723 preT b2146 2234033 2235271 forward dihydropyrimidine dehydrogenase (NAD) subunit PreT b2146 ECK120001262 preA b2147 2235265 2236500 forward dihydropyrimidine dehydrogenase (NAD) subunit PreA b2147 ECK120000587 mglC b2148 2236743 2237753 reverse D-galactose/methyl-galactoside ABC transporter membrane subunit b2148 ECK120000585 mglA b2149 2237769 2239289 reverse D-galactose/methyl-galactoside ABC transporter ATP binding subunit b2149 ECK120000586 mglB b2150 2239350 2240348 reverse D-galactose/methyl-galactoside ABC transporter periplasmic binding protein 1328650,14763860,15032747,16080150,16452309,1647202,17328569,17924684,1848243,23148479,27827455,3087946,3302609,393831,4208664,4550764,4626720,4871201,4916925,4981309,6285145,6351927,6358208,6987223,8951381, b2150 ECK120000358 galS b2151 2240628 2241668 reverse DNA-binding transcriptional dual regulator GalS [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 1619663,1900742,7934815,8416900,8982002, Weak b2151 ECK120001263 yeiB b2152 2241810 2242967 reverse DUF418 domain-containing protein YeiB b2152 ECK120001343 folE b2153 2242984 2243652 reverse GTP cyclohydrolase 1 b2153 ECK120001943 yeiG b2154 2243910 2244746 forward -lactoylglutathione hydrolase 29842925, b2154 ECK120000151 cirA b2155 2244778 2246769 reverse iron-catecholate outer membrane transporter CirA [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 19919671,20041993,33717488,6337134, Strong b2155 ECK120001308 lysP b2156 2247063 2248532 reverse lysine:H symporter 19703467,21441513,30740540,4931309,8808945, b2156 ECK120002010 yeiE b2157 2248737 2249618 reverse DNA-binding transcriptional regulator YeiE [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IPI|W|Inferred from physical interaction] 10734204,12400704,15556475,30137486, Weak b2157 ECK120001944 yeiH b2158 2249717 2250766 forward PF03601 family inner membrane protein YeiH b2158 ECK120000644 nfo b2159 2250840 2251697 forward endonuclease IV 10090748,15209514,23898172,2440861,30997305,7520446,8943004, b2159 ECK120001945 yeiI b2160 2251700 2252788 forward putative sugar kinase YeiI b2160 ECK120001946 nupX b2161 2252895 2254145 reverse putative nucleoside transporter b2161 ECK120001947 rihB b2162 2254245 2255186 reverse pyrimidine-specific ribonucleoside hydrolase RihB b2162 ECK120001948 yeiL b2163 2255355 2256014 forward DNA-binding transcriptional activator YeiL [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 11101674,9278503, Weak b2163 ECK120001949 psuT b2164 2256085 2257335 reverse putative pseudouridine transporter b2164 ECK120001950 psuG b2165 2257429 2258367 reverse pseudouridine-5'-phosphate glycosidase b2165 ECK120001590 psuK b2166 2258355 2259296 reverse putative pseudouridine kinase b2166 ECK120000330 fruA b2167 2259719 2261410 reverse fructose-specific PTS multiphosphoryl transfer protein FruA b2167 ECK120000331 fruK b2168 2261427 2262365 reverse 1-phosphofructokinase 1332910,1534139,1666389,7721070, b2168 ECK120004449 fruB b2169 2262365 2263495 reverse fructose-specific PTS multiphosphoryl transfer protein FruB 7006754, b2169 ECK120001951 setB b2170 2263863 2265044 forward sugar exporter SetB b2170 ECK120016921 yeiW b4502 2265041 2265295 reverse putative metal-chelating domain-containing protein YeiW b4502 ECK120001952 yeiP b2171 2265450 2266022 forward elongation factor P-like protein YeiP b2171 ECK120001953 yeiQ b2172 2266245 2267711 forward putative oxidoreductase YeiQ b2172 ECK120002009 yeiR b2173 2267829 2268815 forward zinc-binding GTPase YeiR [EXP-IMP|W|Inferred from mutant phenotype] 22511334, Weak b2173 ECK120003724 lpxT b2174 2268854 2269567 forward lipid A-core phosphotransferase 17511876, b2174 ECK120003725 mepS b2175 2269979 2270545 forward peptidoglycan endopeptidase/peptidoglycan L,D-carboxypeptidase 32053772,9158724, b2175 ECK120003726 pdeN b2176 2270726 2272282 forward putative c-di-GMP phosphodiesterase PdeN 29018125, b2176 ECK120001954 yejA b2177 2272364 2274178 forward putative oligopeptide ABC transporter periplasmic binding protein YejA 31438868, b2177 ECK120001955 yejB b2178 2274179 2275273 forward putative oligopeptide ABC transporter membrane subunit YejB 31438868, b2178 ECK120001956 yejE b2179 2275273 2276298 forward putative oligopeptide ABC transporter membrane subunit YejE 31438868, b2179 ECK120001957 yejF b2180 2276300 2277889 forward putative oligopeptide ABC transporter ATP binding subunit YejF 31438868, b2180 ECK120001958 yejG b2181 2277893 2278237 reverse protein YejG b2181 ECK125135299 Phantom Gene 2278258 2278498 reverse ECK120001384 bcr b2182 2278570 2279760 reverse multidrug efflux pump Bcr 31438868, b2182 ECK120001960 rsuA b2183 2279788 2280483 reverse 16S rRNA pseudouridine synthase 11694635,11976723,8710514, b2183 ECK120001961 radD b2184 2280632 2282392 forward putative DNA repair helicase RadD 25484163,26774489, b2184 ECK120000876 rplY b2185 2282517 2282801 forward 50S ribosomal subunit protein L25 1092342,1093874,1095766,1100403,1100506,11470155,15339800,1693861,18856069,239743,2444255,2664451,321249,3286550,333392,334534,338605,353489,354931,3888673,3889589,392236,414209,4588880,6159586,6174328,6178424,6181508,6197527,6338479,6340064,6345195,6349628,6349991,6355096,6381990,6401116,6750359,68433,7018905,7019670,7030408,769834,776368,776688,7794529,827440, b2185 ECK120001962 yejK b2186 2282940 2283947 reverse nucleoid-associated protein YejK 21350637, b2186 ECK120001959 yejL b2187 2284129 2284356 forward DUF1414 domain-containing protein YejL 24391520, b2187 ECK120001963 lapC b2188 2284376 2286136 forward lipopolysaccharide signal transducer LapC [EXP-IGI|W|Inferred from genetic interaction] 15489426,32291302,32430473,32788698, Weak b2188 ECK120002509 proL b2189 2286211 2286287 forward tRNA-Pro(GGG) [AS-TAS|W|Traceable author statement] 27288443,7033244, Weak b2189 ECK120003727 b2191 b2191 2288905 2289027 forward ECK120003728 insH8 b2192 2289065 2290045 reverse IS transposase and trans-activator b2192 ECK120001481 narP b2193 2290500 2291147 forward DNA-binding transcriptional dual regulator NarP [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 1482126,15978080,2157156,7699720,8098993,8501030,9302020, Weak b2193 ECK120001965 ccmH b2194 2291358 2292410 reverse holocytochrome synthase CcmH component b2194 ECK120001966 ccmG b2195 2292407 2292964 reverse thiol:disulfide oxidoreductase CcmG b2195 ECK120001967 ccmF b2196 2292961 2294904 reverse holocytochrome synthase CcmF component [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 14532274,24397552,24513106,7635817, Weak b2196 ECK120001968 ccmE b2197 2294901 2295380 reverse periplasmic heme chaperone 12486054,16129669,16364305,19178152,21283867,22121193,24044352, b2197 ECK120002065 ccmD b2198 2295377 2295586 reverse cytochrome maturation protein D 10998170, b2198 ECK120001969 ccmC b2199 2295583 2296320 reverse cytochrome maturation protein C 20599545, b2199 ECK120001970 ccmB b2200 2296362 2297024 reverse cytochrome maturation protein B b2200 ECK120001971 ccmA b2201 2297021 2297644 reverse cytochrome maturation protein A 10708391, b2201 ECK120001972 napC b2202 2297657 2298259 reverse periplasmic nitrate reductase cytochrome c protein b2202 ECK120001973 napB b2203 2298269 2298718 reverse periplasmic nitrate reductase cytochrome c protein b2203 ECK120001974 napH b2204 2298715 2299578 reverse ferredoxin-type protein NapH b2204 ECK120001975 napG b2205 2299565 2300260 reverse ferredoxin-type protein NapG b2205 ECK120001976 napA b2206 2300267 2302753 reverse periplasmic nitrate reductase subunit NapA b2206 ECK120002044 napD b2207 2302750 2303013 reverse NapA signal peptide-binding chaperone NapD [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 10548535,17901208,24314029, Weak b2207 ECK120001977 napF b2208 2303003 2303497 reverse ferredoxin-type protein [EXP-IMP|W|Inferred from mutant phenotype] 10464201,11844760,11967083,12029041,12644479,13129959,16677314,19060147,19361432,20634237,23913318, Weak b2208 ECK120030079 yojO b4604 2303606 2303770 forward uncharacterized protein YojO b4604 ECK120000249 eco b2209 2303905 2304393 forward serine protease inhibitor ecotin 1537814,8508953,9518472,9521759, b2209 ECK120001978 mqo b2210 2305108 2306754 reverse malate:quinone oxidoreductase 10809701,11092847,11566977,15601724, b2210 ECK120001979 yojI b2211 2306972 2308615 reverse ABC transporter family protein / microcin J25 efflux protein 16820466,24891085,30106562,31438868, b2211 ECK120000034 alkB b2212 2308691 2309341 reverse DNA oxidative demethylase 11276424,12862460,15004242,15134932,16153644,16226494,16258838,16793366,18723127,19338370,19786499,19892776,20178806,21048928,2109194,22443471,23773213,24339041,24733044,25043760,25837992,26114961,26237225,26769230,26863410,27015802,28269980,28349464,28371071,28408432,29326044,29803030,29974396,31114894,31847292,32284330,32490196,3283737,33161373,33337498,34586107,3536913,7928996,8582628, b2212 ECK120000026 ada b2213 2309341 2310405 reverse DNA-binding transcriptional dual regulator / DNA repair protein Ada [EXP-IDA|W|Inferred from direct assay],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 11284682,15305584,15305585,16452614,1995192,2002008,2536670,282622,2982792,2987251,29941584,3009022,3047400,3141384,3343221,3526284,3529081,3889845,7896807,7937881,8195077,8676855,8720133,8752326,8755711,9383376,9582376, Strong b2213 ECK120001980 ftp b2214 2310479 2311534 reverse FAD:protein FMN transferase 12876315,15174130,32053772,9274035, b2214 ECK120000663 ompC b2215 2311646 2312749 reverse outer membrane porin C 10096019,10192921,10227163,10347162,10543834,10613880,10906344,12202916,12437978,1328470,1331031,1341988,14633108,1482362,15466019,16077119,16385048,16478504,1696499,17007876,1704313,18438992,18611609,18620846,20086208,20441746,2056524,21339612,2160395,2170338,22562126,22960566,2457014,2464593,2470409,2473775,25086034,2536667,25462331,2559435,28109883,2828311,2846509,28815827,29185080,29518576,2997131,3013884,33004891,3305483,33947759,3531187,3546271,3893556,6086576,6269878,6297988,6302079,6327622,6350261,6366795,6454006,6757670,7033205,7047495,7510255,7934853,8002608,8576061,8603709,8670855,8820656,9218551,9228026,9271205,9422609,9683489,9719640,9738470,9796829, b2215 ECK120002505 micF b4439 2313084 2313176 forward small regulatory RNA MicF [EXP|W|Inferred from experiment],[EXP-IDA|W|Inferred from direct assay] 12069726,17009960,17264113,2193928,2478539,25246476,26774489,30287822,32157864,9478198, Weak b4439 ECK120002250 rcsD b2216 2313488 2316160 forward RcsD phosphotransferase [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 11309126,11758943,12410838,16166540, Weak b2216 ECK120000812 rcsB b2217 2316177 2316827 forward DNA-binding transcriptional activator RcsB [EXP|W|Inferred from experiment] 1482126,1943696,2157156,2404948,32094588,7699720,8098993,8576059, Weak b2217 ECK120000813 rcsC b2218 2317027 2319876 reverse histidine kinase RcsC 11758943,12897016,14514676,15522865,16153174,16427772,19260968,28691662,32094588,8674987,8821933, b2218 ECK120001610 atoS b2219 2320043 2321869 forward sensor histidine kinase AtoS b2219 ECK120001611 atoC b2220 2321866 2323251 forward DNA-binding transcriptional activator/ornithine decarboxylase inhibitor AtoC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 1482126,2157156,2883171,7699720,8098993,8346225, Weak b2220 ECK120001612 atoD b2221 2323447 2324109 forward acetyl-CoA:acetoacetyl-CoA transferase subunit α b2221 ECK120001613 atoA b2222 2324109 2324759 forward acetyl-CoA:acetoacetyl-CoA transferase subunit β b2222 ECK120001614 atoE b2223 2324756 2326078 forward short chain fatty acid transporter b2223 ECK120001615 atoB b2224 2326109 2327293 forward acetyl-CoA acetyltransferase b2224 ECK120003729 yfaP b2225 2327367 2328143 reverse DUF2135 domain-containing protein YfaP b2225 ECK120003730 yfaQ b2226 2328148 2329797 reverse tandem DUF2300 domain-containing protein YfaQ b2226 ECK120003732 yfaS b4500 2329798 2334402 reverse putative macroglobulin family protein, N-terminal fragment b2227,b2228,b4500 ECK120003733 yfaT b2229 2334336 2334959 reverse DUF1175 domain-containing protein YfaT b2229 ECK120001126 yfaA b2230 2334956 2336644 reverse DUF2138 domain-containing protein YfaA b2230 ECK120000416 gyrA b2231 2336793 2339420 reverse DNA gyrase subunit A b2231 ECK120001127 ubiG b2232 2339567 2340289 forward bifunctional 3-demethylubiquinone--methyltransferase and 2-octaprenyl-6-hydroxyphenol methylase 21464517,26251450,5335944, b2232 ECK120002399 yfaL b2233 2340417 2344169 reverse putative autotransporter adhesin YfaL [EXP-IMP|W|Inferred from mutant phenotype] 15659678,20447993,24039985, Weak b2233 ECK120030080 ypaB b4605 2344594 2344737 reverse protein YpaB b4605 ECK120000653 nrdA b2234 2344865 2347150 forward ribonucleoside-diphosphate reductase 1 subunit α b2234 ECK125286415 yoaM b4779 2347350 2347385 reverse protein YoaM b4779 ECK120000654 nrdB b2235 2347384 2348514 forward ribonucleoside-diphosphate reductase 1 subunit β b2235 ECK120002228 yfaE b2236 2348514 2348768 forward ferredoxin-like diferric-tyrosyl radical cofactor maintenance protein YfaE [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 17880186, Weak b2236 ECK120001386 inaA b2237 2348822 2349472 reverse putative lipopolysaccharide kinase InaA 17157494,21723341,22445268,9473030, b2237 ECK120002420 yfaH b2238 2349687 2349893 forward putative uncharacterized protein YfaH b2238 ECK120000392 glpQ b2239 2349935 2351011 reverse glycerophosphoryl diester phosphodiesterase GlpQ 3015871, b2239 ECK120000394 glpT b2240 2351016 2352374 reverse -glycerol 3-phosphate:phosphate antiporter 12813080,12936984,1479338,190005,209011,23959879,3027032,3316209,3329281,363686,374371,4580569,6282417,6290334,6752662,6754693,6773929,770459, b2240 ECK120000384 glpA b2241 2352647 2354275 forward anaerobic glycerol-3-phosphate dehydrogenase subunit A 2403539,3027032,374371,4580569,6282417, b2241 ECK120000385 glpB b2242 2354265 2355524 forward anaerobic glycerol-3-phosphate dehydrogenase subunit B b2242 ECK120000386 glpC b2243 2355521 2356711 forward anaerobic glycerol-3-phosphate dehydrogenase subunit C 12706508,15691972, b2243 ECK120002199 rpnE b2244 2356904 2357803 forward inactive recombination-promoting nuclease-like protein RpnE 30904393, b2244 ECK120026452 ypaA b4543 2357816 2358001 forward protein YpaA b4543 ECK120003734 yfaU b2245 2358042 2358845 reverse 2-keto-3-deoxy-L-rhamnonate aldolase 12454498, b2245 ECK120003735 yfaV b2246 2358863 2360152 reverse putative transporter YfaV 31438868, b2246 ECK120003736 rhmD b2247 2360209 2361414 reverse L-rhamnonate dehydratase b2247 ECK120003737 yfaX b2248 2361429 2362211 reverse putative DNA-binding transcriptional regulator YfaX [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b2248 ECK120003738 yfaY b2249 2362431 2363633 reverse IPR008135 CinA family protein YfaY b2249 ECK120003739 yfaZ b2250 2363733 2364275 reverse putative porin YfaZ 15215418, b2250 ECK120003740 nudI b2251 2364554 2364979 forward pyrimidine deoxynucleotide diphosphatase NudI 29551348, b2251 ECK120003741 ais b2252 2365018 2365620 reverse putative lipopolysaccharide core heptose(II)-phosphate phosphatase b2252 ECK120003742 arnB b2253 2365910 2367067 forward UDP-4-amino-4-deoxy-L-arabinose aminotransferase b2253 ECK120003743 arnC b2254 2367071 2368039 forward undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase b2254 ECK120003744 arnA b2255 2368039 2370021 forward fused UDP-4-amino-4-deoxy-L-arabinose formyltransferase/UDP-glucuronate dehydrogenase 10373459,21602383,23852738,26696268, b2255 ECK120003745 arnD b2256 2370018 2370908 forward putative 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD [AS-HYPO|W|Author hypothesis] 10373459,11222580,11535605,15659161,15695810,7565089, Weak b2256 ECK120003746 arnT b2257 2370908 2372560 forward lipid IV 4-amino-4-deoxy-L-arabinosyltransferase 10373459,11222580,15659161,7565089, b2257 ECK120016312 arnE b4544 2372557 2372892 forward undecaprenyl-phosphate-α-L-Ara4N flippase - ArnE subunit b4544 ECK120003747 arnF b2258 2372892 2373278 forward undecaprenyl-phosphate-α-L-Ara4N flippase - ArnF subunit b2258 ECK120003748 pmrD b2259 2373272 2373538 reverse signal transduction protein PmrD 20384697,25480013, b2259 ECK120002291 menE b2260 2373648 2375003 reverse -succinylbenzoate—CoA ligase 18762421, b2260 ECK120001486 menC b2261 2375000 2375962 reverse -succinylbenzoate synthase b2261 ECK120001336 menB b2262 2375962 2376819 reverse 1,4-dihydroxy-2-naphthoyl-CoA synthase b2262 ECK120002292 menH b2263 2376834 2377592 reverse 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase b2263 ECK120000572 menD b2264 2377589 2379259 reverse 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase b2264 ECK120002230 menF b2265 2379348 2380643 reverse isochorismate synthase MenF b2265 ECK120003749 elaB b2266 2380722 2381027 reverse tail-anchored inner membrane protein ElaB 34644400, b2266 ECK120003750 elaA b2267 2381082 2381543 reverse putative acetyltransferase ElaA b2267 ECK120003751 rbn b2268 2381608 2382525 forward ribonuclease BN b2268 ECK120003752 elaD b2269 2382713 2383924 forward protease ElaD b2269 ECK120003753 yfbK b2270 2383995 2385722 reverse IPR002035/DUF3520 domain-containing protein YfbK 32053772, b2270 ECK120003754 yfbL b2271 2385860 2386831 forward putative peptidase YfbL b2271 ECK120003755 yfbM b2272 2386934 2387437 forward DUF1877 domain-containing protein YfbM b2272 ECK120003756 yfbN b2273 2387710 2388426 reverse uncharacterized protein YfbN b2273 ECK120003757 yfbO b2274 2388635 2389057 forward uncharacterized protein YfbO b2274 ECK120003758 yfbP b2275 2389116 2389964 forward uncharacterized protein YfbP b2275 ECK120001998 nuoN b2276 2390048 2391505 reverse NADH:quinone oxidoreductase subunit N 20509166, b2276 ECK120001707 nuoM b2277 2391512 2393041 reverse NADH:quinone oxidoreductase subunit M 24325249,26134569, b2277 ECK120001997 nuoL b2278 2393205 2395046 reverse NADH:quinone oxidoreductase subunit L 20509166,24778264,26147723,27391676, b2278 ECK120001996 nuoK b2279 2395043 2395345 reverse NADH:quinone oxidoreductase subunit K b2279 ECK120001995 nuoJ b2280 2395342 2395896 reverse NADH:quinone oxidoreductase subunit J b2280 ECK120001994 nuoI b2281 2395908 2396450 reverse NADH:quinone oxidoreductase subunit I 21562562, b2281 ECK120001993 nuoH b2282 2396465 2397442 reverse NADH:quinone oxidoreductase subunit H 20509166,21924889,25545070,27449624,28553265, b2282 ECK120001992 nuoG b2283 2397439 2400165 reverse NADH:quinone oxidoreductase subunit G b2283 ECK120001708 nuoF b2284 2400218 2401555 reverse NADH:quinone oxidoreductase subunit F 31186428, b2284 ECK120001991 nuoE b2285 2401552 2402052 reverse NADH:quinone oxidoreductase subunit E 20959113,23543743,28821859, b2285 ECK120001990 nuoC b2286 2402055 2403845 reverse NADH:quinone oxidoreductase subunit CD 19348883,24325249,28553265, b2286 ECK120001989 nuoB b2287 2403951 2404613 reverse NADH:quinone oxidoreductase subunit B 28553265, b2287 ECK120001988 nuoA b2288 2404629 2405072 reverse NADH:quinone oxidoreductase subunit A b2288 ECK120002026 lrhA b2289 2405703 2406641 reverse DNA-binding transcriptional dual regulator LrhA [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 12123461,7565112,9882671, Weak b2289 ECK120003759 alaA b2290 2407561 2408778 forward glutamate—pyruvate aminotransferase AlaA b2290 ECK120003760 yfbR b2291 2408862 2409461 forward dCMP phosphohydrolase b2291 ECK120003761 yfbS b2292 2409520 2411352 reverse putative transporter YfbS 24391520,31438868, b2292 ECK120003762 hxpA b2293 2411439 2412089 reverse hexitol phosphatase A b2293 ECK120003763 yfbU b2294 2412100 2412594 reverse PF03887 family protein YfbU b2294 ECK120003764 yfbV b2295 2412677 2413132 reverse PF04217 family membrane protein YfbV b2295 ECK120000024 ackA b2296 2413470 2414672 forward acetate kinase 2536666, b2296 ECK120002445 pta b2297 2414747 2416891 forward phosphate acetyltransferase 10486127,2661531,7033467, b2297 ECK120003765 yfcC b2298 2417081 2418601 forward putative transporter YfcC 25739269,31438868, b2298 ECK120003766 yfcD b2299 2418634 2419176 reverse putative Nudix hydrolase YfcD b2299 ECK120003767 yfcE b2300 2419234 2419788 reverse phosphodiesterase YfcE b2300 ECK120003768 yfcF b2301 2419841 2420485 reverse glutathione -transferase YfcF b2301 ECK120003769 yfcG b2302 2420621 2421268 forward disulfide bond oxidoreductase YfcG b2302 ECK120003770 folX b2303 2421325 2421687 forward dihydroneopterin triphosphate 2'-epimerase b2303 ECK120003771 yfcH b2304 2421708 2422601 forward epimerase family protein YfcH b2304 ECK120003772 rpnB b2305 2422649 2423539 reverse recombination-promoting nuclease RpnB [EXP-IMP|W|Inferred from mutant phenotype] 28096446, Weak b2305 ECK120000445 hisP b2306 2423736 2424509 reverse lysine/arginine/ornithine ABC transporter / histidine ABC transporter, ATP binding subunit b2306 ECK120000006 hisM b2307 2424517 2425233 reverse lysine/arginine/ornithine ABC transporter / histidine ABC transporter, membrane subunit HisM b2307 ECK120002028 hisQ b2308 2425230 2425916 reverse lysine/arginine/ornithine ABC transporter / histidine ABC transporter, membrane subunit HisQ b2308 ECK120002027 hisJ b2309 2426006 2426788 reverse histidine ABC transporter periplasmic binding protein 19921465,24036119, b2309 ECK120000068 argT b2310 2427009 2427791 reverse lysine/arginine/ornithine ABC transporter periplasmic binding protein b2310 ECK120001033 ubiX b2311 2428057 2428626 reverse flavin prenyltransferase 3040734, b2311 ECK120000785 purF b2312 2428721 2430238 reverse amidophosphoribosyltransferase 2991286,3047685,3058703,6277938, b2312 ECK120000165 cvpA b2313 2430275 2430763 reverse colicin V production protein [EXP-IMP|W|Inferred from mutant phenotype] 2542219, Weak b2313 ECK120000212 dedD b2314 2431022 2431684 reverse cell division protein DedD [EXP-IMP|W|Inferred from mutant phenotype] 19684127, Weak b2314 ECK120000321 folC b2315 2431674 2432942 reverse bifunctional folylpolyglutamate synthetase / dihydrofolate synthetase 3040739, b2315 ECK120000211 accD b2316 2433012 2433926 reverse acetyl-CoA carboxyltransferase subunit β 1886618, b2316 ECK120000210 dedA b2317 2434082 2434741 reverse DedA family protein DedA b2317 ECK120000447 truA b2318 2434824 2435636 reverse tRNA pseudouridine synthase 12756333,1657874,21142053,2407715,27535647,3040734,3112412,34783647,350834,355232,6805514, b2318 ECK120001048 usg b2319 2435636 2436649 reverse putative semialdehyde dehydrogenase Usg b2319 ECK120002648 pdxB b2320 2436715 2437851 reverse erythronate-4-phosphate dehydrogenase b2320 ECK120000223 flk b2321 2437950 2438945 forward putative flagella assembly protein b2321 ECK120003773 yfcJ b2322 2438942 2440120 reverse putative transporter YfcJ 31438868, b2322 ECK120000268 fabB b2323 2440385 2441605 reverse 3-oxoacyl-[acyl carrier protein] synthase 1 b2323 ECK120003774 mnmC b2324 2441764 2443770 forward fused tRNA 5-aminomethyl-2-thiouridylate methyltransferase and tRNA 5-aminomethyl-2-thiouridylate synthase 31013547,342494, b2324 ECK120003775 yfcL b2325 2443891 2444169 reverse PF08891 family protein YfcL b2325 ECK120003776 epmC b2326 2444203 2444751 reverse EF-P-Lys34 hydroxylase b2326 ECK120001128 yfcA b2327 2444751 2445560 reverse putative transporter YfcA b2327 ECK120000573 mepA b2328 2445560 2446384 reverse peptidoglycan DD-endopeptidase/peptidoglycan LD-endopeptidase b2328 ECK120000071 aroC b2329 2446388 2447473 reverse chorismate synthase b2329 ECK120002301 prmB b2330 2447508 2448440 reverse ribosomal protein L3 -glutamine methyltransferase b2330 ECK120003777 smrB b2331 2448606 2449157 forward putative endonuclease SmrB b2331 ECK120003778 yfcO b2332 2449228 2450049 reverse DUF2544 domain-containing protein YfcO [COMP-AINF|W|Inferred computationally without human oversight] 12192075,21344461,23382825, Weak b2332 ECK120003779 yfcP b2333 2450051 2450590 reverse putative fimbrial protein YfcP [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825, Weak b2333 ECK120003780 yfcQ b2334 2450587 2451075 reverse putative fimbrial protein YfcQ [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825, Weak b2334 ECK120003781 yfcR b2335 2451072 2451584 reverse putative fimbrial protein YfcR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825,24391520, Weak b2335 ECK120003782 yfcS b2336 2451584 2452336 reverse putative fimbrial chaperone YfcS [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 12192075,20345943,21344461,23382825, Weak b2336 ECK120003784 yfcU b4661 2452356 2455001 reverse putative outer membrane usher protein YfcU 10496884,11014799,21344461,23382825, b2337,b2338,b4661 ECK120003785 yfcV b2339 2455083 2455646 reverse putative fimbrial protein YfcV [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825, Weak b2339 ECK120003786 sixA b2340 2456327 2456812 reverse phosphohistidine phosphatase SixA 10192921,10734219, b2340 ECK120003787 fadJ b2341 2457015 2459159 reverse 3-hydroxyacyl-CoA dehydrogenase FadJ 12270828,12949091,22248859, b2341 ECK120003788 fadI b2342 2459159 2460469 reverse 3-ketoacyl-CoA thiolase FadI b2342 ECK120003789 yfcZ b2343 2460650 2460934 reverse DUF406 domain-containing protein YfcZ b2343 ECK120000274 fadL b2344 2461306 2462646 forward long-chain fatty acid outer membrane channel / bacteriophage T2 receptor [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[EXP-IMP|W|Inferred from mutant phenotype] 10328825,18641391,29518576,3001045,3286621,3536849,383713,3881440,6376508, Strong b2344 ECK120003790 yfdF b2345 2463012 2464070 forward protein YfdF b2345 ECK120003791 mlaA b2346 2464252 2465007 reverse intermembrane phospholipid transport system - outer membrane lipoprotein MlaA 18304323,29038444,32053772,32955879,34716276, b2346 ECK120003792 yfdC b2347 2465301 2466233 forward inner membrane protein YfdC 31438868, b2347 ECK120002459 argW b2348 2466309 2466383 forward tRNA-Arg(CCU) [AS-TAS|W|Traceable author statement] 7033244, Weak b2348 ECK120003793 intS b2349 2466545 2467702 forward CPS-53 (KpLE1) prophage; prophage CPS-53 integrase [EXP-IMP|W|Inferred from mutant phenotype] 17545146, Weak b2349 ECK120003794 yfdG b2350 2467855 2468217 forward CPS-53 (KpLE1) prophage; putative bactoprenol-linked glucose translocase 11283281, b2350 ECK120003795 yfdH b2351 2468214 2469134 forward CPS-53 (KpLE1) prophage; bactoprenol glucosyl transferase 11283281, b2351 ECK120003796 yfdI b2352 2469131 2470462 forward CPS-53 (KpLE1) prophage; serotype-specific glucosyl transferase YfdI 11283281, b2352 ECK125229288 ryeG 2470472 2470665 reverse small RNA RyeG [EXP-IMP|W|Inferred from mutant phenotype] 20683441,26469694, Weak ECK125286390 yodE b4780 2470497 2470643 reverse CPS-53 (KpLE1) prophage; toxic protein YodE [EXP-IMP|W|Inferred from mutant phenotype] 32813020, Weak b4780 ECK120003797 tfaS b2353 2470803 2471105 forward b2353 ECK120003798 yfdK b2354 2471077 2471517 reverse CPS-53 (KpLE1) prophage; putative tail fiber assembly protein YfdK b2354 ECK120003799 yfdL b2355 2471544 2472062 reverse CPS-53 (KpLE1) prophage; putative uncharacterized protein YfdL b2355 ECK120003800 yfdM b2356 2472112 2472387 reverse CPS-53 (KpLE1) prophage; putative methyltransferase YfdM b2356 ECK120003801 yfdN b2357 2472387 2472881 reverse CPS-53 (KpLE1) prophage; uncharacterized protein YfdN b2357 ECK120003802 yfdO b2358 2472878 2473246 reverse CPS-53 (KpLE1) prophage; protein YdfO b2358 ECK120003803 yfdP b2359 2473604 2473966 forward CPS-53 (KpLE1) prophage; uncharacterized protein YfdP b2359 ECK120003804 yfdQ b2360 2474032 2474856 forward CPS-53 (KpLE1) prophage; DUF2303 domain-containing protein YfdQ 23228329, b2360 ECK120003805 yfdR b2361 2474984 2475520 forward CPS-53 (KpLE1) prophage; 5'-deoxynucleotidase b2361 ECK120003806 yfdS b2362 2475511 2475873 forward CPS-53 (KpLE1) prophage; protein YfdS b2362 ECK120003807 yfdT b2363 2475873 2476178 forward CPS-53 (KpLE1) prophage; protein YfdT b2363 ECK120016313 ypdJ b4545 2476094 2476234 forward CPS-53 (KpLE1) prophage; putative uncharacterized protein YpdJ b4545 ECK120002665 torI b4501 2476310 2476510 forward CPS-53 (KpLE1) prophage; prophage CPS-53 recombination directionality factor and response regulator inhibitor [EXP-IMP|W|Inferred from mutant phenotype] 15197250, Weak b4501 ECK125240967 pawZ b4643 2476584 2476598 forward b4643 ECK120002429 dsdC b2364 2476694 2477629 reverse DNA-binding transcriptional dual regulator DsdC 6296057,7592420, b2364 ECK120000244 dsdX b2365 2477847 2479184 forward D-serine transporter b2365 ECK120000243 dsdA b2366 2479202 2480530 forward D-serine ammonia-lyase 1090587,1095577,1099073,2069576,4921210,5340178,6246062,6343359,6998484,7019208,770418,9222324, b2366 ECK120002436 emrY b2367 2480638 2482176 reverse tripartite efflux pump membrane subunit EmrY b2367 ECK120003808 emrK b2368 2482176 2483339 reverse tripartite efflux pump membrane fusion protein EmrK b2368 ECK125286400 evgL b4781 2483729 2483758 forward protein EvgL b4781 ECK120001557 evgA b2369 2483755 2484369 forward DNA-binding transcriptional activator EvgA b2369 ECK120001558 evgS b2370 2484374 2487967 forward sensor histidine kinase EvgS b2370 ECK120003809 yfdE b2371 2488023 2489168 reverse acetyl-CoA:oxalate CoA-transferase b2371 ECK120003810 yfdV b2372 2489242 2490186 reverse putative transport protein YfdV [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 11574054,16397293, Weak b2372 ECK120003811 oxc b2373 2490256 2491950 reverse oxalyl-CoA decarboxylase b2373 ECK120003812 frc b2374 2492004 2493254 reverse formyl-CoA transferase b2374 ECK120003813 yfdX b2375 2493767 2494402 reverse protein YfdX 24391520, b2375 ECK120003814 ypdI b2376 2494698 2494973 forward colanic acid synthesis putative lipoprotein YpdI [EXP-IMP|W|Inferred from mutant phenotype] 15183873,32053772, Weak b2376 ECK120003815 yfdY b2377 2495050 2495292 reverse DUF2545 domain-containing protein YfdY b2377 ECK120003816 lpxP b2378 2495645 2496565 forward palmitoleoyl acyltransferase 21106097, b2378 ECK120002617 tpke70 2496194 2496629 reverse ECK120048859 ypdK b4680 2496921 2496992 forward uncharacterized membrane protein YpdK b4680 ECK120003817 alaC b2379 2497057 2498295 reverse glutamate—pyruvate aminotransferase AlaC b2379 ECK120003818 pyrS b2380 2498671 2500368 forward sensor histidine kinase PyrS 11361063,11514505,12366850, b2380 ECK120003819 pyrR b2381 2500383 2501117 forward DNA-binding transcriptional activator PyrR 11361063, b2381 ECK120003820 ypdC b2382 2501130 2501987 forward putative AraC-type DNA-binding transcriptional regulator YpdC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 10734204,15556475,23222720, Weak b2382 ECK120003821 fryA b2383 2501990 2504485 reverse putative PTS multiphosphoryl transfer protein FryA 31438868, b2383 ECK120003822 ypdE b2384 2504510 2505547 reverse aminopeptidase YpdE b2384 ECK120003823 ypdF b2385 2505547 2506632 reverse aminopeptidase YpdF b2385 ECK120003824 fryC b2386 2506647 2507894 reverse putative PTS enzyme IIC component FryC 31438868, b2386 ECK120003825 fryB b2387 2507916 2508242 reverse putative PTS enzyme IIB component FryB 31438868, b2387 ECK120002426 glk b2388 2508461 2509426 reverse glucokinase 12889033,14231443,6313627, b2388 ECK120003826 yfeO b2389 2509630 2510886 forward putative transport protein YfeO 32954454, b2389 ECK120003827 ypeC b2390 2511001 2511327 forward DUF2502 domain-containing protein YpeC b2390 ECK120003828 mntH b2392 2511468 2512706 reverse Mn symporter MntH 11466284, b2392 ECK125303712 ypeD b4819 2512687 2512776 reverse protein YpeD b4819 ECK120001896 nupC b2393 2513042 2514244 forward nucleoside:H symporter NupC 1512211,28385889,29545094,32994326,4591127, b2393 ECK120003829 insL3 b2394 2514331 2515443 forward putative IS186/IS421 transposase b2394 ECK120001129 pdeA b2395 2515643 2517832 reverse putative c-di-GMP phosphodiesterase PdeA b2395 ECK120002455 alaX b2396 2518041 2518116 reverse tRNA-Ala(GGC) [AS-TAS|W|Traceable author statement] 7033244, Weak b2396 ECK120002454 alaW b2397 2518156 2518231 reverse tRNA-Ala(GGC) [AS-TAS|W|Traceable author statement] 7033244, Weak b2397 ECK120001395 yfeC b2398 2518467 2518811 forward DNA-binding transcriptional dual regulator YfeC [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15556475, Weak b2398 ECK120001396 yfeD b2399 2518813 2519205 forward putative DNA-binding transcriptional regulator YfeD [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 10734204,15556475, Weak b2399 ECK120000400 gltX b2400 2519257 2520672 reverse glutamate—tRNA ligase 19684138,25005090,25686371,25860020,3015933, b2400 ECK120002552 valU b2401 2520931 2521006 forward tRNA-Val(UAC) [AS-TAS|W|Traceable author statement] 7033244, Weak b2401 ECK120002555 valX b2402 2521051 2521126 forward tRNA-Val(UAC) [AS-TAS|W|Traceable author statement] 7033244, Weak b2402 ECK120002556 valY b2403 2521173 2521248 forward tRNA-Val(UAC) [AS-TAS|W|Traceable author statement] 7033244, Weak b2403 ECK120002498 lysV b2404 2521253 2521328 forward tRNA-Lys(UUU) [AS-TAS|W|Traceable author statement] 15558052,7033244, Weak b2404 ECK120001130 xapR b2405 2521593 2522477 reverse DNA-binding transcriptional activator XapR b2405 ECK120002428 xapB b2406 2522729 2523985 reverse xanthosine:H symporter XapB 11466294, b2406 ECK120004462 xapA b2407 2524045 2524878 reverse xanthosine phosphorylase b2407 ECK120003830 yfeN b2408 2525127 2525891 forward putative outer membrane porin YfeN b2408 ECK120003831 yfeR b2409 2525930 2526856 reverse putative DNA-binding transcriptional regulator YfeR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b2409 ECK120002244 yfeH b2410 2526946 2527944 forward putative solute:Na symporter 31438868, b2410 ECK120016314 ypeB b4546 2527941 2528159 reverse PF12843 family protein YpeB b4546 ECK120000527 ligA b2411 2528161 2530176 reverse DNA ligase 28223499,30617079,4306814,4306816, b2411 ECK120003832 zipA b2412 2530247 2531233 reverse cell division protein ZipA [EXP-IMP|W|Inferred from mutant phenotype] 19669505,22198391,22329688,29061666,9008158, Weak b2412 ECK120000003 cysZ b2413 2531463 2532224 forward sulfate:H symporter 29792261,6341507, b2413 ECK120000187 cysK b2414 2532409 2533380 forward cysteine synthase A b2414 ECK120000779 ptsH b2415 2533764 2534021 forward phosphocarrier protein HPr [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 1483471,17449611,26285685,29229699,29868643,30729074,4942330,5545082,8226757,8576048,9334229,9868784, Weak b2415 ECK120000780 ptsI b2416 2534066 2535793 forward PTS enzyme I b2416 ECK120000161 crr b2417 2535834 2536343 forward Enzyme IIA 11060015,1606145,16439362,1911770,1961703,2411636,26285685,30729074,31438868,6099314,8518729, b2417 ECK120003833 pdxK b2418 2536386 2537237 reverse pyridoxine/pyridoxal/pyridoxamine kinase 11700988,33860878,6250600,6270288,6289642,8595869, b2418 ECK120003834 yfeK b2419 2537342 2537716 forward DUF5329 domain-containing protein YfeK b2419 ECK120003835 yfeS b2420 2537749 2538483 forward PF05406 family protein YfeS b2420 ECK120000188 cysM b2421 2538672 2539583 reverse cysteine synthase B 22607201,30547566,31617110,7988897, b2421 ECK120000178 cysA b2422 2539717 2540814 reverse sulfate/thiosulfate ABC transporter ATP binding subunit b2422 ECK120000193 cysW b2423 2540804 2541679 reverse sulfate/thiosulfate ABC transporter inner membrane subunit CysW b2423 ECK120000192 cysU b2424 2541679 2542512 reverse sulfate/thiosulfate ABC transporter inner membrane subunit CysU b2424 ECK120000190 cysP b2425 2542512 2543528 reverse thiosulfate/sulfate ABC transporter periplasmic binding protein CysP b2425 ECK120002035 ucpA b2426 2543832 2544623 reverse oxidoreductase UcpA b2426 ECK120003836 murR b2427 2544752 2545609 reverse DNA-binding transcriptional dual regulator MurR b2427 ECK120003837 murQ b2428 2545773 2546669 forward -acetylmuramic acid 6-phosphate etherase 18723630, b2428 ECK120003838 murP b2429 2546673 2548097 forward N-acetylmuramic acid-specific PTS enzyme IICB component / anhydro-N-acetylmuramic acid transporter 15060041, b2429 ECK120003839 yfeW b2430 2548102 2549406 forward penicillin binding protein 4B [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 16402224,32053772, Strong b2430 ECK120003840 yfeX b2431 2549646 2550545 reverse porphyrinogen peroxidase 29769716, b2431 ECK120003841 yfeY b2432 2550641 2551216 reverse DUF1131 domain-containing lipoprotein YfeY b2432 ECK120003842 yfeZ b2433 2551277 2551726 reverse putative inner membrane protein b2433 ECK120003843 ypeA b2434 2551713 2552138 reverse putative acetyltransferase YpeA b2434 ECK120001755 amiA b2435 2552352 2553221 forward -acetylmuramoyl-L-alanine amidase A 1102308,12399477,18390656,21764913,6133749, b2435 ECK120002078 hemF b2436 2553225 2554124 forward coproporphyrinogen III oxidase b2436 ECK120002079 eutR b2437 2554130 2555182 reverse putative DNA-binding transcriptional regulator EutR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b2437 ECK120003844 eutK b2438 2555228 2555728 reverse putative structural protein, ethanolamine utilization microcompartment [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 20044574,27718375, Weak b2438 ECK120003845 eutL b2439 2555741 2556400 reverse putative structural protein, ethanolamine utilization microcompartment b2439 ECK120002566 eutC b2440 2556410 2557297 reverse ethanolamine ammonia-lyase subunit β b2440 ECK120002565 eutB b2441 2557318 2558679 reverse ethanolamine ammonia-lyase subunit α b2441 ECK120003846 intZ b2442 2558858 2560066 forward CPZ-55 prophage; putative phage integrase IntZ b2442 ECK120003847 yffL b2443 2560257 2560898 forward CPZ-55 prophage; uncharacterized protein YffL b2443 ECK120003848 yffM b2444 2561368 2561613 forward CPZ-55 prophage; uncharacterized protein YffM b2444 ECK120003849 yffN b2445 2561625 2561993 forward CPZ-55 prophage; uncharacterized protein YffN b2445 ECK120003850 yffO b2446 2562111 2562527 forward CPZ-55 prophage; uncharacterized protein YffO b2446 ECK120003851 yffP b2447 2562524 2563117 forward CPZ-55 prophage; uncharacterized protein YffP b2447 ECK120003852 yffQ b2448 2563592 2563969 forward CPZ-55 prophage; uncharacterized protein YffQ b2448 ECK120003853 yffR b2449 2563980 2564372 forward CPZ-55 prophage; uncharacterized protein YffR b2449 ECK120003854 yffS b2450 2564523 2565332 forward CPZ-55 prophage; uncharacterized protein YffS b2450 ECK120003855 eutA b2451 2565481 2566884 reverse ethanolamine ammonia-lyase reactivase EutA [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 15466038, Weak b2451 ECK120003856 eutH b2452 2566881 2568107 reverse putative ethanolamine permease EutH [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10464203, Weak b2452 ECK120003857 eutG b2453 2568324 2569511 reverse putative alcohol dehydrogenase EutG b2453 ECK120003858 eutJ b2454 2569501 2570337 reverse putative ethanolamine utilization chaperonin EutJ b2454 ECK120003859 eutE b2455 2570348 2571751 reverse acetaldehyde dehydrogenase (acetylating) EutE 22731523,29188185,30359264, b2455 ECK120003860 eutN b2456 2571763 2572050 reverse putative ethanolamine catabolic microcompartment shell protein EutN b2456 ECK120003861 eutM b2457 2572157 2572450 reverse putative ethanolamine catabolic microcompartment shell protein EutM b2457 ECK120003862 eutD b2458 2572489 2573505 reverse phosphate acetyltransferase EutD b2458 ECK120003863 eutT b2459 2573502 2574305 reverse putative ethanolamine utilization cobalamin adenosyltransferase b2459 ECK120003864 eutQ b2460 2574302 2575003 reverse putative ethanolamine utilization acetate kinase EutQ b2460 ECK120003865 eutP b2461 2574978 2575457 reverse putative ethanolamine utilization acetate kinase EutP b2461 ECK120003866 eutS b2462 2575470 2575805 reverse putative ethanolamine catabolic microcompartment shell protein EutS b2462 ECK120003867 maeB b2463 2576098 2578377 reverse malate dehydrogenase (oxaloacetate-decarboxylating) (NADP) b2463 ECK120001731 talA b2464 2578666 2579616 forward transaldolase A 11325924,17046540,19695296, b2464 ECK120002005 tktB b2465 2579636 2581639 forward transketolase 2 23046715,23850830,32046235, b2465 ECK120003868 ypfG b2466 2581734 2582777 reverse DUF1176 domain-containing protein YpfG b2466 ECK120002271 nudK b2467 2582903 2583478 reverse GDP-mannose hydrolase b2467 ECK120002270 aegA b2468 2583546 2585525 reverse putative oxidoreductase AegA [COMP-HINF|W|Inferred by a human based on computational evidence],[EXP-IGI|W|Inferred from genetic interaction] 30803968,30885932,8955321, Weak b2468 ECK120001423 narQ b2469 2585731 2587431 forward sensor histidine kinase NarQ b2469 ECK120000012 acrD b2470 2587595 2590708 forward multidrug efflux pump RND permease AcrD 16166532,16428427,18157731,27050393,27105118,31251753,31438868, b2470 ECK120002599 ypfM b4606 2590807 2590866 reverse uncharacterized protein YpfM b4606 ECK120001131 yffB b2471 2591247 2591603 forward putative reductase YffB b2471 ECK120000202 dapE b2472 2591607 2592734 forward succinyl-diaminopimelate desuccinylase 13756049,1644752, b2472 ECK120016315 ypfN b4547 2592762 2592962 forward PF13980 family protein YpfN b4547 ECK120003869 ypfH b2473 2593072 2593770 reverse esterase YpfH [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 15808744, Weak b2473 ECK120003870 tmcA b2474 2593844 2595859 reverse tRNA cytidine acetyltransferase b2474 ECK120003871 ypfJ b2475 2595874 2596737 reverse uncharacterized protein YpfJ b2475 ECK120000782 purC b2476 2596905 2597618 reverse phosphoribosylaminoimidazole-succinocarboxamide synthase 2120198,6365889, b2476 ECK120000651 bamC b2477 2597831 2598865 reverse outer membrane protein assembly factor BamC [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IPI|W|Inferred from physical interaction],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 15851030,20378773,26900875,32053772, Strong b2477 ECK120000199 dapA b2478 2598882 2599760 reverse 4-hydroxy-tetrahydrodipicolinate synthase 4967862, b2478 ECK120001132 gcvR b2479 2599906 2600478 forward putative transcriptional regulator GcvR 9537378, b2479 ECK120000104 bcp b2480 2600478 2600948 forward thiol peroxidase b2480 ECK120001133 hyfA b2481 2601201 2601818 forward hydrogenase 4 component A 9387241, b2481 ECK120001255 hyfB b2482 2601818 2603836 forward hydrogenase 4 component B 9387241, b2482 ECK120003872 hyfC b2483 2603847 2604794 forward hydrogenase 4 component C b2483 ECK120003873 hyfD b2484 2604811 2606250 forward hydrogenase 4 component D 9387241, b2484 ECK120003874 hyfE b2485 2606262 2606912 forward hydrogenase 4 component E b2485 ECK120003875 hyfF b2486 2606917 2608497 forward hydrogenase 4 component F b2486 ECK120003876 hyfG b2487 2608487 2610154 forward hydrogenase 4 catalytic subunit HyfG 22771922,9387241, b2487 ECK120003877 hyfH b2488 2610164 2610709 forward hydrogenase 4 component H 9387241, b2488 ECK120003878 hyfI b2489 2610706 2611464 forward hydrogenase 4 catalytic subunit HyfI 9387241, b2489 ECK120003879 hyfJ b2490 2611457 2611870 forward putative hydrogenase 4 assembly protein [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 9387241, Weak b2490 ECK120003880 hyfR b2491 2611900 2613912 forward DNA-binding transcriptional activator HyfR [EXP|W|Inferred from experiment] 9387241, Weak b2491 ECK120003881 focB b2492 2613934 2614782 forward formate channel FocB 28738779,9387241, b2492 ECK120003882 yfgO b2493 2614820 2615881 reverse putative transporter YfgO 31438868, b2493 ECK120003883 bepA b2494 2616094 2617557 forward β-barrel assembly-enhancing protease [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 20487295,24003122,24391520,27732863, Strong b2494 ECK120003884 yfgD b2495 2617578 2617937 forward putative oxidoreductase YfgD b2495 ECK120003885 hda b2496 2618075 2618776 reverse inibitor of reinitiation of DNA replication [EXP-IDA|W|Inferred from direct assay] 11483528,15189445,16855240,19432804, Weak b2496 ECK120002031 uraA b2497 2618871 2620160 reverse uracil:H symporter UraA b2497 ECK120001303 upp b2498 2620246 2620872 reverse uracil phosphoribosyltransferase 11114920,1371255,18535147, b2498 ECK120000789 purM b2499 2621197 2622234 forward phosphoribosylformylglycinamide cyclo-ligase 3015935, b2499 ECK120000790 purN b2500 2622234 2622872 forward phosphoribosylglycinamide formyltransferase 1 11604543,1371255,2644189,3301838, b2500 ECK120001466 ppk b2501 2623044 2625110 forward polyphosphate kinase b2501 ECK120001369 ppx b2502 2625115 2626656 forward exopolyphosphatase 10099396,10441348,16204477,24645672,25192989,8212131,9472324, b2502 ECK120003886 pdeF b2503 2626695 2628938 reverse cyclic di-GMP phosphodiesterase PdeF b2503 ECK120003887 yfgG b2504 2629290 2629481 forward nickel/cobalt stress response protein YfgG 29769716, b2504 ECK120003888 yfgH b2505 2629792 2630310 forward lipoprotein YfgH 32053772, b2505 ECK120003889 yfgI b2506 2630326 2630865 forward nalidixic acid resistance protein YfgI [EXP-IMP|W|Inferred from mutant phenotype] 23308060, Weak b2506 ECK120000413 guaA b2507 2630958 2632535 reverse GMP synthetase b2507 ECK120000414 guaB b2508 2632604 2634070 reverse inosine 5'-monophosphate dehydrogenase b2508 ECK120001061 xseA b2509 2634232 2635602 forward exodeoxyribonuclease VII subunit XseA b2509 ECK120003890 yfgJ b2510 2635599 2635814 reverse zinc ribbon domain-containing protein YfgJ b2510 ECK120003891 der b2511 2635884 2637356 reverse 50S ribosomal subunit stability factor [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 11387344,11976298,16930151,20026263,22750478,25879934,27979707, Weak b2511 ECK120003892 bamB b2512 2637474 2638652 reverse outer membrane protein assembly factor BamB [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 15851030,20378773,26900875,31113901,32053772, Strong b2512 ECK120003893 yfgM b2513 2638663 2639283 reverse ancillary SecYEG translocon subunit [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host],[EXP-IGI|W|Inferred from genetic interaction] 21210718,24855643,25403562,31699901,33531386, Strong b2513 ECK120000446 hisS b2514 2639301 2640575 reverse histidine—tRNA ligase 28288813, b2514 ECK120002645 sroE b4761 2640595 2640686 reverse small RNA SroE 11553332, b4761 ECK120000363 ispG b2515 2640686 2641804 reverse ()-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) 11717301,12076162,19919056,22586085,23133596, b2515 ECK120000013 rodZ b2516 2641831 2642844 reverse cytoskeleton protein RodZ [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 17014715,19008860,19078962,19164570,20528937,27477251,29480545, Weak b2516 ECK120002263 rlmN b2517 2643129 2644283 reverse 23S rRNA mA37 methyltransferase 23034227,23752511,26253978,28643349,30308313,34085241, b2517 ECK120000643 ndk b2518 2644433 2644864 reverse nucleoside diphosphate kinase b2518 ECK120003894 pbpC b2519 2645013 2647325 reverse peptidoglycan glycosyltransferase PbpC 10383966,15757509,15761956,18165305,9449253, b2519 ECK120003895 yfhM b2520 2647326 2652287 reverse α-macroglobulin [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 15186489,18697741,26100869,32053772, Strong b2520 ECK120001548 sseA b2521 2652494 2653339 forward 3-mercaptopyruvate sulfurtransferase 20406421, b2521 ECK125302578 timR b4811 2653356 2653455 reverse putative small regulatory RNA TimR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 33172998, Weak b4811 ECK120002618 C0614 2653452 2653538 reverse ECK120002619 IS128 2653515 2653723 forward ECK120002590 ryfA b4440 2653855 2654158 forward small regulatory RNA RyfA [EXP-IMP|W|Inferred from mutant phenotype] 10673004,26469694, Weak b4440 ECK125302579 timP b4812 2654001 2654126 forward putative toxic protein TimP [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 33172998, Weak b4812 ECK120001549 sseB b2522 2654157 2654933 reverse protein SseB [EXP-IMP|W|Inferred from mutant phenotype] 7982894, Weak b2522 ECK120002187 pepB b2523 2655075 2656358 reverse aminopeptidase B b2523 ECK120002188 iscX b2524 2656536 2656736 reverse accessory iron-sulfur cluster assembly protein IscX [EXP-IDA|W|Inferred from direct assay] 10393315,20404999,24810328,26560204, Weak b2524 ECK120001299 fdx b2525 2656748 2657083 reverse reduced ferredoxin [EXP|W|Inferred from experiment] 10393315,11983079,1512212,15496591,23682711,25688831,26560204,4927832, Weak b2525 ECK120002032 hscA b2526 2657085 2658935 reverse iron-sulfur cluster biosynthesis chaperone HscA [EXP-IMP|W|Inferred from mutant phenotype] 10544286,16511138,25682519,26246371,26560204, Weak b2526 ECK120002033 hscB b2527 2658952 2659467 reverse [Fe-S] cluster biosynthesis co-chaperone HscB [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 10544286,10869428,11432781,11994302,12871959,15496591,18702525, Weak b2527 ECK120002034 iscA b2528 2659563 2659886 reverse iron-sulfur cluster insertion protein IscA 10544286, b2528 ECK120003896 iscU b2529 2659903 2660289 reverse scaffold protein for iron-sulfur cluster assembly [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 15964837,22348472,22352884,22734684,23068614,23812717,25307727,25688831,28640740,32142206,32143036, Weak b2529 ECK120003897 iscS b2530 2660317 2661531 reverse cysteine desulfurase IscS 11752417,12382038, b2530 ECK120003898 iscR b2531 2661643 2662131 reverse DNA-binding transcriptional dual regulator IscR [EXP-IEP|W|Inferred from expression pattern] 11742080, Weak b2531 ECK120003899 trmJ b2532 2662583 2663323 reverse tRNA Cm32/Um32 methyltransferase 26202969, b2532 ECK120000972 suhB b2533 2663442 2664245 forward Nus factor SuhB 19706412,7730297, b2533 ECK120003900 yfhR b2534 2664390 2665244 forward putative peptidase b2534 ECK120003901 csiE b2535 2665435 2666715 forward stationary phase-inducible protein CsiE 21695786,23124973,8596457, b2535 ECK120003902 hcaT b2536 2666707 2667846 reverse putative 3-phenylpropionate transporter 16397293,6345502, b2536 ECK125140822 iroK b4706 2668006 2668071 reverse protein IroK [EXP-IMP|W|Inferred from mutant phenotype] 22161628, Weak b4706 ECK120003903 hcaR b2537 2668006 2668896 reverse DNA-binding transcriptional dual regulator HcaR 15808934,9603882, b2537 ECK120004468 hcaE b2538 2669032 2670393 forward putative 3-phenylpropionate/cinnamate dioxygenase subunit α b2538 ECK120004474 hcaF b2539 2670390 2670908 forward putative 3-phenylpropionate/cinnamate dioxygenase subunit β b2539 ECK120003904 hcaC b2540 2670908 2671228 forward putative 3-phenylpropionate/cinnamate dioxygenase ferredoxin subunit b2540 ECK120003905 hcaB b2541 2671225 2672037 forward 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase b2541 ECK120003906 hcaD b2542 2672047 2673249 forward putative 3-phenylpropionate/cinnamate dioxygenase ferredoxin reductase subunit b2542 ECK120003907 yphA b2543 2673346 2673768 forward putative inner membrane protein b2543 ECK120003908 yphB b2544 2673816 2674688 reverse putative aldose 1-epimerase YphB [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 29535276, Weak b2544 ECK120003909 yphC b2545 2674700 2675761 reverse putative zinc-binding dehydrogenase YphC b2545 ECK120003910 yphD b2546 2675827 2676825 reverse putative ABC transporter membrane subunit YphD 31438868, b2546 ECK120003911 yphE b2547 2676850 2678361 reverse putative ABC transporter ATP-binding protein YphE 31438868, b2547 ECK120003912 yphF b2548 2678384 2679367 reverse putative ABC transporter periplasmic binding protein YphF 31438868, b2548 ECK120003913 yphG b2549 2679464 2682745 reverse DUF5107 domain-containing protein YphG b2549 ECK120003914 yphH b2550 2682863 2684056 forward putative DNA-binding transcriptional regulator, NAGC-like b2550 ECK120000401 glyA b2551 2684254 2685507 reverse serine hydroxymethyltransferase 23128557,23192292,23824318,24516157, b2551 ECK120000449 hmp b2552 2685835 2687025 forward nitric oxide dioxygenase 11690654,1325799,23208089,23824318,25193663,26389555,27166377,27767067,7821669,7875569,8226691, b2552 ECK120000377 glnB b2553 2687070 2687408 reverse nitrogen regulatory protein PII-1 [EXP-IMP|W|Inferred from mutant phenotype],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10074086,25557370,7961766,9209053, Strong b2553 ECK120001258 glrR b2554 2687469 2688803 reverse DNA-binding transcriptional activator GlrR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 10734204,15522865,15556475,19843219, Weak b2554 ECK120002040 qseG b2555 2688793 2689506 reverse outer membrane lipoprotein QseG [EXP-IDA|W|Inferred from direct assay] 27629414,30040820,32053772, Weak b2555 ECK120003915 glrK b2556 2689671 2691098 reverse histidine kinase GlrK b2556 ECK120002620 glmY b4441 2691157 2691340 reverse small regulatory RNA GlmY [EXP-IMP|W|Inferred from mutant phenotype] 17854828,19734312,22355164,22661574,26531825,28977623,30040820, Weak b4441 ECK120000788 purL b2557 2691656 2695543 reverse phosphoribosylformylglycinamide synthetase b2557 ECK120001341 mltF b2558 2695801 2697357 forward membrane-bound lytic murein transglycosylase F 11139297,8203016,9158737, b2558 ECK120001340 tadA b2559 2697354 2697857 reverse tRNA adenosine deaminase 1602968,16142903, b2559 ECK120001339 pgpC b2560 2697915 2698550 reverse phosphatidylglycerophosphatase C b2560 ECK120002185 yfhH b2561 2698759 2699607 forward putative DNA-binding transcriptional regulator YfhH [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 10734204,15556475, Weak b2561 ECK120003916 yfhL b2562 2699663 2699923 forward putative 4Fe-4S cluster-containing protein YfhL 31358606, b2562 ECK120030081 ryfB b4607 2700059 2700377 reverse b4607 ECK120035076 shoB b4687 2700117 2700197 reverse toxic peptide ShoB [EXP-IMP|W|Inferred from mutant phenotype] 18710431, Weak b4681,b4687 ECK120030082 ohsC b4608 2700520 2700598 forward small regulatory RNA OhsC [EXP-IMP|W|Inferred from mutant phenotype] 18710431, Weak b4608 ECK120000241 acpS b2563 2700618 2700998 reverse holo-[acyl-carrier-protein] synthase b2563 ECK120000685 pdxJ b2564 2700998 2701729 reverse pyridoxine 5'-phosphate synthase 15094056,15242009,8636054,8971718, b2564 ECK120000823 recO b2565 2701741 2702469 reverse recombination mediator protein RecO [EXP-IDA|W|Inferred from direct assay],[EXP-IGI|W|Inferred from genetic interaction] 11743007,12769856,15687199,21504984,22976180,25170075,26874520,27974172,2823066,2841571,2993230,33450019,7862097,8107098,9048946,9537373, Weak b2565 ECK120000264 era b2566 2702481 2703386 reverse 30S ribosomal subunit maturation GTPase Era [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 10937433,11917006,12125819,12753192,1526446,16825789,17272300,17651431,1823587,1925028,20188109,2029511,22246579,22750478,23650596,30076205,32817092,7721709,7729673,7876255,8057845,8282709,8807801,9093842, Weak b2566 ECK120000848 rnc b2567 2703383 2704063 reverse RNase III 2983317, b2567 ECK120000523 lepB b2568 2704335 2705309 reverse signal peptidase I 10692453,10891078,10982814,14705954,15195997,15598653,16126156,18032415,18177734,18315846,22031009,2243078,2406254,2644209,28038943,3036831,33989648,34492253,6395892,8262975, b2568 ECK120000522 lepA b2569 2705325 2707124 reverse 30S ribosomal subunit biogenesis factor LepA [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 17110332,20045415,21300907,21930951,22411911,22965132,23431150,23951009,28096346, Weak b2569 ECK120003917 rseC b2570 2707322 2707801 reverse protein RseC [EXP-IMP|W|Inferred from mutant phenotype] 12773378, Weak b2570 ECK120003918 rseB b2571 2707798 2708754 reverse anti-sigma factor stabilizing protein RseB b2571 ECK120002216 rseA b2572 2708754 2709404 reverse anti-sigma-E factor RseA [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IPI|W|Inferred from physical interaction] 11442831,12670975,16855227,9159522,9159523, Weak b2572 ECK120001827 rpoE b2573 2709437 2710012 reverse RNA polymerase sigma factor RpoE [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 29992897,7889935, Weak b2573 ECK125256960 rseD b4725 2710009 2710164 reverse leader peptide 28924029, b4725 ECK120000624 nadB b2574 2710420 2712042 forward L-aspartate oxidase 28700220, b2574 ECK120001492 yfiC b2575 2712027 2712764 reverse tRNA mA37 methyltransferase b2575 ECK120000964 srmB b2576 2712896 2714230 forward ATP-dependent RNA helicase SrmB 23472115,27388791,31188443,31877323, b2576 ECK120001719 yfiE b2577 2714439 2715320 reverse putative LysR-type DNA-binding transcriptional regulator YfiE [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b2577 ECK120002298 eamB b2578 2715423 2716010 forward cysteine/-acetylserine exporter EamB 10322417,12562784, b2578 ECK120001718 grcA b2579 2716066 2716449 reverse stress-induced alternate pyruvate formate-lyase subunit [EXP|W|Inferred from experiment],[EXP-IMP|W|Inferred from mutant phenotype] 11444864,19282968,34801558, Weak b2579 ECK120001047 ung b2580 2716754 2717443 forward uracil-DNA glycosylase 10200172,11027138,11035036,11087352,12033946,12057944,12136091,12184783,12206669,12705824,12725863,12888518,1359874,14585934,16908222,18652484,1886771,20056657,2018771,2192282,21971549,24740413,2997126,30590231,342701,365859,3889834,6109711,6234205,6282808,6999365,7720873,7937085,8063831,8960131,9171083,9261156,9469838, b2580 ECK120001720 yfiF b2581 2717491 2718528 reverse putative methyltransferase YfiF [EXP-IMP|W|Inferred from mutant phenotype] 34486756, Weak b2581 ECK120001817 trxC b2582 2718735 2719154 forward reduced thioredoxin 2 [EXP|W|Inferred from experiment] 21570393,9388228, Weak b2582 ECK120003919 tapT b2583 2719223 2719921 forward tRNA 3-amino-3-carboxypropyltransferase 25566315,4598734, b2583 ECK120003920 patZ b2584 2719953 2722613 forward peptidyl-lysine -acetyltransferase b2584 ECK125286410 pssL b4782 2722702 2722743 forward protein PssL b4782 ECK120000772 pssA b2585 2722727 2724082 forward phosphatidylserine synthase 14213340,14634719,187212,195963,211116,22503979,2982784,3011772,3531205,3918012,4603221,49056,6268933,6361023,6391555,8824831,8829529,9139902, b2585 ECK120002404 yfiM b2586 2724128 2724451 forward DUF2279 domain-containing protein YfiM 24391520, b2586 ECK120000515 kgtP b2587 2724448 2725746 reverse α-ketoglutarate:H symporter b2587 ECK125286422 yfiS b4783 2725925 2725987 forward protein YfiS b4783 ECK120002517 rrfG b2588 2726069 2726188 reverse 5S ribosomal RNA [EXP-TAS|W|Traceable author statement to experimental support] 11401702,11488615,164889,1709493,1709723,1718749,1764510,2190187,2412207,2493632,3013618,3089782,324975,327272,331075,3315008,342117,359042,4198187,4216514,4550693,4571522,4591367,4609878,4621557,4881049,4881332,4906324,4906608,4918254,4920877,4924729,4931952,4944480,4993318,6178431,6188537,6255417,6390428,6765232,7024913,782717,805122,810137,95791,9862991,9878392, Weak b2588 ECK120002524 rrlG b2589 2726281 2729184 reverse 23S ribosomal RNA [EXP-TAS|W|Traceable author statement to experimental support] 10051579,10464195,10525403,10793686,10844684,1094419,10964562,10986461,1098691,1101264,1102922,1103090,1103124,11157269,11350034,11517305,11574482,11675490,11680845,11741781,11751827,11888286,11955006,11991636,12022228,12034826,12467398,12498,12533472,12888505,1719209,1918155,1981803,2197598,2407189,2473375,3013618,3048270,3053641,3060850,3089782,319193,319197,3226909,325525,327272,327273,3277949,329865,331075,331313,3313279,3329282,342117,355851,359042,388189,3894326,390405,407931,4563865,4584388,4918356,4931952,4942898,4943519,6158039,6162473,6170632,6173374,6193815,6255418,6349628,6361011,6750359,6996708,7016337,7041903,7514294,7529560,7567991,7601845,7682175,775291,782716,782717,785385,789334,791272,8031879,805122,8253085,8515441,8524828,8643399,8643630,8654409,8710862,8834779,8918803,9016593,9034358,9135982,9367788,9396814,9501232,9573162,9586034,9620960,9769102,9836593,9989214, Weak b2589 ECK120002477 gltW b2590 2729369 2729444 reverse tRNA-Glu(UUC) [AS-TAS|W|Traceable author statement] 7033244, Weak b2590 ECK120002531 rrsG b2591 2729616 2731157 reverse 16S ribosomal RNA 10753935,10844684,10919826,1094419,1101264,1102922,1103124,110460,11751827,12087167,12498,12902289,12903214,14510386,1646122,1716101,1718749,1764510,1764516,2145040,2168847,2222527,2387410,2435709,2443830,2448485,2473375,2685545,2689447,2833391,3013618,3071662,3071664,319193,320561,326259,327272,327273,3277949,331075,331313,3313279,3329282,342117,344139,348233,365689,378405,383432,384145,3894326,390405,392468,407931,4560773,4564202,4918356,4942898,4943519,6285294,6330033,6361011,6752954,6995826,7516168,7601845,769922,7718670,782716,782717,789334,793615,8041615,8312257,8377198,8419334,8515441,9034358,9226253,9501232,9769102, b2591 ECK120000153 clpB b2592 2731600 2734173 reverse ClpB80 30904393,8376377, b2592 ECK120000153 clpB b2592 2731600 2734173 reverse protein disaggregase ClpB 30904393,8376377, b2592 ECK120030083 ryfD b4609 2734153 2734295 reverse small regulatory RNA RyfD [EXP-IMP|W|Inferred from mutant phenotype] 26469694, Weak b4609 ECK120002002 yfiH b2593 2734303 2735034 reverse purine nucleoside phosphorylase YfiH b2593 ECK120002003 rluD b2594 2735031 2736011 reverse 23S rRNA pseudouridine synthase 27661780,28334881,8871555, b2594 ECK120003921 bamD b2595 2736146 2736883 forward outer membrane protein assembly factor BamD [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 16824102,20378773,21139201,21228468,26900875,32053772,34070637, Strong b2595 ECK120003922 Phantom Gene b2596 2736913 2737119 forward b2596 ECK120001134 raiA b2597 2737154 2737495 forward ribosome-associated inhibitor A [EXP-IDA|W|Inferred from direct assay],[EXP|W|Inferred from experiment] 10535924,11375931,15502846,17277072,23420694,32649051, Weak b2597 ECK125289863 raiZ b4805 2737381 2737542 forward small RNA RaiZ b4805 ECK120001245 pheL b2598 2737599 2737646 forward operon leader peptide [EXP-IDA|W|Inferred from direct assay] 14592990, Weak b2598 ECK120000699 pheA b2599 2737745 2738905 forward fused chorismate mutase/prephenate dehydratase b2599 ECK120001028 tyrA b2600 2738948 2740069 reverse fused chorismate mutase/prephenate dehydrogenase b2600 ECK120000074 aroF b2601 2740080 2741150 reverse 3-deoxy-7-phosphoheptulonate synthase, Tyr-sensitive 2903857, b2601 ECK120002299 yfiL b2602 2741360 2741725 forward DUF2799 domain-containing lipoprotein YfiL b2602 ECK120003923 yfiR b2603 2741875 2742393 forward DUF4154 domain-containing protein YfiR [EXP-IMP|W|Inferred from mutant phenotype] 17941710, Weak b2603 ECK120002419 dgcN b2604 2742383 2743609 forward diguanylate cyclase DgcN [EXP-IGI|W|Inferred from genetic interaction] 20303158,23202856, Weak b2604 ECK120001135 yfiB b2605 2743625 2744107 forward lipoprotein YfiB 32053772, b2605 ECK120000871 rplS b2606 2744183 2744530 reverse 50S ribosomal subunit protein L19 339951,340794,368561,368562,378264,387084,3905404,4595567,4614072,6345195,6357787,6359156,6361486,6381990,6450872,68433,7024914,799248, b2606 ECK120001012 trmD b2607 2744572 2745339 reverse tRNA mG37 methyltransferase 15165845,26140378,26965259,29495922,34123232, b2607 ECK120001136 rimM b2608 2745370 2745918 reverse ribosome maturation factor RimM [EXP|W|Inferred from experiment] 17616598,24207057,27382067,30219894,9422595, Weak b2608 ECK120000906 rpsP b2609 2745937 2746185 reverse 30S ribosomal subunit protein S16 23972210,359353, b2609 ECK120000294 ffh b2610 2746434 2747795 reverse signal recognition particle protein component [EXP-IMP|W|Inferred from mutant phenotype],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 11976293,12423355,20923772,7612669,8706678,9305630, Strong b2610 ECK120003924 ypjD b2611 2747962 2748753 forward cytochrome assembly family protein b2611 ECK120002295 yfjD b4461 2748774 2750060 forward UPF0053 family inner membrane protein YfjD 31438868, b2612,b2613,b4461 ECK120000409 grpE b2614 2750115 2750708 reverse nucleotide exchange factor GrpE b2614 ECK120002081 nadK b2615 2750831 2751709 forward NAD kinase 11488932, b2615 ECK120000822 recN b2616 2751795 2753456 forward DNA repair protein RecN [EXP-IMP|W|Inferred from mutant phenotype] 10931361,11333217,1883889,19399845,23974212,24615185,28262707,29468195,2993876,3037486,30422330,31208335,31754643,32816866,3283110,3526390,6092851,6343801,6344125,8349557,9862197, Weak b2616 ECK120000941 bamE b2617 2753605 2753946 forward outer membrane protein assembly factor BamE [COMP-HINF|W|Inferred by a human based on computational evidence],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IPI|W|Inferred from physical interaction] 11133948,14526028,17404237,2045357,26900875,31113900,31113901,32053772, Weak b2617 ECK120003925 yfjF b2618 2754008 2754298 reverse putative component of the Rsx system 21323758,32558363, b2618 ECK120003926 ratA b2619 2754288 2754764 reverse ribosome association toxin RatA [EXP|W|Inferred from experiment] 21323758,32558363, Weak b2619 ECK120001716 smpB b2620 2754896 2755378 forward SsrA-binding protein [EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ],[EXP-IMP|W|Inferred from mutant phenotype] 11917023,2045357,28334975, Weak b2620 ECK120002542 ssrA b2621 2755593 2755955 forward tmRNA [EXP-IDA|W|Inferred from direct assay] 10449423,11459181,12533482,1695897,7511583,9150876, Weak b2621 ECK120001717 intA b2622 2756159 2757400 forward CP4-57 prophage; integrase IntA b2622 ECK120003927 yfjH b2623 2757644 2758600 reverse CP4-57 prophage; uncharacterized protein YfjH b2623 ECK120002016 alpA b2624 2758644 2758856 forward CP4-57 prophage; DNA-binding transcriptional activator AlpA [EXP-IMP|W|Inferred from mutant phenotype] 7511582, Weak b2624 ECK120003928 yfjI b2625 2758985 2760394 forward CP4-57 prophage; DUF3987 domain-containing protein YfjI b2625 ECK120003929 yfjJ b2626 2760547 2761173 forward CP4-57 prophage; protein YfjJ b2626 ECK120003930 abpB b2627 2761351 2763540 reverse CP4-57 prophage; putative helicase YfjK [EXP-IMP|W|Inferred from mutant phenotype] 19502398,24596156,25224971, Weak b2627 ECK120003931 abpA b2628 2763537 2765153 reverse CP4-57 prophage; anti-bacteriophage protein [EXP-IMP|W|Inferred from mutant phenotype] 22731697,24391520,25224971, Weak b2628 ECK120003932 yfjM b2629 2765513 2765776 reverse CP4-57 prophage; protein YfjM b2629 ECK120003933 rnlA b2630 2765918 2766991 forward CP4-57 prophage; RNase LS, toxin of the RnlAB toxin-antitoxin system b2630 ECK120003934 rnlB b2631 2766984 2767355 forward CP4-57 prophage; antitoxin RnlB [EXP-IMP|W|Inferred from mutant phenotype] 20980243,25912447,28085056, Weak b2631 ECK120003935 yfjP b2632 2767710 2768573 forward CP4-57 prophage; putative GTP-binding protein YfjP b2632 ECK120003936 yfjQ b2633 2768665 2769486 forward CP4-57 prophage; DUF932 domain-containing protein YfjQ b2633 ECK120003937 yfjR b2634 2769703 2770404 forward CP4-57 prophage; putative DNA-binding transcriptional regulator YfjR [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 15556475,16385049,24391520, Weak b2634 ECK120003938 ypjK b2635 2770445 2770681 forward CP4-57 prophage; uncharacterized protein YpjK b2635 ECK120003939 yfjS b2636 2770681 2771124 forward CP4-57 prophage; inner membrane lipoprotein YfjS 32053772, b2636 ECK120003940 yfjT b2637 2771148 2771615 forward CP4-57 prophage; uncharacterized protein YfjT b2637 ECK120003941 yfjU b2638 2771840 2772154 reverse CP4-57 prophage; putative arsenate reductase-like protein YfjU b2638 ECK120003944 yfjV b2641 2772167 2773182 reverse CP4-57 prophage; putative arsenite transporter b2639,b2640,b2641 ECK120003945 yfjW b2642 2773318 2775021 forward CP4-57 prophage; uncharacterized protein YfjW b2642 ECK125240966 ypjI b4644 2775545 2775816 forward putative UPF0401 protein YpjI b4644 ECK120003946 yfjX b2643 2775919 2776377 forward CP4-57 prophage; putative antirestriction protein YfjX b2643 ECK120003947 yfjY b2644 2776386 2776868 forward CP4-57 prophage; RadC-like JAB domain-containing protein YfjY b2644 ECK120016316 ypjJ b4548 2776877 2777077 forward CP4-57 prophage; DUF987 domain-containing protein YpjJ b4548 ECK120003948 yfjZ b2645 2777115 2777432 forward CP4-57 prophage; putative antitoxin of the YpjF-YfjZ toxin-antitoxin system b2645 ECK120003949 ypjF b2646 2777453 2777782 forward CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system b2646 ECK125240973 psaA b4645 2777972 2777985 forward b4645 ECK120003950 ypjA b2647 2778146 2782726 reverse adhesin-like autotransporter YpjA b2647 ECK120003951 pinH b2648 2783065 2783304 reverse putative invertase fragment b2648 ECK120003952 ypjB b2649 2783638 2784429 reverse DUF5508 domain-containing protein YpjB b2649 ECK120003953 ypjC b2650 2784529 2785011 reverse DUF5507 domain-containing protein YpjC b2650 ECK120003954 b2651 b2651 2785221 2785352 forward ECK120003955 ileY b2652 2785762 2785837 reverse tRNA-Ile(CAU) [AS-TAS|W|Traceable author statement] 7033244, Weak b2652 ECK120003956 Phantom Gene b2653 2785800 2785973 reverse b2653 ECK120003957 ygaQ b4462 2786397 2788649 forward putative uncharacterized protein YgaQ 32268068, b2654,b2655,b2656,b2657,b2658,b4462 ECK120003961 glaH b2659 2788985 2789962 forward glutarate dioxygenase GlaH 9512707, b2659 ECK120002252 lhgD b2660 2789982 2791250 forward L-2-hydroxyglutarate dehydrogenase b2660 ECK120001300 gabD b2661 2791273 2792721 forward succinate-semialdehyde dehydrogenase (NADP) GabD 2254272,8297211, b2661 ECK120000354 gabT b2662 2792735 2794015 forward 4-aminobutyrate aminotransferase GabT 20729367,22636776,26838342,28338893,28727911, b2662 ECK120001301 gabP b2663 2794253 2795653 forward 4-aminobutanoate:H symporter b2663 ECK120002251 glaR b2664 2795674 2796336 forward DNA-binding transcriptional repressor GlaR [EXP-IMP|W|Inferred from mutant phenotype],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 12446648,2188954,24037,28061857,30498244, Strong b2664 ECK120003962 kbp b2665 2796337 2796786 reverse K binding protein [EXP-IDA|W|Inferred from direct assay] 27112601, Weak b2665 ECK120003963 yqaE b2666 2796870 2797028 reverse Pmp3 family protein YqaE 25246476, b2666 ECK120003964 ygaV b2667 2797211 2797510 forward putative DNA-binding transcriptional regulator YgaV [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 15556475,18245262, Weak b2667 ECK120003965 ygaP b2668 2797520 2798044 forward thiosulfate sulfurtransferase YgaP b2668 ECK120001507 stpA b2669 2798091 2798495 reverse DNA-binding transcriptional repressor StpA with RNA chaperone activity [EXP|W|Inferred from experiment] Weak b2669 ECK120003966 alaE b2670 2799164 2799613 forward L-alanine exporter 19767843, b2670 ECK120002089 ygaC b2671 2799650 2799994 reverse DUF2002 domain-containing protein YgaC b2671 ECK120003967 ygaM b2672 2800146 2800475 forward DUF883 domain-containing protein YgaM b2672 ECK120003968 nrdH b2673 2800723 2800968 forward glutaredoxin-like protein NrdH [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 9218434, Weak b2673 ECK120003969 nrdI b2674 2800965 2801375 forward dimanganese-tyrosyl radical cofactor maintenance flavodoxin NrdI [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 18799738,21250660, Weak b2674 ECK120002450 nrdE b2675 2801348 2803492 forward ribonucleoside-diphosphate reductase 2 subunit α b2675 ECK120002248 nrdF b2676 2803502 2804461 forward ribonucleoside-diphosphate reductase 2 subunit β b2676 ECK120000762 proV b2677 2804815 2806017 forward glycine betaine ABC transporter ATP binding subunit ProV 22257006,28911185, b2677 ECK120000763 proW b2678 2806010 2807074 forward glycine betaine ABC transporter membrane subunit ProW b2678 ECK120000764 proX b2679 2807132 2808124 forward glycine betaine ABC transporter periplasmic binding protein ProX 11223528, b2679 ECK120003970 ygaY b2681 2808316 2809493 forward putative transporter YgaY, N-terminal fragment 12620868,14526028, b2680,b2681 ECK120003972 ygaZ b2682 2809617 2810354 forward L-valine exporter, YgaZ component b2682 ECK120003973 ygaH b2683 2810344 2810679 forward L-valine exporter, YgaH component 31438868, b2683 ECK120000596 mprA b2684 2810770 2811300 forward DNA-binding transcriptional regulator MprA b2684 ECK120001323 emrA b2685 2811427 2812599 forward multidrug efflux pump membrane fusion protein EmrA 24996185,27105118,30578262, b2685 ECK120001403 emrB b2686 2812616 2814154 forward multidrug efflux pump membrane subunit EmrB 27105118,8509326, b2686 ECK120002369 luxS b2687 2814218 2814733 reverse -ribosylhomocysteine lyase 22176949,23226268,23246794, b2687 ECK120002578 micA b4442 2814802 2814874 forward small regulatory RNA MicA [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 11448770,16204185,16313626,20976191,23594456,24163336,24244437,25030700,25046628,29467745,30287822, Weak b4442 ECK120000411 gshA b2688 2814883 2816439 reverse glutamate—cysteine ligase 11703177,9188456, b2688 ECK120003974 yqaA b2689 2816512 2816940 reverse DedA family protein YqaA b2689 ECK120003975 yqaB b2690 2816937 2817503 reverse fructose-1-phosphate phosphatase YqaB b2690 ECK120002456 argQ b2691 2817784 2817860 reverse tRNA-Arg(ACG) [AS-TAS|W|Traceable author statement] 7033244, Weak b2691 ECK120002462 argZ b2692 2818059 2818135 reverse tRNA-Arg(ACG) [AS-TAS|W|Traceable author statement] 7033244, Weak b2692 ECK120002461 argY b2693 2818198 2818274 reverse tRNA-Arg(ACG) [AS-TAS|W|Traceable author statement] 7033244, Weak b2693 ECK120002458 argV b2694 2818473 2818549 reverse tRNA-Arg(ACG) [AS-TAS|W|Traceable author statement] 7033244, Weak b2694 ECK120002537 serV b2695 2818553 2818645 reverse tRNA-Ser(GCU) [AS-TAS|W|Traceable author statement] 7033244, Weak b2695 ECK120001410 csrA b2696 2818961 2819146 reverse carbon storage regulator 28334975,8366066,8393005, b2696 ECK120000031 alaS b2697 2819381 2822011 reverse alanine—tRNA ligase/DNA-binding transcriptional repressor 20179335,23536244,24493149,25918376,27622773, b2697 ECK120001986 recX b2698 2822139 2822639 reverse RecA inhibitor RecX [EXP-IDA|W|Inferred from direct assay] 12055302,12218174,12427742,19116657,19555451,21143322,21790018,22954223,7512687,8165147, Weak b2698 ECK120000814 recA b2699 2822708 2823769 reverse DNA recombination/repair protein RecA [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 10047484,10074404,10444598,10542196,10692372,10731413,10733533,10829063,10835273,1103845,11061970,11084028,11152126,11181060,11219855,11230142,11230150,11459984,11470894,11491297,11503517,11504729,11560883,11734008,11916875,11929519,12096908,12218174,12456687,12598538,12741852,12741853,12842880,12903344,1400177,1400384,1438275,14529621,14530291,14556640,14680809,15138263,15267169,15315951,15364575,15454450,15719060,15744322,15824062,159453,1606138,16351198,16421856,1644827,1644828,1653032,1654503,16756994,16834432,16847846,16946710,16988658,16990254,17141804,17151069,1715863,1731253,17449010,18166039,18296520,1830922,18497818,18603529,18627467,1883879,1883882,1883886,19004837,1911941,19338667,19514040,19555451,1962209,19820696,19910465,20044347,2014257,20507912,2082728,20886744,20953173,21143322,21193798,2141651,21458462,2147430,2157980,21697094,21764927,21768124,2179566,2186808,2190981,2228969,22318518,22521886,225671,22633148,22941658,23103864,23103870,23224554,23825559,23944487,23965307,2406267,24362571,24371286,2554312,25559557,25561575,25785454,26047498,26196253,26261330,26315438,26384422,26481664,2651400,2693734,27001450,27043933,27124470,27130282,27499708,27587394,2793864,28049371,28101376,28262707,2830283,2836358,2841294,28476890,28854739,28928411,28934502,28977583,29097773,2939874,2946663,29468195,2948553,2951381,2953903,2958446,29789437,2981202,30013537,3009481,30137528,30285153,3036851,30482842,3063827,3063828,30717823,30792518,30900876,30916331,30975899,3126496,31372639,3159017,3160686,3160687,3172227,32788357,32816866,3295259,3298251,33057191,3309327,3314992,33382157,33526493,33573045,33605213,34197804,34702889,3511041,3536864,3543003,370822,379861,4205905,4600265,6213837,6217403,6222041,6231641,6238224,6240586,6244589,6263487,6283318,6313216,6313656,6343787,6444245,6446716,6447873,6452577,6454691,6455420,6455429,6455430,6461657,6572385,6751562,6754721,6941272,6994103,7019209,7021552,7021553,7021554,7026047,7031062,7047518,7500959,7528894,7588783,7616568,7625276,7657604,7687008,7709802,7746854,792876,792880,7962001,8051165,8106426,8132511,8132549,8133517,8226685,8355662,8367479,8371266,8377192,8407828,8456313,8496964,8606178,8621438,8636980,8655553,8702471,8798617,8798618,8980679,9044260,9048946,9109676,9131997,9201926,9211918,9398528,9512712,9606202,9709007,9973561,9973562, Weak b2699 ECK120003976 pncC b2700 2823849 2824346 reverse NMN aminohydrolase b2700 ECK120003977 mltB b2701 2824491 2825576 reverse membrane-bound lytic murein transglycosylase B 10037771,10542235,10806384,11084598,11139297,11544210,12399477,12949085,15126489,15576800,15601715,15793119,29802191,32053772,8405923, b2701 ECK120004460 srlA b2702 2825832 2826395 forward sorbitol-specific PTS enzyme IIC component 31438868, b2702 ECK120000958 srlE b2703 2826392 2827351 forward sorbitol-specific PTS enzyme IIBC component 31438868, b2703 ECK120000959 srlB b2704 2827362 2827733 forward sorbitol-specific PTS enzyme IIA component b2704 ECK120000960 srlD b2705 2827737 2828516 forward sorbitol-6-phosphate 2-dehydrogenase 3036766, b2705 ECK120000961 gutM b2706 2828621 2828980 forward DNA-binding transcriptional activator GutM [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern] 3062173, Weak b2706 ECK120000963 srlR b2707 2829047 2829820 forward DNA-binding transcriptional repressor SrlR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern] 3062173,31608580, Weak b2707 ECK120000962 gutQ b2708 2829813 2830778 forward D-arabinose 5-phosphate isomerase GutQ b2708 ECK120002013 norR b2709 2830775 2832289 reverse DNA-binding transcriptional dual regulator NorR [EXP-IDA|W|Inferred from direct assay],[EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 11751865,12142437,12529359,14718666,15375149,16193057,7894055, Weak b2709 ECK120003978 norV b2710 2832476 2833915 forward anaerobic nitric oxide reductase flavorubredoxin b2710 ECK120002302 norW b2711 2833912 2835045 forward NADH:flavorubredoxin reductase 12586421,18021800,21265775,22563051, b2711 ECK120002621 C0664 2835055 2835167 forward ECK120001504 hypF b2712 2835173 2837425 reverse carbamoyl--[HypE] ligase 1107810,22153500,23271421,25184670,26049001,26186649,30161297,3884594,3884595, b2712 ECK120001505 hydN b2713 2837578 2838105 reverse putative electron transport protein HydN [EXP-IMP|W|Inferred from mutant phenotype] 8661925, Weak b2713 ECK120000083 ascG b2714 2838254 2839264 reverse DNA-binding transcriptional repressor AscG [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 1630307,19633077, Strong b2714 ECK120000082 ascF b2715 2839524 2840981 forward β-glucoside specific PTS enzyme IIBC component b2715 ECK120000081 ascB b2716 2840990 2842414 forward 6-phospho-β-glucosidase AscB b2716 ECK120003979 hycI b2717 2842573 2843043 reverse hydrogenase 3 maturation protease b2717 ECK120000474 hycH b2718 2843036 2843446 reverse formate hydrogenlyase assembly protein [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 28718449, Weak b2718 ECK120000473 hycG b2719 2843443 2844210 reverse formate hydrogenlyase subunit HycG b2719 ECK120000472 hycF b2720 2844210 2844752 reverse formate hydrogenlyase subunit HycF b2720 ECK120000471 hycE b2721 2844762 2846471 reverse formate hydrogenlyase subunit HycE 31925988, b2721 ECK120000470 hycD b2722 2846489 2847412 reverse formate hydrogenlyase subunit HycD b2722 ECK120000469 hycC b2723 2847415 2849241 reverse formate hydrogenlyase subunit HycC b2723 ECK120000468 hycB b2724 2849238 2849849 reverse formate hydrogenlyase subunit HycB 29942290, b2724 ECK120000467 hycA b2725 2849974 2850435 reverse regulator of the transcriptional regulator FhlA [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 15556475,1625581, Weak b2725 ECK120000476 hypA b2726 2850647 2850997 forward hydrogenase 3 nickel incorporation protein HypA [EXP-IMP|W|Inferred from mutant phenotype] 1482271, Weak b2726 ECK120000477 hypB b2727 2851001 2851873 forward hydrogenase isoenzymes nickel incorporation protein HypB 34302342, b2727 ECK120000478 hypC b2728 2851864 2852136 forward hydrogenase maturation factor HypC [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 26364315,9485446, Weak b2728 ECK120000479 hypD b2729 2852136 2853257 forward Fe-(CN)CO cofactor assembly scaffold protein HypD [EXP-IMP|W|Inferred from mutant phenotype] 1482271,25211029,2536683,3056901, Weak b2729 ECK120000480 hypE b2730 2853254 2854264 forward carbamoyl dehydratase HypE [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 12586941,15184145,2157623,25184670,2848007,3332683,34409988,3884594,3884595, Weak b2730 ECK120000295 fhlA b2731 2854338 2856416 forward DNA-binding transcriptional activator FhlA 2118503,2280686,8034727, b2731 ECK120001260 ygbA b2732 2856453 2856806 reverse protein YgbA 18433631, b2732 ECK120000618 mutS b2733 2857093 2859654 forward DNA mismatch repair protein MutS 12907723,19254532,3014530,30617079,33233554, b2733 ECK120003980 pphB b2734 2859760 2860416 forward phosphoprotein phosphatase 2 16079345, b2734 ECK120003981 ygbI b2735 2860467 2861234 reverse DNA-binding transcriptional repressor YgbI [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b2735 ECK120003982 ygbJ b2736 2861430 2862338 forward putative L-threonate dehydrogenase 27402745, b2736 ECK120003983 ygbK b2737 2862335 2863501 forward putative 3-oxo-tetronate kinase YgbK 24391520,27402745, b2737 ECK120003984 ygbL b2738 2863593 2864231 forward putative 3-oxo-tetronate 4-phosphate decarboxylase YgbL 27402745, b2738 ECK120003985 ygbM b2739 2864236 2865012 forward putative 2-oxo-tetronate isomerase YgbM 27402745, b2739 ECK120003986 ygbN b2740 2865101 2866465 forward putative transporter YgbN 31438868, b2740 ECK120000503 rpoS b2741 2866559 2867551 reverse RNA polymerase sigma factor RpoS [EXP|W|Inferred from experiment] 29992897,35087069, Weak b2741 ECK120002015 nlpD b2742 2867614 2868753 reverse murein hydrolase activator NlpD 22715947,32053772, b2742 ECK120000682 pcm b2743 2868893 2869519 reverse protein-L-isoaspartate -methyltransferase 10217780,32673742,7929130,9253175, b2743 ECK120001750 umpG b2744 2869513 2870274 reverse broad specificity 5'(3')-nucleotidase and polyphosphatase b2744 ECK120003987 truD b2745 2870255 2871304 reverse tRNA pseudouridine synthase b2745 ECK120001749 ispF b2746 2871301 2871780 reverse 2--methyl-D-erythritol 2,4-cyclodiphosphate synthase b2746 ECK120003988 ispD b2747 2871780 2872490 reverse 2--methyl-D-erythritol 4-phosphate cytidylyltransferase b2747 ECK120003989 ftsB b2748 2872509 2872820 reverse cell division protein FtsB [EXP-IMP|W|Inferred from mutant phenotype] 11972052,24083359,34070637, Weak b2748 ECK120002365 ygbE b2749 2873014 2873337 reverse DUF3561 domain-containing inner membrane protein YgbE b2749 ECK120000180 cysC b2750 2873387 2873992 reverse adenylyl-sulfate kinase b2750 ECK120000189 cysN b2751 2873992 2875419 reverse sulfate adenylyltransferase subunit 1 b2751 ECK120000181 cysD b2752 2875421 2876329 reverse sulfate adenylyltransferase subunit 2 b2752 ECK120000481 iap b2753 2876581 2877618 forward alkaline phosphatase isozyme conversion protein 6295883,7002151, b2753 ECK120002398 cas2 b2754 2878569 2878853 reverse CRISPR-associated endoribonuclease Cas2 b2754 ECK120003990 cas1 b2755 2878855 2879772 reverse multifunctional nuclease Cas1 b2755 ECK120003991 casE b2756 2879788 2880387 reverse pre-CRISPR RNA endonuclease 22781758,22918228,26013814, b2756 ECK120003992 casD b2757 2880374 2881048 reverse type I-E CRISPR system Cascade subunit CasD b2757 ECK120003993 casC b2758 2881051 2882142 reverse type I-E CRISPR system Cascade subunit CasC b2758 ECK120003994 casB b2759 2882155 2882637 reverse type I-E CRISPR system Cascade subunit CasB 23079036, b2759 ECK120003995 casA b2760 2882630 2884138 reverse type I-E CRISPR system Cascade subunit CasA 22521690,24748111, b2760 ECK120002345 cas3 b2761 2884553 2887219 reverse CRISPR-associated endonuclease/helicase Cas3 [EXP|W|Inferred from experiment],[EXP-IDA|W|Inferred from direct assay] 18703739,21699496,23406879,25123481,25326321,26956996, Weak b2761 ECK125135289 sokX b4701 2887353 2887411 forward small RNA SokX b4701 ECK120000184 cysH b2762 2887578 2888312 reverse phosphoadenosine phosphosulfate reductase b2762 ECK120000185 cysI b2763 2888387 2890099 reverse sulfite reductase, hemoprotein subunit 2158792,2966849,3301533,8395881,8457551, b2763 ECK120000186 cysJ b2764 2890099 2891898 reverse sulfite reductase, flavoprotein subunit b2764 ECK120003996 queD b2765 2892214 2892579 forward 6-carboxy-5,6,7,8-tetrahydropterin synthase b2765 ECK120003997 ygcN b2766 2892657 2893928 forward putative oxidoreductase with FAD/NAD(P)-binding domain b2766 ECK120003998 ygcO b2767 2893919 2894179 forward putative 4Fe-4S cluster-containing protein b2767 ECK120003999 ygcP b2768 2894196 2894771 forward putative anti-terminator regulatory protein b2768 ECK120004000 ygcQ b2769 2894919 2895779 reverse putative flavoprotein b2769 ECK120004001 ygcR b2770 2895776 2896555 reverse putative flavoprotein b2770 ECK120004002 ygcS b2771 2896533 2897870 reverse putative transporter YgcS 31438868, b2771 ECK120004003 ygcU b4463 2897964 2899418 reverse putative FAD-containing dehydrogenase b2772,b2773,b4463 ECK120004004 ygcW b2774 2899488 2900273 reverse putative deoxygluconate dehydrogenase b2774 ECK120002430 yqcE b2775 2900592 2901869 forward putative transport protein YqcE 31438868, b2775 ECK120004005 ygcE b2776 2901896 2903374 forward putative sugar kinase YgcE 33531410, b2776 ECK120004006 queE b2777 2904747 2905418 reverse putative 7-carboxy-7-deazaguanine synthase QueE b2777 ECK120048867 yqcG b4682 2905557 2905697 forward cell envelope stress response protein YqcG [EXP-IMP|W|Inferred from mutant phenotype] 19734312, Weak b4682 ECK120004007 ygcG b2778 2905711 2906583 forward TPM domain-containing protein YgcG b2778 ECK120000252 eno b2779 2906643 2907941 reverse enolase b2779 ECK120000801 pyrG b2780 2908029 2909666 reverse CTP synthetase b2780 ECK120000565 mazG b2781 2909894 2910685 reverse nucleoside triphosphate pyrophosphohydrolase b2781 ECK120001224 mazF b2782 2910756 2911091 reverse endoribonuclease toxin MazF b2782 ECK120000564 mazE b2783 2911091 2911339 reverse antitoxin of the MazF-MazE toxin-antitoxin system MazE b2783 ECK120000826 relA b2784 2911417 2913651 reverse GDP/GTP pyrophosphokinase 27279228, b2784 ECK120001223 rlmD b2785 2913699 2915000 reverse 23S rRNA mU1939 methyltransferase b2785 ECK120001335 barA b2786 2915057 2917813 forward sensor histidine kinase BarA b2786 ECK120004008 gudD b2787 2918045 2919385 reverse -glucarate dehydratase 6999115, b2787 ECK120004009 gudX b2788 2919406 2920746 reverse glucarate dehydratase-related protein b2788 ECK120004010 gudP b2789 2920748 2922100 reverse galactarate/D-glucarate transporter GudP 22705263,9772162, b2789 ECK120004011 yqcA b2790 2922535 2922984 reverse putative flavodoxin YqcA b2790 ECK120004012 truC b2791 2923002 2923784 reverse tRNA pseudouridine synthase b2791 ECK120004013 yqcC b2792 2923784 2924113 reverse DUF446 domain-containing protein YqcC 24391520, b2792 ECK120002573 csrB b4408 2924156 2924524 reverse small regulatory RNA CsrB [EXP-IDA|W|Inferred from direct assay] 11310739,11535784,11741870,16822857,17026754,17064377,18080813,20118252,24512078,24708042,28796489,30589862,9211896, Weak b4408 ECK120004014 syd b2793 2924735 2925280 reverse SecY-interacting protein [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 19139097, Weak b2793 ECK120004015 queF b2794 2925348 2926196 forward 7-cyano-7-deazaguanine reductase b2794 ECK120002241 ppnN b2795 2926308 2927672 forward nucleotide 5'-monophosphate nucleosidase b2795 ECK120002043 sdaC b2796 2928229 2929518 forward L-serine:H symporter SdaC b2796 ECK120001571 sdaB b2797 2929576 2930943 forward L-serine deaminase II b2797 ECK120002240 ygdG b2798 2931055 2931810 forward flap endonuclease [EXP-IDA|W|Inferred from direct assay] 23821668,7996866, Weak b2798 ECK120000345 fucO b2799 2931865 2933013 reverse L-1,2-propanediol oxidoreductase 20435762,21685167, b2799 ECK120000342 fucA b2800 2933041 2933688 reverse L-fuculose-phosphate aldolase b2800 ECK120000346 fucP b2801 2934235 2935551 forward L-fucose:H+ symporter 2834341,3005235,7961494, b2801 ECK120000343 fucI b2802 2935584 2937359 forward L-fucose isomerase b2802 ECK120000344 fucK b2803 2937468 2938886 forward L-fuculokinase 25078267,3325779,6378890, b2803 ECK120000348 fucU b2804 2938888 2939310 forward L-fucose mutarotase b2804 ECK120000347 fucR b2805 2939368 2940099 forward DNA-binding transcriptional activator FucR 2664711,3325779, b2805 ECK120001728 rlmM b2806 2940143 2941243 reverse 23S rRNA 2'--ribose C2498 methyltransferase 11293658, b2806 ECK120001727 ygdD b2807 2941236 2941631 reverse DUF423 domain-containing inner membrane protein YgdD 24391520, b2807 ECK120001729 gcvA b2808 2941650 2942567 reverse DNA-binding transcriptional dual regulator GcvA [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IDA-BINDING-OF-PURIFIED-PROTEINS|S|Binding of purified proteins],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 27718375,7665470,8188587,8375392, Strong b2808 ECK120002579 gcvB b4443 2942696 2942901 forward small regulatory RNA GcvB [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 10972807,11448770,12069726,17264113,18312576,19118351,19221499,22020646,23316042,24391513,25358737,27588604,29905843,30447071,31553492,33169170,34065855, Weak b4443 ECK120004016 ygdI b2809 2942918 2943145 reverse DUF903 domain-containing lipoprotein YgdI 15174130,32053772, b2809 ECK120004017 csdA b2810 2943337 2944542 forward cysteine sulfinate desulfinase b2810 ECK120004018 csdE b2811 2944542 2944985 forward sulfur acceptor protein CsdE b2811 ECK120004019 tcdA b2812 2945036 2945842 reverse tRNA threonylcarbamoyladenosine dehydratase b2812 ECK120004020 mltA b2813 2946081 2947178 reverse membrane-bound lytic murein transglycosylase A 11139297,12399477,1356966,15039577,15793119,15858272,32053772, b2813 ECK120002504 metZ b2814 2947387 2947463 forward tRNA-initiator Met(CAU) [AS-TAS|W|Traceable author statement] 25246575,27698115,7033244, Weak b2814 ECK120002559 metW b2815 2947497 2947573 forward tRNA-initiator Met(CAU) [AS-TAS|W|Traceable author statement] 25246575,27698115,7033244, Weak b2815 ECK120002502 metV b2816 2947607 2947683 forward tRNA-initiator Met(CAU) [AS-TAS|W|Traceable author statement] 2112406,25246575,27698115,7033244, Weak b2816 ECK120004021 amiC b2817 2947757 2949010 reverse -acetylmuramoyl-L-alanine amidase C 1102308,6133749, b2817 ECK120000059 argA b2818 2949242 2950573 forward N-acetylglutamate synthase b2818 ECK120000817 recD b2819 2950635 2952461 reverse exodeoxyribonuclease V subunit RecD 16452142,3015881, b2819 ECK120000815 recB b2820 2952461 2956003 reverse exodeoxyribonuclease V subunit RecB 31683605,33382157, b2820 ECK120000777 ptrA b2821 2955996 2958884 reverse protease 3 7674955,7674956, b2821 ECK120000816 recC b2822 2959060 2962428 reverse exodeoxyribonuclease V subunit RecC 12754220,3155726,33382157, b2822 ECK120001137 ppdC b2823 2962441 2962764 reverse prepilin-type N-terminal cleavage/methylation domain-containing protein PpdC 23006128, b2823 ECK120001138 ygdB b2824 2962749 2963156 reverse DUF2509 domain-containing protein YgdB 23006128, b2824 ECK120001139 ppdB b2825 2963153 2963716 reverse prepilin-type N-terminal cleavage/methylation domain-containing protein PpdB 23006128, b2825 ECK120001987 ppdA b2826 2963707 2964177 reverse prepilin-type N-terminal cleavage/methylation domain-containing protein PpdA 23006128, b2826 ECK120000991 thyA b2827 2964361 2965155 reverse thymidylate synthase b2827 ECK120002030 lgt b2828 2965162 2966037 reverse phosphatidylglycerol—prolipoprotein diacylglyceryl transferase 26335199,33875545,341153,7048314,7592473,8051048, b2828 ECK120002077 ptsP b2829 2966188 2968434 reverse phosphoenolpyruvate-protein phosphotransferase PtsP 30800588,33717488, b2829 ECK120004022 rppH b2830 2968447 2968977 reverse RNA pyrophosphohydrolase 19636968,26323881,26627477,30788220,31173659,31178354,31612599,32779574,32954454,33464822, b2830 ECK120030084 ygdT b4610 2969330 2969476 reverse hypothetical protein YgdT b4610 ECK120000617 mutH b2831 2969662 2970351 forward DNA mismatch repair protein MutH 1601880,2824465,9393714,9482749, b2831 ECK120004023 ygdQ b2832 2970420 2971133 forward PF03741 family inner membrane protein YgdQ b2832 ECK120004024 ygdR b2833 2971271 2971489 forward DUF903 domain-containing lipoprotein YgdR 32053772, b2833 ECK120004025 tas b2834 2971597 2972637 forward putative NADP(H)-dependent aldo-keto reductase Tas [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 11470487,24516157,9560382, Weak b2834 ECK120002304 lplT b2835 2972669 2973862 reverse lysophospholipid transporter 30790256, b2835 ECK120001622 aas b2836 2973855 2976014 reverse fused 2-acylglycerophospho-ethanolamine acyltransferase/acyl-acyl carrier protein synthetase b2836 ECK120002580 omrA b4444 2976102 2976189 reverse small regulatory RNA OmrA [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 11448770,11553332,16359331,18953042,20407422,22040174,32133913, Weak b4444 ECK120002593 omrB b4445 2976304 2976385 reverse small regulatory RNA OmrB [EXP-IMP|W|Inferred from mutant phenotype] 16359331,18953042, Weak b4445 ECK120000357 galR b2837 2976599 2977630 forward DNA-binding transcriptional dual regulator GalR [EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IPI|W|Inferred from physical interaction],[EXP-IMP|W|Inferred from mutant phenotype] 12169637,15533432,15807530,17630975,6283521,6350601,7934815,8188660,9218807,9325090, Weak b2837 ECK120000542 lysA b2838 2977637 2978899 reverse diaminopimelate decarboxylase b2838 ECK120000544 lysR b2839 2979021 2979956 forward DNA-binding transcriptional dual regulator LysR [EXP|W|Inferred from experiment] 6350602, Weak b2839 ECK120001140 ygeA b2840 2979943 2980635 reverse amino acid racemase YgeA b2840 ECK120000052 araE b2841 2980764 2982182 reverse arabinose:H symporter 2836407, b2841 ECK120002229 kduD b2842 2982497 2983258 reverse putative 2-keto-3-deoxy-D-gluconate dehydrogenase b2842 ECK120004026 kduI b2843 2983288 2984124 reverse 5-dehydro-4-deoxy-D-glucuronate isomerase b2843 ECK120004027 yqeF b2844 2984411 2985592 reverse putative acyltransferase [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 16397293,21832992, Weak b2844 ECK120004028 yqeG b2845 2985847 2987076 forward putative transporter YqeG 31438868, b2845 ECK120004029 yqeH b2846 2987536 2988168 forward putative LuxR family transcriptional regulator YqeH b2846 ECK120004030 yqeI b2847 2988502 2989311 forward putative transcriptional regulator YqeI [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15556475, Weak b2847 ECK120004031 yqeJ b2848 2989304 2989786 forward protein YqeJ b2848 ECK120048862 yqeL b4683 2989819 2989899 reverse uncharacterized protein YqeL b4683 ECK120004032 yqeK b2849 2989935 2990360 reverse protein YqeK b2849 ECK120004033 ygeF b2850 2990554 2991043 forward protein YgeF b2850 ECK120004034 ygeG b2851 2991268 2991759 forward TPR repeat-containing putative chaperone YgeG b2851 ECK120004035 ygeH b2852 2992094 2993470 forward putative transcriptional regulator YgeH [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15556475,25343852, Weak b2852 ECK120004036 ygeI b2853 2993638 2993856 forward protein YgeI b2853 ECK120004037 pbl b2854 2993939 2994441 forward transglycosylase domain-containing protein Pbl b2854 ECK120004038 ygeK b2855 2994460 2994903 reverse putative DNA-binding transcriptional regulator YgeK [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b2855 ECK120004039 ygeL b2856 2994937 2995092 reverse protein YgeL b2856 ECK120004041 ygeN b2858 2995314 2996020 reverse putative type III secretion system protein YgeN b2857,b2858 ECK120004042 ygeO b2859 2995962 2996360 reverse putative uncharacterized protein YgeO b2859 ECK120023920 insCD4 2996372 2997600 reverse IS2 element transposase InsAB' ECK120004043 insD4 b2860 2996372 2997277 reverse IS2 insertion element protein InsB b2860 ECK120004044 insC4 b2861 2997235 2997600 reverse IS2 insertion element repressor InsA b2861 ECK120004045 ygeP b2862 2997689 2997988 reverse protein YgeP b2862 ECK120004046 ygeQ b2863 2998034 2998828 reverse putative lipoprotein YgeQ b2863 ECK120002479 glyU b2864 2998984 2999057 reverse tRNA-Gly(CCC) b2864 ECK120004047 actS b2865 2999136 2999891 reverse amidase activator [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 32053772,33660879, Weak b2865 ECK120004048 xdhA b2866 3000345 3002603 forward putative xanthine dehydrogenase molybdenum-binding subunit XdhA 10986234,11574054, b2866 ECK120004049 xdhB b2867 3002614 3003492 forward putative xanthine dehydrogenase FAD-binding subunit XdhB 10986234,11574054, b2867 ECK120004050 xdhC b2868 3003489 3003968 forward putative xanthine dehydrogenase iron-sulfur-binding subunit XdhC 10986234,11574054, b2868 ECK120004051 ygeV b2869 3004008 3005786 reverse putative σ-dependent transcriptional regulator YgeV [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 10734204,15556475, Weak b2869 ECK120004052 ygeW b2870 3006262 3007452 forward putative carbamoyltransferase YgeW b2870 ECK120004053 ygeX b2871 3007510 3008706 forward 2,3-diaminopropionate ammonia-lyase 22904288, b2871 ECK120004054 ygeY b2872 3008764 3009975 forward putative peptidase YgeY 24391520, b2872 ECK120004055 hyuA b2873 3010028 3011413 forward phenylhydantoinase b2873 ECK120004056 yqeA b2874 3011461 3012393 forward putative amino acid kinase YqeA b2874 ECK120004057 yqeB b2875 3012614 3014239 reverse XdhC-CoxI family protein YqeB b2875 ECK120004058 yqeC b2876 3014287 3015057 reverse uncharacterized protein YqeC b2876 ECK120004059 mocA b2877 3015160 3015738 forward molybdenum cofactor cytidylyltransferase b2877 ECK120004060 ygfK b2878 3016060 3019158 forward putative oxidoreductase, Fe-S subunit b2878 ECK120004061 ssnA b2879 3019161 3020489 forward putative aminohydrolase SsnA [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10986234, Weak b2879 ECK120004062 ygfM b2880 3020540 3021319 forward putative oxidoreductase b2880 ECK120004063 xdhD b2881 3021316 3024186 forward fused putative xanthine/hypoxanthine oxidase: molybdopterin-binding subunit and Fe-S binding subunit 10986234,22094925, b2881 ECK120004064 xanQ b2882 3024351 3025751 forward xanthine:H symporter XanQ 16096268,34710398, b2882 ECK120004065 guaD b2883 3025766 3027085 forward guanine deaminase b2883 ECK120004066 ghxQ b4464 3027121 3028488 forward guanine/hypoxanthine transporter GhxQ 14526028,17416652,31438868, b2884,b2885,b4464 ECK120004067 ygfS b2886 3028524 3029012 reverse putative electron transport protein YgfS b2886 ECK120004068 ygfT b2887 3029012 3030931 reverse putative oxidoreductase YgfT b2887 ECK120004069 uacT b2888 3031367 3032815 forward urate:H symporter 10986234,31438868, b2888 ECK120048868 yqfG b4684 3032817 3032942 forward uncharacterized protein YqfG b4684 ECK125276531 yqfH b4753 3032939 3033010 reverse protein YqfH b4753 ECK120004070 idi b2889 3033065 3033613 forward isopentenyl-diphosphate Δ-isomerase 9603997, b2889 ECK120000545 lysS b2890 3033657 3035174 reverse lysine—tRNA ligase 10369781,10623523,16672269,16855227,1709878,17384228,17889423,2001999,2188953,2554306,2560134,2668951,318645,328487,3312173,345082,3881393,4552089,4552090,6373723,779846,779847,786844,7896714,805427,807389,8152,8166708, b2890 ECK120000753 prfB b2891 3035184 3036282 reverse peptide chain release factor RF2 [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 19092806, Weak b2891 ECK120000821 recJ b2892 3036373 3038106 reverse ssDNA-specific exonuclease RecJ 10224241,10368783,10420269,12718760,12840109,15687199,16135232,16452142,16702415,16816175,16904387,17526695,17932052,17965170,1832022,18407965,18445487,1911953,1917853,19451222,1987126,20304994,2086342,21938951,22496668,22957093,2536671,2556327,2656639,2664459,2670665,26967458,2823066,2841294,2841571,2842223,2848620,2984175,2993230,3065139,31683605,3298213,3329215,3526390,4587405,7517004,7961480,8132450,8344265,8407784,9618512,9791113,9862197, b2892 ECK120001059 dsbC b2893 3038112 3038822 reverse protein disulfide isomerase DsbC [EXP-IDA|W|Inferred from direct assay] 10234837,10391895,10930424,11042167,11208797,12498799,14729690,15122895,15220477,15388920,16087673,16233282,16280324,16321931,17372350,18325532,18782764,19581640,19906178,19968787,8168497,8645242,9003292,9099671,9254601,9454567, Weak b2893 ECK120001060 xerD b2894 3038847 3039743 reverse site-specific recombinase [EXP-IMP|W|Inferred from mutant phenotype] 1987126,8402918, Weak b2894 ECK120002360 fldB b2895 3039855 3040376 forward flavodoxin 2 4927832, b2895 ECK120004071 ygfX b2896 3040416 3040823 reverse protein YgfX [EXP-IDA|W|Inferred from direct assay] 22239607, Weak b2896 ECK120004072 sdhE b2897 3040804 3041070 reverse FAD assembly factor [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IPI|W|Inferred from physical interaction],[EXP-IGI|W|Inferred from genetic interaction] 22239607,22474332,26644464, Weak b2897 ECK120004073 ygfZ b2898 3041313 3042293 forward folate-binding protein [EXP-IGI|W|Inferred from genetic interaction] 16359333,22081392,34070637, Weak b2898 ECK120004074 yqfA b2899 3042489 3043148 reverse hemolysin-III family protein YqfA b2899 ECK120004075 yqfB b2900 3043312 3043623 reverse -acetylcytidine amidohydrolase b2900 ECK120002697 bglA b2901 3043662 3045101 forward 6-phospho-β-glucosidase A 11420377,1999380,2254239,4870648,5335892,5335893, b2901 ECK120004076 ygfF b2902 3045158 3045901 reverse putative oxidoreductase YgfF b2902 ECK120001744 gcvP b2903 3046168 3049041 reverse glycine decarboxylase b2903 ECK120000364 gcvH b2904 3049160 3049549 reverse glycine cleavage system H protein [EXP|W|Inferred from experiment] 1655709,3108237,6358793,8444795, Weak b2904 ECK120001406 gcvT b2905 3049573 3050667 reverse aminomethyltransferase b2905 ECK125276510 yqfI b4754 3050958 3051041 forward protein YqfI b4754 ECK120001304 ubiI b2906 3051115 3052317 reverse 2-octaprenylphenol 6-hydroxylase b2906 ECK120001295 ubiH b2907 3052340 3053518 reverse 2-octaprenyl-6-methoxyphenol 4-hydroxylase 365223, b2907 ECK120000689 pepP b2908 3053515 3054840 reverse Xaa-Pro aminopeptidase b2908 ECK120001294 ygfB b2909 3054866 3055444 reverse PF03695 family protein YgfB 1339425, b2909 ECK120002417 zapA b2910 3055612 3055941 forward cell division protein ZapA 12900028,23708427, b2910 ECK120002541 ssrS b2911 3055983 3056165 forward 6S RNA [EXP-IDA|W|Inferred from direct assay] 10892648,1098044,29686109,4570237,4929322,6231216, Weak b2911 ECK120001141 fau b2912 3056241 3056789 forward putative 5-formyltetrahydrofolate cyclo-ligase 21538139, b2912 ECK120002597 sibC b4446 3056851 3056991 forward small regulatory RNA antitoxin SibC [EXP-IMP|W|Inferred from mutant phenotype] 18710431,26020590, Weak b4446 ECK120035073 ibsC b4665 3056890 3056949 reverse toxic peptide IbsC [EXP-IMP|W|Inferred from mutant phenotype] 18710431,19090519, Weak b4665 ECK120000933 serA b2913 3057178 3058410 reverse phosphoglycerate dehydrogenase 19924905,22547037,23563322,26416585,28853268,3017965, b2913 ECK120001407 rpiA b2914 3058666 3059325 reverse ribose-5-phosphate isomerase A 11101318,17112383, b2914 ECK120004077 yqfE b2915 3059381 3059611 reverse putative protein YqfE b2915 ECK120000483 argP b2916 3059753 3060646 forward DNA-binding transcriptional dual regulator ArgP 2034653,8825783,9819053, b2916 ECK120001408 scpA b2917 3060850 3062994 forward methylmalonyl-CoA mutase b2917 ECK120001409 argK b2918 3062987 3063982 forward methylmalonyl-CoA mutase-interacting GTPase YgfD b2918 ECK120004078 scpB b2919 3063993 3064778 forward methylmalonyl-CoA decarboxylase b2919 ECK120004079 scpC b2920 3064802 3066280 forward propionyl-CoA:succinate CoA transferase b2920 ECK120004080 ygfI b2921 3066277 3067173 reverse putative DNA-binding transcriptional regulator YgfI [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b2921 ECK125135301 och5 3067187 3067344 forward small regulatory RNA Och5 [EXP-IMP|W|Inferred from mutant phenotype] 26469694, Weak ECK120001220 yggE b2922 3067340 3068080 reverse DUF541 domain-containing protein YggE 22210207,23097194, b2922 ECK120001142 argO b2923 3068173 3068808 reverse L-arginine exporter 22904281, b2923 ECK120001143 mscS b2924 3068947 3069807 reverse small conductance mechanosensitive channel MscS 11960017,12015316,12046893,12374733,12446894,12505982,12561825,12620208,15277576,15339798,15665126,15665866,15702067,15834558,16861270,17277184,17718516,18037888,18755969,18755978,19383606,20037156,20978126,21767486,23012406,23339071,23842527,2436228,24559986,24778428,25958301,26340270,26551077,31173776,31291591,31783284,31880537,33568813, b2924 ECK120000276 fbaA b2925 3070165 3071244 reverse fructose-bisphosphate aldolase class II 2546007, b2925 ECK120000695 pgk b2926 3071459 3072622 reverse phosphoglycerate kinase 2546007,33221881,34488574,34608152, b2926 ECK120000361 epd b2927 3072672 3073691 reverse D-erythrose-4-phosphate dehydrogenase 2546007,7751290, b2927 ECK120001144 yggC b2928 3073976 3074689 reverse P-loop NTPase domain-containing protein YggC b2928 ECK120001145 fumE b2929 3074686 3075195 reverse fumarase E [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15556475, Weak b2929 ECK120001221 yggF b2930 3075217 3076182 reverse fructose 1,6-bisphosphatase YggF b2930 ECK120004081 yggP b4465 3076179 3077456 reverse putative zinc-binding dehydrogenase YggP b2931,b2932,b4465 ECK120001726 cmtA b2933 3077471 3078859 reverse mannitol-specific PTS enzyme IICB component CmtA b2933 ECK120001725 cmtB b2934 3078887 3079330 reverse mannitol-specific PTS enzyme IIA component CmtB b2934 ECK120001391 tktA b2935 3079644 3081635 reverse transketolase 1 11101318,1537815,22821820,24984289,27657847,28640743,30009844,31281927,32046235,32139871,32839604,33001250,8241274,8958067,8958111,9147449,9546650, b2935 ECK120001264 loiP b2936 3081913 3082671 forward metalloprotease LoiP 32053772, b2936 ECK120000949 speB b2937 3082877 3083797 reverse agmatinase 10075412,10931887,15369817,19493013,19542271,2153656,2203728,2440022,3081491,31186003,32057730,3514574,4550506,4552550,4579867,5330264,6353147,6392022,6413821, b2937 ECK120000948 speA b2938 3083935 3085911 reverse biosynthetic arginine decarboxylase 10075412,10439394,1310091,15299455,16541190,16747177,2198270,2203728,2440022,29123334,3514574,4569404,4891156,4908781,6351053,6353147,6353148,6392022,6413821,6754041,6788079,6800359,9765988, b2938 ECK120004082 yqgB b2939 3085920 3086051 reverse acid stress response protein YqgB [EXP-IMP|W|Inferred from mutant phenotype] 19734312, Weak b2939 ECK125286397 yqgG b4784 3086145 3086288 reverse protein YqgG b4784 ECK120004083 yqgC b2940 3086187 3086402 forward protein YqgC b2940 ECK120004084 yqgD b2941 3086399 3086650 reverse DUF2684 domain-containing protein YqgD b2941 ECK120000582 metK b2942 3086706 3087860 forward methionine adenosyltransferase b2942 ECK120002048 galP b2943 3088284 3089678 forward galactose:H symporter b2943 ECK120002025 yggI b2944 3089755 3090252 forward protein YggI b2944 ECK120001307 endA b2945 3090347 3091054 forward DNA-specific endonuclease I 10080932,1092660,12951767,14255756,15767782,1631242,18438778,194597,195932,22992433,371681,4287760,4911845,4911846,4955462,4991605,7789817,7980923,800985,8113204,8479929, b2945 ECK120002234 rsmE b2946 3091134 3091865 forward 16S rRNA mU1498 methyltransferase 18288206,20477873,22925577, b2946 ECK120000412 gshB b2947 3091878 3092828 forward glutathione synthetase b2947 ECK120004085 yqgE b2948 3092937 3093500 forward DUF179 domain-containing protein YqgE 27527105, b2948 ECK120004086 yqgF b2949 3093500 3093916 forward ribonuclease H-like domain-containing nuclease [EXP-IDA|W|Inferred from direct assay],[EXP-IGI|W|Inferred from genetic interaction] 15353568,22353788,25545592,26817626,27527105,30566952, Weak b2949 ECK120004087 yggR b2950 3094100 3095080 reverse Type II/IV secretion system family protein b2950 ECK120004088 yggS b2951 3095098 3095802 forward PLP homeostasis protein b2951 ECK120004089 yggT b2952 3095820 3096386 forward uncharacterized protein YggT [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation] 19966467,31438868, Strong b2952 ECK120004090 yggU b2953 3096383 3096673 forward DUF167 domain-containing protein YggU b2953 ECK120004091 rdgB b2954 3096681 3097274 forward dITP/XTP pyrophosphatase b2954 ECK120004092 hemW b2955 3097267 3098403 forward heme chaperone HemW b2955 ECK120002363 yggM b2956 3098558 3099565 reverse DUF1202 domain-containing protein YggM b2956 ECK120000042 ansB b2957 3099682 3100728 reverse L-asparaginase 2 b2957 ECK120002364 yggN b2958 3100904 3101623 reverse DUF2884 domain-containing protein YggN [EXP-IMP|W|Inferred from mutant phenotype] 11274153,14731270, Weak b2958 ECK120002296 yggL b2959 3101807 3102133 reverse putative ribosome assembly factor YggL 23228329,32813020, b2959 ECK120001713 trmB b2960 3102133 3102852 reverse tRNA mG46 methyltransferase b2960 ECK120000620 mutY b2961 3103013 3104065 forward adenine DNA glycosylase 10350454,10569924,10722679,11101292,11960995,12534293,28723094,30617079,33202125,8663135,8798653,8988002,9778350, b2961 ECK120004093 yggX b2962 3104093 3104368 forward putative Fe-trafficking protein [EXP-IMP|W|Inferred from mutant phenotype] 14594836, Weak b2962 ECK120004094 mltC b2963 3104433 3105512 forward membrane-bound lytic murein transglycosylase C 11139297,32053772, b2963 ECK120000657 nupG b2964 3105714 3106970 forward nucleoside:H symporter NupG 2115441,23256604,31438868,323246,32994326,4133184,4563236,4946509,6446715,773649,9529885, b2964 ECK120000950 speC b2965 3107020 3109155 reverse constitutive ornithine decarboxylase b2965 ECK125286408 yqgH b4785 3109317 3109400 reverse protein YqgH b4785 ECK120004095 yqgA b2966 3109553 3110260 forward DUF554 domain-containing protein YqgA b2966 ECK120002507 pheV b2967 3110366 3110441 forward tRNA-Phe(GAA) [AS-TAS|W|Traceable author statement] 7033244, Weak b2967 ECK120004096 yghD b2968 3110590 3111126 reverse putative type II secretion system M-type protein YghD b2968 ECK120004097 yghE b2969 3111128 3111988 reverse putative type II secretion system L-type protein YghE b2969 ECK125286420 yqhJ b4786 3111266 3111325 forward protein YqhJ 30837344, b4786 ECK120004098 yghF b2970 3112054 3113049 reverse putative type II secretion system C-type protein YghF 24391520, b2970 ECK120004099 yghG b2971 3113067 3113477 reverse lipoprotein YghG 32053772, b2971 ECK120004100 pppA b2972 3113543 3114352 reverse prepilin peptidase [EXP-IMP|W|Inferred from mutant phenotype] 24478067,24809621,9515702, Weak b2972 ECK120004101 yghJ b4466 3114550 3119112 reverse putative lipoprotein YghJ b2973,b2974,b4466 ECK120004102 glcA b2975 3119597 3121279 reverse glycolate/lactate:H symporter GlcA b2975 ECK120002622 C0719 3121358 3121579 forward ECK120002441 glcB b2976 3121634 3123805 reverse malate synthase G 15189138,16511237,17406304,19274445,20809933,21864568,22532128,23718231,24057411,26950748, b2976 ECK120004103 glcG b2977 3123827 3124231 reverse putative heme-binding protein GlcG 26950748, b2977 ECK120002572 glcF b4467 3124236 3125459 reverse glycolate dehydrogenase, putative iron-sulfur subunit 26950748,8606183, b2978,b4467 ECK120004104 glcE b4468 3125470 3126522 reverse glycolate dehydrogenase, putative FAD-binding subunit 26950748,8606183, b2978,b4468 ECK120004105 glcD b2979 3126522 3128021 reverse glycolate dehydrogenase, putative FAD-linked subunit 26272093,26950748,27252779,29392388,30987875, b2979 ECK120004106 glcC b2980 3128272 3129036 forward DNA-binding transcriptional dual regulator GlcC b2980 ECK120004107 yghO b2981 3129043 3130215 reverse putative DNA-binding transcriptional regulator YghO [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 10734204,14731270,15556475, Weak b2981 ECK120004108 insH9 b2982 3130214 3131194 forward IS transposase and trans-activator b2982 ECK120004109 yghQ b2983 3131341 3132408 reverse putative transport protein YghQ b2983 ECK120004110 yghR b2984 3132454 3133212 reverse putative ATP-binding protein YghR b2984 ECK120004111 yghS b2985 3133244 3133957 reverse putative ATP-binding protein YghS b2985 ECK120004112 yghT b2986 3134131 3134823 forward putative ATP-binding protein YghT b2986 ECK120002422 pitB b2987 3134872 3136371 reverse metal phosphate:H symporter PitB b2987 ECK120002421 gss b2988 3136663 3138522 reverse fused glutathionylspermidine amidase / glutathionylspermidine synthetase b2988 ECK120004113 yghU b2989 3138727 3139593 forward disulfide reductase / organic hydroperoxide reductase b2989 ECK120001739 hybG b2990 3139716 3139964 reverse hydrogenase maturation factor HybG [EXP-IMP|W|Inferred from mutant phenotype] 11292801,26170410,26364315,31611859,34934150, Weak b2990 ECK120001738 hybF b2991 3139977 3140318 reverse hydrogenase maturation protein HybF [EXP-IMP|W|Inferred from mutant phenotype] 12081959, Weak b2991 ECK120001737 hybE b2992 3140311 3140799 reverse hydrogenase 2-specific chaperone [EXP-IMP|W|Inferred from mutant phenotype] 15385959, Weak b2992 ECK120001736 hybD b2993 3140792 3141286 reverse hydrogenase 2 maturation protease 11847292,24884349,26170410,31611859,8021226, b2993 ECK120001735 hybC b2994 3141286 3142989 reverse hydrogenase 2 large subunit b2994 ECK120001734 hybB b2995 3142986 3144164 reverse hydrogenase 2 membrane subunit b2995 ECK120001733 hybA b2996 3144154 3145140 reverse hydrogenase 2 iron-sulfur protein b2996 ECK120004114 hybO b2997 3145143 3146261 reverse hydrogenase 2 small subunit b2997 ECK120004115 yghW b2998 3146450 3146737 reverse DUF2623 domain-containing protein YghW 23913318,27050393, b2998 ECK120004117 yghX b4658 3146856 3147691 reverse putative hydrolase fragment b2999,b3000,b4658 ECK125276519 yqhI b4755 3147597 3147740 reverse protein YqhI b4755 ECK120004118 gpr b3001 3147897 3148937 forward L-glyceraldehyde 3-phosphate reductase b3001 ECK120004119 yqhA b3002 3148977 3149471 reverse UPF0114 family protein YqhA b3002 ECK120001265 yghA b3003 3149662 3150546 forward NADP-dependent aldehyde reductase b3003 ECK120004120 Phantom Gene b3004 3150722 3150967 forward b3004 ECK120000266 exbD b3005 3150818 3151243 reverse Ton complex subunit ExbD 17927700,19627500,31932309, b3005 ECK120000265 exbB b3006 3151250 3151984 reverse Ton complex subunit ExbB 19627500,8100348,8316079, b3006 ECK120004121 Phantom Gene b3007 3151977 3152132 reverse b3007 ECK120000576 metC b3008 3152236 3153423 forward cystathionine β-lyase / L-cysteine desulfhydrase / alanine racemase b3008 ECK120001756 yghB b3009 3153563 3154222 forward DedA family protein YghB [EXP-IGI|W|Inferred from genetic interaction] 18456815,24277026, Weak b3009 ECK120004122 yqhC b3010 3154262 3155218 reverse DNA-binding transcriptional activator YqhC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10734204,15556475,20543070, Strong b3010 ECK120004123 yqhD b3011 3155355 3156518 forward NADPH-dependent aldehyde reductase YqhD 22538653,24885133,25063650,26438162,26476644,26660478,27535647,29842925,31867522,32653931,32683722, b3011 ECK120004124 dkgA b3012 3156623 3157450 forward methylglyoxal reductase DkgA b3012 ECK120004125 yqhG b3013 3157650 3158576 forward DUF3828 domain-containing protein YqhG b3013 ECK120004126 yqhH b3014 3158627 3158884 forward lipoprotein YqhH 32053772, b3014 ECK120004127 ygiQ b4469 3158927 3161146 reverse radical SAM superfamily protein YgiQ 24391520, b3015,b3016,b4469 ECK120001344 ftsP b3017 3161257 3162669 reverse cell division protein FtsP [EXP-IMP|W|Inferred from mutant phenotype] 12940994,14580344,17212781,17766410,17908913,22315217,22362773,23422074,32866331, Weak b3017 ECK120001345 plsC b3018 3162744 3163481 reverse 1-acylglycerol-3-phosphate -acyltransferase PlsC 15380559,1557036,17850764,2842295,28714993,3056107,6351928, b3018 ECK120000679 parC b3019 3163715 3165973 reverse DNA topoisomerase IV subunit A b3019 ECK120004128 ygiS b3020 3166111 3167718 reverse putative deoxycholate binding periplasmic protein [EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ] 25534751,31438868, Weak b3020 ECK120004129 mqsA b3021 3167851 3168246 reverse antitoxin of the MqsRA toxin-antitoxin system / DNA-binding transcriptional repressor MqsA [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 15556475,19690171,20105222, Strong b3021 ECK120004130 mqsR b3022 3168248 3168544 reverse mRNA interferase toxin MqsR [EXP-IDA|W|Inferred from direct assay] 19690171,24373067,25912447,26483762,26621053,26837570,28979246,31848281, Weak b3022 ECK120004131 ygiV b3023 3168749 3169231 reverse DNA-binding transcriptional repressor YgiV [EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ] 18309357, Weak b3023 ECK120004132 ygiW b3024 3169284 3169676 reverse BOF family protein YgiW [EXP-IMP|W|Inferred from mutant phenotype] 19919618, Weak b3024 ECK120004133 qseB b3025 3169828 3170487 forward DNA-binding transcriptional activator QseB [EXP|W|Inferred from experiment] 11929534,32979869, Weak b3025 ECK120002348 qseC b3026 3170484 3171833 forward sensor histidine kinase QseC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 11929534,12076823,12366850,15522865,23651393, Weak b3026 ECK120004134 ygiZ b3027 3171879 3172211 reverse DUF2645 domain-containing inner membrane protein YgiZ b3027 ECK120002346 mdaB b3028 3172530 3173111 forward NADPH:quinone oxidoreductase MdaB b3028 ECK120002347 ygiN b3029 3173142 3173456 forward putative quinol monooxygenase YgiN b3029 ECK120000680 parE b3030 3173504 3175396 reverse DNA topoisomerase IV subunit B b3030 ECK120004135 yqiA b3031 3175425 3176006 reverse esterase YqiA [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 15808744, Weak b3031 ECK120004136 cpdA b3032 3176006 3176833 reverse cAMP phosphodiesterase 22101045,25061041,8810311, b3032 ECK120004137 yqiB b3033 3176858 3177280 reverse DUF1249 domain-containing protein YqiB b3033 ECK120002344 nudF b3034 3177281 3177910 reverse ADP-sugar pyrophosphatase 15967507,23618128,26091008,29551348, b3034 ECK120000998 tolC b3035 3178115 3179596 forward outer membrane channel TolC b3035 ECK120001146 ygiA b3036 3179596 3179856 forward b3036 ECK120001147 ygiB b3037 3179744 3180415 forward DUF1190 domain-containing protein YgiB [EXP-IMP|W|Inferred from mutant phenotype] 14731270, Weak b3037 ECK120001148 ygiC b3038 3180421 3181581 forward putative acid—amine ligase YgiC b3038 ECK120001149 ygiD b3039 3181619 3182434 reverse 4,5-DOPA dioxygenase extradiol b3039 ECK120001150 zupT b3040 3182550 3183323 forward divalent metal ion transporter ZupT 11790762, b3040 ECK125276529 yqiD b4756 3183381 3183551 reverse protein YqiD b4756 ECK120000458 ribB b3041 3183813 3184466 reverse 3,4-dihydroxy-2-butanone-4-phosphate synthase 20400551,6315532, b3041 ECK120002646 sroG 3184570 3184718 reverse ECK120004138 ubiK b3042 3184840 3185130 forward ubiquinone biosynthesis accessory factor UbiK [EXP-IMP|W|Inferred from mutant phenotype] 23228329,28559279,34117231,9868784, Weak b3042 ECK120002231 ygiL b3043 3185414 3185965 forward putative fimbrial protein YgiL 20345943,21344461,23382825, b3043 ECK120004139 insC5 b3044 3186187 3186552 forward IS2 insertion element repressor InsA b3044 ECK120023921 insCD5 3186187 3187415 forward IS2 element transposase InsAB' ECK120004140 insD5 b3045 3186510 3187415 forward IS2 insertion element protein InsB b3045 ECK120004142 yqiH b3047 3189881 3190630 forward putative fimbrial chaperone YqiH [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 12192075,20345943,21344461,23382825, Weak b3047 ECK120004143 yqiI b3048 3190632 3191696 forward putative fimbrial protein YqiI [EXP-IMP|W|Inferred from mutant phenotype] 17846588,20345943,21344461,23382825, Weak b3048 ECK120001349 glgS b3049 3191739 3191939 reverse surface composition regulator [EXP-IMP|W|Inferred from mutant phenotype] 1324388,23128992,23537328, Weak b3049 ECK120004144 yqiJ b3050 3192208 3192837 forward DUF1449 domain-containing inner membrane protein YqiJ b3050 ECK120004145 yqiK b3051 3192864 3194525 forward flotillin family inner membrane protein YqiK b3051 ECK120002623 sibD b4447 3194721 3194865 reverse small RNA SibD [EXP-IMP|W|Inferred from mutant phenotype] 12069726,18710431,19350225, Weak b4447 ECK120035072 ibsD b4664 3194766 3194825 forward putative toxic peptide IbsD [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 18710431, Weak b4664 ECK120030085 sibE b4611 3195097 3195240 reverse small RNA SibE [EXP-IMP|W|Inferred from mutant phenotype] 18710431, Weak b4611 ECK120035071 ibsE b4666 3195141 3195200 forward toxic peptide IbsE [EXP-IMP|W|Inferred from mutant phenotype] 18710431, Weak b4666 ECK120004146 hldE b3052 3195320 3196753 reverse fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 1089628,1089629,15576807,23284671,23409840,23445125,23843301,24412338, b3052 ECK120001550 glnE b3053 3196801 3199641 reverse fused glutamine synthetase deadenylase/glutamine synthetase adenylyltransferase b3053 ECK120001551 ygiF b3054 3199664 3200965 reverse inorganic triphosphatase b3054 ECK120002289 ygiM b3055 3201207 3201827 forward putative signal transduction protein (SH3 domain) b3055 ECK120000132 cca b3056 3201891 3203129 forward fused CCA tRNA nucleotidyltransferase/phosphohydrolase 1093182,1104089,1104603,15625866,1700367,170083,2199760,2413440,3009457,30217865,4597452,4597453,4597454,4904396,6759088,8660309,9510330,9581565, b3056 ECK120001608 bacA b3057 3203310 3204131 reverse undecaprenyl pyrophosphate phosphatase 24068241,26335199,29559664, b3057 ECK120001616 folB b3058 3204221 3204589 reverse dihydroneopterin aldolase b3058 ECK120001617 plsY b3059 3204694 3205311 forward putative glycerol-3-phosphate acyltransferase 16949372, b3059 ECK120002359 ttdR b3060 3205324 3206256 reverse DNA-binding transcriptional activator Dan [EXP-IDA|W|Inferred from direct assay],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-PART-PURIFIED-PROTEIN-NH|W|Assay of protein partially-purified from its native host],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10734204,15556475,19661178,20156994, Strong b3060 ECK120001151 ttdA b3061 3206463 3207374 forward L(+)-tartrate dehydratase subunit α 16804186,3297921, b3061 ECK120001152 ttdB b3062 3207371 3207976 forward L(+)-tartrate dehydratase subunit β 18998556,3297921, b3062 ECK120002256 ttdT b3063 3208024 3209487 forward L-tartrate:succinate antiporter b3063 ECK120001153 tsaD b3064 3209530 3210543 reverse N-L-threonylcarbamoyladenine synthase, TsaD subunit 23323735,25038083, b3064 ECK120000911 rpsU b3065 3210781 3210996 forward 30S ribosomal subunit protein S21 b3065 ECK120000233 dnaG b3066 3211107 3212852 forward DNA primase b3066 ECK120000887 rpoD b3067 3213047 3214888 forward RNA polymerase sigma factor RpoD 14712643,4343249, b3067 ECK120002372 mug b3068 3214967 3215473 reverse stationary phase mismatch/uracil DNA glycosylase 11035036,16908222,26774489,30617079, b3068 ECK120002488 ileX b3069 3215598 3215673 forward tRNA-Ile(CAU) [AS-TAS|W|Traceable author statement] 7033244, Weak b3069 ECK120004147 nfeF b3070 3215727 3216491 reverse NADPH-dependent ferric-chelate reductase 24982304, b3070 ECK120004148 nfeR b3071 3216779 3217402 forward DNA-binding transcriptional repressor NfeR b3071 ECK120004149 aer b3072 3217556 3219076 reverse aerotaxis receptor [EXP-IMP|W|Inferred from mutant phenotype] 10547687,10811894,15175278,15466030,15489456,16430703,16672601,16672602,18203838,27803157,9380664,9643537, Weak b3072 ECK120004150 patA b3073 3219494 3220873 forward putrescine aminotransferase b3073 ECK120004151 ygjH b3074 3220915 3221247 reverse putative tRNA-binding protein YgjH b3074 ECK120000248 ebgR b3075 3221466 3222449 forward DNA-binding transcriptional repressor EbgR [EXP|W|Inferred from experiment] Weak b3075 ECK120000246 ebgA b3076 3222633 3225725 forward evolved β-D-galactosidase subunit α b3076 ECK120000247 ebgC b3077 3225722 3226171 forward DUF386 domain-containing evolved β-D-galactosidase subunit β b3077 ECK120002373 ygjI b3078 3226234 3227667 forward putative transporter YgjI [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 16397293,31438868, Weak b3078 ECK120004152 ygjJ b3079 3227801 3228871 forward protein YgjJ b3079 ECK120004153 ygjK b3080 3228888 3231239 forward glycoside hydrolase b3080 ECK120002681 fadH b3081 3231665 3233683 forward 2,4-dienoyl-CoA reductase 15344554,6355075,6759505,7047514,9346310, b3081 ECK120004154 higA b3082 3233728 3234144 reverse antitoxin/DNA-binding transcriptional repressor HigA b3082 ECK120004155 higB b3083 3234141 3234455 reverse ribosome-dependent mRNA interferase toxin HigB b3083 ECK120004156 rlmG b3084 3234739 3235875 reverse 23S rRNA mG1835 methyltransferase b3084 ECK120004157 ygjP b3085 3235960 3236463 forward putative metal-dependent hydrolase b3085 ECK120004158 ygjQ b3086 3236540 3237232 forward DUF218 domain-containing protein YgjQ b3086 ECK120004159 ygjR b3087 3237311 3238297 forward putative oxidoreductase YgjR b3087 ECK120002581 sraF b4448 3238374 3238561 forward b4448 ECK120004160 alx b3088 3238580 3239545 forward putative membrane-bound redox modulator Alx 25794619, b3088 ECK120002374 sstT b3089 3239944 3241188 forward serine/threonine:Na symporter b3089 ECK120004161 ygjV b3090 3241193 3241744 reverse inner membrane protein [EXP|W|Inferred from experiment] 11574054,11867724, Weak b3090 ECK120002375 uxaA b3091 3241827 3243314 reverse D-altronate dehydratase b3091 ECK120004451 uxaC b3092 3243329 3244741 reverse D-glucoronate/D-galacturonate isomerase 4594010, b3092 ECK120002376 exuT b3093 3245224 3246522 forward hexuronate transporter b3093 ECK120002377 exuR b3094 3246652 3247428 forward DNA-binding transcriptional repressor ExuR [EXP|W|Inferred from experiment] 6357945, Weak b3094 ECK125286395 yqiM b4787 3247668 3247751 forward protein YqiM b4787 ECK120004162 yqjA b3095 3247773 3248435 forward DedA family protein YqjA [EXP-IGI|W|Inferred from genetic interaction] 24277026,26774489, Weak b3095 ECK120004163 mzrA b3096 3248439 3248822 forward modulator protein MzrA [EXP-IEP|W|Inferred from expression pattern] 19432797, Weak b3096 ECK120004164 yqjC b3097 3248969 3249337 forward DUF1090 domain-containing protein YqjC b3097 ECK120004165 yqjD b3098 3249375 3249680 forward ribosome- and membrane-associated DUF883 domain-containing protein YqjD [EXP-IMP|W|Inferred from mutant phenotype] 22661687,28738827,34644400, Weak b3098 ECK120004166 yqjE b3099 3249683 3250087 forward inner membrane protein YqjE b3099 ECK120004167 yqjK b3100 3250077 3250376 forward PF13997 family protein YqjK b3100 ECK120004168 yqjF b3101 3250562 3250954 forward DoxX family protein 25981994, b3101 ECK120004169 yqjG b3102 3251024 3252010 forward glutathionyl-hydroquinone reductase YqjG b3102 ECK120004170 yhaH b3103 3252304 3252669 forward putative inner membrane protein b3103 ECK120004171 yhaI b3104 3252911 3253267 forward putative inner membrane protein b3104 ECK120004172 yhaJ b3105 3253318 3254214 reverse DNA-binding transcriptional activator YhaJ [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10734204,15556475,27713734, Strong b3105 ECK120004173 yhaK b3106 3254319 3255020 forward bicupin-related protein b3106 ECK120004174 yhaL b3107 3255043 3255207 forward uncharacterized protein YhaL b3107 ECK120004175 cyuA b4470 3255341 3256651 reverse putative L-cysteine desulfidase CyuA b3108,b3109,b4470 ECK120002378 cyuP b3110 3256679 3258010 reverse cysteine detoxification protein CyuP b3110 ECK120004176 tdcG b4471 3258285 3259649 reverse L-serine deaminase III b3111,b3112,b4471 ECK120004177 tdcF b3113 3259721 3260110 reverse putative enamine/imine deaminase b3113 ECK120004178 tdcE b3114 3260124 3262418 reverse 2-ketobutyrate formate-lyase/pyruvate formate-lyase 4 b3114 ECK120001154 tdcD b3115 3262452 3263660 reverse propionate kinase b3115 ECK120000980 tdcC b3116 3263686 3265017 reverse threonine/serine:H symporter b3116 ECK120000979 tdcB b3117 3265039 3266028 reverse catabolic threonine dehydratase b3117 ECK120000978 tdcA b3118 3266127 3267065 reverse DNA-binding transcriptional activator TdcA [EXP|W|Inferred from experiment] 2660107,3003533,7928991,8413189,8413267, Weak b3118 ECK120000981 tdcR b3119 3267380 3267598 forward DNA-binding transcriptional activator TdcR [EXP|W|Inferred from experiment] 2573820,2660107,7928991, Weak b3119 ECK120001155 yhaB b3120 3267854 3268393 forward protein YhaB b3120 ECK120001156 yhaC b3121 3268415 3269602 forward uncharacterized protein YhaC b3121 ECK120002511 rnpB b3123 3270216 3270592 reverse RNase P catalytic RNA component [EXP-IDA|W|Inferred from direct assay] 6197186, Weak b3123 ECK120001157 garK b3124 3270625 3271770 reverse glycerate 2-kinase 1 b3124 ECK120001158 garR b3125 3271867 3272751 reverse tartronate semialdehyde reductase b3125 ECK120000014 garL b3126 3272787 3273557 reverse α-dehydro-β-deoxy--glucarate aldolase b3126 ECK120002379 garP b3127 3273573 3274907 reverse galactarate/D-glucarate transporter GarP b3127 ECK120002315 garD b3128 3275282 3276853 forward 10762278, b3128 ECK120000944 prlF b3129 3277002 3277337 forward antitoxin PrlF [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 17706670, Weak b3129 ECK120004179 yhaV b3130 3277337 3277801 forward ribosome-dependent mRNA interferase toxin YhaV 15939023, b3130 ECK120004180 agaR b3131 3277856 3278665 reverse DNA-binding transcriptional repressor AgaR [EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 14731281, Weak b3131 ECK120004181 kbaZ b3132 3278914 3280194 forward putative tagatose-1,6-bisphosphate aldolase 1 chaperone [EXP-IMP|W|Inferred from mutant phenotype] 11976750, Weak b3132 ECK120004182 agaV b3133 3280217 3280690 forward -acetyl-D-galactosamine specific PTS enzyme IIB component b3133 ECK120004183 agaW b3134 3280701 3281102 forward -acetyl-D-galactosamine specific PTS truncated enzyme IIC component 8932697, b3134 ECK120002380 agaA b3135 3281122 3281625 forward putative truncated N-acetylgalactosamine-6-phosphate deacetylase [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 12234664,8932697, Weak b3135 ECK120004184 agaS b3136 3281976 3283130 forward putative galactosamine-6-phosphate deaminase/isomerase 8932697,9697096, b3136 ECK120002381 kbaY b3137 3283143 3284003 forward tagatose-1,6-bisphosphate aldolase 1 b3137 ECK120002382 agaB b3138 3284170 3284646 forward galactosamine-specific PTS enzyme IIB component 8932697, b3138 ECK120002383 agaC b3139 3284685 3285488 forward galactosamine-specific PTS enzyme IIC component 8932697, b3139 ECK120004185 agaD b3140 3285478 3286269 forward galactosamine-specific PTS enzyme IID component 8932697, b3140 ECK120004186 agaI b3141 3286270 3287025 forward putative deaminase AgaI b3141 ECK120004187 yraH b3142 3287426 3288010 forward putative fimbrial protein YraH [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825,24391520, Weak b3142 ECK120004188 yraI b3143 3288090 3288785 forward putative fimbrial chaperone YraI [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 12192075,20345943,21344461,23382825,24391520, Weak b3143 ECK120004189 yraJ b3144 3288814 3291330 forward putative fimbrial usher protein YraJ [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825, Weak b3144 ECK120004190 yraK b3145 3291341 3292432 forward putative fimbrial adhesin YraK [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 20345943,21344461,23382825,32053772, Weak b3145 ECK120004191 rsmI b3146 3292475 3293335 reverse 16S rRNA 2'--ribose C1402 methyltransferase b3146 ECK120004192 lpoA b3147 3293400 3295436 forward outer membrane lipoprotein - activator of MrcA activity [EXP-IGI|W|Inferred from genetic interaction] 21183073,21183074,32053772, Weak b3147 ECK120004193 yraN b3148 3295394 3295789 forward PF02021 family protein YraN b3148 ECK120002384 diaA b3149 3295809 3296399 forward DnaA initiator-associating protein DiaA 17683397,18502852,19546317,21354425, b3149 ECK120004194 dolP b3150 3296409 3296984 forward division and outer membrane stress-associated lipid-binding lipoprotein 29176613,31364989,32053772,33847565, b3150 ECK120004195 yraQ b3151 3297098 3298138 reverse permease family protein YraQ 31438868, b3151 ECK120004196 yraR b3152 3298211 3298846 reverse putative nucleoside-diphosphate-sugar epimerase b3152 ECK120004197 yhbO b3153 3298974 3299492 forward protein/nucleic acid deglycase 2 [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 15716429,17933887,29842925, Weak b3153 ECK120004198 yhbP b3154 3299472 3299915 reverse putative FMN binding protein YhbP b3154 ECK120004199 yhbQ b3155 3299966 3300268 forward DNA damage response nuclease YhbQ b3155 ECK120004200 yhbS b3156 3300255 3300758 reverse putative -acetyltransferase YhbS b3156 ECK120004201 ubiT b3157 3300752 3301276 reverse anaerobic ubiquinone biosynthesis accessory factor UbiT [EXP-IMP|W|Inferred from mutant phenotype] 31289180, Weak b3157 ECK120004202 ubiU b3158 3301485 3302480 forward ubiquinone biosynthesis protein UbiU [EXP-IMP|W|Inferred from mutant phenotype] 31289180, Weak b3158 ECK120004203 ubiV b3159 3302489 3303367 forward ubiquinone biosynthesis protein UbiV [EXP-IMP|W|Inferred from mutant phenotype] 31289180, Weak b3159 ECK120004204 yhbW b3160 3303448 3304455 forward putative luciferase-like monooxygenase YhbW b3160 ECK120000610 mtr b3161 3304573 3305817 reverse tryptophan:H symporter Mtr b3161 ECK120000209 deaD b3162 3305971 3307860 reverse ATP-dependent RNA helicase DeaD b3162 ECK120048863 yrbN b4685 3307853 3307933 reverse uncharacterized protein YrbN b4685 ECK120002239 nlpI b3163 3308040 3308924 reverse lipoprotein NlpI b3163 ECK120000734 pnp b3164 3309033 3311168 reverse polynucleotide phosphorylase 16855227, b3164 ECK120002582 sraG b4449 3311183 3311398 forward small regulatory RNA SraG [EXP-IMP|W|Inferred from mutant phenotype] 11448770,27495318, Weak b4449 ECK120000905 rpsO b3165 3311415 3311684 reverse 30S ribosomal subunit protein S15 10376881,108264,11341947,11985624,12761296,1329024,15148358,15212951,16245373,16272117,18784650,19696352,21030658,22654657,236511,2413345,24339747,2581817,2582234,2689654,2849753,3087780,3126824,3297162,330222,330244,336508,344064,349351,351619,3541786,359353,371684,378264,380655,385343,388420,3908910,398003,407081,4579428,4587209,4592687,4912319,6159923,6200766,6209548,6290330,6306257,6354253,6371250,6382163,6394953,6752883,6759875,6995826,7024914,7040690,776686,782519,794830,796677,799248,9004854,9281425, b3165 ECK120001159 truB b3166 3311833 3312777 reverse tRNA pseudouridine synthase 15469254,21142053,21744792,21953190,6805514,8710514,8871555, b3166 ECK120001160 rbfA b3167 3312777 3313178 reverse 30S ribosome binding factor [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 23611982,25904134,27382067,28396444,30219894,31728529,9422595, Weak b3167 ECK120000498 infB b3168 3313342 3316014 reverse translation initiation factor IF-2β' [EXP-IDA|W|Inferred from direct assay] 10748005,1100407,1106767,11120350,11497435,12718519,14698286,1702020,1720674,17913632,18318122,19366171,2125480,217406,21801766,2207173,22411911,23536416,2444251,2448483,24794712,25308340,2684975,2695390,28914580,30904393,320048,3533628,359327,393258,4197131,4314905,4562740,4569079,4872321,4876939,6096856,6214789,6306257,6340723,6349681,6799502,6989597,6990978,6997046,7538134,782882,805131,826536,8483930,8608135,8798391,8999877,9428651,9698545,9826553, b3168 ECK120000498 infB b3168 3313342 3316014 reverse translation initiation factor IF-2 [EXP-IDA|W|Inferred from direct assay] 10748005,1100407,1106767,11120350,11497435,12718519,14698286,1702020,1720674,17913632,18318122,19366171,2125480,217406,21801766,2207173,22411911,23536416,2444251,2448483,24794712,25308340,2684975,2695390,28914580,30904393,320048,3533628,359327,393258,4197131,4314905,4562740,4569079,4872321,4876939,6096856,6214789,6306257,6340723,6349681,6799502,6989597,6990978,6997046,7538134,782882,805131,826536,8483930,8608135,8798391,8999877,9428651,9698545,9826553, Weak b3168 ECK120000498 infB b3168 3313342 3316014 reverse translation initiation factor IF-2β [EXP-IDA|W|Inferred from direct assay] 10748005,1100407,1106767,11120350,11497435,12718519,14698286,1702020,1720674,17913632,18318122,19366171,2125480,217406,21801766,2207173,22411911,23536416,2444251,2448483,24794712,25308340,2684975,2695390,28914580,30904393,320048,3533628,359327,393258,4197131,4314905,4562740,4569079,4872321,4876939,6096856,6214789,6306257,6340723,6349681,6799502,6989597,6990978,6997046,7538134,782882,805131,826536,8483930,8608135,8798391,8999877,9428651,9698545,9826553, b3168 ECK120000658 nusA b3169 3316039 3317526 reverse transcription termination/antitermination protein NusA [EXP-IMP|W|Inferred from mutant phenotype] 6265784,6265785, Weak b3169 ECK120001161 rimP b3170 3317554 3318006 reverse ribosome maturation factor RimP [EXP-IMP|W|Inferred from mutant phenotype] 19150615,30219894, Weak b3170 ECK120002503 metY b3171 3318213 3318289 reverse tRNA-initiator Met(CAU) [AS-TAS|W|Traceable author statement] 25246575,27698115,7033244, Weak b3171 ECK120000064 argG b3172 3318637 3319980 forward argininosuccinate synthetase b3172 ECK120004205 yhbX b3173 3319988 3321613 reverse putative hydrolase YhbX 16514146, b3173 ECK120002492 leuU b3174 3322072 3322158 reverse tRNA-Leu(GAG) [AS-TAS|W|Traceable author statement] 7033244, Weak b3174 ECK120002000 secG b3175 3322173 3322505 reverse Sec translocon subunit SecG 10521500,8641431,9644254,9829959, b3175 ECK120001506 glmM b3176 3322733 3324070 reverse phosphoglucosamine mutase b3176 ECK120002570 folP b3177 3324063 3324911 reverse dihydropteroate synthase 12618467,1522070,8244950, b3177 ECK120001462 ftsH b3178 3325001 3326935 reverse ATP-dependent zinc metalloprotease FtsH 10650212,1551860,9197418, b3178 ECK120001463 rlmE b3179 3327035 3327664 reverse 23S rRNA 2'--ribose U2552 methyltransferase 12527203,20719918,22411911,23015474,30799486, b3179 ECK120002385 yhbY b3180 3327790 3328083 forward ribosome assembly factor YhbY [COMP-HINF|W|Inferred by a human based on computational evidence],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 12429100,23228329,27732863,28334975, Weak b3180 ECK120000408 greA b3181 3328239 3328715 reverse transcription elongation factor GreA [EXP-IDA|W|Inferred from direct assay],[EXP|W|Inferred from experiment] 12486015,1384037,1885509,20008510,7513426,7538676,7932713, Weak b3181 ECK120000196 dacB b3182 3328963 3330396 forward peptidoglycan DD-endopeptidase DacB b3182 ECK120004206 obgE b3183 3330582 3331754 reverse GTPase ObgE [EXP-IDA|W|Inferred from direct assay] 15004283,22246579,23228329,24844575,34326822, Weak b3183 ECK120001455 yhbE b3184 3331770 3332735 reverse putative transporter YhbE 31438868, b3184 ECK120002561 rpmA b3185 3332862 3333119 reverse 50S ribosomal subunit protein L27 11412118,11673426,11904182,22634088,8722019,8722036, b3185 ECK120002560 rplU b3186 3333140 3333451 reverse 50S ribosomal subunit protein L21 b3186 ECK120000015 ispB b3187 3333710 3334681 forward -octaprenyl-diphosphate synthase b3187 ECK120000649 sfsB b3188 3334909 3335187 forward putative transcriptional regulator SfsB [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 2670911, Weak b3188 ECK120001327 murA b3189 3335235 3336494 reverse UDP--acetylglucosamine 1-carboxyvinyltransferase 22847918, b3189 ECK120004207 ibaG b3190 3336549 3336803 reverse acid stress protein IbaG [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15556475,22847918, Weak b3190 ECK120004208 mlaB b3191 3336963 3337256 reverse intermembrane phospholipid transport system protein MlaB 28388411,31235958,32602838,33236984, b3191 ECK120004209 mlaC b3192 3337256 3337891 reverse intermembrane phospholipid transport system - periplasmic binding protein [EXP-IMP|W|Inferred from mutant phenotype] 19383799,32955879, Weak b3192 ECK120002386 mlaD b3193 3337910 3338461 reverse intermembrane phospholipid transport system, substrate binding protein MlaD 31235958,32359438, b3193 ECK120002387 mlaE b3194 3338466 3339248 reverse intermembrane phospholipid transport system, integral membrane subunit MlaE 28388411,31235958, b3194 ECK120002388 mlaF b3195 3339256 3340065 reverse intermembrane phospholipid transport system, ATP binding subunit MlaF 28388411,31235958, b3195 ECK120002389 yrbG b3196 3340275 3341252 forward putative transport protein YrbG 20196076,31438868, b3196 ECK120004210 kdsD b3197 3341266 3342252 forward D-arabinose 5-phosphate isomerase KdsD b3197 ECK120004211 kdsC b3198 3342273 3342839 forward 3-deoxy-D--octulosonate 8-phosphate phosphatase KdsC 21669179,27173798, b3198 ECK120004212 lptC b3199 3342836 3343411 forward lipopolysaccharide transport system protein LptC 16820464,27246575,27529623,30723128, b3199 ECK120004213 lptA b3200 3343380 3343937 forward lipopolysaccharide transport system protein LptA 24123237,28419595,29109183,29332998,29672978,30443594,34070637, b3200 ECK120001623 lptB b3201 3343944 3344669 forward lipopolysaccharide transport system ATP binding protein LptB 27246575, b3201 ECK120000889 rpoN b3202 3344717 3346150 forward RNA polymerase sigma factor RpoN 26425847, b3202 ECK120001624 hpf b3203 3346173 3346460 forward ribosome hibernation-promoting factor [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 17277072,18174192,23228329,23663662,27939605,30661150,32649051,33693886,34486756, Weak b3203 ECK120001625 ptsN b3204 3346578 3347069 forward phosphotransferase system enzyme IIA(Ntr) [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 17289841,19400808,22812494,26159077, Weak b3204 ECK120002046 rapZ b3205 3347115 3347969 forward RNase adaptor protein RapZ b3205 ECK120002047 npr b3206 3347966 3348238 forward phosphorelay protein NPr [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10473571,16164569,21605551,7876255, Strong b3206 ECK120004214 yrbL b3207 3348452 3349084 forward protein kinase-like domain-containing protein YrbL 22442305,27252779, b3207 ECK120004215 mtgA b3208 3349081 3349809 reverse peptidoglycan glycosyltransferase MtgA 15375124,8830253, b3208 ECK120001350 elbB b3209 3349806 3350459 reverse low activity glyoxalase ElbB b3209 ECK120002583 arcZ b4450 3350577 3350697 forward small regulatory RNA ArcZ [EXP-IMP|W|Inferred from mutant phenotype] 20457943,23659637,26469694,28794186,30287822, Weak b4450 ECK120000058 arcB b3210 3350689 3353025 reverse sensor histidine kinase ArcB 10393292,10531481,10585483,10734219,10851007,10947842,11148031,12366850,15522865,15838055,1597416,20097862,20498088,20709841,20946850,26828204,28553265,28923010,29945971,30904393,7957084,8825099,9054511,9188789,9286997,9489669,9685739,9761838,9972245, b3210 ECK120004216 yhcC b3211 3353121 3354050 reverse radical SAM family oxidoreductase YhcC b3211 ECK125135303 Phantom Gene 3354064 3354169 forward ECK120000396 gltB b3212 3354725 3359185 forward glutamate synthase subunit GltB b3212 ECK120000397 gltD b3213 3359198 3360616 forward glutamate synthase subunit GltD b3213 ECK120001469 gltF b3214 3361176 3361940 forward periplasmic protein GltF b3214 ECK120001470 yhcA b3215 3362112 3362786 forward putative fimbrial chaperone YhcA 20345943,21344461,23382825, b3215 ECK120004217 yhcD b3216 3362807 3365188 forward putative fimbrial usher protein YhcD 20345943,21344461,23382825, b3216 ECK120004219 insH10 b3218 3365702 3366682 reverse IS transposase and trans-activator b3218 ECK120004220 yhcF b3219 3366926 3367642 forward DUF1120 domain-containing protein YhcF b3219 ECK125135305 Phantom Gene 3367613 3367770 reverse ECK120004221 yhcG b3220 3367827 3368954 forward DUF1016 domain-containing protein YhcG [COMP|W|Inferred by computational analysis] 16011798, Weak b3220 ECK120004222 nanQ b3221 3369014 3369478 reverse -acetylneuraminate anomerase b3221 ECK120004223 nanK b3222 3369475 3370350 reverse -acetylmannosamine kinase b3222 ECK120004224 nanE b3223 3370347 3371036 reverse probable -acetylmannosamine-6-phosphate 2-epimerase 11447132,31557000,32572810, b3223 ECK120002695 nanT b3224 3371084 3372574 reverse symporter 20100283,2825630,31438868,7592358, b3224 ECK120000630 nanA b3225 3372683 3373576 reverse -acetylneuraminate lyase 19586552,22525748,24610847,29704158, b3225 ECK120004225 nanR b3226 3373698 3374489 reverse NanR b3226 ECK120004226 dcuD b3227 3374869 3376236 forward putative transporter DcuD 32700240, b3227 ECK120000967 sspB b3228 3376279 3376776 reverse ClpXP protease specificity-enhancing factor b3228 ECK120000966 sspA b3229 3376782 3377420 reverse stringent starvation protein A [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 12791143,2835636,3003520,3029697, Strong b3229 ECK120000899 rpsI b3230 3377815 3378207 reverse 30S ribosomal subunit protein S9 b3230 ECK120000865 rplM b3231 3378223 3378651 reverse 50S ribosomal subunit protein L13 11474114,11931584,15126466,2419169,24494973,27381917,3541786,365580,3884974,4598298,6341055,6365649,7035437, b3231 ECK120004227 zapE b3232 3378870 3379997 reverse cell division protein ZapE [EXP-IMP|W|Inferred from mutant phenotype] 24595368, Weak b3232 ECK120004228 zapG b3233 3380191 3380589 forward Z-ring associated protein G [EXP-IPI|W|Inferred from physical interaction],[EXP-IGI|W|Inferred from genetic interaction] 18180259,21695201,24391520,27335665, Weak b3233 ECK120004229 degQ b3234 3380743 3382110 forward periplasmic serine endoprotease b3234 ECK120001596 degS b3235 3382200 3383267 forward serine endoprotease b3235 ECK120000569 mdh b3236 3383330 3384268 reverse malate dehydrogenase b3236 ECK120000066 argR b3237 3384703 3385173 forward DNA-binding transcriptional dual regulator ArgR 3116542,3149585,4555419,7997172, b3237 ECK120004230 yhcN b3238 3385538 3385801 forward DUF1471 domain-containing stress-induced protein YhcN [EXP-IMP|W|Inferred from mutant phenotype] 19919618,27252779, Weak b3238 ECK120004231 yhcO b3239 3385857 3386129 reverse putative barnase inhibitor b3239 ECK120004232 aaeB b3240 3386221 3388188 reverse aromatic carboxylic acid efflux pump subunit AaeB b3240 ECK120004233 aaeA b3241 3388194 3389126 reverse aromatic carboxylic acid efflux pump membrane fusion protein 17664315, b3241 ECK120004234 aaeX b3242 3389134 3389337 reverse DUF1656 domain-containing protein AaeX 17145952, b3242 ECK120004235 aaeR b3243 3389520 3390449 forward DNA-binding transcriptional activator AaeR [COMP-HINF|W|Inferred by a human based on computational evidence],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 10734204,12011002,15489430,15556475, Weak b3243 ECK120004236 tldD b3244 3390583 3392028 reverse metalloprotease subunit TldD b3244 ECK120004237 yhdP b4472 3392458 3396258 reverse phospholipid transport factor YhdP [EXP-IGI|W|Inferred from genetic interaction] 12234664,32323199,33046656, Weak b3245,b3246,b4472 ECK120001272 rng b3247 3396326 3397795 reverse RNase G b3247 ECK120001271 yhdE b3248 3397785 3398378 reverse nucleoside triphosphate pyrophosphatase YhdE b3248 ECK120000603 mreD b3249 3398387 3398875 reverse cell shape determining protein MreD [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 15612918,17993535,2687239,33370261,33558391,34070637, Weak b3249 ECK120000602 mreC b3250 3398875 3399978 reverse cell shape determining protein MreC b3250 ECK120000601 mreB b3251 3400044 3401087 reverse dynamic cytoskeletal protein MreB [COMP-HINF|W|Inferred by a human based on computational evidence],[EXP-IDA-UNPURIFIED-PROTEIN-NH|W|Assay of unpurified protein expressed in its native host],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ] 12596863,1323828,14517265,15612918,16109960,16262780,17993535,19111750,19164570,19220747,19346310,20168300,20439764,21419100,23301723,23756461,24550500,25456141,26396257,2687239,27602731,28164388,2822655,28230084,29103935,30335755,30951524,31993609,33330621,4892376, Weak b3251 ECK120000016 csrD b3252 3401392 3403332 reverse regulator of CsrB and CsrC decay b3252 ECK120001286 yhdH b3253 3403484 3404458 forward acrylyl-CoA reductase b3253 ECK125240989 yrdF b4697 3404495 3404637 forward b4697 ECK120004238 b3254 b3254 3404516 3404617 reverse ECK125240974 yrdE b4646 3404638 3405031 forward b4646 ECK120000269 accB b3255 3405436 3405906 forward biotin carboxyl carrier protein [EXP|W|Inferred from experiment] 2575489,2660106,2822655,7945216, Weak b3255 ECK120000270 accC b3256 3405917 3407266 forward biotin carboxylase b3256 ECK120004239 yhdT b3257 3407375 3407617 forward DUF997 domain-containing protein YhdT b3257 ECK120000678 panF b3258 3407607 3409058 forward pantothenate:Na symporter b3258 ECK120001453 prmA b3259 3409070 3409951 forward ribosomal protein L11 methyltransferase 10997488, b3259 ECK120001282 dusB b3260 3410280 3411245 forward tRNA-dihydrouridine synthase B 27718375, b3260 ECK120000311 fis b3261 3411271 3411567 forward DNA-binding transcriptional dual regulator Fis 1547773,27718375,7545153, b3261 ECK120001454 yhdJ b3262 3411653 3412537 forward DNA adenine methyltransferase b3262 ECK120004240 yhdU b3263 3412621 3412800 forward DUF2556 domain-containing protein YhdU b3263 ECK120001680 envR b3264 3412803 3413465 reverse DNA-binding transcriptional repressor EnvR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 18567659,7592375,8196548, Weak b3264 ECK120000260 acrE b3265 3413864 3415021 forward multidrug efflux pump membrane fusion lipoprotein AcrE 15174130,1720861,31438868,32053772, b3265 ECK120000261 acrF b3266 3415033 3418137 forward multidrug efflux pump RND permease AcrF 27105118,31251753, b3266 ECK120004241 yhdV b3267 3418390 3418611 forward lipoprotein YhdV 32053772, b3267 ECK120002391 yhdW b3268 3419042 3420066 forward putative ABC transporter periplasmic binding protein YhdW 31438868, b3268 ECK120002392 yhdX b3269 3420134 3421315 forward putative ABC transporter membrane subunit YhdX 31438868, b3269 ECK120002393 yhdY b3270 3421325 3422428 forward putative ABC transporter membrane subunit YhdY 31438868, b3270 ECK120002394 yhdZ b3271 3422436 3423194 forward putative ABC transporter ATP-binding subunit YhdZ 31438868, b3271 ECK120002533 rrfF b3272 3423423 3423542 reverse 5S ribosomal RNA [EXP-TAS|W|Traceable author statement to experimental support] 11401702,11488615,164889,1709493,1709723,1718749,1764510,2190187,2412207,2493632,3013618,3089782,324975,327272,331075,3315008,342117,359042,4198187,4216514,4550693,4571522,4591367,4609878,4621557,4881049,4881332,4906324,4906608,4918254,4920877,4924729,4931952,4944480,4993318,6178431,6188537,6255417,6390428,6765232,7024913,782717,805122,810137,95791,9862991,9878392, Weak b3272 ECK120002545 thrV b3273 3423580 3423655 reverse tRNA-Thr(GGU) [AS-TAS|W|Traceable author statement] 23295341,6761541,7033244, Weak b3273 ECK120002515 rrfD b3274 3423668 3423787 reverse 5S ribosomal RNA [EXP-TAS|W|Traceable author statement to experimental support] 11401702,11488615,164889,1709493,1709723,1718749,1764510,2190187,2412207,2493632,3013618,3089782,324975,327272,331075,3315008,342117,359042,4198187,4216514,4550693,4571522,4591367,4609878,4621557,4881049,4881332,4906324,4906608,4918254,4920877,4924729,4931952,4944480,4993318,6178431,6188537,6255417,6390428,6765232,7024913,782717,805122,810137,95791,9862991,9878392, Weak b3274 ECK120002522 rrlD b3275 3423880 3426783 reverse 23S ribosomal RNA [EXP-TAS|W|Traceable author statement to experimental support] 10051579,10464195,10525403,10793686,10844684,1094419,10964562,10986461,1098691,1101264,1102922,1103090,1103124,11157269,11350034,11517305,11574482,11675490,11680845,11741781,11751827,11888286,11955006,11991636,12022228,12034826,12467398,12498,12533472,12888505,1719209,1918155,1981803,2197598,2407189,2473375,3013618,3048270,3053641,3060850,3089782,319193,319197,3226909,325525,327272,327273,3277949,329865,331075,331313,3313279,3329282,342117,355851,359042,388189,3894326,390405,407931,4563865,4584388,4918356,4931952,4942898,4943519,6158039,6162473,6170632,6173374,6193815,6255418,6349628,6361011,6750359,6996708,7016337,7041903,7514294,7529560,7567991,7601845,7682175,775291,782716,782717,785385,789334,791272,8031879,805122,8253085,8515441,8524828,8643399,8643630,8654409,8710862,8834779,8918803,9016593,9034358,9135982,9367788,9396814,9501232,9573162,9586034,9620960,9769102,9836593,9989214, Weak b3275 ECK120002452 alaU b3276 3426958 3427033 reverse tRNA-Ala(UGC) [AS-TAS|W|Traceable author statement] 7033244, Weak b3276 ECK120002486 ileU b3277 3427076 3427152 reverse tRNA-Ile(GAU) [AS-TAS|W|Traceable author statement] 7033244, Weak b3277 ECK120002529 rrsD b3278 3427221 3428762 reverse 16S ribosomal RNA 10753935,10844684,10919826,1094419,1101264,1102922,1103124,110460,11751827,12087167,12498,12902289,12903214,14510386,1646122,1716101,1718749,1764510,1764516,2145040,2168847,2222527,2387410,2435709,2443830,2448485,2473375,2685545,2689447,2833391,3013618,3071662,3071664,319193,320561,326259,327272,327273,3277949,331075,331313,3313279,3329282,342117,344139,348233,365689,378405,383432,384145,3894326,390405,392468,407931,4560773,4564202,4918356,4942898,4943519,6285294,6330033,6361011,6752954,6995826,7516168,7601845,769922,7718670,782716,782717,789334,793615,8041615,8312257,8377198,8419334,8515441,9034358,9226253,9501232,9769102, b3278 ECK120004242 yrdA b3279 3429236 3429790 forward hexapeptide repeats-containing protein YrdA b3279 ECK120004243 yrdB b3280 3429766 3430023 reverse DUF1488 domain-containing protein YrdB b3280 ECK120000073 aroE b3281 3430020 3430838 reverse shikimate dehydrogenase 10739937,11603966,12363343,14367339,14642355,16240440,16828913,20385022,22020510,22728194,23631118,24512078,24894540,26362984,26672454,27114316,28511681,29363372,30096230,3277621,3298978,33221881,9531423, b3281 ECK120004244 tsaC b3282 3430843 3431415 reverse L-threonylcarbamoyladenylate synthase 21810204,23258706, b3282 ECK120004245 yrdD b3283 3431420 3431962 reverse putative DNA topoisomerase 26774489, b3283 ECK120001553 smg b3284 3431991 3432464 reverse DUF494 domain-containing protein Smg b3284 ECK120001552 smf b4473 3432436 3433560 reverse protein Smf 31608580, b3285,b3286,b4473 ECK120001404 def b3287 3433690 3434199 forward peptide deformylase 19191548,19922819,21603885,24939037, b3287 ECK120001242 fmt b3288 3434214 3435161 forward 10-formyltetrahydrofolate:L-methionyl-tRNA-formyltransferase 4920879, b3288 ECK120002059 rsmB b3289 3435207 3436496 forward 16S rRNA mC967 methyltransferase 23530111, b3289 ECK120001008 trkA b3290 3436518 3437894 forward NAD-binding component of Trk potassium transporters [EXP-IPI|W|Inferred from physical interaction],[EXP-IGI|W|Inferred from genetic interaction] 1987159,2674131,3298214,4942756,7042336,8412700, Weak b3290 ECK120001162 mscL b3291 3438024 3438434 forward large conductance mechanosensitive channel 10050752,10625640,10637638,10801868,11224560,11479346,11557017,12015316,12046893,12198480,12446894,14640699,15041653,15041744,15205426,15228529,15301476,15542561,15812636,15812637,15959773,16288836,16751236,17307828,17480116,18341289,18950196,19261722,20876362,22206349,22874845,24038743,24550255,24958207,25223610,25404294,25697390,26143502,26348441,26368283,27708587,28166450,28345591,28859093,30201782,30206263,31765130,31783284,7543101,8890153,9126353,9336188,9405414,9528681,9614061,9632260, b3291 ECK120016317 arfA b4550 3438431 3438649 reverse alternative ribosome-rescue factor A [EXP-IDA|W|Inferred from direct assay] 21062370,26863752,28702280,29382730,30375330,32727848, Weak b4550 ECK120001894 zntR b3292 3438705 3439130 reverse DNA-binding transcriptional activator ZntR [EXP-IDA-BINDING-OF-PURIFIED-PROTEINS|S|Binding of purified proteins],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 10048032,10608803,10802061,12445820, Strong b3292 ECK120001895 yhdN b3293 3439141 3439509 reverse DUF1992 domain-containing protein YhdN b3293 ECK120000869 rplQ b3294 3439616 3439999 reverse 50S ribosomal subunit protein L17 b3294 ECK120000884 rpoA b3295 3440040 3441029 reverse RNA polymerase subunit α b3295 ECK120000894 rpsD b3296 3441055 3441675 reverse 30S ribosomal subunit protein S4 1091486,19386726,23431409,24494973,2989779,4591618,4606155,8371264, b3296 ECK120000901 rpsK b3297 3441709 3442098 reverse 30S ribosomal subunit protein S11 10376881,1100375,1108010,11243814,21030658,2427338,2455862,25421,2578985,2582234,2989779,3054504,3126824,332690,338911,349353,3512304,3542056,3889589,3897787,3908910,395318,4579428,4592687,4595567,4897206,6085011,6154696,6202554,6209544,6211432,6251471,6341200,6354253,6371250,6390176,6445562,6750359,7024784,7024914,7040690,7516877,7585249,765480,772215,782519,787927,791359,804486,9004854,9281425, b3297 ECK120000903 rpsM b3298 3442115 3442471 reverse 30S ribosomal subunit protein S13 1107023,11341947,1382439,1397315,20188109,2207167,22268863,2413345,2413346,2451022,2461734,2466901,2483051,2582234,2660905,27145979,3087780,3126824,3288761,3311162,332690,336508,349353,3512304,3542056,363701,372749,380646,3889589,3897787,3897833,4205593,4556459,4592687,4610565,4614073,4618476,6085011,6163479,6202554,6351913,6354253,6369248,6390176,6750359,6995826,7002551,7024784,7024914,7031657,7043397,7047161,765480,7689558,776616,782519,791359,794830,805140,8058729,8360163,9004854,9281425, b3298 ECK120001210 rpmJ b3299 3442618 3442734 reverse 50S ribosomal subunit protein L36 2671645,33639093,8722036, b3299 ECK120000757 secY b3300 3442766 3444097 reverse Sec translocon subunit SecY 11445571,12220653,12756530,12809500,1588819,2535843,2538820,26459600,2848248,8083155,8183945,8190079,9451453, b3300 ECK120000867 rplO b3301 3444105 3444539 reverse 50S ribosomal subunit protein L15 b3301 ECK120000879 rpmD b3302 3444543 3444722 reverse 50S ribosomal subunit protein L30 b3302 ECK120000895 rpsE b3303 3444726 3445229 reverse 30S ribosomal subunit protein S5 19969550,24671761,24966114, b3303 ECK120000870 rplR b3304 3445244 3445597 reverse 50S ribosomal subunit protein L18 16930151,22821559, b3304 ECK120000860 rplF b3305 3445607 3446140 reverse 50S ribosomal subunit protein L6 11931584,27003253,324885,6354754,6360687,6756916,799248, b3305 ECK120000898 rpsH b3306 3446153 3446545 reverse 30S ribosomal subunit protein S8 108264,330244,359353, b3306 ECK120000904 rpsN b3307 3446579 3446884 reverse 30S ribosomal subunit protein S14 1100389,2200507,2413345,2413346,2437442,2582234,28096346,3054504,3087780,3126824,3279390,3280567,3311162,332690,332691,33649148,3541786,3542056,380646,3889589,3897833,3908910,407081,4140507,4205593,4592687,4612245,4614073,4618476,4998702,6153807,6182899,6202554,6209544,6350302,6354253,6371250,6397477,6750359,776616,782519,794830,805140,8058729,8722010,8722036,9004854, b3307 ECK120000859 rplE b3308 3446899 3447438 reverse 50S ribosomal subunit protein L5 1089427,1092342,109811,1104622,12809609,141001,15178758,1693861,1702198,1709494,19469554,22268863,2429677,2504932,2653827,2664451,327280,3298242,3298260,332690,332691,338605,3512304,3541786,3542048,388442,3905404,393829,414209,4616944,6159586,6160475,6174328,6222285,6349628,6349680,6358224,6365649,6385986,6437621,68433,7019670,7794529,791646,791672,8722010,8925931,9430711, b3308 ECK120000875 rplX b3309 3447453 3447767 reverse 50S ribosomal subunit protein L24 10329160,11470155,18158904,2465415,2578985,2660905,30475203,3298242,332690,334534,338919,3512304,3541786,3542056,364413,374386,378134,3889589,3896776,391595,6222285,6345195,6361486,6381990,6445562,6998892,71068,786630,787753,799248,876027,9371771,9813114, b3309 ECK120000866 rplN b3310 3447778 3448149 reverse 50S ribosomal subunit protein L14 10329160, b3310 ECK120000907 rpsQ b3311 3448314 3448568 reverse 30S ribosomal subunit protein S17 10376881,1646122,20600110,22178475,22654657,231998,2582234,2660905,2689654,28483689,321934,3280567,3288761,3297162,332690,351619,385060,3908910,3926498,407946,6200766,6209544,6209548,6266618,6354754,6361486,6751823,775293,791359,794830,8722036,9004854,9281425,9371771, b3311 ECK120000878 rpmC b3312 3448568 3448759 reverse 50S ribosomal subunit protein L29 b3312 ECK120000868 rplP b3313 3448759 3449169 reverse 50S ribosomal subunit protein L16 10625493,109811,1102306,1706660,18755834,2040621,2182126,2495985,2504932,2645289,2653827,2664777,2665813,321934,332690,334534,336360,33639093,340794,348495,350280,3512304,3541786,363428,386275,387084,3881259,4589893,4598298,6084168,6163479,6402016,6765232,68433,7030408,786630,786730,9371771, b3313 ECK120000893 rpsC b3314 3449182 3449883 reverse 30S ribosomal subunit protein S3 b3314 ECK120000873 rplV b3315 3449901 3450233 reverse 50S ribosomal subunit protein L22 11412118,160567,16061180,17293420,19015512,19150357,19197244,19469554,19933110,20481440,20804452,2185470,22362747,23625843,23871456,2419169,2463164,27257065,30753870,30988366,31594941,332690,340907,350280,354931,384161,387084,3892488,4280012,4614072,6159923,6174328,68433,7007072,7047160,799248, b3315 ECK120000909 rpsS b3316 3450248 3450526 reverse 30S ribosomal subunit protein S19 b3316 ECK120000856 rplB b3317 3450543 3451364 reverse 50S ribosomal subunit protein L2 b3317 ECK120000874 rplW b3318 3451382 3451684 reverse 50S ribosomal subunit protein L23 b3318 ECK120000858 rplD b3319 3451681 3452286 reverse 50S ribosomal subunit protein L4 20139416,20876128,22362747,23396277,30988366,32123036,32144191, b3319 ECK120000857 rplC b3320 3452297 3452926 reverse 50S ribosomal subunit protein L3 b3320 ECK120000900 rpsJ b3321 3452959 3453270 reverse 30S ribosomal subunit protein S10 1531224,18177898,1831176,19111659, b3321 ECK120001238 gspB b3322 3453508 3453927 reverse putative general secretion pathway protein B 1938934, b3322 ECK120004246 gspA b3323 3453929 3455398 reverse Type II secretion system protein GspA b3323 ECK120004247 gspC b3324 3455578 3456393 forward Type II secretion system protein GspC b3324 ECK120004248 gspD b3325 3456377 3458329 forward Type II secretion system protein GspD b3325 ECK120004249 gspE b3326 3458339 3459820 forward Type II secretion system protein GspE b3326 ECK120004250 gspF b3327 3459817 3461013 forward Type II secretion system protein GspF b3327 ECK120004251 gspG b3328 3461023 3461460 forward Type II secretion system protein GspG b3328 ECK120004252 gspH b3329 3461468 3461977 forward Type II secretion system protein GspH b3329 ECK120004253 gspI b3330 3461974 3462351 forward Type II secretion system protein GspI b3330 ECK120004254 gspJ b3331 3462344 3462931 forward Type II secretion system protein GspJ b3331 ECK120004255 gspK b3332 3462924 3463907 forward Type II secretion system protein GspK b3332 ECK120004256 gspL b3333 3463922 3465085 forward Type II secretion system protein GspL b3333 ECK120002068 gspM b3334 3465082 3465543 forward Type II secretion system protein GspM b3334 ECK120001328 gspO b3335 3465543 3466220 forward Type II secretion system prepilin peptidase b3335 ECK120000109 bfr b3336 3466249 3466725 reverse bacterioferritin 10506413,11330712,11878806,1549605,17400245,19705876,2083739,21215826,25107631,3060115,3904732,6994819,8944892,8955338, b3336 ECK120001163 bfd b3337 3466797 3466991 reverse bacterioferritin-associated ferredoxin 2661540, b3337 ECK120001215 chiA b3338 3467160 3469853 reverse endochitinase 10760150,23684751,30846972, b3338 ECK120001025 tufA b3339 3470145 3471329 reverse translation elongation factor Tu 1 1573997,9868784, b3339 ECK120000353 fusA b3340 3471400 3473514 reverse elongation factor G 31911945,4551984,4881331,5542892, b3340 ECK120000897 rpsG b3341 3473542 3474081 reverse 30S ribosomal subunit protein S7 b3341 ECK120000902 rpsL b3342 3474178 3474552 reverse 30S ribosomal subunit protein S12 18234219,18355719,19187763,19469554,19553343,20043920,21138965,21378755,22268863,22388519,23972615,24133211,24412368,24966114,24968035,25594181, b3342 ECK120004257 tusB b3343 3474678 3474965 reverse sulfurtransferase complex subunit TusB b3343 ECK120004258 tusC b3344 3474973 3475332 reverse sulfurtransferase complex subunit TusC b3344 ECK120004259 tusD b3345 3475332 3475718 reverse sulfurtransferase complex subunit TusD b3345 ECK120004260 yheO b3346 3475718 3476440 reverse DNA-binding transcriptional regulator YheO [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IPI|W|Inferred from physical interaction] 15556475,30137486, Weak b3346 ECK120004261 fkpA b3347 3476607 3477419 reverse peptidyl-prolyl isomerase FkpA [EXP|W|Inferred from experiment] Weak b3347 ECK120001607 slyX b3348 3477640 3477858 forward protein SlyX b3348 ECK120001606 slyD b3349 3477907 3478497 reverse FKBP-type peptidyl-prolyl isomerase SlyD 12630907,16814929,21466862,21661729,23268194,23445547,23871892,25824521,28176839,28315745,28668496,29626483,32813023, b3349 ECK120016318 yheV b4551 3478592 3478792 reverse DUF2387 domain-containing protein YheV b4551 ECK120002444 kefB b3350 3478802 3480607 reverse K antiporter KefB b3350 ECK120004262 kefG b3351 3480607 3481161 reverse glutathione-regulated potassium-efflux system ancillary protein KefG [EXP-IMP|W|Inferred from mutant phenotype] 11053405, Weak b3351 ECK120002423 yheS b3352 3481289 3483202 forward putative ATP-binding protein YheS [COMP-HINF|W|Inferred by a human based on computational evidence],[EXP-IGI|W|Inferred from genetic interaction] 28911185,31438868,9593292, Weak b3352 ECK120004263 yheT b3353 3483202 3484224 forward putative hydrolase YheT [COMP-HINF|W|Inferred by a human based on computational evidence] 9889164, Weak b3353 ECK120004264 yheU b3354 3484218 3484436 forward PF06794 family protein YheU b3354 ECK120002233 prkB b3355 3484490 3485359 forward putative phosphoribulokinase b3355 ECK120001164 yhfA b3356 3485414 3485818 reverse OsmC family protein YhfA b3356 ECK120000160 crp b3357 3486120 3486752 forward DNA-binding transcriptional dual regulator CRP [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 10760178,11742992,12923087,1328816,14638413,15520470,16166533,7551052,8604346, Weak b3357 ECK120004265 yhfK b3358 3486791 3488893 forward putative transporter YhfK 24391520,31438868, b3358 ECK120000062 argD b3359 3488960 3490180 reverse -succinyldiaminopimelate aminotransferase 10074354,2199330, b3359 ECK125303720 yrfJ b4820 3490132 3490185 reverse protein YrfJ b4820 ECK120000675 pabA b3360 3490266 3490829 reverse aminodeoxychorismate synthase subunit 2 3291877,6350604, b3360 ECK120000301 fic b3361 3490861 3491463 reverse putative adenosine monophosphate—protein transferase Fic [EXP-IMP|W|Inferred from mutant phenotype] 14704342,1656497,2050628,2403545, Weak b3361 ECK120002242 yhfG b3362 3491453 3491620 reverse DUF2559 domain-containing protein YhfG b3362 ECK120000748 ppiA b3363 3491725 3492297 reverse peptidyl-prolyl isomerase A b3363 ECK120001237 tsgA b3364 3492568 3493749 forward putative transporter TsgA b3364 ECK120000646 nirB b3365 3494011 3496554 forward nitrite reductase (NADH) large subunit 2173895,2200672,24203355,6262434, b3365 ECK120000648 nirD b3366 3496551 3496877 forward nitrite reductase (NADH) small subunit [EXP-IDA|W|Inferred from direct assay] 2200672,34323689,368584,3906030, Weak b3366 ECK120000647 nirC b3367 3497003 3497809 forward nitrite transporter NirC 16804183,31438868, b3367 ECK120000183 cysG b3368 3497828 3499201 forward siroheme synthase 2158792,2200672, b3368 ECK120004266 yhfL b3369 3499448 3499615 forward DUF4223 domain-containing lipoprotein YhfL 15174130, b3369 ECK120002424 frlA b3370 3499910 3501247 forward fructoselysine/psicoselysine transporter b3370 ECK120004267 frlB b3371 3501268 3502290 forward fructoselysine 6-phosphate deglycase b3371 ECK120004268 frlC b4474 3502340 3503170 forward fructoselysine 3-epimerase b3372,b3373,b4474 ECK120004269 frlD b3374 3503167 3503952 forward fructoselysine 6-kinase b3374 ECK120004270 frlR b3375 3504052 3504783 forward DNA-binding transcriptional regulator FrlR [COMP-HINF-ORTHOLOGY-EXP|W|Human inference of function based on ortholog with experimental function in closely related strain or species.] 32979851, Weak b3375 ECK120004271 yhfS b3376 3504935 3506020 reverse putative aminotransferase YhfS b3376 ECK120004272 yhfT b3377 3506032 3507336 reverse uncharacterized protein YhfT b3377 ECK120004273 yhfU b3378 3507348 3507701 reverse DUF2620 domain-containing protein YhfU b3378 ECK120004274 php b3379 3507712 3508590 reverse putative hydrolase b3379 ECK120004275 yhfW b3380 3508587 3509813 reverse putative mutase YhfW b3380 ECK120004276 yhfX b3381 3509813 3510976 reverse putative PLP-binding protein YhfX b3381 ECK120004277 yhfY b3382 3511060 3511422 reverse PRD domain-containing protein YhfY b3382 ECK120004278 yhfZ b3383 3511439 3512344 reverse putative DNA-binding transcriptional regulator YhfZ b3383 ECK120001019 trpS b3384 3512634 3513638 reverse tryptophan—tRNA ligase 1508173,18713004,3078873,3078874,334569,353515,379831,3886424,4555910,4582891,4895848,4914847,6337120,6389500,7042706,776964,781267, b3384 ECK120001802 gph b3385 3513631 3514389 reverse phosphoglycolate phosphatase 12469338,16760308, b3385 ECK120004466 rpe b3386 3514382 3515059 reverse ribulose-phosphate 3-epimerase b3386 ECK120000198 dam b3387 3515077 3515913 reverse DNA adenine methyltransferase 11004192,11072067,11111047,11371527,11439190,12067334,12897023,12944412,1420312,14643657,15009887,15225322,15387814,15489426,1551854,15534208,1581360,15925551,159363,1630320,16352851,16556234,16644499,16677308,167279,16787973,17114935,17727900,17827074,18282299,1870978,18824089,19079575,19236706,2013413,2155405,2190555,2204708,22373925,2257623,2546039,25475788,2549371,25785689,2642600,2659431,2661181,2671654,2693949,27718375,2828936,2829967,2972909,2976881,3054812,3074005,3074007,3074008,3074010,3301526,330882,3313278,3314290,350859,3512517,3512529,3531809,3536887,3549359,355857,361700,364302,370402,375073,378259,384219,3880739,3932821,3937030,4956424,6094478,6218410,6229339,6233141,6254852,6287993,6296768,6300769,6316110,6336742,6353164,6368265,6376282,6377015,6395666,6443311,6444406,6750321,6752951,6987663,6993844,7028433,7038402,7603433,7607492,7748925,7891562,7928948,7934887,799245,8011018,8168484,8195106,8320213,8589248,8647421,8692955,8813050,8824767,8845361,8918477,8981994,9426127,9580708,9624689,9811649, b3387 ECK120001165 damX b3388 3516020 3517306 reverse cell division protein DamX [EXP-IGI|W|Inferred from genetic interaction] 19684127, Weak b3388 ECK120000070 aroB b3389 3517398 3518486 reverse 3-dehydroquinate synthase 3009224, b3389 ECK120000077 aroK b3390 3518543 3519064 reverse shikimate kinase 1 11953442,1630320,16828913,23383718,23631118,24079972,24894540,27406890,28044275,7612934,9379896, b3390 ECK120002017 hofQ b3391 3519465 3520703 reverse DNA utilization protein HofQ [EXP-IMP|W|Inferred from mutant phenotype] 11591672,16707682, Weak b3391 ECK120004279 hofP b3392 3520615 3521019 reverse DNA utilization protein HofP [EXP-IMP|W|Inferred from mutant phenotype] 16707682, Weak b3392 ECK120004280 hofO b3393 3521009 3521449 reverse DNA utilization protein HofO [EXP-IMP|W|Inferred from mutant phenotype] 16707682, Weak b3393 ECK120004281 hofN b3394 3521433 3521972 reverse DNA utilization protein HofN [EXP-IMP|W|Inferred from mutant phenotype] 16707682, Weak b3394 ECK120004282 hofM b3395 3521972 3522751 reverse DNA utilization protein HofM [EXP-IMP|W|Inferred from mutant phenotype] 16707682, Weak b3395 ECK120000739 mrcA b3396 3522871 3525423 forward peptidoglycan glycosyltransferase / peptidoglycan DD-transpeptidase MrcA 1103132,17938168,2061284,2066344,22606933,24341982,2666392,31904338,378927,3898066,6751815,7001458,7592397,9244263,9324260, b3396 ECK120004283 nudE b3397 3525589 3526149 reverse ADP-sugar diphosphatase NudE 29529101, b3397 ECK120004284 igaA b3398 3526469 3528604 forward inner membrane protein IgaA [EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ] 25525882,28691662,29257832,29852010, Weak b3398 ECK120004285 yrfG b3399 3528669 3529337 forward purine nucleotidase b3399 ECK120004286 hslR b3400 3529348 3529749 forward heat shock protein Hsp15 [EXP-IDA|W|Inferred from direct assay],[EXP-IPI|W|Inferred from physical interaction] 10675343,19013177,30904393, Weak b3400 ECK120004287 hslO b3401 3529774 3530652 forward molecular chaperone Hsp33 [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 10025400,11323724,14685279,18287020,22385960,23148222, Weak b3401 ECK120004288 yhgE b3402 3530715 3532439 reverse putative transport protein YhgE b3402 ECK120000681 pck b3403 3532818 3534440 forward phosphopyruvate carboxykinase (ATP) 12383254,1701430,7028726,7548162,7875332,7883719,8141999,8895092,9048893,9406547,9716386,9951527, b3403 ECK120000263 envZ b3404 3534516 3535868 reverse sensor histidine kinase EnvZ 10426948,11158569,115844,11799122,12139613,12754242,1311295,1700256,1718943,17609131,17609132,17628148,17635923,1901856,20380141,2277042,2407554,25445668,2557454,25937465,26427760,2668953,26799494,27155567,2826400,28423182,2851704,3056929,3294816,32979869,334723,3536870,7997160,8106326,8458837,8576133,8899716,9409762, b3404 ECK120000665 ompR b3405 3535865 3536584 reverse DNA-binding transcriptional dual regulator OmpR b3405 ECK120001530 greB b3406 3536812 3537288 forward transcription elongation factor GreB [EXP|W|Inferred from experiment] 12486015,7513426,7538676,8902815,9038220,9334329,9512710,9733798, Weak b3406 ECK120004289 yhgF b3407 3537385 3539706 forward putative RNA-binding protein YhgF b3407 ECK120002006 feoA b3408 3540163 3540390 forward ferrous iron transport protein A [EXP-IMP|W|Inferred from mutant phenotype] 8407793, Weak b3408 ECK120002007 feoB b3409 3540407 3542728 forward Fe transporter FeoB 26067172,27332122, b3409 ECK120002425 feoC b3410 3542728 3542964 forward ferrous iron transport protein FeoC b3410 ECK120001688 rpnA b3411 3543167 3544045 forward recombination-promoting nuclease RpnA b3411 ECK120000118 bioH b3412 3544074 3544844 reverse pimeloyl-acyl carrier protein methyl ester esterase b3412 ECK120004290 yhgH b3413 3544882 3545565 forward DNA utilization protein YhgH [EXP-IMP|W|Inferred from mutant phenotype] 16707682, Weak b3413 ECK120004291 nfuA b3414 3545624 3546199 forward iron-sulfur cluster carrier protein NfuA 22210207, b3414 ECK120002247 gntT b3415 3546559 3547875 forward high-affinity gluconate transporter b3415 ECK120000554 malQ b3416 3547986 3550070 reverse 4-α-glucanotransferase 10198028,13125000,16321937,16980562,23950181,2423504,2845225,2946664,2986727,3038842,3156124,348525,4358043,4862709,4865925,4902812,4927807,4934064,5320292,6249703,6255466,6259122,7021525,791642,8366051, b3416 ECK120000553 malP b3417 3550080 3552473 reverse maltodextrin phosphorylase b3417 ECK120000555 malT b3418 3553085 3555790 forward DNA-binding transcriptional activator MalT 2524384,3015733, b3418 ECK120004292 rtcA b4475 3555833 3556849 reverse RNA 3'-terminal phosphate cyclase b3419,b3420,b4475 ECK120004293 rtcB b3421 3556853 3558079 reverse RNA-splicing ligase 26001965, b3421 ECK120002224 rtcR b3422 3558268 3559866 forward DNA-binding transcriptional activator RtcR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 9738023, Weak b3422 ECK120000393 glpR b3423 3559848 3560605 reverse DNA-binding transcriptional repressor GlpR [EXP|W|Inferred from experiment] 1556120,3316209,8955387, Weak b3423 ECK120000390 glpG b3424 3560622 3561452 reverse rhomboid protease GlpG 12620104,16621838,17493126,17714936,17938163,21175222,21256137,22035660,22688815,22705210,22770371,22921757,23150798,23353827,25009246,25162988,25307614,26032951,26056273,26166068,26218717,26479439,26605622,26716760,26858402,26999782,28069810,28373355,32795403,32848056,33554862, b3424 ECK120000388 glpE b3425 3561497 3561823 reverse thiosulfate sulfurtransferase GlpE b3425 ECK120000387 glpD b3426 3562013 3563518 forward aerobic glycerol 3-phosphate dehydrogenase 10633102, b3426 ECK120004294 yzgL b3427 3563724 3564005 reverse putative uncharacterized protein YzgL b3427 ECK120000373 glgP b3428 3564134 3566581 reverse glycogen phosphorylase b3428 ECK120000370 glgA b3429 3566600 3568033 reverse glycogen synthase b3429 ECK120000372 glgC b3430 3568033 3569328 reverse glucose-1-phosphate adenylyltransferase 23648478,23878244,25607991, b3430 ECK120000374 glgX b3431 3569346 3571319 reverse limit dextrin α-1,6-glucohydrolase b3431 ECK120000371 glgB b3432 3571316 3573502 reverse 1,4-α-glucan branching enzyme 11807277,21421758, b3432 ECK125286406 yhgO b4788 3573660 3573701 reverse protein YhgO b4788 ECK125286419 yhgP b4789 3573679 3573708 reverse protein YhgP 34662240, b4789 ECK120000084 asd b3433 3573775 3574878 reverse aspartate-semialdehyde dehydrogenase b3433 ECK120004295 yhgN b3434 3575071 3575664 forward MarC family putative inner membrane protein YhgN b3434 ECK120002343 gntU b4476 3575721 3577061 reverse low-affinity gluconate transporter b3435,b3436,b4476 ECK120002341 gntK b3437 3577065 3577592 reverse D-gluconate kinase, thermostable 8655507, b3437 ECK120002342 gntR b3438 3577731 3578726 reverse DNA-binding transcriptional repressor GntR [EXP|W|Inferred from experiment] 4574690,8655507, Weak b3438 ECK120004296 yhhW b3439 3578950 3579645 reverse quercetin 2,3-dioxygenase 17639604, b3439 ECK120004297 yhhX b3440 3579768 3580805 reverse putative oxidoreductase YhhX 24391520, b3440 ECK120002584 ryhB b4451 3580922 3581016 reverse small regulatory RNA RyhB [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 11917098,12069726,14617150,19541626,22083717,22096151,23671689,26637361,27085802,27651365,27757702,28119418,30107543,30287822,30700509,31002843,32209682,33748186, Weak b4451 ECK120004298 yhhY b3441 3581138 3581626 forward -acetyltransferase YhhY [EXP-IDA|W|Inferred from direct assay] 25002546, Weak b3441 ECK120004299 yhhZ b3442 3581863 3583041 forward putative endonuclease YhhZ b3442 ECK120023916 insAB6 3583483 3584180 forward InsAB' transposase ECK120004301 insA6 b3444 3583483 3583758 forward IS1 protein InsA b3444 ECK120004302 insB6 b3445 3583677 3584180 forward IS1 protein InsB b3445 ECK120030086 yrhD b4612 3584404 3584559 forward uncharacterized protein YrhD b4612 ECK120004303 yrhB b3446 3584759 3585043 forward putative heat shock chaperone [IC|W|Inferred by curator] Weak b3446 ECK120000367 ggt b3447 3585081 3586823 reverse glutathione hydrolase proenzyme 11552267,12418234,15466585,17260973,17970276,18036555,18555071,18720502,19788059,1981661,23391932,2571648,26370226,2892489,33112625,33897647,7903400,8864839, b3447 ECK120001166 yhhA b3448 3586943 3587383 forward DUF2756 domain-containing protein YhhA 20001701, b3448 ECK120001039 ugpQ b3449 3587370 3588113 reverse glycerophosphodiester phosphodiesterase UgpQ 1851953, b3449 ECK120001037 ugpC b3450 3588110 3589180 reverse -glycerol 3-phosphate ABC transporter ATP binding subunit b3450 ECK120001038 ugpE b3451 3589182 3590027 reverse -glycerol 3-phosphate ABC transporter membrane subunit UgpE b3451 ECK120001035 ugpA b3452 3590024 3590911 reverse -glycerol 3-phosphate ABC transporter membrane subunit UgpA b3452 ECK120001036 ugpB b3453 3591009 3592325 reverse -glycerol 3-phosphate ABC transporter periplasmic binding protein 31438868, b3453 ECK120000529 livF b3454 3592724 3593437 reverse branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF b3454 ECK120000530 livG b3455 3593439 3594206 reverse branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG b3455 ECK120000534 livM b3456 3594203 3595480 reverse branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM 2993238,31438868, b3456 ECK120000531 livH b3457 3595477 3596403 reverse branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH b3457 ECK120000533 livK b3458 3596451 3597560 reverse L-leucine/L-phenylalanine ABC transporter periplasmic binding protein 12538904,1757475,2007577,32518189,4077929,4908543,6381513, b3458 ECK120002098 panZ b3459 3597984 3598367 forward PanD maturation factor [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 2195019,23170229,25048226,26276430, Weak b3459 ECK120000532 livJ b3460 3598555 3599658 reverse branched chain amino acid/phenylalanine ABC transporter periplasmic binding protein 2195019,4077929, b3460 ECK120000888 rpoH b3461 3599929 3600783 reverse RNA polymerase sigma factor RpoH [EXP-IDA|W|Inferred from direct assay],[EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10903518,1565647,21353626,22496372,2695391,27240201,3550388,6092838,6337122,6380765,6387714,7038687, Strong b3461 ECK120000339 ftsX b3462 3601028 3602086 reverse cell division protein FtsX 10048040,1379670,3025556,3323846,6394955, b3462 ECK120000334 ftsE b3463 3602079 3602747 reverse cell division protein FtsE 33320186, b3463 ECK120000340 ftsY b3464 3602750 3604243 reverse signal recognition particle receptor [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 17726013,18617187,19174514,19469550,20146389,21898651,26459600,29967439,8107852,9326611, Strong b3464 ECK120000337 rsmD b3465 3604393 3604989 forward 16S rRNA mG966 methyltransferase b3465 ECK120002099 yhhL b3466 3604979 3605248 forward DUF1145 domain-containing protein YhhL b3466 ECK120002100 yhhM b3467 3605251 3605610 reverse DUF2500 domain-containing protein YhhM b3467 ECK120002101 yhhN b3468 3605751 3606377 forward PF07947 family protein YhhN 24391520, b3468 ECK120002102 zntA b3469 3606451 3608649 forward Zn exporting P-type ATPase 10529259,10964935,11412123,11527979,11874474,14510639,16159766,16411752,24350798,31461510,31974311, b3469 ECK120002103 tusA b3470 3608751 3608996 reverse sulfur transfer protein TusA [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 16387657, Weak b3470 ECK120002104 yhhQ b3471 3609217 3609882 forward queuosine precursor transporter b3471 ECK120004304 dcrB b3472 3609955 3610512 forward periplasmic bacteriophage sensitivity protein DcrB b3472 ECK120002105 yhhS b3473 3610516 3611733 reverse putative transporter YhhS b3473 ECK120002106 yhhT b3474 3611865 3612914 forward putative transporter YhhT 31438868, b3474 ECK120002107 acpT b3475 3612969 3613556 forward holo-[acyl carrier protein] synthase 2 b3475 ECK120001981 nikA b3476 3613667 3615241 forward Ni(2+) ABC transporter periplasmic binding protein 17242515, b3476 ECK120001982 nikB b3477 3615241 3616185 forward Ni(2+) ABC transporter membrane subunit NikB b3477 ECK120001983 nikC b3478 3616182 3617015 forward Ni(2+) ABC transporter membrane subunit NikC b3478 ECK120001984 nikD b3479 3617015 3617779 forward Ni(2+) ABC transporter ATP binding subunit NikD 31438868, b3479 ECK120001985 nikE b3480 3617776 3618582 forward Ni(2+) ABC transporter ATP binding subunit NikE b3480 ECK120001473 nikR b3481 3618588 3618989 forward DNA-binding transcriptional repressor NikR 10787413,9882686, b3481 ECK120000838 rhsB b3482 3619192 3623427 forward rhs element protein RhsB 6086936, b3482 ECK120001474 yhhH b3483 3623399 3623782 forward PF15631 family protein YhhH b3483 ECK120026454 yrhC b4552 3623887 3624132 forward b4552 ECK120001479 yhhI b3484 3624378 3625514 forward putative transposase b3484 ECK120001703 yhhJ b3485 3625679 3626803 reverse ABC transporter family protein YhhJ 18634750,31438868, b3485 ECK120002108 rbbA b3486 3626803 3629538 reverse ribosome-associated ATPase [EXP-IGI|W|Inferred from genetic interaction] 11544226,11566977,21556145, Weak b3486 ECK120002109 yhiI b3487 3629535 3630602 reverse putative membrane fusion protein YhiI b3487 ECK125286393 yhiY b4790 3630665 3630778 reverse protein YhiY 30837344, b4790 ECK120002110 yhiJ b3488 3630968 3632590 reverse DUF4049 domain-containing protein YhiJ b3488 ECK120002112 yhiL b4660 3632852 3634458 reverse DUF4049 domain-containing protein YhiL b3489,b3490,b4660 ECK120016281 yhiM b3491 3634841 3635893 forward inner membrane protein YhiM [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 12426343,22327802,9230301, Weak b3491 ECK120002113 yhiN b3492 3636208 3637410 reverse putative oxidoreductase YhiN 25091064, b3492 ECK120002114 pitA b3493 3637642 3639141 forward metal phosphate:H symporter PitA 179980,25645557,31438868, b3493 ECK120002115 uspB b3494 3639385 3639720 reverse universal stress protein B [EXP-IMP|W|Inferred from mutant phenotype] 11786251,20817623,9767572,9829921, Weak b3494 ECK120001357 uspA b3495 3640111 3640545 forward universal stress protein A b3495 ECK125286404 yriA b4791 3640612 3640686 reverse protein YriA b4791 ECK125286416 yriB b4792 3640643 3640696 reverse protein YriB b4792 ECK120002116 dtpB b3496 3640862 3642331 forward dipeptide/tripeptide:H symporter DtpB 27916534, b3496 ECK120002117 rsmJ b3497 3642380 3643132 reverse 16S rRNA mG1516 methyltransferase b3497 ECK120001405 prlC b3498 3643140 3645182 reverse oligopeptidase A [EXP|W|Inferred from experiment] 1325967,7691339, Weak b3498 ECK120002118 rlmJ b3499 3645385 3646227 forward 23S rRNA mA2030 methyltransferase 20719918, b3499 ECK120000405 gor b3500 3646299 3647651 forward glutathione reductase (NADPH) b3500 ECK120002670 dinQ b4613 3647705 3647788 reverse membrane toxin DinQ [EXP-IGI|W|Inferred from genetic interaction] 23408903,27651528, Weak b4613 ECK125158033 agrA b4712 3648063 3648144 forward small RNA AgrA 27651528, b4712 ECK125158035 agrB b4713 3648294 3648375 forward small regulatory RNA AgrB [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 23408903,27651528, Weak b4713 ECK120002119 arsR b3501 3648528 3648881 forward DNA-binding transcriptional repressor ArsR b3501 ECK120002120 arsB b3502 3648935 3650224 forward arsenite/antimonite:H antiporter b3502 ECK120002121 arsC b3503 3650237 3650662 forward arsenate reductase 19484295,24464705, b3503 ECK120004305 insH11 b3505 3652182 3653162 reverse IS transposase and trans-activator b3505 ECK120001820 slp b3506 3653961 3654527 forward starvation lipoprotein 32053772,8022277, b3506 ECK120001819 dctR b3507 3654683 3655213 forward putative DNA-binding transcriptional regulator DctR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 15556475,17259322,29718935,9811641, Weak b3507 ECK120001366 yhiD b3508 3655255 3655902 reverse inner membrane protein YhiD b3508 ECK120001365 hdeB b3509 3655966 3656292 reverse periplasmic acid stress chaperone HdeB b3509 ECK120001364 hdeA b3510 3656408 3656740 reverse periplasmic acid stress chaperone HdeA 10318909,10450164,12057949,12657056,12694615,23738772,23867204,24375557,7854117,8244952,9731767, b3510 ECK120001451 hdeD b3511 3656995 3657567 forward acid-resistance membrane protein [EXP-IGI|W|Inferred from genetic interaction] 12694615, Weak b3511 ECK125135001 arrS b4704 3657985 3658054 reverse small regulatory RNA ArrS [EXP-IMP|W|Inferred from mutant phenotype] 24600026, Weak b4704 ECK120001498 gadE b3512 3658366 3658893 forward DNA-binding transcriptional activator GadE [EXP|W|Inferred from experiment] 12399493,12426343,12657056,12694615,12704134,12940989,14702398,30578262,32094588, Weak b3512 ECK125242747 gadF b4718 3658992 3659082 forward small regulatory RNA GadF [EXP-IMP|W|Inferred from mutant phenotype] 27588604, Weak b4718 ECK120002123 mdtE b3513 3659232 3660389 forward multidrug efflux pump membrane fusion protein MdtE 12949086,31438868,32053772, b3513 ECK120002124 mdtF b3514 3660414 3663527 forward multidrug efflux pump RND permease MdtF 17062614,27050393,31251753, b3514 ECK120002125 gadW b3515 3663890 3664618 reverse DNA-binding transcriptional dual regulator GadW [EXP|W|Inferred from experiment],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 12446650, Weak b3515 ECK120002624 gadY b4452 3664864 3664969 forward small regulatory RNA GadY [EXP-IDA|W|Inferred from direct assay],[EXP-IEP|W|Inferred from expression pattern] 15466020,21147125,21314918,31186337, Weak b4452 ECK120002126 gadX b3516 3664986 3665810 reverse DNA-binding transcriptional dual regulator GadX [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 11976288,12446650, Weak b3516 ECK120002568 gadA b3517 3666180 3667580 reverse glutamate decarboxylase A 10383761,1522060,32346014,7608084, b3517 ECK120002127 ccp b3518 3667791 3669188 reverse cytochrome peroxidase 16377617, b3518 ECK120002128 treF b3519 3669592 3671241 forward cytoplasmic trehalase 10816581, b3519 ECK120002129 yhjB b3520 3671292 3671894 reverse putative DNA-binding transcriptional regulator YhjB [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b3520 ECK120002130 rcdB b3521 3672414 3673313 forward putative DNA-binding transcriptional regulator YhjC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b3521 ECK120002131 yhjD b3522 3673362 3674375 forward putative transporter YhjD [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IPI|W|Inferred from physical interaction],[EXP-IGI|W|Inferred from genetic interaction] 18093093,22125496,27732863, Weak b3522 ECK120002132 yhjE b3523 3674786 3676108 forward putative transporter YhjE 31438868, b3523 ECK120002133 yhjG b3524 3676290 3678350 reverse AsmA family protein YhjG b3524 ECK120002134 pdeH b3525 3678420 3679187 reverse c-di-GMP phosphodiesterase PdeH 20346719,24981318,26553851, b3525 ECK120002135 kdgK b3526 3679419 3680348 forward 2-dehydro-3-deoxygluconokinase b3526 ECK120002136 yhjJ b3527 3680444 3681940 reverse peptidase M16 family protein YhjJ 30909843, b3527 ECK120002437 dctA b3528 3682161 3683447 reverse C4 dicarboxylate/orotate:H symporter 31438868,34203512,4568614, b3528 ECK120002137 pdeK b3529 3683630 3685618 reverse c-di-GMP phosphodiesterase PdeK b3529 ECK120002138 bcsC b3530 3685700 3689173 reverse cellulose synthase outer membrane channel 29234007, b3530 ECK120002139 bcsZ b3531 3689155 3690261 reverse endo-1,4-D-glucanase 24127606,29234007,31604608, b3531 ECK120002140 bcsB b3532 3690268 3692607 reverse cellulose synthase periplasmic subunit 27510400,31604608,32534064, b3532 ECK120002141 bcsA b3533 3692618 3695236 reverse cellulose synthase catalytic subunit [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 11260463,17384304,18599830,32534064, Weak b3533 ECK120002142 bcsQ b3534 3695233 3695985 reverse cellulose biosynthesis protein b3534 ECK120002143 yhjR b3535 3695997 3696185 reverse PF10945 family protein YhjR b3535 ECK120002144 bcsE b3536 3696458 3698029 forward c-di-GMP-binding protein BcsE 24942809,31604608, b3536 ECK120002145 bcsF b3537 3698026 3698217 forward putative cellulose biosynthesis protein BcsF 31604608, b3537 ECK120002146 bcsG b3538 3698214 3699893 forward cellulose phosphoethanolamine transferase 11929533,31604608, b3538 ECK120002626 ldrD b4453 3699980 3700087 reverse small toxic polypeptide LdrD [EXP-IMP|W|Inferred from mutant phenotype] 12123448,18710431,32518184, Weak b4453 ECK120002627 rdlD b4454 3700136 3700199 forward antisense regulatory RNA RdlD [EXP-IMP|W|Inferred from mutant phenotype] 12123448,15718303,32518184, Weak b4454 ECK120002147 yhjV b3539 3700563 3701834 forward putative transporter YhjV 31438868,33406033, b3539 ECK120002340 dppF b3540 3701864 3702868 reverse dipeptide ABC transporter ATP binding subunit DppF 27718375, b3540 ECK120002339 dppD b3541 3702865 3703848 reverse dipeptide ABC transporter ATP binding subunit DppD 31438868, b3541 ECK120002338 dppC b3542 3703859 3704761 reverse dipeptide ABC transporter membrane subunit DppC 31438868, b3542 ECK120002337 dppB b3543 3704771 3705790 reverse dipeptide ABC transporter membrane subunit DppB b3543 ECK120000242 dppA b3544 3706098 3707705 reverse dipeptide ABC transporter periplasmic binding protein 14342337,29728377,34611772,8336670, b3544 ECK120002508 proK b3545 3708616 3708692 reverse tRNA-Pro(CGG) [AS-TAS|W|Traceable author statement] 27288443,7033244, Weak b3545 ECK120002148 eptB b3546 3708784 3710475 reverse phosphoethanolamine transferase EptB 30654491,33460557, b3546 ECK120002149 yhjX b3547 3710799 3712007 reverse putative transporter YhjX [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern] 23222720,24659770,31191496,31438868,33260635,9529885, Weak b3547 ECK120002150 yhjY b3548 3712236 3712934 reverse putative outer membrane protein YhjY 16522795, b3548 ECK120000975 tag b3549 3713092 3713655 forward 3-methyl-adenine DNA glycosylase I, constitutive 30617079, b3549 ECK120002151 yiaC b3550 3713652 3714092 forward peptidyl-lysine -acetyltransferase YiaC b3550 ECK120000120 bisC b3551 3714061 3716394 reverse biotin sulfoxide reductase b3551 ECK120002152 yiaD b3552 3716547 3717206 forward PF13488 family lipoprotein YiaD 32053772, b3552 ECK120002153 ghrB b3553 3717310 3718284 forward glyoxylate reductase b3553 ECK120002154 yiaF b3554 3718334 3719044 reverse DUF3053 domain-containing protein YiaF b3554 ECK120002336 yiaG b3555 3719478 3719768 forward putative DNA-binding transcriptional regulator YiaG 24391520, b3555 ECK120000162 cspA b3556 3720049 3720261 forward cold shock protein CspA [EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 19486664,1961761,28334975,32753505,3553157,8995247, Weak b3556 ECK125286391 ysaE b4793 3720400 3720471 forward protein YsaE b4793 ECK120002664 hokA b4455 3720448 3720600 reverse small toxic polypeptide [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern] 10361310, Weak b4455 ECK125240976 mokA b4647 3720448 3720632 reverse b4647 ECK120034531 insJK 3720680 3722049 forward IS150 protein InsAB [EXP-IMP|W|Inferred from mutant phenotype] 12374815, Weak ECK120004306 insJ b3557 3720680 3721201 forward insertion element IS150 protein InsA [EXP-IMP|W|Inferred from mutant phenotype] 12374815, Weak b3557 ECK120004307 insK b3558 3721198 3722049 forward IS150 conserved protein InsB b3558 ECK120030087 sokA b4614 3722077 3722111 forward b4614 ECK120000403 glyS b3559 3722328 3724397 reverse glycine—tRNA ligase subunit β 23770902, b3559 ECK120000402 glyQ b3560 3724407 3725318 reverse glycine—tRNA ligase subunit α 9286857, b3560 ECK120016319 ysaB b4553 3725413 3725712 reverse putative lipoprotein YsaB 32053772, b4553 ECK120002155 wecH b3561 3725887 3726882 forward -acetyltransferase WecH [EXP-IMP|W|Inferred from mutant phenotype] 16936038, Weak b3561 ECK120001167 yiaA b3562 3726924 3727361 reverse PF05360 family inner membrane protein YiaA 17456747, b3562 ECK120001241 yiaB b3563 3727407 3727748 reverse PF05360 family inner membrane protein YiaB b3563 ECK120001064 xylB b3564 3727917 3729371 reverse xylulokinase 1323828,2853882,6282416,6320721,6330500,6344793, b3564 ECK125303721 xylZ b4834 3729386 3729545 reverse small RNA XylZ b4834 ECK120001063 xylA b3565 3729443 3730765 reverse xylose isomerase 11325924,12407454,15841369,16243589,16672486,16878542,17662053,18304345,18586973,18828178,19235507,20568206,2132127,2176792,22691294,23850830,26045332,26336892,2823706,28756856,29374483,3305172,3919721,4604054,4908641,6282416, b3565 ECK120002448 xylF b3566 3731131 3732123 forward xylose ABC transporter periplasmic binding protein 24161920,26279676,27274356, b3566 ECK120002156 xylG b3567 3732201 3733742 forward xylose ABC transporter ATP binding subunit b3567 ECK120002157 xylH b3568 3733720 3734901 forward xylose ABC transporter membrane subunit b3568 ECK120002449 xylR b3569 3734979 3736157 forward DNA-binding transcriptional dual regulator XylR b3569 ECK120001329 bax b3570 3736353 3737177 reverse putative glycoside hydrolase Bax b3570 ECK125286388 baxL b4794 3737177 3737203 reverse putative translational regulatory protein BaxL [EXP-IMP|W|Inferred from mutant phenotype] 30837344, Weak b4794 ECK120001287 malS b3571 3737497 3739527 forward α-amylase b3571 ECK120000103 avtA b3572 3739705 3740958 forward valine—pyruvate aminotransferase 12557311,1646790,23831557,2825136,2890623,3044925,411384, b3572 ECK120002158 ysaA b3573 3741109 3741582 reverse putative electron transport protein YsaA b3573 ECK120002159 plaR b3574 3741684 3742532 reverse DNA-binding transcriptional repressor PlaR [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IPI|W|Inferred from physical interaction],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 10913096,30137486,9525947, Weak b3574 ECK120002160 yiaK b3575 3742733 3743731 forward 2,3-diketo-L-gulonate reductase b3575 ECK120002161 yiaL b3576 3743743 3744210 forward DUF386 domain-containing protein YiaL b3576 ECK120002162 yiaM b3577 3744328 3744801 forward 2,3-diketo-L-gulonate:Na symporter - membrane subunit 31438868, b3577 ECK120002163 yiaN b3578 3744804 3746081 forward 2,3-diketo-L-gulonate:Na symporter - membrane subunit b3578 ECK120002164 yiaO b3579 3746094 3747080 forward 2,3-diketo-L-gulonate:Na symporter - periplasmic binding protein b3579 ECK120002165 lyxK b3580 3747084 3748580 forward L-xylulose kinase 10913097,11741871,28859803, b3580 ECK120002166 sgbH b3581 3748577 3749239 forward 3-keto-L-gulonate-6-phosphate decarboxylase SgbH b3581 ECK120002167 sgbU b3582 3749232 3750092 forward putative L-xylulose 5-phosphate 3-epimerase 10913097, b3582 ECK120002168 sgbE b3583 3750086 3750781 forward L-ribulose-5-phosphate 4-epimerase SgbE 10913097, b3583 ECK125240977 ysaC b4648 3750813 3750914 reverse b4648 ECK125240978 ysaD b4649 3750918 3751109 forward b4649 ECK120002169 yiaT b3584 3751128 3751868 reverse outer membrane protein YiaT b3584 ECK120002170 yiaU b3585 3751992 3752966 forward putative DNA-binding transcriptional regulator YiaU [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b3585 ECK120002171 yiaV b3586 3752963 3754099 reverse putative membrane fusion protein YiaV b3586 ECK120002172 yiaW b3587 3754105 3754428 reverse DUF3302 domain-containing protein YiaW b3587 ECK120002173 aldB b3588 3754973 3756511 reverse aldehyde dehydrogenase B 7768815, b3588 ECK120002174 yiaY b3589 3756676 3757827 reverse L-threonine dehydrogenase 22731523,24391520,7548, b3589 ECK120000931 selB b3590 3758017 3759861 reverse selenocysteyl-tRNA-specific translation elongation factor [EXP-IMP|W|Inferred from mutant phenotype] 22246579,23982514,2524495,28193838, Weak b3590 ECK120000930 selA b3591 3759858 3761249 reverse selenocysteine synthase b3591 ECK120001698 yibF b3592 3761347 3761955 reverse glutathione transferase-like protein YibF [COMP-HINF|W|Inferred by a human based on computational evidence] 14635120, Weak b3592 ECK120000837 rhsA b3593 3762183 3766316 forward rhs element protein RhsA [EXP-IMP|W|Inferred from mutant phenotype] 6086936,7721712, Weak b3593 ECK120001168 yibA b3594 3766337 3767179 forward putative lyase containing HEAT-repeat [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 16397293,22731697, Weak b3594 ECK120001702 yibJ b3595 3767221 3767922 forward putative RHS domain-containing protein YibJ b3595 ECK120001699 yibG b3596 3768177 3768638 forward tetratricopeptide-like domain-containing protein YibG b3596 ECK125240979 yibS b4650 3768639 3768890 forward RHS family protein YibS b4650 ECK125240980 yibW b4651 3768892 3769256 forward b4651 ECK120030088 yibV b4615 3769345 3769680 forward PF15596 family protein YibV b4615 ECK125240981 yibU b4652 3769948 3770146 forward b4652 ECK120001700 yibH b3597 3770243 3771379 reverse inner membrane protein YibH b3597 ECK120001701 yibI b3598 3771382 3771744 reverse DUF3302 domain-containing protein YibI b3598 ECK120000608 mtlA b3599 3772281 3774194 forward mannitol-specific PTS enzyme IICBA component b3599 ECK120000609 mtlD b3600 3774424 3775572 forward mannitol-1-phosphate 5-dehydrogenase 24908186,3135464,4563979,6201477,6401703,6425270, b3600 ECK120001891 mtlR b3601 3775572 3776159 forward transcriptional repressor MtlR [EXP-IMP|W|Inferred from mutant phenotype] 1964486,28225088,8041620,8300537, Weak b3601 ECK120016320 yibT b4554 3776171 3776380 reverse protein YibT 28553265, b4554 ECK120001890 yibL b3602 3776665 3777027 forward DUF2810 domain-containing protein YibL b3602 ECK120001887 lldP b3603 3777399 3779054 forward lactate/glycolate:H symporter LldP 8759842, b3603 ECK120001888 lldR b3604 3779054 3779830 forward DNA-binding transcriptional dual regulator LldR [EXP-IDA|W|Inferred from direct assay] 18263722,8759842, Weak b3604 ECK120001889 lldD b3605 3779827 3781017 forward L-lactate dehydrogenase b3605 ECK120001818 trmL b3606 3781215 3781688 forward tRNA (cytidine/uridine-2'-)-ribose methyltransferase b3606 ECK120000182 cysE b3607 3781741 3782562 reverse serine acetyltransferase b3607 ECK120002442 gpsA b3608 3782642 3783661 reverse glycerol-3-phosphate dehydrogenase b3608 ECK120000926 secB b3609 3783661 3784128 reverse protein export chaperone SecB b3609 ECK120002175 grxC b3610 3784191 3784442 reverse reduced glutaredoxin 3 [EXP|W|Inferred from experiment] 25350574,9111025,9188456, Weak b3610 ECK120002176 yibN b3611 3784584 3785015 reverse putative sulfurtransferase YibN b3611 ECK120002177 gpmM b3612 3785260 3786804 forward 2,3-bisphosphoglycerate-independent phosphoglycerate mutase b3612 ECK120002178 envC b3613 3786838 3788097 forward murein hydrolase activator EnvC [EXP|W|Inferred from experiment] 15165230,22006326,27718375,318637,352222,378695,3890689,4218460,4574921,6120994,6384425, Weak b3613 ECK120002179 yibQ b3614 3788101 3789060 forward divergent polysaccharide deacetylase domain-containing protein YibQ [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 12952533, Weak b3614 ECK120001240 waaH b3615 3789047 3790081 reverse UDP-glucuronate:LPS(HepIII) glycosyltransferase 15659689, b3615 ECK120000982 tdh b3616 3790320 3791345 reverse threonine dehydrogenase 3531182,7748928, b3616 ECK120000505 kbl b3617 3791355 3792551 reverse 2-amino-3-ketobutyrate CoA ligase 1917830,3287333, b3617 ECK120001169 htrL b3618 3792826 3793683 reverse protein HtrL b3618 ECK120000829 rfaD b3619 3793987 3794919 forward ADP-L-glycero-D-mannoheptose 6-epimerase b3619 ECK120002097 waaF b3620 3794929 3795975 forward ADP-heptose—LPS heptosyltransferase 2 1577693,1938935,3882666,7854127,9266718, b3620 ECK120001170 waaC b3621 3795979 3796938 forward ADP-heptose:LPS heptosyltransferase 1 b3621 ECK120001388 waaL b3622 3796948 3798207 forward O-antigen ligase 10574995,57114, b3622 ECK125286402 yibX b4795 3797772 3798014 reverse protein YibX-S b4795 ECK125286402 yibX b4795 3797772 3798014 reverse protein YibX b4795 ECK125286413 yibY b4796 3798039 3798149 reverse protein YibY b4796 ECK120001387 waaU b3623 3798239 3799312 reverse putative ADP-heptose:LPS heptosyltransferase 4 b3623 ECK120001390 waaZ b3624 3799345 3800196 reverse lipopolysaccharide core biosynthesis protein WaaZ b3624 ECK120001389 waaY b3625 3800267 3800965 reverse lipopolysaccharide core heptose (II) kinase 1385388,1577693,26023839,27002133, b3625 ECK120001322 waaJ b3626 3800983 3801999 reverse UDP-glucose:(glucosyl)LPS α-1,2-glucosyltransferase 1348243, b3626 ECK120001321 waaO b3627 3802039 3803058 reverse UDP-D-glucose:(glucosyl)LPS α-1,3-glucosyltransferase b3627 ECK120001320 waaB b3628 3803058 3804137 reverse UDP-D-galactose:(glucosyl)lipopolysaccharide-1,6-D-galactosyltransferase b3628 ECK120001319 waaS b3629 3804181 3805116 reverse lipopolysaccharide core biosynthesis protein WaaS [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 1385388,1624461, Weak b3629 ECK120001311 waaP b3630 3805153 3805950 reverse lipopolysaccharide core heptose (I) kinase 1385388,1577693,2168379,26023839,27002133,28553265, b3630 ECK120001310 waaG b3631 3805943 3807067 reverse lipopolysaccharide glucosyltransferase I b3631 ECK120001312 waaQ b3632 3807064 3808098 reverse lipopolysaccharide core heptosyltransferase 3 1348243,1385388,1577693,16209909,1655711,19364804,1938935,23985204,25631507,7988890, b3632 ECK125240975 rirA b4760 3808166 3808238 reverse small regulatory RNA RirA [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IPI|W|Inferred from physical interaction] 27629414, Weak b4760 ECK120000513 waaA b3633 3808540 3809817 forward KDO transferase b3633 ECK120001171 coaD b3634 3809825 3810304 forward pantetheine-phosphate adenylyltransferase 20486930,23550886,29243909, b3634 ECK120000323 mutM b3635 3810343 3811152 reverse DNA-formamidopyrimidine glycosylase 10563580,1378443,14637251,14692765,14769949,15979229,16928690,16953574,17536801,18557781,19835417,20118965,21561236,22175854,22584623,22732937,25415645,27903453,28482831,29320630,30617079,33573045, b3635 ECK120000882 rpmG b3636 3811250 3811417 reverse 50S ribosomal subunit protein L33 10445875,1089427,1092342,2211695,22821559,29551268,327280,3289545,3298242,3315664,340794,3886833,4616944,6209544,6349991,6361486,6386476,6450866,6450872,7035835,7047160,765132,791272,793594,8031879, b3636 ECK120000877 rpmB b3637 3811438 3811674 reverse 50S ribosomal subunit protein L28 1092342,109811,1100375,2211695,29551268,3298242,332524,340794,387748,3886833,6338479,6361486,6386476,6450866,6450872,68433,7035835,7685806,781624,791272, b3637 ECK120001283 yicR b3638 3811891 3812559 reverse RadC-like JAB domain-containing protein YicR 10224240,11489855,16710451,17068078,1741263,3331954,3517933,6374741, b3638 ECK120000004 dfp b3639 3812731 3813951 forward fused 4'-phosphopantothenoylcysteine decarboxylase and phosphopantothenoylcysteine synthetase 10922366,11804498,15530362,23472115,3123465,31488574, b3639 ECK120000245 dut b3640 3813929 3814387 forward dUTP diphosphatase b3640 ECK120001172 slmA b3641 3814494 3815090 forward nucleoid occlusion factor SlmA b3641 ECK120000799 pyrE b3642 3815127 3815768 reverse orotate phosphoribosyltransferase b3642 ECK120000854 rph b3643 3815863 3816549 reverse truncated RNase PH 28625967, b3643 ECK120001173 yicC b3644 3816676 3817539 forward putative RNase adaptor protein YicC [EXP-IMP|W|Inferred from mutant phenotype] 34210798, Weak b3644 ECK120001174 dinD b3645 3817760 3818584 forward DNA damage-inducible protein D [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 10398829,11443091,6771759,6818350,7029544,8002613,8682790, Weak b3645 ECK120001626 yicG b3646 3818874 3819491 forward PF03458 family inner membrane protein YicG 31438868, b3646 ECK120001305 ligB b3647 3819488 3821170 reverse DNA ligase B 11812821, b3647 ECK120000954 gmk b3648 3821428 3822051 forward guanylate kinase b3648 ECK120000890 rpoZ b3649 3822106 3822381 forward RNA polymerase subunit ω [EXP|W|Inferred from experiment] 2646273,3549461, Weak b3649 ECK120000955 spoT b3650 3822400 3824508 forward bifunctional (p)ppGpp synthase/hydrolase SpoT 374338, b3650 ECK120000956 trmH b3651 3824515 3825204 forward tRNA (Gm18) 2'--methyltransferase 12427942,8871555, b3651 ECK120000820 recG b3652 3825210 3827291 forward ATP-dependent DNA helicase RecG [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 19657385,25368150,33382157,7957087,8428576, Strong b3652 ECK120000399 gltS b3653 3827460 3828665 reverse glutamate:sodium symporter b3653 ECK120001175 xanP b3654 3828945 3830336 forward xanthine:H symporter XanP b3654 ECK120001627 yicH b3655 3830457 3832166 forward AsmA family protein YicH b3655 ECK120001628 yicI b3656 3832219 3834537 reverse α-D-xyloside xylohydrolase b3656 ECK120001629 yicJ b3657 3834547 3835929 reverse putative xyloside transporter YicJ 31438868, b3657 ECK120002534 selC b3658 3836222 3836316 forward tRNA-Sec(UCA) [AS-TAS|W|Traceable author statement] 7033244, Weak b3658 ECK125240982 yicT b4653 3836425 3836556 forward b4653 ECK120001630 setC b3659 3836953 3838137 forward putative arabinose exporter b3659 ECK120001631 yicL b3660 3838248 3839171 forward putative transporter YicL 31438868, b3660 ECK125286389 yicU b4797 3838642 3838701 reverse protein YicU b4797 ECK120000650 nlpA b3661 3839175 3839993 reverse lipoprotein-28 32053772, b3661 ECK120016321 yicS b4555 3840215 3840508 forward uncharacterized protein YicS 28553265, b4555 ECK120001632 nepI b3662 3840549 3841739 reverse purine ribonucleoside exporter b3662 ECK120001633 yicN b3663 3841950 3842402 reverse DUF1198 domain-containing protein YicN b3663 ECK120001634 adeQ b3664 3842455 3843789 reverse adenine transporter b3664 ECK120001635 adeD b3665 3843964 3845730 forward adenine deaminase 16041126, b3665 ECK125303709 uhpU b4829 3845730 3845995 reverse small RNA UhpU b4829 ECK120001043 uhpT b3666 3845776 3847167 reverse hexose-6-phosphate:phosphate antiporter 206329,3038843,3283129,4905309,4928894,5336025,9837961, b3666 ECK120001042 uhpC b3667 3847305 3848624 reverse inner membrane protein sensing glucose-6-phosphate 8144492, b3667 ECK120001041 uhpB b3668 3848634 3850136 reverse sensory histidine kinase UhpB 11325944,12107138, b3668 ECK120001040 uhpA b3669 3850136 3850726 reverse DNA-binding transcriptional activator UhpA [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 10512697,10966457,11976297,1482126,1569007,1569008,2157156,3301805,7596290,7686882,7699720,8098993,8999880,9220010, Weak b3669 ECK120000495 ilvN b3670 3850802 3851092 reverse acetohydroxy acid synthase I subunit IlvN b3670 ECK120000487 ilvB b3671 3851096 3852784 reverse acetohydroxy acid synthase I subunit IlvB b3671 ECK120001249 ivbL b3672 3852890 3852988 reverse operon leader peptide [EXP-IDA|W|Inferred from direct assay] 28301469,6292893, Weak b3672 ECK120015143 istR-1 3853118 3853192 reverse ECK120015142 istR b4616 3853118 3853257 reverse small RNA IstR-2 [EXP|W|Inferred from experiment],[EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 11448770,15620655,17499044, Weak b4616 ECK120015142 istR b4616 3853118 3853257 reverse small regulatory RNA IstR-1 [EXP|W|Inferred from experiment],[EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 11448770,15620655,17499044, Weak b4616 ECK120002668 tisA b4617 3853443 3853556 forward b4617 ECK120002669 tisB b4618 3853553 3853642 forward membrane-depolarizing toxin TisB [EXP-IMP|W|Inferred from mutant phenotype] 15620655,20186264,27997707, Weak b4618 ECK125286401 ysdE b4798 3853766 3853840 reverse protein YsdE b4798 ECK120001636 emrD b3673 3853922 3855106 forward multidrug efflux pump EmrD 23959879,24148002,32379525,7721726, b3673 ECK120001637 yidF b3674 3855114 3855611 reverse uncharacterized protein YidF [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15556475, Weak b3674 ECK120001638 yidG b3675 3855608 3855970 reverse inner membrane protein YidG 17456747, b3675 ECK120001639 yidH b3676 3855960 3856307 reverse DUF202 domain-containing inner membrane protein YidH 25419869, b3676 ECK120001640 yidI b3677 3856415 3856864 forward putative inner membrane protein YidI b3677 ECK120001648 yidJ b3678 3856911 3858404 reverse putative sulfatase/phosphatase YidJ 8990283, b3678 ECK120001649 yidK b3679 3858401 3860116 reverse putative transporter YidK 28093455,31438868, b3679 ECK120001650 yidL b3680 3860283 3861176 forward putative DNA-binding transcriptional regulator YidL [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b3680 ECK120001651 glvG b4556 3861173 3861987 reverse b4556 ECK120001652 glvB b3682 3861987 3862472 reverse putative PTS enzyme II component GlvB [COMP-HINF-ISA|W|Inferred from Sequence Alignment] 3552873,8019415, Weak b3682 ECK120001653 glvC b3683 3862497 3863603 reverse putative PTS enzyme II component GlvC [COMP-HINF-ISA|W|Inferred from Sequence Alignment] 15755952,3552873,8019415, Weak b3683 ECK120001654 yidP b3684 3863899 3864615 forward putative DNA-binding transcriptional regulator YidP [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475,24391520, Weak b3684 ECK120001490 yidE b3685 3864612 3866273 reverse putative transport protein YidE 31438868, b3685 ECK120001489 ibpB b3686 3866469 3866897 reverse small heat shock protein IbpB b3686 ECK120001488 ibpA b3687 3867009 3867422 reverse small heat shock protein IbpA b3687 ECK120001655 yidQ b3688 3867728 3868060 forward DUF1375 domain-containing putative lipoprotein YidQ 32053772, b3688 ECK120001656 yidR b3689 3868062 3869309 reverse DUF3748 domain-containing galacturonate catabolism protein YidR [EXP-IMP|W|Inferred from mutant phenotype] 28093455, Weak b3689 ECK120001657 cbrA b3690 3869377 3870441 forward colicin M resistance protein [EXP-IMP|W|Inferred from mutant phenotype] 22773789, Weak b3690 ECK120002440 dgoT b3691 3870438 3871730 reverse D-galactonate:H symporter 7855594, b3691 ECK120004465 dgoD b4478 3871850 3872998 reverse D-galactonate dehydratase b3692,b4478 ECK120002438 dgoA b4477 3872995 3873612 reverse 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 17451239, b3692,b4477 ECK120002439 dgoK b3693 3873596 3874474 reverse 2-dehydro-3-deoxygalactonokinase b3693 ECK120004308 dgoR b4479 3874471 3875160 reverse DNA-binding transcriptional regulator DgoR b3694,b3695,b4479 ECK120001658 yidX b3696 3875438 3876094 forward putative lipoprotein YidX 32053772, b3696 ECK120001176 yidA b3697 3876140 3876952 reverse sugar phosphatase YidA b3697 ECK120001177 yidB b3698 3877067 3877465 reverse DUF937 domain-containing protein YidB 24391520, b3698 ECK120000417 gyrB b3699 3877705 3880119 reverse DNA gyrase subunit B b3699 ECK120000819 recF b3700 3880148 3881221 reverse recombination mediator protein RecF b3700 ECK120000236 dnaN b3701 3881221 3882321 reverse β sliding clamp 2851700,6458041, b3701 ECK120000229 dnaA b3702 3882326 3883729 reverse chromosomal replication initiator protein DnaA [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10497067,160412,27484197,33382157,337131,6296774,6310593,6327277,9125116, Strong b3702 ECK125276508 ysdD b4757 3884026 3884106 forward protein YsdD b4757 ECK120000883 rpmH b3703 3884336 3884476 forward 50S ribosomal subunit protein L34 1397490,160000,1714569,2211695,2415431,340794,6450872,68433,770189,783033,8088419,9371771, b3703 ECK120000853 rnpA b3704 3884493 3884852 forward RNase P protein component [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 2415431,29551268,386349,6164392, Weak b3704 ECK120016322 yidD b4557 3884816 3885073 forward membrane protein insertion efficiency factor [EXP-IMP|W|Inferred from mutant phenotype] 21803992, Weak b4557 ECK120001178 yidC b3705 3885076 3886722 forward membrane protein insertase YidC [EXP-IMP|W|Inferred from mutant phenotype],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10949305,11415985,11457858,11463745,11751917,11821048,12068816,12437136,12581356,12694185,12707259,12940994,12950181,14505821,14578344,15671040,17073462,17933892,18276587,18456666,18586516,18996118,19497329,21401071,22179606,23058713,23527078,23609445,23872420,26023232,28273911,29330529,30241934,30972527, Strong b3705 ECK120000986 mnmE b3706 3886828 3888192 forward 5-carboxymethylaminomethyluridine-tRNA synthase GTPase subunit 15616586,22575087,22750478,23874328,24785159,25731940,27535647, b3706 ECK120001250 tnaC b3707 3888435 3888509 forward operon leader peptide [EXP-IMP|W|Inferred from mutant phenotype] 10049385,15066794,18760284,19840930,2160052,2345136,24137004,28351917,28612351,29262826,30287822,31193188,8501042,8682777,9045840, Weak b3707 ECK120000994 tnaA b3708 3888730 3890145 forward tryptophanase 21145393,24203355,25913005,27638396,28612351,28979246,29164709,29171270,29216232,30382577,32346014,32351457,32503909,362170, b3708 ECK120000995 tnaB b3709 3890236 3891483 forward tryptophan:H symporter TnaB b3709 ECK120001659 mdtL b3710 3891615 3892790 forward efflux pump MdtL 31438868, b3710 ECK120001660 yidZ b3711 3892765 3893724 forward DNA-binding transcriptional dual regulator YidZ [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 10734204,15546870,15556475, Weak b3711 ECK120001661 yieE b3712 3893881 3894630 forward putative phosphopantetheinyl transferase b3712 ECK120001662 yieF b3713 3894652 3895218 forward quinone reductase 26016500, b3713 ECK120001663 adeP b3714 3895272 3896609 reverse adenine:H symporter b3714 ECK120001664 yieH b3715 3896774 3897439 forward 6-phosphogluconate phosphatase [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 15808744, Weak b3715 ECK120001665 cbrB b3716 3897506 3897973 forward putative inner membrane protein b3716 ECK120001666 cbrC b3717 3898022 3898609 forward PF03691 family colicin E2 tolerance protein CbrC [EXP-IMP|W|Inferred from mutant phenotype] 20418396, Weak b3717 ECK120001667 yieK b3718 3898671 3899393 reverse putative glucosamine-6-phosphate deaminase YieK [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 12952533, Weak b3718 ECK120001668 yieL b3719 3899408 3900577 reverse putative hydrolase YieL b3719 ECK120001333 bglH b3720 3900604 3902220 reverse carbohydrate-specific outer membrane porin, cryptic b3720 ECK120000110 bglB b3721 3902289 3903701 reverse 6-phospho-β-glucosidase B 4870648, b3721 ECK120000111 bglF b3722 3903720 3905597 reverse β-glucoside specific PTS enzyme II / BglG kinase / BglG phosphatase b3722 ECK120000112 bglG b3723 3905731 3906567 reverse transcriptional antiterminator BglG b3723 ECK120000726 phoU b3724 3906853 3907578 reverse negative regulator of the regulon b3724 ECK120000774 pstB b3725 3907593 3908366 reverse phosphate ABC transporter ATP binding subunit b3725 ECK120000773 pstA b3726 3908549 3909439 reverse phosphate ABC transporter membrane subunit PstA 1447208, b3726 ECK120000775 pstC b3727 3909439 3910398 reverse phosphate ABC transporter membrane subunit PstC 1447208, b3727 ECK120000725 pstS b3728 3910485 3911525 reverse phosphate ABC transporter periplasmic binding protein 179980,4599976, b3728 ECK120000375 glmS b3729 3911839 3913668 reverse L-glutamine—D-fructose-6-phosphate aminotransferase b3729 ECK120001179 glmU b3730 3913830 3915200 reverse fused N-acetylglucosamine-1-phosphate uridyltransferase and glucosamine-1-phosphate acetyltransferase b3730 ECK120000096 atpC b3731 3915553 3915972 reverse ATP synthase F complex subunit ε 15199054,161698,19411254,25228697,26589785,29769322,29932911,31438868,32194063,33128817,6444514,7583669,9331422,9756905, b3731 ECK120000097 atpD b3732 3915993 3917375 reverse ATP synthase F complex subunit β b3732 ECK120000100 atpG b3733 3917402 3918265 reverse ATP synthase F complex subunit γ 23893411,28553265,31251901, b3733 ECK120000094 atpA b3734 3918316 3919857 reverse ATP synthase F complex subunit α b3734 ECK120000101 atpH b3735 3919870 3920403 reverse ATP synthase F complex subunit δ 23864656, b3735 ECK120000099 atpF b3736 3920418 3920888 reverse ATP synthase F complex subunit b b3736 ECK120000098 atpE b3737 3920950 3921189 reverse ATP synthase F complex subunit c 25385585,28431927, b3737 ECK120000095 atpB b3738 3921236 3922051 reverse ATP synthase F complex subunit a 12021273,12525160,12525480,13679083,14990464,17234633,18786919,20943664,2145803,23864659,2528329,2536742,25385585,2891376,2896197,31438868,7982950,8383111,9632681, b3738 ECK120000102 atpI b3739 3922060 3922440 reverse ATP synthase accessory factor AtpI 1835698,2136739,21664273,6185823,6193096,6224772,8824597, b3739 ECK120000369 rsmG b3740 3923057 3923680 reverse 16S rRNA mG527 methyltransferase b3740 ECK120000368 mnmG b3741 3923744 3925633 reverse 5-carboxymethylaminomethyluridine-tRNA synthase subunit MnmG 20406421,22391092,27535647,27718375, b3741 ECK120001180 mioC b3742 3926012 3926455 reverse flavoprotein MioC 11244066,16298387,17316685, b3742 ECK120000089 asnC b3743 3926545 3927003 reverse DNA-binding transcriptional dual regulator AsnC 6357950,7686882, b3743 ECK120000087 asnA b3744 3927155 3928147 forward asparagine synthetase A 6117826, b3744 ECK120001669 viaA b3745 3928152 3929603 reverse protein ViaA [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 16301313,16855227, Weak b3745 ECK120001670 ravA b3746 3929597 3931093 reverse regulatory ATPase RavA b3746 ECK120001495 kup b3747 3931316 3933184 forward K symporter Kup 1987159, b3747 ECK120000808 rbsD b3748 3933351 3933770 forward D-ribose pyranase 23651393,26175201,3011793,9770507, b3748 ECK120000805 rbsA b3749 3933778 3935283 forward ribose ABC transporter ATP binding subunit b3749 ECK120000807 rbsC b3750 3935288 3936253 forward ribose ABC transporter membrane subunit 9922273, b3750 ECK120000806 rbsB b3751 3936278 3937168 forward ribose ABC transporter periplasmic binding protein 1328650,16157349,1644748,1848243,2179563,2254262,23698778,31438868,31729460,33682750,3928371,7563091,7982928,8050582,8157648,8830692,8878033, b3751 ECK125289862 rbsZ b4804 3937045 3937278 forward small regulatory RNA RbsZ [EXP-IMP|W|Inferred from mutant phenotype] 31761494, Weak b4804 ECK120000809 rbsK b3752 3937294 3938223 forward ribokinase 10393297,11373298,19124251,4909662,4909664,6746654, b3752 ECK120000810 rbsR b3753 3938227 3939219 forward DNA-binding transcriptional dual regulator RbsR [EXP|W|Inferred from experiment] 1304370,7686882, Weak b3753 ECK120001671 hsrA b3754 3939185 3940612 reverse putative transporter HsrA b3754 ECK120001672 yieP b3755 3940635 3941327 reverse DNA-binding transcriptional regulator YieP [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IPI|W|Inferred from physical interaction] 15556475,30137486,33149261, Weak b3755 ECK120002528 rrsC b3756 3941808 3943349 forward 16S ribosomal RNA 10753935,10844684,10919826,1094419,1101264,1102922,1103124,110460,11751827,12087167,12498,12902289,12903214,14510386,1646122,1716101,1718749,1764510,1764516,2145040,2168847,2222527,2387410,2435709,2443830,2448485,2473375,2685545,2689447,2833391,3013618,3071662,3071664,319193,320561,326259,327272,327273,3277949,331075,331313,3313279,3329282,342117,344139,348233,365689,378405,383432,384145,3894326,390405,392468,407931,4560773,4564202,4918356,4942898,4943519,6285294,6330033,6361011,6752954,6995826,7516168,7601845,769922,7718670,782716,782717,789334,793615,8041615,8312257,8377198,8419334,8515441,9034358,9226253,9501232,9769102, b3756 ECK120002475 gltU b3757 3943435 3943510 forward tRNA-Glu(UUC) [AS-TAS|W|Traceable author statement] 7033244, Weak b3757 ECK120002521 rrlC b3758 3943704 3946607 forward 23S ribosomal RNA [EXP-TAS|W|Traceable author statement to experimental support] 10051579,10464195,10525403,10793686,10844684,1094419,10964562,10986461,1098691,11157269,11350034,11517305,11574482,11675490,11680845,11741781,11751827,11888286,11955006,11991636,12022228,12034826,12467398,12498,12888505,1719209,1918155,2407189,3048270,3053641,3060850,3089782,319193,319197,3226909,325525,329865,359042,388189,3894326,390405,4563865,4584388,4918356,6158039,6162473,6170632,6193815,6349628,6361011,6750359,6996708,7016337,7041903,7514294,7529560,7567991,7682175,775291,785385,789334,791272,8031879,805122,8253085,8524828,8643399,8643630,8654409,8710862,8918803,9016593,9135982,9367788,9396814,9501232,9573162,9586034,9769102,9836593,9989214, Weak b3758 ECK120002514 rrfC b3759 3946700 3946819 forward 5S ribosomal RNA [EXP-TAS|W|Traceable author statement to experimental support] 11401702,11488615,164889,1709493,1709723,1718749,1764510,2190187,2412207,2493632,3013618,3089782,324975,327272,331075,3315008,342117,359042,4198187,4216514,4550693,4571522,4591367,4609878,4621557,4881049,4881332,4906324,4906608,4918254,4920877,4924729,4931952,4944480,4993318,6178431,6188537,6255417,6390428,6765232,7024913,782717,805122,810137,95791,9862991,9878392, Weak b3759 ECK120002466 aspT b3760 3946872 3946948 forward tRNA-Asp(GUC) [AS-TAS|W|Traceable author statement] 7033244, Weak b3760 ECK120002547 trpT b3761 3946957 3947032 forward tRNA-Trp(CCA) [AS-TAS|W|Traceable author statement] 7033244, Weak b3761 ECK120001412 hdfR b4480 3947128 3947967 reverse DNA-binding transcriptional dual regulator HdfR [EXP-IDA-PART-PURIFIED-PROTEIN-NH|W|Assay of protein partially-purified from its native host],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 10913108,21034467,28484043, Weak b3762,b3763,b4480 ECK120001413 maoP b3764 3948086 3948424 forward macrodomain Ori protein [EXP-IMP|W|Inferred from mutant phenotype] 27627105,34910273, Weak b3764 ECK120001235 yifB b3765 3948449 3949969 reverse putative magnesium chelatase YifB [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 15037234, Weak b3765 ECK120001244 ilvL b3766 3950322 3950420 forward operon leader peptide [EXP-IDA|W|Inferred from direct assay] 6154938, Weak b3766 ECK120048853 ilvX b4669 3950507 3950557 forward uncharacterized protein IlvX b4669 ECK120004461 ilvG b4488 3950560 3952204 forward acetolactate synthase II subunit IlvG b3767,b3768,b4488 ECK120000494 ilvM b3769 3952201 3952464 forward acetolactate synthase II subunit IlvM b3769 ECK120000490 ilvE b3770 3952484 3953413 forward branched-chain-amino-acid aminotransferase 3897211, b3770 ECK120000489 ilvD b3771 3953478 3955328 forward dihydroxy-acid dehydratase b3771 ECK120000486 ilvA b3772 3955331 3956875 forward threonine deaminase b3772 ECK120000496 ilvY b3773 3956927 3957820 reverse DNA-binding transcriptional dual regulator IlvY 113381,1379743,3003115,3062177, b3773 ECK120000488 ilvC b3774 3957970 3959445 forward ketol-acid reductoisomerase (NADP) b3774 ECK120002222 ppiC b3775 3959532 3959813 reverse peptidyl-prolyl isomerase C b3775 ECK120004310 yifN b3777 3960012 3960460 reverse putative toxin YifN b3777 ECK120000828 rep b3778 3960677 3962698 forward ATP-dependent DNA helicase Rep b3778 ECK120000406 gpp b3779 3962745 3964229 reverse guanosine-5'-triphosphate,3'-diphosphate phosphatase 372753, b3779 ECK120000835 rhlB b3780 3964365 3965630 reverse ATP-dependent RNA helicase RhlB b3780 ECK120001020 trxA b3781 3965761 3966090 forward thioredoxin 1 [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 21570393,2187529,3891733, Strong b3781 ECK120002284 rhoL b3782 3966231 3966332 forward operon leader peptide [EXP-IMP|W|Inferred from mutant phenotype] 2423505, Weak b3782 ECK120000836 rho b3783 3966417 3967676 forward transcription termination factor Rho b3783 ECK120000831 rfe b3784 3967916 3969019 forward UDP--acetylglucosaminephosphotransferase b3784 ECK120001268 wzzE b3785 3969031 3970077 forward enterobacterial common antigen polysaccharide co-polymerase [EXP-IMP|W|Inferred from mutant phenotype] 10515954,25307743, Weak b3785 ECK120001414 wecB b3786 3970133 3971263 forward UDP--acetylglucosamine 2-epimerase 10930727,11846551,11929520,16021622,1730666, b3786 ECK120001415 wecC b3787 3971260 3972522 forward UDP--acetyl-D-mannosamine dehydrogenase b3787 ECK120001416 rffG b3788 3972522 3973589 forward dTDP-glucose 4,6-dehydratase 2 b3788 ECK120001417 rffH b3789 3973608 3974489 forward glucose-1-phosphate thymidylyltransferase 2 b3789 ECK120001418 rffC b3790 3974467 3975141 forward b3790 ECK120001419 wecE b3791 3975146 3976276 forward dTDP-4-dehydro-6-deoxy-D-glucose transaminase 22492444, b3791 ECK120001442 wzxE b3792 3976278 3977528 forward lipid III flippase 16855227,27226142,9274022, b3792 ECK120004311 wecF b4481 3977525 3978604 forward TDP--acetylfucosaminyltransferase 1722555,1730666,60330, b4404,b4405,b4481 ECK120001420 wzyE b3793 3978601 3979953 forward enterobacterial common antigen polymerase 12618464,34070637, b3793 ECK120001421 rffM b3794 3979956 3980696 forward UDP-N-acetyl-D-mannosaminuronic acid transferase 12618464, b3794 ECK120001422 yifK b3795 3980887 3982272 forward putative transporter YifK [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10931886,24391513,31438868, Weak b3795 ECK120002460 argX b3796 3982375 3982451 forward tRNA-Arg(CCG) [AS-TAS|W|Traceable author statement] 7033244, Weak b3796 ECK120002484 hisR b3797 3982509 3982585 forward tRNA-His(GUG) [AS-TAS|W|Traceable author statement] 7033244, Weak b3797 ECK120002491 leuT b3798 3982606 3982692 forward tRNA-Leu(CAG) [AS-TAS|W|Traceable author statement] 7033244, Weak b3798 ECK120002510 proM b3799 3982735 3982811 forward tRNA-Pro(UGG) [AS-TAS|W|Traceable author statement] 26140378,27288443,7033244, Weak b3799 ECK120000086 aslB b3800 3982958 3984193 forward putative anaerobic sulfatase maturation enzyme AslB [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 16766528, Weak b3800 ECK120000085 aslA b3801 3984352 3986007 reverse putative sulfatase AslA 415041,8432711, b3801 ECK120002585 glmZ b4456 3986432 3986603 forward small regulatory RNA GlmZ [EXP-IMP|W|Inferred from mutant phenotype] 11448770,17824929,22661574,28119418,28977623,30287822,32424019, Weak b4456 ECK120000427 hemY b3802 3986686 3987882 reverse protein HemY 3294419, b3802 ECK120000426 hemX b3803 3987885 3989066 reverse PF04375 family protein HemX b3803 ECK120000423 hemD b3804 3989088 3989828 reverse uroporphyrinogen-III synthase 34070637, b3804 ECK120000422 hemC b3805 3989825 3990766 reverse hydroxymethylbilane synthase b3805 ECK120000166 cyaA b3806 3991153 3993699 forward adenylate cyclase 4583241, b3806 ECK120001597 cyaY b3807 3993739 3994059 reverse frataxin CyaY [EXP|W|Inferred from experiment],[EXP-IMP|W|Inferred from mutant phenotype] 12140189,25430730,25772583,27474202, Weak b3807 ECK120004312 yzcX b3808 3993850 3994335 forward protein YzcX b3808 ECK120016323 yifL b4558 3994522 3994725 forward putative lipoprotein YifL 24391520,32053772, b4558 ECK120000203 dapF b3809 3994762 3995586 forward diaminopimelate epimerase b3809 ECK120001181 yigA b3810 3995583 3996290 forward DUF484 domain-containing protein YigA b3810 ECK120001058 xerC b3811 3996287 3997183 forward site-specific tyrosine recombinase [EXP-IMP|W|Inferred from mutant phenotype] 1931824, Weak b3811 ECK120001182 yigB b3812 3997183 3997899 forward 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase b3812 ECK120001053 uvrD b3813 3997983 4000145 forward DNA helicase II b3813 ECK120001424 yigE b4482 4000292 4001056 reverse DUF2233 domain-containing protein YigE b3814,b3815,b4482 ECK125135307 Phantom Gene 4001191 4001334 forward ECK125286414 ysgD b4799 4001218 4001274 forward protein YsgD b4799 ECK120001425 corA b3816 4001426 4002376 forward Ni transporter b3816 ECK120001426 yigF b3817 4002419 4002799 reverse DUF2628 domain-containing protein YigF b3817 ECK120001427 yigG b3818 4002813 4003193 reverse inner membrane protein b3818 ECK120001428 rarD b3819 4003288 4004178 reverse putative transporter RarD b3819 ECK120001429 yigI b3820 4004230 4004697 reverse putative thioesterase YigI b3820 ECK120000729 pldA b3821 4004862 4005731 forward outer membrane phospholipase A 6304472, b3821 ECK120000824 recQ b3822 4005864 4007693 forward ATP-dependent DNA helicase RecQ 25411316,3027506,34526657, b3822 ECK120001430 rhtC b3823 4007757 4008377 forward L-threonine exporter 15981566,17025177,26363557,28911185, b3823 ECK120001431 rhtB b3824 4008439 4009059 reverse L-homoserine/L-homoserine lactone/L-threonine exporter 28911185, b3824 ECK120000730 pldB b3825 4009170 4010192 forward lysophospholipase L2 1646933,1649829,2934380,4350652, b3825 ECK120001432 yigL b3826 4010200 4011000 forward phosphosugar phosphatase YigL 15942870,26411266, b3826 ECK120001433 bioP b3827 4011076 4011975 forward biotin transporter 1091631,17301237,23836870,338581,3890946,4551983,4565539,4598072,4894285,6991489,7046803, b3827 ECK120000584 metR b3828 4011863 4012816 reverse DNA-binding transcriptional dual regulator MetR 1379743,2205852,2643109, b3828 ECK120000577 metE b3829 4013053 4015314 forward cobalamin-independent homocysteine transmethylase b3829 ECK120004313 ysgA b3830 4015354 4016169 reverse putative dienelactone hydrolase b3830 ECK120001034 udp b3831 4016431 4017192 forward uridine phosphorylase 10424909,11443940,11812223,12997187,14499937,15027196,171553,1747419,18482579,186698,2172808,2205199,2411635,2449419,2515986,2668121,2674901,2954322,2985468,3100391,3122186,3128435,3294419,3318842,3535805,370101,3894163,3907995,4930081,6352408,6356978,6360949,6805517,7002724,7030867,7049834,7049835,7512551,769833,776741,7888995,7920254,8142484,8555362,8626289,8647421,8648611,8670308,8714134,9090462,9113736,9161714,9225258,9541810,9546202,9661793, b3831 ECK120001434 rmuC b3832 4017333 4018760 forward putative recombination limiting protein RmuC [EXP-IGI|W|Inferred from genetic interaction] 10886369, Weak b3832 ECK120001435 ubiE b3833 4018855 4019610 forward bifunctional 2-octaprenyl-6-methoxy-1,4-benzoquinol methylase and demethylmenaquinone methyltransferase 16140031,17968530,195601,21445887,27656164,9325429, b3833 ECK120001436 ubiJ b3834 4019624 4020229 forward ubiquinone biosynthesis accessory factor UbiJ [EXP-IMP|W|Inferred from mutant phenotype] 22803341,24142253,28900423,28915357,34117231, Weak b3834 ECK125145757 esrE b4707 4019978 4020229 forward small RNA EsrE b4707 ECK120001437 ubiB b3835 4020226 4021866 forward ubiquinone biosynthesis protein UbiB [EXP-IMP|W|Inferred from mutant phenotype] 22952665,365223,9422602, Weak b3835 ECK120004314 tatA b3836 4021945 4022214 forward twin arginine protein translocation system - TatA protein 17669355,21683683, b3836 ECK120004315 tatB b3838 4022218 4022733 forward twin arginine protein translocation system - TatB protein 11922668,16973610,31438868, b3838 ECK120001438 tatC b3839 4022736 4023512 forward twin arginine protein translocation system - TatC protein 11279240,11781311,11922668,16855227,17545291,22742417, b3839 ECK120001439 tatD b4483 4023554 4024336 forward 3' → 5' ssDNA/RNA exonuclease TatD b3840,b3841,b4483 ECK120000830 rfaH b3842 4024333 4024821 reverse transcription antiterminator RfaH [EXP-IDA|W|Inferred from direct assay] 12007406,21777806,2437101,31616400,6192244,8001774,8820641, Weak b3842 ECK120001363 ubiD b3843 4024988 4026481 forward 3-octaprenyl-4-hydroxybenzoate decarboxylase b3843 ECK120000328 fre b3844 4026527 4027228 forward NAD(P)H-flavin reductase 10742223,1601132,19139094,31281172,4154078,7042345,8132544, b3844 ECK120000272 fadA b3845 4027609 4028772 reverse 3-ketoacyl-CoA thiolase 12351234,1678742,1699931,2191949,22038610,2204034,25645093,29807110,3312186,334745,4887396,6402028,7024730, b3845 ECK120000273 fadB b3846 4028782 4030971 reverse multifunctional enoyl-CoA hydratase, 3-hydroxyacyl-CoA epimerase, Δ-enoyl-CoA isomerase, L-3-hydroxyacyl-CoA dehydrogenase 1341905,1438362,1699931,1712230,2191949,2204034,28754100,29807110,3286611,3312186,3528151,3536901,4928881,7024731, b3846 ECK120000690 pepQ b3847 4031161 4032492 forward Xaa-Pro dipeptidase b3847 ECK120001440 yigZ b3848 4032492 4033106 forward IMPACT family member YigZ b3848 ECK120001010 trkH b3849 4033145 4034596 forward K transporter TrkH 11092250,15205426,20333436,31438868,9798786, b3849 ECK120001441 hemG b3850 4034608 4035153 forward protoporphyrinogen oxidase b3850 ECK120002526 rrsA b3851 4035531 4037072 forward 16S ribosomal RNA b3851 ECK120002485 ileT b3852 4037141 4037217 forward tRNA-Ile(GAU) [AS-TAS|W|Traceable author statement] 7033244, Weak b3852 ECK120002451 alaT b3853 4037260 4037335 forward tRNA-Ala(UGC) [AS-TAS|W|Traceable author statement] 7033244, Weak b3853 ECK120002519 rrlA b3854 4037519 4040423 forward 23S ribosomal RNA 16950778, b3854 ECK120002512 rrfA b3855 4040517 4040636 forward 5S ribosomal RNA 6181508, b3855 ECK120001760 mobB b3856 4040906 4041433 reverse molybdopterin-guanine dinucleotide biosynthesis adaptor protein b3856 ECK120001761 mobA b3857 4041415 4041999 reverse molybdenum cofactor guanylyltransferase 1459941,2141097,3035339,3301812,3308848,3524687,3525161,3881754,4552503,4576401,4912199,4941570,6307982,6370312,6991254,7031034,772165,7721698,9516445, b3857 ECK120001762 yihD b3858 4042069 4042338 forward DUF1040 domain-containing protein YihD 9868784, b3858 ECK120001763 srkA b3859 4042415 4043401 forward stress response kinase A b3859 ECK120001270 dsbA b3860 4043418 4044044 forward thiol:disulfide oxidoreductase DsbA 10210189,10369668,10828992,10841975,11208797,12072444,12498799,14747707,15755450,16586531,17702751,19968787,20052969,26209678,7693702,7890650,8110795,8155639,8218303,8411164,8617214,8995246,9099671,9572841, b3860 ECK120001764 yihF b3861 4044199 4045629 forward DUF945 domain-containing protein YihF b3861 ECK120001765 yihG b3862 4045670 4046602 reverse 1-acylglycerol-3-phosphate -acyltransferase YihG b3862 ECK120000737 polA b3863 4046966 4049752 forward DNA polymerase I 15095980,33573045, b3863 ECK120002540 spf b3864 4049899 4050009 forward small regulatory RNA Spot 42 [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IPI|W|Inferred from physical interaction] 12069726,12101127,1715853,18388495,23980183,26045496,30287822,6183253, Weak b3864 ECK120001183 yihA b3865 4050133 4050765 reverse GTP-binding protein YihA [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 10572302,12670677, Weak b3865 ECK120002586 csrC b4457 4051036 4051281 forward small regulatory RNA CsrC [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 12694612,15916613,17064377,19619561,24708042,28732463,30589862, Weak b4457 ECK120001766 yihI b3866 4051347 4051856 forward Der GTPase-activating protein YihI b3866 ECK120001767 hemN b3867 4052045 4053418 forward coproporphyrinogen III dehydrogenase b3867 ECK120048869 yshB b4686 4053647 4053757 reverse uncharacterized protein YshB b4686 ECK120000378 glnG b3868 4053869 4055278 reverse DNA-binding transcriptional dual regulator NtrC 10960104,41243, b3868 ECK120000380 glnL b3869 4055290 4056339 reverse protein histidine kinase NtrB b3869 ECK120000376 glnA b3870 4056625 4058034 reverse glutamine synthetase b3870 ECK125135309 Phantom Gene 4058171 4058242 forward ECK120001768 bipA b3871 4058407 4060230 forward 50S ribosomal subunit assembly factor BipA [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 12654836,18820021,20477873,25777676,29511080, Weak b3871 ECK120001769 yihL b3872 4060447 4061157 forward putative DNA-binding transcriptional regulator YihL [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,12582243,15556475, Weak b3872 ECK120001770 yihM b3873 4061165 4062145 forward putative TIM barrel domain-containing protein YihM b3873 ECK120001771 yihN b3874 4062247 4063512 forward putative transporter YihN 24391520,31438868,33406033, b3874 ECK120004316 ompL b3875 4063603 4064295 reverse putative outer membrane porin L [EXP|W|Inferred from experiment] Weak b3875 ECK120001772 yihO b3876 4064363 4065766 reverse putative sulfoquinovose transporter 31438868, b3876 ECK120001773 yihP b3877 4065809 4067194 reverse putative 2,3-dihydroxypropane-1-sulfonate export protein 24463506,31438868, b3877 ECK120001774 yihQ b3878 4067240 4069276 reverse sulfoquinovosidase b3878 ECK120001775 yihR b3879 4069475 4070401 reverse putative sulfoquinovose mutarotase YihR [COMP-HINF-IGC|W|Inferred from genomic context],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 16385049,29535276, Weak b3879 ECK120001776 yihS b3880 4070515 4071756 reverse sulfoquinovose isomerase 29453395, b3880 ECK120001777 yihT b3881 4071773 4072651 reverse 6-deoxy-6-sulfofructose-1-phosphate aldolase b3881 ECK120001778 yihU b3882 4072675 4073571 reverse 3-sulfolactaldehyde reductase b3882 ECK120001779 yihV b3883 4073739 4074635 forward 6-deoxy-6-sulfofructose kinase b3883 ECK120001780 csqR b3884 4074669 4075454 forward DNA-binding transcriptional dual regulator CsqR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 10734204,15556475,29453395,30372406, Strong b3884 ECK120001781 yihX b3885 4075553 4076152 forward α-D-glucose-1-phosphate phosphatase YihX b3885 ECK120001782 yihY b3886 4076146 4077018 forward PF03631 family membrane protein YihY b3886 ECK120001783 dtd b3887 4077015 4077452 forward D-aminoacyl-tRNA deacylase 15292242,4292198, b3887 ECK120001784 fabY b3888 4077449 4078438 forward putative fatty acid biosynthesis enzyme FabY [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IGI|W|Inferred from genetic interaction] 31331975, Weak b3888 ECK120001785 yiiE b3889 4079291 4079509 forward putative DNA-binding transcriptional regulator YiiE b3889 ECK120001786 yiiF b3890 4079751 4079969 forward protein YiiF b3890 ECK120000278 fdhE b3891 4080299 4081228 reverse formate dehydrogenase formation protein b3891 ECK120001787 fdoI b3892 4081225 4081860 reverse formate dehydrogenase O subunit γ b3892 ECK120001788 fdoH b3893 4081857 4082759 reverse formate dehydrogenase O subunit β b3893 ECK120001789 fdoG b3894 4082772 4085822 reverse formate dehydrogenase O subunit α b3894 ECK120001790 fdhD b3895 4086016 4086849 forward sulfurtransferase for molybdenum cofactor sulfuration b3895 ECK120001791 yiiG b3896 4087002 4088057 forward DUF3829 domain-containing lipoprotein YiiG 32053772, b3896 ECK120001792 frvR b3897 4088107 4089855 reverse putative DNA-binding transcriptional regulator FrvR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 10734204,15556475,8019415, Weak b3897 ECK120001793 frvX b3898 4089855 4090925 reverse peptidase M42 family protein FrvX b3898 ECK120001794 frvB b3899 4090915 4092366 reverse putative PTS enzyme IIBC component FrvB 8346018,8396120, b3899 ECK120001795 frvA b3900 4092377 4092823 reverse putative PTS enzyme IIA component FrvA b3900 ECK120001796 rhaM b3901 4093124 4093438 reverse L-rhamnose mutarotase b3901 ECK120001797 rhaD b3902 4093448 4094272 reverse rhamnulose-1-phosphate aldolase 19115296,19579240, b3902 ECK120001798 rhaA b3903 4094723 4095982 reverse L-rhamnose isomerase 13412966,13416204,16233647,17572092,26875877,31145478,3301811,7961955,8346018,8396120, b3903 ECK120001799 rhaB b3904 4095979 4097448 reverse rhamnulokinase b3904 ECK120000834 rhaS b3905 4097736 4098572 forward DNA-binding transcriptional activator RhaS 3316663,8230210,8346018, b3905 ECK120000833 rhaR b3906 4098646 4099494 forward DNA-binding transcriptional activator RhaR 1339463,1551902,3316663,8230210,8346018, b3906 ECK120001284 rhaT b3907 4099491 4100525 reverse rhamnose/lyxose:H symporter b3907 ECK120000942 sodA b3908 4100810 4101430 forward superoxide dismutase (Mn) 1577750,21059273,22061896,22450378,2254340,23497217,23536297,24839442,24952731,25070093,25269891,25434626,25845584,2644272,26461113,26492340,26953142,28113116,3279033,3320044, b3908 ECK120001800 kdgT b3909 4101690 4102673 forward 2-dehydro-3-deoxy-D-gluconate:H symporter b3909 ECK120001801 yiiM b3910 4102822 4103496 forward 6-hydroxyaminopurine reductase b3910 ECK120000159 cpxA b3911 4103602 4104975 reverse sensor histidine kinase CpxA b3911 ECK120000017 cpxR b3912 4104972 4105670 reverse DNA-binding transcriptional dual regulator CpxR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[EXP-IPI|W|Inferred from physical interaction] 1482126,15686558,16077119,16487683,2157156,7699720,7883164,8098993,8294007,9159398, Weak b3912 ECK120004317 cpxP b4484 4105820 4106320 forward periplasmic protein CpxP 9473036, b3913,b4484 ECK125230238 cpxQ b4716 4106330 4106387 forward small regulatory RNA CpxQ [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 27048800, Weak b4716 ECK120001803 fieF b3915 4106469 4107371 forward Zn exporter 17885121, b3915 ECK120000691 pfkA b3916 4107552 4108514 forward 6-phosphofructokinase 1 b3916 ECK120000918 sbp b3917 4108834 4109823 forward sulfate/thiosulfate ABC transporter periplasmic binding protein Sbp b3917 ECK120000134 cdh b3918 4109930 4110685 forward CDP-diacylglycerol diphosphatase b3918 ECK120001004 tpiA b3919 4110740 4111507 reverse triose-phosphate isomerase b3919 ECK120001804 yiiQ b3920 4111615 4112214 reverse DUF1454 domain-containing protein YiiQ b3920 ECK120001805 yiiR b3921 4112315 4112755 forward DUF805 domain-containing protein YiiR b3921 ECK120001806 yiiS b3922 4112967 4113266 forward DUF406 domain-containing protein YiiS [COMP-HINF|W|Inferred by a human based on computational evidence] 11574054,24391520, Weak b3922 ECK120001807 uspD b3923 4113293 4113721 forward universal stress protein D b3923 ECK120000621 fpr b3924 4113726 4114472 reverse flavodoxin/ferredoxin-NADP reductase 11401718,11493691,11724537,15308657,16549675,17157494,17216460,24016774,24025246,26177696,31281172,7872787,7961651,8626315,9370367,9558349,9782486, b3924 ECK120001472 glpX b3925 4114569 4115579 reverse fructose-1,6-bisphosphatase 2 b3925 ECK120000391 glpK b3926 4115714 4117222 reverse glycerol kinase 11013401,11443083,11544231,11811537,12829458,1368620,14067091,14314355,15593263,16263707,16562137,19189409,19819219,19893610,2012608,2170343,226119,237175,2544860,26691989,2838275,2851011,325162,4563976,4934061,4941552,4945198,5321485,5327904,6243477,6319974,6368745,8170944, b3926 ECK120000389 glpF b3927 4117245 4118090 reverse glycerol facilitator 11015209,11320116,11445582,11743188,11927589,11997475,12080108,12206912,12824546,12829458,12829462,1400248,15048815,15451676,15601207,15850456,15859950,15951380,16084383,16399837,16581540,16851049,17056733,17713961,17828601,17921212,18284214,20000688,20573441,2170343,22035256,23506682,26287624,29069569,30791644,347028,3520231,4934061,7493926,8310182, b3927 ECK120001808 zapB b3928 4118515 4118760 forward cell division factor ZapB 22532809,28249098, b3928 ECK120001809 rraA b3929 4118845 4119330 reverse ribonuclease E inhibitor protein A 28645581, b3929 ECK120001810 menA b3930 4119423 4120349 reverse 1,4-dihydroxy-2-naphthoate octaprenyltransferase 195602,21445887, b3930 ECK120001811 hslU b3931 4120416 4121747 reverse ATPase component of the HslVU protease b3931 ECK120001619 hslV b3932 4121757 4122287 reverse peptidase component of the HslVU protease b3932 ECK120001483 ftsN b3933 4122380 4123339 reverse cell division protein FtsN [EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 11703663,15774864,16803586,17938168,18165305,19854895,20497333,22328664,25496160,27785850,30056491,32866331,8509333,9282742, Weak b3933 ECK120000194 cytR b3934 4123431 4124456 reverse DNA-binding transcriptional repressor CytR 2162050,2162467,3515317,8346018, b3934 ECK120000754 priA b3935 4124612 4126810 reverse primosomal protein N' [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 127175,12917421,1662369,2162049,2162050, Weak b3935 ECK120000880 rpmE b3936 4127013 4127225 forward 50S ribosomal subunit protein L31 29551268,32448158,32814033,7026537, b3936 ECK120001812 yiiX b3937 4127286 4127894 reverse putative lipid-binding hydrolase YiiX 21799766, b3937 ECK120000581 metJ b3938 4128078 4128395 reverse DNA-binding transcriptional repressor MetJ b3938 ECK120000575 metB b3939 4128672 4129832 forward -succinylhomoserine lyase b3939 ECK120000583 metL b3940 4129835 4132267 forward fused aspartate kinase/homoserine dehydrogenase 2 b3940 ECK120000578 metF b3941 4132616 4133506 forward 5,10-methylenetetrahydrofolate reductase b3941 ECK120000504 katG b3942 4133835 4136015 forward catalase/hydroperoxidase HPI 11257507,11440837,11479716,12589799,14659082,15878120,16183297,18178143,2192882,3038676,3045098,3049591,3298208,3543208,7023475,7775420,8779563,8990289, b3942 ECK120001831 yijE b3943 4136108 4137013 forward cystine exporter 17025177,31438868, b3943 ECK120001832 yijF b3944 4137040 4137657 reverse DUF1287 domain-containing protein YijF [COMP-HINF|W|Inferred by a human based on computational evidence] 12192075, Weak b3944 ECK120001833 gldA b3945 4137932 4139035 reverse L-1,2-propanediol dehydrogenase / glycerol dehydrogenase b3945 ECK120001834 fsaB b3946 4139046 4139708 reverse fructose-6-phosphate aldolase 2 b3946 ECK120001835 ptsA b3947 4139720 4142221 reverse putative PTS multiphosphoryl transfer protein PtsA [COMP-HINF|W|Inferred by a human based on computational evidence] 7773398, Weak b3947 ECK120001836 frwC b3949 4142530 4143609 forward putative PTS enzyme IIC component FrwC b3949 ECK120001837 frwB b3950 4143624 4143944 forward putative PTS enzyme IIB component FrwB 16606699, b3950 ECK120001838 pflD b3951 4143995 4146292 forward putative formate acetyltransferase 2 [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 7773398, Weak b3951 ECK120001839 pflC b3952 4146258 4147136 forward putative pyruvate formate-lyase 2 activating enzyme PflC [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 7773398, Weak b3952 ECK120001840 frwD b3953 4147138 4147479 forward putative PTS enzyme IIB component FrwD 18680461,27215198, b3953 ECK120001841 yijO b3954 4147466 4148317 reverse putative DNA-binding transcriptional regulator YijO [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475, Weak b3954 ECK120001842 eptC b3955 4148532 4150265 reverse phosphoethanolamine transferase EptC b3955 ECK120000747 ppc b3956 4150447 4153098 reverse phosphoenolpyruvate carboxylase 10745200,10753455,10788348,11056062,11741855,11946104,12790684,12966569,14285262,14511906,14661115,15448692,15458351,15806547,15954317,16319065,17028777,17715942,18045419,18391462,20334648,20440535,23128557,231541,23747698,23957584,24432661,25178795,25178796,25874556,25890056,31218797,3125163,31281927,32442368,3519602,361729,370110,383705,3902793,3936496,42643,4927673,6086598,6396163,6995455,7040354,765753,7772842,7832509,8106492,9951527, b3956 ECK120001259 argE b3957 4153696 4154847 reverse acetylornithine deacetylase b3957 ECK120000061 argC b3958 4155001 4156005 forward N-acetylglutamylphosphate reductase b3958 ECK120000060 argB b3959 4156013 4156789 forward acetylglutamate kinase b3959 ECK120001201 argH b3960 4156850 4158223 forward argininosuccinate lyase b3960 ECK120002558 oxyS b4458 4158278 4158394 reverse small regulatory RNA OxyS [EXP-IMP|W|Inferred from mutant phenotype] 16030151,16597239,18467773,19119855,21106118,21205841,23011127,24169950,25582129,25724987,25798870,25873159,26960359,27095210,28119418,30340824,7986015,9230301, Weak b4458 ECK120000674 oxyR b3961 4158490 4159407 forward DNA-binding transcriptional dual regulator OxyR [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 1864839,2167922,22539721,2471187,2511419,2551682,8265357,8483417, Strong b3961 ECK120001392 sthA b3962 4159390 4160790 reverse soluble pyridine nucleotide transhydrogenase 19522528,20299454,23737072, b3962 ECK120001361 fabR b3963 4161067 4161771 forward DNA-binding transcriptional repressor FabR [EXP-IDA|W|Inferred from direct assay],[EXP-IEP|W|Inferred from expression pattern],[EXP-IPI|W|Inferred from physical interaction] 11160901,11859088, Weak b3963 ECK120001362 yijD b3964 4161771 4162130 forward DUF1422 domain-containing inner membrane protein YijD 17456747, b3964 ECK120001011 trmA b3965 4162170 4163270 reverse tRNA mU54 methyltransferase 11717300,1447162,1821774,2999071,9204554, b3965 ECK120000122 btuB b3966 4163639 4165483 forward cobalamin outer membrane transporter 11347264,12558182,12804762,12902336,12958215,137230,14611209,14704351,15465872,16549429,16820681,16922495,17277071,17908684,18092811,18408035,1885541,18990718,19927326,20816073,21354401,23176499,25432761,2644187,2844761,28483920,30848905,3108627,31582182,32609716,33031737,33453274,34251336,34792069,4934062,6447139,7050093,7592472,8132153,8752353,9813013,9813031, b3966 ECK120001184 murI b3967 4165428 4166285 forward glutamate racemase 23929705,2832706,33221881,7629013,7746157,7904596,9501533, b3967 ECK120002527 rrsB b3968 4166659 4168200 forward 16S ribosomal RNA 10753935,10844684,10919826,1094419,1101264,1102922,1103124,110460,11751827,12087167,12498,12902289,12903214,14510386,1646122,1716101,1718749,1764510,1764516,2145040,2168847,2222527,2387410,2435709,2443830,2448485,2473375,2685545,2689447,2833391,3013618,3071662,3071664,319193,320561,326259,327272,327273,3277949,331075,331313,3313279,3329282,342117,344139,348233,365689,378405,383432,384145,3894326,390405,392468,407931,4560773,4564202,4918356,4942898,4943519,6285294,6330033,6361011,6752954,6995826,7516168,7601845,769922,7718670,782716,782717,789334,793615,8041615,8312257,8377198,8419334,8515441,9034358,9226253,9501232,9769102, b3968 ECK120002474 gltT b3969 4168372 4168447 forward tRNA-Glu(UUC) [AS-TAS|W|Traceable author statement] 7033244, Weak b3969 ECK120002520 rrlB b3970 4168641 4171544 forward 23S ribosomal RNA [EXP-TAS|W|Traceable author statement to experimental support] 10051579,10464195,10525403,10793686,10844684,1094419,10964562,10986461,1098691,1101264,1102922,1103090,1103124,11157269,11350034,11517305,11574482,11675490,11680845,11741781,11751827,11888286,11955006,11991636,12022228,12034826,12467398,12498,12533472,12888505,1719209,1918155,1981803,2197598,2407189,2473375,3013618,3048270,3053641,3060850,3089782,319193,319197,3226909,325525,327272,327273,3277949,329865,331075,331313,3313279,3329282,342117,355851,359042,388189,3894326,390405,407931,4563865,4584388,4918356,4931952,4942898,4943519,6158039,6162473,6170632,6173374,6193815,6255418,6349628,6361011,6750359,6996708,7016337,7041903,7514294,7529560,7567991,7601845,7682175,775291,782716,782717,785385,789334,791272,8031879,805122,8253085,8515441,8524828,8643399,8643630,8654409,8710862,8834779,8918803,9016593,9034358,9135982,9367788,9396814,9501232,9573162,9586034,9620960,9769102,9836593,9989214, Weak b3970 ECK120002513 rrfB b3971 4171637 4171756 forward 5S ribosomal RNA [EXP-TAS|W|Traceable author statement to experimental support] 11401702,11488615,164889,1709493,1709723,1718749,1764510,2190187,2412207,2493632,3013618,3089782,324975,327272,331075,3315008,342117,359042,4198187,4216514,4550693,4571522,4591367,4609878,4621557,4881049,4881332,4906324,4906608,4918254,4920877,4924729,4931952,4944480,4993318,6178431,6188537,6255417,6390428,6765232,7024913,782717,805122,810137,95791,9862991,9878392, Weak b3971 ECK120001185 murB b3972 4172057 4173085 forward UDP--acetylenolpyruvoylglucosamine reductase 11160101,14659546,24389752,29363274,29968120,30107969,31967349,31985370,32220665,32340255,32365907,32711085,33029832,33802949,34323658,34356726, b3972 ECK120000119 birA b3973 4173082 4174047 forward DNA-binding transcriptional repressor/biotin-[acetyl-CoA-carboxylase] ligase BirA [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IPI|W|Inferred from physical interaction] 1097077,11106165,30904393,3325774,350835,3536662,366433,3899863,6456358,7024555,7945216,9750231, Weak b3973 ECK120000913 coaA b3974 4174076 4175026 reverse pantothenate kinase 21551303,22691444,23550886,24333332, b3974 ECK120004318 Phantom Gene b3975 4175213 4175368 reverse b3975 ECK120002544 thrU b3976 4175388 4175463 forward tRNA-Thr(UGU) [AS-TAS|W|Traceable author statement] 6761541,7033244, Weak b3976 ECK120002549 tyrU b3977 4175472 4175556 forward tRNA-Tyr(GUA) [AS-TAS|W|Traceable author statement] 11946953,27551044,7033244, Weak b3977 ECK120002478 glyT b3978 4175673 4175747 forward tRNA-Gly(UCC) b3978 ECK120002543 thrT b3979 4175754 4175829 forward tRNA-Thr(GGU) [AS-TAS|W|Traceable author statement] 6761541,7033244, Weak b3979 ECK120001026 tufB b3980 4175944 4177128 forward translation elongation factor Tu 2 1573997, b3980 ECK120000928 secE b3981 4177358 4177741 forward Sec translocon subunit SecE 10413486,12138117,18296516,2111734,2201574,34070637,7889938,8083155,8146153,8526914,8702704,8827448, b3981 ECK120000660 nusG b3982 4177743 4178288 forward transcription termination/antitermination factor NusG [EXP-IMP|W|Inferred from mutant phenotype] 10383769,1547498,32820061,32820062, Weak b3982 ECK120000863 rplK b3983 4178447 4178875 forward 50S ribosomal subunit protein L11 16682558,20237646,21394717,25126896,4211382,4604976,4616944, b3983 ECK120000855 rplA b3984 4178879 4179583 forward 50S ribosomal subunit protein L1 26668356, b3984 ECK120000862 rplJ b3985 4179996 4180493 forward 50S ribosomal subunit protein L10 b3985 ECK120000864 rplL b3986 4180560 4180925 forward 50S ribosomal subunit protein L12 28968100,30076302,32569619, b3986 ECK120000885 rpoB b3987 4181245 4185273 forward RNA polymerase subunit β 33303586, b3987 ECK120000886 rpoC b3988 4185350 4189573 forward RNA polymerase subunit β' 33303586, b3988 ECK120001393 yjaZ b3989 4189786 4190325 forward protein YjaZ b3989 ECK120002647 sroH b4691 4190327 4190487 reverse small RNA SroH b4691 ECK120001539 thiH b3990 4190735 4191868 reverse 2-iminoacetate synthase 10082377,4562671, b3990 ECK120001538 thiG b3991 4191865 4192635 reverse 1-deoxy-D-xylulose 5-phosphate:thiol sulfurtransferase 17969213,19923213, b3991 ECK120002671 thiS b4407 4192637 4192837 reverse sulfur carrier protein ThiS [EXP-IDA|W|Inferred from direct assay] 10781607,14757766,14983069,23638106,25721662,31442507,9632726, Weak b4407 ECK120001537 thiF b3992 4192821 4193576 reverse sulfur carrier protein ThiS adenylyltransferase b3992 ECK120001536 thiE b3993 4193569 4194204 reverse thiamine phosphate synthase 20406421, b3993 ECK120001535 thiC b3994 4194204 4196099 reverse phosphomethylpyrimidine synthase b3994 ECK120001677 rsd b3995 4196332 4196808 reverse regulator of sigma D [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IGI|W|Inferred from genetic interaction] 10947847,12023304,21573101,29288053,29915072,9560209, Weak b3995 ECK120001645 nudC b3996 4196903 4197676 forward RNA decapping hydrolase b3996 ECK120001497 hemE b3997 4197716 4198780 forward uroporphyrinogen decarboxylase 387909,7849561, b3997 ECK120001843 nfi b3998 4198790 4199461 forward endonuclease V 12730170,16952947,19043748,26244280,31444105,32109061,8990280, b3998 ECK120001844 yjaG b3999 4199504 4200094 forward DUF416 domain-containing protein YjaG b3999 ECK120000459 hupA b4000 4200281 4200553 forward DNA-binding protein HU-α b4000 ECK120001845 yjaH b4001 4200566 4201261 forward DUF1481 domain-containing protein YjaH b4001 ECK120001846 zraP b4002 4201263 4201688 reverse signaling pathway modulator ZraP b4002 ECK120000007 zraS b4003 4201926 4203323 forward sensor histidine kinase ZraS 12366850, b4003 ECK120000475 zraR b4004 4203320 4204645 forward DNA-binding transcriptional activator ZraR [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 11243806,1482126,2157156,7699720,8098993, Strong b4004 ECK120000783 purD b4005 4204642 4205931 reverse phosphoribosylamine—glycine ligase 2045358,2192230,2687276, b4005 ECK120000786 purH b4006 4205943 4207532 reverse bifunctional AICAR transformylase/IMP cyclohydrolase 2045358, b4006 ECK120002530 rrsE b4007 4208147 4209688 forward 16S ribosomal RNA 10753935,10844684,10919826,1094419,1101264,1102922,1103124,110460,11751827,12087167,12498,12902289,12903214,14510386,1646122,1716101,1718749,1764510,1764516,2145040,2168847,2222527,2387410,2435709,2443830,2448485,2473375,2685545,2689447,2833391,3013618,3071662,3071664,319193,320561,326259,327272,327273,3277949,331075,331313,3313279,3329282,342117,344139,348233,365689,378405,383432,384145,3894326,390405,392468,407931,4560773,4564202,4918356,4942898,4943519,6285294,6330033,6361011,6752954,6995826,7516168,7601845,769922,7718670,782716,782717,789334,793615,8041615,8312257,8377198,8419334,8515441,9034358,9226253,9501232,9769102, b4007 ECK120002476 gltV b4008 4209774 4209849 forward tRNA-Glu(UUC) [AS-TAS|W|Traceable author statement] 7033244, Weak b4008 ECK120002523 rrlE b4009 4210043 4212946 forward 23S ribosomal RNA [EXP-TAS|W|Traceable author statement to experimental support] 10051579,10464195,10525403,10793686,10844684,1094419,10964562,10986461,1098691,1101264,1102922,1103090,1103124,11157269,11350034,11517305,11574482,11675490,11680845,11741781,11751827,11888286,11955006,11991636,12022228,12034826,12467398,12498,12533472,12888505,1719209,1918155,1981803,2197598,2407189,2473375,3013618,3048270,3053641,3060850,3089782,319193,319197,3226909,325525,327272,327273,3277949,329865,331075,331313,3313279,3329282,342117,355851,359042,388189,3894326,390405,407931,4563865,4584388,4918356,4931952,4942898,4943519,6158039,6162473,6170632,6173374,6193815,6255418,6349628,6361011,6750359,6996708,7016337,7041903,7514294,7529560,7567991,7601845,7682175,775291,782716,782717,785385,789334,791272,8031879,805122,8253085,8515441,8524828,8643399,8643630,8654409,8710862,8834779,8918803,9016593,9034358,9135982,9367788,9396814,9501232,9573162,9586034,9620960,9769102,9836593,9989214, Weak b4009 ECK120002516 rrfE b4010 4213040 4213159 forward 5S ribosomal RNA [EXP-TAS|W|Traceable author statement to experimental support] 11401702,11488615,164889,1709493,1709723,1718749,1764510,2190187,2412207,2493632,3013618,3089782,324975,327272,331075,3315008,342117,359042,4198187,4216514,4550693,4571522,4591367,4609878,4621557,4881049,4881332,4906324,4906608,4918254,4920877,4924729,4931952,4944480,4993318,6178431,6188537,6255417,6390428,6765232,7024913,782717,805122,810137,95791,9862991,9878392, Weak b4010 ECK120001186 yjaA b4011 4213234 4213617 forward stress response protein [EXP-IMP|W|Inferred from mutant phenotype] 19919618, Weak b4011 ECK120001187 yjaB b4012 4213680 4214123 reverse peptidyl-lysine -acetyltransferase YjaB 9311119, b4012 ECK120000574 metA b4013 4214280 4215209 forward homoserine -succinyltransferase b4013 ECK120000020 aceB b4014 4215478 4217079 forward malate synthase A 3050899,3060852, b4014 ECK120000019 aceA b4015 4217109 4218413 forward isocitrate lyase 3049537,3290857, b4015 ECK120000023 aceK b4016 4218596 4220332 forward isocitrate dehydrogenase kinase/phosphatase 17617487,20198860,20223989,20665018,21870819,21881893,23718679,26079398,28916461,29392388,29424136,29432647,29477857,30615909,33539894, b4016 ECK125303715 aceK-int b4830 4218879 4218963 forward small RNA AceK-int b4830 ECK120001188 arpA b4017 4220301 4222487 reverse regulator of acetyl CoA synthetase b4017 ECK120000484 iclR b4018 4222804 4223628 reverse DNA-binding transcriptional repressor IclR [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IPI|W|Inferred from physical interaction] 12492863,1447784,1995429,1995431,2001680,2185227,8265357,8550439, Strong b4018 ECK120000580 metH b4019 4223828 4227511 forward cobalamin-dependent methionine synthase 13051887,2025237,21539330,2185137,23764826,26223547,5337044,8501076, b4019 ECK120001847 yjbB b4020 4227731 4229362 forward putative inorganic phosphate export protein YjbB 31438868, b4020 ECK120001848 pepE b4021 4229453 4230142 reverse peptidase E b4021 ECK120001849 rluF b4022 4230354 4231226 forward 23S rRNA pseudouridine synthase 27551044,8871555, b4022 ECK120001850 yjbD b4023 4231359 4231631 reverse DUF3811 domain-containing protein YjbD b4023 ECK120000543 lysC b4024 4231884 4233233 reverse aspartate kinase III b4024 ECK120000694 pgi b4025 4233758 4235407 forward glucose-6-phosphate isomerase b4025 ECK120001851 yjbE b4026 4235906 4236148 forward uncharacterized protein YjbE [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 16385049,17379715,24391520,34683400, Weak b4026 ECK120001852 yjbF b4027 4236262 4236900 forward lipoprotein YjbF [EXP-IMP|W|Inferred from mutant phenotype] 17379715,32053772,34683400, Weak b4027 ECK120001853 yjbG b4028 4236897 4237634 forward capsule biosynthesis GfcC family protein YjbG [EXP-IMP|W|Inferred from mutant phenotype] 17379715,34683400, Weak b4028 ECK120001854 yjbH b4029 4237634 4239730 forward putative lipoprotein YjbH [COMP-HINF|W|Inferred by a human based on computational evidence],[EXP-IMP|W|Inferred from mutant phenotype] 12192075,17379715,32053772,34683400, Weak b4029 ECK120030089 yjbT b4620 4239777 4240055 reverse PF17089 family protein YjbT b4620 ECK120001189 psiE b4030 4240325 4240735 forward putative phosphate starvation-inducible protein PsiE 11574054,17456747,2160940, b4030 ECK120001065 xylE b4031 4240779 4242254 reverse D-xylose:H symporter 32499529,3543693, b4031 ECK125302577 malH b4807 4242531 4242633 reverse small regulatory RNA MalH [EXP-IMP|W|Inferred from mutant phenotype] 32356726,33043783, Weak b4807 ECK120000549 malG b4032 4242626 4243516 reverse maltose ABC transporter membrane subunit MalG 8419303,9573205, b4032 ECK120000548 malF b4033 4243531 4245075 reverse maltose ABC transporter membrane subunit MalF 11114938,1885584,1915262,2170984,3294421,3317413,8636026, b4033 ECK120000547 malE b4034 4245229 4246419 reverse maltose ABC transporter periplasmic binding protein 1406246,15097997,15117946,16288781,16511487,17060917,17960247,18385983,19630440,21533070,22529943,22933379,24124463,24191053,29295923,3049536,3050132,33957147,3524683,3894331,393831,8399200,8411172,8663400,9106209,9211908,9211909,9211910,9765817, b4034 ECK120000551 malK b4035 4246784 4247899 forward maltose ABC transporter ATP binding subunit 10037713,11150310,15733913,19274733,26666844,29767997,6296778,7665528, b4035 ECK120000521 lamB b4036 4247971 4249311 forward maltose outer membrane channel / phage lambda receptor protein 29518576, b4036 ECK120000552 malM b4037 4249554 4250474 forward maltose regulon periplasmic protein b4037 ECK120001855 yjbI b4038 4250703 4252283 forward pentapeptide repeats-containing protein YjbI b4038 ECK120001337 ubiC b4039 4252506 4253003 forward chorismate lyase 11745165,1512213,1644758,25681964,31767748,8366060, b4039 ECK120001338 ubiA b4040 4253016 4253888 forward 4-hydroxybenzoate octaprenyltransferase b4040 ECK120000731 plsB b4041 4254043 4256466 reverse glycerol-3-phosphate 1--acyltransferase 6309817, b4041 ECK120000218 dgkA b4042 4256637 4257005 forward diacylglycerol kinase b4042 ECK120000526 lexA b4043 4257115 4257723 forward DNA-binding transcriptional repressor LexA 2780544,6261224,6272195,7013987,7027255,7027256,8076591,8265357, b4043 ECK120001447 dinF b4044 4257742 4259121 forward DNA damage-inducible protein F b4044 ECK120001856 yjbJ b4045 4259237 4259446 forward putative stress response protein YjbJ 29280215, b4045 ECK120001857 zur b4046 4259488 4260003 reverse DNA-binding transcriptional repressor Zur 11523983,11831459,11931550,12904577, b4046 ECK120001858 yjbL b4047 4260321 4260575 forward uncharacterized protein YjbL b4047 ECK120001859 yjbM b4048 4260599 4261306 forward DUF2713 domain-containing protein YjbM b4048 ECK120001860 dusA b4049 4261669 4262706 forward tRNA-dihydrouridine synthase A b4049 ECK120001861 pspG b4050 4262840 4263082 forward phage shock protein G b4050 ECK125256957 pspH b4758 4263139 4263249 forward small regulatory RNA PspH [EXP-IMP|W|Inferred from mutant phenotype] 25266388,27588604, Weak b4758 ECK120001448 qorA b4051 4263248 4264231 reverse putative quinone oxidoreductase 1 24482123, b4051 ECK120000230 dnaB b4052 4264314 4265729 forward replicative DNA helicase b4052 ECK120000001 alr b4053 4265782 4266861 forward alanine racemase 1 b4053 ECK120001029 tyrB b4054 4267114 4268307 forward tyrosine aminotransferase 323238,3521591,3907634, b4054 ECK120030090 yjbS b4621 4268809 4269012 reverse uncharacterized protein YjbS b4621 ECK120001862 aphA b4055 4269414 4270127 forward acid phosphatase / phosphotransferase b4055 ECK120001863 yjbQ b4056 4270238 4270654 forward PF01894 family protein YjbQ b4056 ECK120001864 yjbR b4057 4270658 4271014 forward PF04237 family protein YjbR b4057 ECK120001050 uvrA b4058 4271049 4273871 reverse UvrABC excision nuclease subunit A 30617079,33382157, b4058 ECK120000965 ssb b4059 4274125 4274661 forward ssDNA-binding protein b4059 ECK120001865 yjcB b4060 4274760 4275041 reverse uncharacterized protein YjcB b4060 ECK120001866 pdeC b4061 4275471 4277057 forward c-di-GMP phosphodiesterase PdeC 29018125, b4061 ECK120000947 soxS b4062 4277060 4277383 reverse DNA-binding transcriptional dual regulator SoxS [EXP|W|Inferred from experiment] 1653416,1708380,7891555,7896696,8034583,8226698,8265357, Weak b4062 ECK120000946 soxR b4063 4277469 4277933 forward DNA-binding transcriptional dual regulator SoxR [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host] 11470373,1400156,1653416,1708380,7673113, Strong b4063 ECK120002587 ryjA b4459 4277926 4278066 reverse small RNA RyjA 11448770, b4459 ECK120001867 ghxP b4064 4278479 4279828 forward guanine/hypoxanthine transporter GhxP b4064 ECK120001868 yjcE b4065 4279980 4281629 forward putative transporter YjcE 31438868, b4065 ECK120001869 yjcF b4066 4281783 4283075 reverse pentapeptide repeat-containing protein YjcF b4066 ECK120001870 actP b4067 4283253 4284902 reverse acetate/glycolate:cation symporter 14563880, b4067 ECK120001871 yjcH b4068 4284899 4285213 reverse DUF485 domain-containing inner membrane protein YjcH b4068 ECK120001411 acs b4069 4285413 4287371 reverse acetyl-CoA synthetase (AMP-forming) 14595781,16496143,17273855,18175070,19852855,19861135,19884769,20707605,20707865,22059728,22513097,24238347,24633370,24917678,25518064,25524697,27804304, b4069 ECK125303704 ytcB b4821 4287611 4287667 forward protein YtcB 34662240, b4821 ECK120001715 nrfA b4070 4287764 4289200 forward cytochrome nitrite reductase 11004182,18245085,18311941,18433623,22092912,334173,378660,8057835,9325429, b4070 ECK120001872 nrfB b4071 4289245 4289811 forward periplasmic nitrite reductase penta-heme -type cytochrome b4071 ECK120001873 nrfC b4072 4289808 4290479 forward putative menaquinol-cytochrome reductase 4Fe-4S subunit b4072 ECK120001874 nrfD b4073 4290476 4291432 forward putative menaquinol-cytochrome reductase subunit NrfD b4073 ECK120001875 nrfE b4074 4291512 4293170 forward putative cytochrome c-type biogenesis protein NrfE [EXP-IMP|W|Inferred from mutant phenotype] 9593308, Weak b4074 ECK120001876 nrfF b4075 4293163 4293546 forward putative formate-dependent nitrite reductase complex subunit NrfF [EXP-IMP|W|Inferred from mutant phenotype] 9593308, Weak b4075 ECK120001877 nrfG b4076 4293543 4294139 forward putative formate-dependent nitrite reductase complex subunit NrfG [EXP-IMP|W|Inferred from mutant phenotype] 9593308, Weak b4076 ECK120000398 gltP b4077 4294481 4295794 forward glutamate/aspartate : H symporter GltP 1551855,1971622, b4077 ECK120001878 yjcO b4078 4296436 4297125 reverse Sel1 repeat-containing protein YjcO b4078 ECK120000279 fdhF b4079 4297219 4299366 reverse formate dehydrogenase H 22194618, b4079 ECK120001879 mdtP b4080 4299564 4301030 reverse putative multidrug efflux pump outer membrane channel 32053772, b4080 ECK120001880 mdtO b4081 4301027 4303078 reverse putative multidrug efflux pump subunit MdtO 31438868, b4081 ECK120001881 mdtN b4082 4303078 4304109 reverse putative multidrug efflux pump membrane fusion protein 22344666,31438868, b4082 ECK120030091 ytcA b4622 4304128 4304403 reverse putative lipoprotein YtcA 32053772, b4622 ECK120001882 yjcS b4083 4304612 4306597 reverse linear primary-alkylsulfatase 25066955, b4083 ECK120001883 alsK b4084 4306870 4307799 reverse D-allose kinase b4084 ECK120001884 alsE b4085 4307783 4308478 reverse D-allulose-6-phosphate 3-epimerase b4085 ECK120001885 alsC b4086 4308489 4309469 reverse D-allose ABC transporter membrane subunit b4086 ECK120001886 alsA b4087 4309448 4310980 reverse D-allose ABC transporter ATP binding subunit b4087 ECK120002305 alsB b4088 4311107 4312042 reverse D-allose ABC transporter periplasmic binding protein 20711759, b4088 ECK120004319 alsR b4089 4312101 4312991 reverse DNA-binding transcriptional repressor AlsR [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 8576032,9401019, Weak b4089 ECK120001759 rpiB b4090 4313350 4313799 forward allose-6-phosphate isomerase / ribose-5-phosphate isomerase B 10559180, b4090 ECK120002649 yjdP b4487 4313868 4314197 forward protein YjdP b4487 ECK120000717 phnP b4092 4314344 4315102 reverse 5-phospho-α-D-ribosyl 1,2-cyclic phosphate phosphodiesterase b4092 ECK120000716 phnO b4093 4315104 4315538 reverse aminoalkylphosphonate -acetyltransferase b4093 ECK120000715 phnN b4094 4315525 4316082 reverse ribose 1,5-bisphosphate phosphokinase 21341651, b4094 ECK120000714 phnM b4095 4316082 4317218 reverse RPnTP hydrolase [EXP-IMP|W|Inferred from mutant phenotype] 8388873, Weak b4095 ECK120000713 phnL b4096 4317215 4317895 reverse methylphosphonate degradation complex subunit PhnL [EXP-IMP|W|Inferred from mutant phenotype] 8388873, Weak b4096 ECK120000712 phnK b4097 4318006 4318764 reverse carbon-phosphorus lyase subunit PhnK [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 1846145,8388873,9650256, Weak b4097 ECK120000711 phnJ b4098 4318761 4319606 reverse carbon-phosphorus lyase core complex subunit PhnJ b4098 ECK120000710 phnI b4099 4319599 4320663 reverse carbon-phosphorus lyase core complex subunit PhnI [EXP-IMP|W|Inferred from mutant phenotype] 8388873, Weak b4099 ECK120000709 phnH b4100 4320663 4321247 reverse carbon-phosphorus lyase core complex subunit PhnH b4100 ECK120000708 phnG b4101 4321244 4321696 reverse carbon-phosphorus lyase core complex subunit PhnG b4101 ECK120000707 phnF b4102 4321697 4322422 reverse putative transcriptional regulator PhnF [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 11756427,12757941,16672238, Weak b4102 ECK120001256 phnE b4583 4322443 4323281 reverse phosphonate/phosphate ABC transporter membrane subunit b4103,b4104,b4583 ECK120000706 phnD b4105 4323336 4324352 reverse phosphonate/phosphate ABC transporter periplasmic binding protein 22019591, b4105 ECK120000705 phnC b4106 4324377 4325165 reverse phosphonate/phosphate ABC transporter ATP binding subunit b4106 ECK120000704 yjdN b4107 4325298 4325741 reverse PF06983 family protein YjdN b4107 ECK125256963 naRNA6 4325805 4325881 reverse naRNA6 26307168, ECK125256972 naRNA5 4325905 4325981 reverse naRNA5 26307168, ECK125256968 naRNA4 4326005 4326081 reverse naRNA4 [EXP-IMP|W|Inferred from mutant phenotype] 26307168, Weak ECK125256964 naRNA3 4326105 4326181 reverse naRNA3 26307168, ECK125256959 naRNA2 4326205 4326281 reverse naRNA2 26307168, ECK125256969 naRNA1 4326305 4326381 reverse naRNA1 26307168, ECK120000703 yjdM b4108 4326399 4326734 reverse zinc ribbon domain-containing protein YjdM b4108 ECK120001190 rdcA b4109 4327135 4329363 forward regulator of diguanylate cyclase RdcA b4109 ECK120004321 rdcB b4110 4329360 4330238 forward regulator of diguanylate cyclase RdcB [EXP-IMP|W|Inferred from mutant phenotype] 31022167, Weak b4110 ECK120001560 proP b4111 4330502 4332004 forward osmolyte:H symporter ProP 11157932,11401581,11866514,11866515,12525168,14529293,14690427,15126461,15205426,19366597,20828170,22740696,2275537,26871755,28351917,28911185,2949137,3060036,7006756,7654759, b4111 ECK125135313 pmrR b4703 4332116 4332205 forward small regulatory membrane protein PmrR [EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ] 34017319, Weak b4703 ECK120001562 basS b4112 4332181 4333272 reverse sensor histidine kinase BasS 33411736,34234474, b4112 ECK120001563 basR b4113 4333282 4333950 reverse DNA-binding transcriptional dual regulator BasR [EXP-IDA|W|Inferred from direct assay],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 10373459,11222580,1482126,15522865,15556475,15569938,15659161,17686460,2157156,7565089,7699720,8098993, Weak b4113 ECK120001561 eptA b4114 4333947 4335590 reverse phosphoethanolamine transferase EptA 17362200,23372159, b4114 ECK120002306 adiC b4115 4335694 4337031 reverse arginine:agmatine antiporter 12867448,14594828, b4115 ECK120001892 adiY b4116 4337168 4337929 reverse DNA-binding transcriptional activator AdiY [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 8704970, Weak b4116 ECK120001457 adiA b4117 4338254 4340521 reverse arginine decarboxylase, degradative b4117 ECK120001208 melR b4118 4340720 4341628 reverse DNA-binding transcriptional dual regulator MelR 1445207,2684786,2830169,8010957, b4118 ECK120000570 melA b4119 4341911 4343266 forward α-galactosidase 3031590, b4119 ECK120000571 melB b4120 4343369 4344790 forward melibiose:H symporter 11695924,12421811,15449950,15736960,16139519,16822867,18572928,1872836,19366604,19706416,21135207,3004296,7703254,7929169,8428997,8428998, b4120 ECK120004322 yjdF b4121 4344929 4345558 reverse DUF2238 domain-containing inner membrane protein YjdF b4121 ECK120000350 fumB b4122 4345680 4347326 reverse fumarase B 1499335,16417494,2656658,5330664, b4122 ECK120000005 dcuB b4123 4347404 4348744 reverse anaerobic C4-dicarboxylate transporter DcuB 1512189,20860483, b4123 ECK120004323 dcuR b4124 4349315 4350034 reverse DNA-binding transcriptional activator DcuR [EXP-IGI-FUNC-COMPLEMENTATION|S|Inferred by functional complementation],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 9765574, Strong b4124 ECK120004324 dcuS b4125 4350031 4351662 reverse sensor histidine kinase DcuS b4125 ECK120004325 yjdI b4126 4351843 4352073 forward PF06902 family protein YjdI b4126 ECK120004326 yjdJ b4127 4352085 4352357 forward putative -acetyltransferase YjdJ b4127 ECK120004327 ghoS b4128 4352584 4352880 forward antitoxin of the GhoTS toxin-antitoxin system [EXP-IDA|W|Inferred from direct assay] 22941047, Weak b4128 ECK120016324 ghoT b4559 4352908 4353081 forward toxin of the GhoTS toxin-antitoxin system [EXP-IMP|W|Inferred from mutant phenotype] 22941047, Weak b4559 ECK120000546 lysU b4129 4353200 4354717 reverse lysine—tRNA ligase/ApA synthetase 16297624,170611,20571084,23208549,24736113,28641210,318645,320199,3280549,328487,3305502,4284804,4290754,4552089,4552090,6277395,6373723,6756470,7027957,779846,779847,786844,7896714,7932734,805427,807389,8152, b4129 ECK120002307 dtpC b4130 4354954 4356411 reverse dipeptide/tripeptide:H symporter DtpC 23110099,27916534, b4130 ECK120000127 cadA b4131 4356470 4358617 reverse lysine decarboxylase 1 b4131 ECK120000128 cadB b4132 4358697 4360031 reverse lysine:cadaverine antiporter 14982633,16877381, b4132 ECK120000129 cadC b4133 4360396 4361934 reverse DNA-binding transcriptional activator CadC [EXP-IMP|W|Inferred from mutant phenotype] 1370290,18086202,7830562, Weak b4133 ECK125240983 yjdQ b4654 4362191 4362353 reverse b4654 ECK120002506 pheU b4134 4362551 4362626 reverse tRNA-Phe(GAA) [AS-TAS|W|Traceable author statement] 7033244, Weak b4134 ECK120002069 yjdC b4135 4362733 4363308 reverse putative DNA-binding transcriptional regulator YjdC 19459971, b4135 ECK120002071 dsbD b4136 4363345 4365042 reverse thiol-disulfide exchange protein DsbD 10545108,11085993,11493705,11886218,12033924,12145197,12234918,12753926,15057279,16004871,16545842,16816179,17015672,17303162,17544440,18571669,19258316,21543317,21742866,22127524,24469455,7623667,7957865, b4136 ECK120002070 cutA b4137 4365018 4365356 reverse copper binding protein CutA b4137 ECK120001203 dcuA b4138 4365472 4366773 reverse C4-dicarboxylate transporter DcuA 1512189, b4138 ECK125303719 aspX b4825 4366839 4366951 reverse small regulatory RNA AspX [EXP-IMP|W|Inferred from mutant phenotype] 34210798, Weak b4825 ECK120000091 aspA b4139 4366891 4368327 reverse aspartate ammonia-lyase 3541901,9852003, b4139 ECK120004328 fxsA b4140 4368664 4369140 forward protein FxsA [EXP|W|Inferred from experiment],[EXP-IMP|W|Inferred from mutant phenotype] 10497016,10497017, Weak b4140 ECK120004329 yjeH b4141 4369156 4370412 reverse L-methionine/branched chain amino acid exporter b4141 ECK120000593 groS b4142 4370688 4370981 forward cochaperonin GroES 3017973,6460256, b4142 ECK120000592 groL b4143 4371025 4372671 forward chaperonin GroEL 10752609,15299422,26124125,26604310,26604318,27718375,28156097,28710336,29735733,379350,4561971,7904652,7911323,8096194,8571125,8760501, b4143 ECK120004330 yjeI b4144 4372809 4373162 forward DUF4156 domain-containing lipoprotein YjeI 32053772, b4144 ECK120004331 yjeJ b4145 4373365 4374234 reverse protein YjeJ b4145 ECK120004332 epmB b4146 4374629 4375657 reverse lysine 2,3-aminomutase b4146 ECK120002004 efp b4147 4375699 4376265 forward protein chain elongation factor EF-P [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 1956781,20823541,25364902,795670, Weak b4147 ECK120002571 ecnA b4410 4376317 4376442 forward entericidin A lipoprotein, antidote to entericidin B [EXP-IDA-UNPURIFIED-PROTEIN-NH|W|Assay of unpurified protein expressed in its native host] 15174130,19210615,32053772,9677290, Weak b4410 ECK120002651 ecnB b4411 4376553 4376699 forward bacteriolytic entericidin B lipoprotein [EXP-IDA-UNPURIFIED-PROTEIN-NH|W|Assay of unpurified protein expressed in its native host] 15174130,19210615,32053772,9677290,9829938, Weak b4411 ECK120001564 gdx b4148 4376875 4377192 forward guanidinium exporter 8096175, b4148 ECK120004333 blc b4149 4377189 4377722 reverse outer membrane lipoprotein Blc 11058749,12876315,15174130,32053772,32058942, b4149 ECK120000036 ampC b4150 4377811 4378944 reverse β-lactamase 28183996, b4150 ECK120000327 frdD b4151 4379007 4379366 reverse fumarate reductase membrane protein FrdD 8419359, b4151 ECK120000326 frdC b4152 4379377 4379772 reverse fumarate reductase membrane protein FrdC 28621879,8419359, b4152 ECK120000325 frdB b4153 4379783 4380517 reverse fumarate reductase iron-sulfur protein b4153 ECK120000324 frdA b4154 4380510 4382318 reverse fumarate reductase flavoprotein subunit 29610278, b4154 ECK120001191 epmA b4155 4382643 4383620 forward EF-P-lysine lysyltransferase b4155 ECK120002308 yjeM b4156 4383839 4385341 forward putative transporter YjeM 31438868, b4156 ECK120004334 yjeN b4157 4385393 4385707 forward uncharacterized protein YjeN b4157 ECK120004335 yjeO b4158 4385704 4386018 forward DUF2645 domain-containing inner membrane protein YjeO b4158 ECK120004336 mscM b4159 4386047 4389370 reverse miniconductance mechanosensitive channel MscM b4159 ECK120000766 psd b4160 4389392 4390360 reverse phosphatidylserine decarboxylase proenzyme 1495415,211116,322713,3535891,368058,4943977,5002558,6754694,7011377, b4160 ECK120004337 rsgA b4161 4390457 4391509 reverse ribosome small subunit-dependent GTPase A 19749383,24671761,26823481,27388791,29511080, b4161 ECK120004338 orn b4162 4391604 4392149 forward oligoribonuclease b4162 ECK120002480 glyV b4163 4392360 4392435 forward tRNA-Gly(GCC) b4163 ECK120002482 glyX b4164 4392472 4392547 forward tRNA-Gly(GCC) b4164 ECK120002483 glyY b4165 4392583 4392658 forward tRNA-Gly(GCC) b4165 ECK120048854 yjeV b4670 4392892 4392945 forward uncharacterized protein YjeV b4670 ECK120004339 queG b4166 4392928 4394067 reverse epoxyqueuosine reductase b4166 ECK120001694 nnr b4167 4394066 4395613 forward NAD(P)HX epimerase / NAD(P)HX dehydratase b4167 ECK120001693 tsaE b4168 4395585 4396046 forward N-L-threonylcarbamoyladenine synthase, TsaE subunit 20701780,22268863, b4168 ECK120001332 amiB b4169 4396065 4397402 forward -acetylmuramoyl-L-alanine amidase B 1102308,12399477,6133749,7511774, b4169 ECK120001254 mutL b4170 4397412 4399259 forward DNA mismatch repair protein MutL 25701376,31757945,33233554, b4170 ECK120000588 miaA b4171 4399252 4400202 forward tRNA dimethylallyltransferase 8371264, b4171 ECK120000431 hfq b4172 4400288 4400596 forward RNA-binding protein Hfq 14526009,28334975, b4172 ECK120000430 hflX b4173 4400672 4401952 forward ribosome rescue factor HflX [EXP-IDA|W|Inferred from direct assay] 22750478,26458047,2824788,34427514,7984093, Weak b4173 ECK120000429 hflK b4174 4402038 4403297 forward regulator of FtsH protease [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host],[EXP-IGI|W|Inferred from genetic interaction] 8947034,9159109, Strong b4174 ECK120000428 hflC b4175 4403300 4404304 forward regulator of FtsH protease [IDA-PURIFIED-PROTEIN-NH|S|Assay of protein purified to homogeneity from its native host],[EXP-IGI|W|Inferred from genetic interaction] 8947034,9159109, Strong b4175 ECK120004340 yjeT b4176 4404386 4404583 forward DUF2065 domain-containing protein YjeT b4176 ECK120000781 purA b4177 4404687 4405985 forward adenylosuccinate synthetase b4177 ECK120001192 nsrR b4178 4406190 4406615 forward DNA-binding transcriptional regulator NsrR b4178 ECK120001234 rnr b4179 4406654 4409095 forward RNase R 11248028,14527658,18337246,19161851,21445001,22328678,22609921,22957931,29180590,33503254,779788, b4179 ECK120004341 rlmB b4180 4409275 4410006 forward 23S rRNA 2'--ribose G2251 methyltransferase b4180 ECK120004342 yjfI b4181 4410133 4410534 forward DUF2170 domain-containing protein YjfI b4181 ECK120004343 yjfJ b4182 4410553 4411251 forward PspA family protein YjfJ b4182 ECK120004344 yjfK b4183 4411302 4411961 forward DUF2491 domain-containing protein YjfK b4183 ECK120004345 yjfL b4184 4411979 4412377 forward DUF350 domain-containing inner membrane protein YjfL b4184 ECK120004346 yjfM b4185 4412387 4413025 forward DUF1190 domain-containing protein YjfM b4185 ECK120001746 yjfC b4186 4413028 4414191 forward putative acid—amine ligase YjfC b4186 ECK120001745 aidB b4187 4414275 4415900 forward putative acyl-CoA dehydrogenase AidB 15977811, b4187 ECK120004347 yjfN b4188 4416017 4416292 reverse protease activator YjfN [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 12123445,15690043,19246752,28947671, Weak b4188 ECK120004348 bsmA b4189 4416441 4416770 reverse DUF1471 domain-containing putative lipoprotein BsmA [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 19833773,32053772, Weak b4189 ECK120004349 yjfP b4190 4416952 4417701 forward carboxylesterase b4190 ECK120004350 ulaR b4191 4417698 4418453 reverse DNA-binding transcriptional repressor UlaR [EXP-IEP|W|Inferred from expression pattern] 12374842, Weak b4191 ECK120004351 ulaG b4192 4418561 4419625 reverse L-ascorbate-6-phosphate lactonase 12374842, b4192 ECK120004352 ulaA b4193 4419980 4421377 forward L-ascorbate specific PTS enzyme IIC component 11741871, b4193 ECK120002309 ulaB b4194 4421393 4421698 forward L-ascorbate specific PTS enzyme IIB component 11741871, b4194 ECK120002310 ulaC b4195 4421708 4422172 forward L-ascorbate specific PTS enzyme IIA component b4195 ECK120004353 ulaD b4196 4422186 4422836 forward 3-keto-L-gulonate-6-phosphate decarboxylase UlaD 11741871, b4196 ECK120004354 ulaE b4197 4422846 4423700 forward L-ribulose-5-phosphate 3-epimerase UlaE 11741871, b4197 ECK120004355 ulaF b4198 4423700 4424386 forward L-ribulose-5-phosphate 4-epimerase UlaF b4198 ECK120004356 yjfY b4199 4424516 4424791 reverse DUF1471 domain-containing protein YjfY b4199 ECK120000896 rpsF b4200 4425118 4425513 forward 30S ribosomal subunit protein S6 21030658,25007658,3373530, b4200 ECK120000755 priB b4201 4425520 4425834 forward primosomal replication protein N 1646811,1856227,27718375, b4201 ECK120000908 rpsR b4202 4425839 4426066 forward 30S ribosomal subunit protein S18 3373530, b4202 ECK120000861 rplI b4203 4426108 4426557 forward 50S ribosomal subunit protein L9 11474114,11563917,16272117,16930151,1702198,18514735,1939233,21596992,21757758,23517076,2578985,2581817,340925,342903,3528756,3541786,366612,414209,6341200,6358224,6359156,6402016,6450872,68433,827440, b4203 ECK120004357 yjfZ b4204 4426628 4427422 reverse DUF2686 domain-containing protein YjfZ b4204 ECK120004358 ytfA b4205 4427694 4428095 forward putative transcriptional regulator YtfA b4205 ECK120004359 ytfB b4206 4428079 4428717 reverse cell division protein YtfB b4206 ECK120004360 fklB b4207 4428935 4429555 forward peptidyl-prolyl isomerase FklB b4207 ECK120002311 cycA b4208 4429864 4431276 forward D-serine/alanine/glycine/:Hsymporter 32518189,4583203,7894704, b4208 ECK120004361 ytfE b4209 4431321 4431983 reverse iron-sulfur cluster repair protein YtfE [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 15546870,16261196,16553864,17289666,29330894, Weak b4209 ECK120004362 ytfF b4210 4432091 4433056 reverse inner membrane protein YtfF 21531828,31438868, b4210 ECK120004363 qorB b4211 4433164 4434024 reverse NAD(P)H:quinone oxidoreductase b4211 ECK120004364 ytfH b4212 4434113 4434493 forward putative transcriptional regulator YtfH b4212 ECK120000156 cpdB b4213 4434622 4436565 reverse 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase 33923386,4300709,6251162, b4213 ECK120000039 cysQ b4214 4436755 4437495 forward 3'(2'),5'-bisphosphate nucleotidase b4214 ECK120004365 ytfI b4215 4437707 4438645 forward protein YtfI b4215 ECK120004366 ytfJ b4216 4438708 4439262 reverse PF09695 family protein YtfJ 24891291, b4216 ECK120004367 ytfK b4217 4439587 4439793 forward stringent response modulator YtfK b4217 ECK120004368 paeA b4218 4439872 4441215 reverse putative cadaverine/putrescine exporter 31438868, b4218 ECK125135311 4441225 4441330 reverse small RNA ECK120001397 msrA b4219 4441538 4442176 reverse methionine sulfoxide reductase A 10360685,10569933,11116194,11860363,1468111,15756465,16505957,27625316,7017726, b4219 ECK120004369 tamA b4220 4442382 4444115 forward translocation and assembly module subunit TamA [EXP-IMP|W|Inferred from mutant phenotype] 22466966,26427691, Weak b4220 ECK120004370 tamB b4221 4444112 4447891 forward translocation and assembly module subunit TamB [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 22125496,22466966,25195908,34781743, Weak b4221 ECK120004371 ytfP b4222 4447894 4448235 forward γ-glutamylamine cyclotransferase family protein YtfP b4222 ECK120001193 yzfA b4223 4447976 4448245 reverse b4223 ECK120001225 chpS b4224 4448447 4448698 forward ChpS antitoxin of the ChpB-ChpS toxin-antitoxin system 3525538, b4224 ECK120002001 chpB b4225 4448692 4449042 forward endoribonuclease toxin ChpB b4225 ECK120000746 ppa b4226 4449122 4449652 reverse inorganic pyrophosphatase 2160278,2848015, b4226 ECK120002312 ytfQ b4227 4449962 4450918 forward galactofuranose ABC transporter periplasmic binding protein b4227 ECK120002313 ytfR b4485 4451058 4452560 forward galactofuranose ABC transporter putative ATP binding subunit b4228,b4229,b4485 ECK120002314 ytfT b4230 4452571 4453596 forward galactofuranose ABC transporter putative membrane subunit YtfT 31438868, b4230 ECK120002293 yjfF b4231 4453583 4454578 forward galactofuranose ABC transporter putative membrane subunit YjtF 31438868, b4231 ECK120000277 fbp b4232 4454611 4455609 reverse fructose-1,6-bisphosphatase 1 b4232 ECK120002294 mpl b4233 4455785 4457158 forward UDP--2,6-diaminoheptanedioate ligase 25355616, b4233 ECK120001376 yjgA b4234 4457314 4457865 reverse putative ribosome biogenesis factor YjgA [EXP-IDA|W|Inferred from direct assay] 33639093, Weak b4234 ECK120000732 tldE b4235 4457959 4459311 forward metalloprotease subunit TldE b4235 ECK120002567 cybC b4236 4459488 4459855 forward b4236 ECK120004452 nrdG b4237 4459900 4460364 reverse anaerobic ribonucleoside-triphosphate reductase activating protein 12206460,7852304, b4237 ECK120001382 nrdD b4238 4460522 4462660 reverse anaerobic ribonucleoside-triphosphate reductase 10531327,1460049,1460050,1953774,24827372,8621608,9305874, b4238 ECK120001368 treC b4239 4463054 4464709 reverse trehalose-6-phosphate hydrolase b4239 ECK120002029 treB b4240 4464759 4466180 reverse trehalose-specific PTS enzyme IIBC component b4240 ECK120002090 treR b4241 4466299 4467246 reverse DNA-binding transcriptional repressor TreR b4241 ECK125122027 mgtL b4702 4467431 4467484 forward leader peptide MgtL [EXP-IDA|W|Inferred from direct assay] 29100053, Weak b4702 ECK120002316 mgtA b4242 4467625 4470321 forward Mg importing P-type ATPase b4242 ECK120004372 ridA b4243 4470527 4470913 reverse enamine/imine deaminase, redox-regulated chaperone 11151008, b4243 ECK120000802 pyrI b4244 4470986 4471447 reverse aspartate carbamoyltransferase, PyrI subunit 4872216, b4244 ECK120000796 pyrB b4245 4471460 4472395 reverse aspartate carbamoyltransferase catalytic subunit b4245 ECK120001252 pyrL b4246 4472399 4472533 reverse operon leader peptide [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 2991885, Weak b4246 ECK120004373 Phantom Gene b4247 4472513 4472845 forward b4247 ECK120004374 yjgH b4248 4472814 4473209 reverse RutC family protein YjgH b4248 ECK120004375 bdcA b4249 4473340 4474053 reverse c-di-GMP-binding biofilm dispersal mediator protein b4249 ECK120004377 bdcR b4251 4474124 4474717 forward putative transcriptional regulator BdcR [EXP-IMP|W|Inferred from mutant phenotype] 21059164, Weak b4251 ECK120004376 Phantom Gene b4250 4474227 4474391 forward b4250 ECK120004378 tabA b4252 4474862 4475314 forward DUF386 domain-containing toxin-antitoxin biofilm protein TabA [EXP-IMP|W|Inferred from mutant phenotype] Weak b4252 ECK120004379 yjgL b4253 4475437 4477251 forward protein YjgL b4253 ECK120000065 argI b4254 4477307 4478311 reverse ornithine carbamoyltransferase ArgI b4254 ECK120004380 rraB b4255 4478473 4478889 forward ribonuclease E inhibitor protein B b4255 ECK120004381 yjgM b4256 4479034 4479537 reverse putative -acetyltransferase YjgM b4256 ECK120004382 yjgN b4257 4479730 4480926 forward inner membrane protein YjgN b4257 ECK120001056 valS b4258 4480982 4483837 reverse valine—tRNA ligase 19574213,20483314, b4258 ECK120001379 holC b4259 4483837 4484280 reverse DNA polymerase III subunit χ 27150717,27718375,33531410,8246893,8389364, b4259 ECK120000686 pepA b4260 4484440 4485951 reverse aminopeptidase A/I 14741201, b4260 ECK125303705 ytgB b4822 4486043 4486099 forward protein YtgB b4822 ECK125286424 ytgA b4800 4486105 4486155 forward protein YtgA b4800 ECK120004383 lptF b4261 4486218 4487318 forward lipopolysaccharide transport system protein LptF 27529623, b4261 ECK120004384 lptG b4262 4487318 4488400 forward lipopolysaccharide transport system protein LptG b4262 ECK120004385 yjgR b4263 4488561 4490063 reverse DUF853 domain-containing protein YjgR b4263 ECK120004386 idnR b4264 4490141 4491139 reverse DNA-binding transcriptional dual regulator IdnR 11441462, b4264 ECK120002317 idnT b4265 4491206 4492525 reverse L-idonate/5-ketogluconate/gluconate transporter b4265 ECK120004387 idnO b4266 4492587 4493351 reverse 5-keto-D-gluconate 5-reductase b4266 ECK120004388 idnD b4267 4493375 4494406 reverse L-idonate 5-dehydrogenase b4267 ECK120002051 idnK b4268 4494623 4495186 forward D-gluconate kinase, thermosensitive 11430650,22688914,9151423, b4268 ECK120001400 ahr b4269 4495190 4496209 reverse NADPH-dependent aldehyde reductase Ahr b4269 ECK120002495 leuX b4270 4496405 4496489 forward tRNA-Leu(CAA) [AS-TAS|W|Traceable author statement] 19906695,7033244, Weak b4270 ECK120002232 intB b4271 4496750 4497940 forward KpLE2 phage-like element; putative integrase b4271 ECK120023922 insCD6 4498272 4499500 forward IS2 element transposase InsAB' 9302014, ECK120004389 insC6 b4272 4498272 4498637 forward KpLE2 phage-like element; IS2 insertion element repressor InsA b4272 ECK120004390 insD6 b4273 4498595 4499500 forward KpLE2 phage-like element; IS2 insertion element protein InsB b4273 ECK120004393 yjgX b4575 4499593 4500791 reverse KpLE2 phage-like element; putative phosphoethanolamine transferase YjgX, N-terminal fragment b4275,b4276,b4560,b4575 ECK120004391 yjgW b4274 4499599 4499934 forward b4274 ECK120004394 yjgZ b4277 4501260 4501589 forward KpLE2 phage-like element; uncharacterized protein YjgZ b4277 ECK120004395 insG b4278 4502103 4503431 reverse KpLE2 phage-like element; IS putative transposase 2558284,2561211,2564160,2870515,2996976,3030884,392235,6096210,6248723,6248724,6268937,6270501,6271469,6283315,7934941, b4278 ECK120002318 nanX b4279 4504058 4505275 forward sialic acid transporter NanX 32669363, b4279 ECK120004396 nanY b4280 4505287 4506405 forward KpLE2 phage-like element; 2,7-anhydro--acetylneuraminate hydratase b4280 ECK120033233 ythA b4655 4506448 4506573 forward KpLE2 phage-like element; uncharacterized protein YthA b4655 ECK120004397 yjhD b4281 4506626 4506856 reverse KpLE2 phage-like element; surface adhesin E-like protein b4281 ECK120004398 yjhE b4282 4506861 4507109 forward KpLE2 phage-like element; putative membrane protein (pseudogene) 27363198, b4282 ECK120004400 insI3 b4284 4507466 4508617 reverse KpLE2 phage-like element; IS30 transposase b4284 ECK120026457 insM b4561 4508684 4508942 reverse b4561 ECK120004402 yjhV b4286 4509804 4510133 forward KpLE2 phage-like element; putative uncharacterized protein YjhV b4286 ECK120000284 fecE b4287 4510690 4511457 reverse ferric citrate ABC transporter ATP binding subunit b4287 ECK120000283 fecD b4288 4511458 4512414 reverse ferric citrate ABC transporter membrane subunit FecD b4288 ECK120000282 fecC b4289 4512411 4513409 reverse ferric citrate ABC transporter membrane subunit FecC b4289 ECK120000281 fecB b4290 4513406 4514308 reverse ferric citrate ABC transporter periplasmic binding protein 17660286,21194366,2651410,2836368,6268411,6376472, b4290 ECK120000280 fecA b4291 4514353 4516677 reverse ferric citrate outer membrane transporter 11566987,15292131,16718599,17186377,17606918,22960041,2836368,29468195,29669516,33717488,7734925,8471822,9573190, b4291 ECK120000286 fecR b4292 4516764 4517717 reverse ferric citrate regulator FecR [EXP-IMP|W|Inferred from mutant phenotype] 12813067,16193283,16923915,17673165,2254251,7752886,7768834,8596456,9575233, Weak b4292 ECK120000285 fecI b4293 4517714 4518235 reverse RNA polymerase sigma factor FecI [EXP-IDA|W|Inferred from direct assay] 12644513,16193283,21396442,23992563,7729419,8596456,9575233, Weak b4293 ECK125286399 ykiE b4801 4518372 4518440 forward protein YkiE b4801 ECK120004403 insA7 b4294 4518527 4518802 forward KpLE2 phage-like element; IS1 repressor protein InsA [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 1849492, Weak b4294 ECK120026458 insB7 b4576 4518721 4519224 forward b4563,b4564,b4576 ECK120004404 yjhU b4295 4519338 4520324 reverse KpLE2 phage-like element; putative DNA-binding transcriptional regulator YjhU [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence] 15556475,29914953, Weak b4295 ECK120002319 yjhF b4296 4520671 4522020 reverse KpLE2 phage-like element; putative transporter YjhF b4296 ECK120004405 yjhG b4297 4522127 4524094 reverse KpLE2 phage-like element; D-xylonate dehydratase 24391520,27702485, b4297 ECK120004406 yjhH b4298 4524105 4525010 reverse KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase 26854668,27702485,28926911,29392388, b4298 ECK120004407 yjhI b4299 4525015 4525803 reverse KpLE2 phage-like element; putative DNA-binding transcriptional regulator YjhI [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 15556475, Weak b4299 ECK120004408 sgcR b4300 4526106 4526888 reverse KpLE2 phage-like element; putative DNA-binding transcriptional regulator SgcR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475,15608167, Weak b4300 ECK120004409 sgcE b4301 4526905 4527537 reverse KpLE2 phage-like element; putative epimerase SgcE b4301 ECK120002320 sgcA b4302 4527549 4527980 reverse putative PTS enzyme IIA component SgcA b4302 ECK120030092 ryjB b4624 4527977 4528066 forward small RNA RyjB [EXP-IMP|W|Inferred from mutant phenotype] 31744883,34967409, Weak b4624 ECK120004410 sgcQ b4303 4528111 4528917 reverse KpLE2 phage-like element; putative nucleoside triphosphatase b4303 ECK120002321 sgcC b4304 4528930 4530243 reverse putative PTS enzyme IIC component SgcC b4304 ECK120015144 sgcB b4565 4530255 4530533 reverse putative PTS enzyme IIB component SgcB b4565 ECK120002322 sgcX b4305 4530530 4531651 reverse KpLE2 phage-like element; putative endoglucanase with Zn-dependent exopeptidase domain b4305 ECK125240984 yjhY b4656 4532050 4532310 reverse b4656 ECK120004411 yjhP b4306 4532437 4533183 reverse KpLE2 phage-like element; putative methyltransferase YjhP b4306 ECK120004412 yjhQ b4307 4533239 4533784 reverse KpLE2 phage-like element; putative acetyltransferase TopAI antitoxin YjhQ [EXP-IMP|W|Inferred from mutant phenotype] 26553797, Weak b4307 ECK120016325 topAI b4566 4533796 4534053 reverse KpLE2 phage-like element; toxin of the TopAI-YjhQ toxin-antitoxin system, TopA inhibitor [EXP-IDA|W|Inferred from direct assay] 26553797, Weak b4566 ECK125240985 yjhZ b4657 4534430 4534675 reverse KpLE2 phage-like element; putative acetyltransferase YjhZ b4657 ECK120004413 yjhR b4308 4535015 4536031 forward KpLE2 phage-like element; PLD-like domain-containing protein YjhR b4308 ECK125286411 ythB b4802 4536597 4536695 forward protein YthB b4802 ECK120004414 nanS b4309 4536614 4537594 reverse -acetylneuraminate esterase b4309 ECK120004415 nanM b4310 4537659 4538765 reverse -acetylneuraminate mutarotase b4310 ECK120004416 nanC b4311 4538785 4539501 reverse -acetylneuraminate outer membrane channel 12192075,12890032,19796645,24147565,24161028, b4311 ECK120000303 fimB b4312 4540957 4541559 forward Type 1 fimbriae regulatory protein FimB [EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ] 10648536,10781567,11881836,16988236,8878036,9108285, Weak b4312 ECK120000306 fimE b4313 4542037 4542633 forward regulator for fimA [EXP-IDA-UNPURIFIED-PROTEIN|W|Assay of unpurified protein ] 10648536,11881836,16988236,7814281,8878036, Weak b4313 ECK120000302 fimA b4314 4543115 4543663 forward type 1 fimbriae major subunit 21816158,24184277,31126987,33198386, b4314 ECK120001899 fimI b4315 4543728 4544267 forward putative fimbrial protein FimI b4315 ECK120000304 fimC b4316 4544304 4545029 forward type 1 fimbriae periplasmic chaperone [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 10201401,10446051,10859353,10995223, Weak b4316 ECK120000305 fimD b4317 4545096 4547732 forward type I fimbriae usher protein [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 18369105,21637253,21784935, Weak b4317 ECK120000307 fimF b4318 4547742 4548272 forward type 1 fimbriae minor subunit FimF b4318 ECK120000308 fimG b4319 4548285 4548788 forward type 1 fimbriae minor subunit FimG b4319 ECK120000309 fimH b4320 4548808 4549710 forward type 1 fimbriae D-mannose specific adhesin [EXP-IDA-PART-PURIFIED-PROTEIN-NH|W|Assay of protein partially-purified from its native host],[EXP-IMP|W|Inferred from mutant phenotype] 1971261,33198386,7905476, Weak b4320 ECK120002323 gntP b4321 4549953 4551296 reverse fructuronate transporter b4321 ECK120001055 uxuA b4322 4551636 4552820 forward D-mannonate dehydratase 7007313, b4322 ECK120002446 uxuB b4323 4552901 4554361 forward D-mannonate oxidoreductase b4323 ECK120002447 uxuR b4324 4554576 4555349 forward DNA-binding transcriptional repressor UxuR [EXP-IEP|W|Inferred from expression pattern] 2823062,3083215, Weak b4324 ECK120004417 yjiC b4325 4555490 4556320 reverse DUF2686 domain-containing protein YjiC b4325 ECK125256971 ytiC b4720 4556574 4556675 forward protein YtiC b4720 ECK125256961 ytiD b4721 4556654 4556797 forward protein YtiD b4721 ECK125256967 idlP b4722 4556913 4556996 forward leader peptide b4722 ECK120004418 iraD b4326 4556993 4557385 forward anti-adaptor protein IraD [EXP-IDA|W|Inferred from direct assay] 18383615,29802191,33346011, Weak b4326 ECK120004419 hypT b4327 4557378 4558289 reverse DNA-binding transcriptional dual regulator HypT b4327 ECK120004420 iadA b4328 4558354 4559526 reverse isoaspartyl dipeptidase b4328 ECK120004421 yjiG b4329 4559539 4560000 reverse Gate family protein YjiG b4329 ECK120004422 yjiH b4330 4559997 4560680 reverse uncharacterized protein YjiH b4330 ECK120004423 kptA b4331 4560930 4561484 forward RNA 2'-phosphotransferase [EXP-IDA|W|Inferred from direct assay] 11705403,9915792, Weak b4331 ECK120004424 yjiJ b4332 4561497 4562675 reverse putative transporter YjiJ b4332 ECK120004425 yjiK b4333 4562743 4563603 reverse PF06977 family protein YjiK 31608580,32053772, b4333 ECK125229293 ytiA b4715 4563668 4563925 reverse uncharacterized protein YtiA b4715 ECK120004426 yjiL b4334 4563922 4564689 reverse putative ATPase, activator of (R)-hydroxyglutaryl-CoA dehdratase 16397293, b4334 ECK120004427 yjiM b4335 4564699 4565850 reverse putative dehydratase subunit b4335 ECK120004428 yjiN b4336 4565966 4567246 reverse DUF445 domain-containing protein YjiN b4336 ECK120002324 mdtM b4337 4567287 4568519 reverse multidrug efflux pump / bile salt:H antiporter 19451626,27025617,27050393,29574104,31251753,31438868,9079913, b4337 ECK125303711 ytiE b4823 4568692 4568727 reverse protein YtiE b4823 ECK120004429 rpnD b4584 4568998 4569918 forward putative inactive recombination-promoting nuclease-like protein RpnD [EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 16385049, Weak b4338,b4339,b4584 ECK120004431 yjiR b4340 4570162 4571574 reverse fused putative DNA-binding transcriptional regulator/putative aminotransferase YjiR [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10734204,15556475,26162088, Weak b4340 ECK120004432 yjiS b4341 4571751 4571915 forward DUF1127 domain-containing protein YjiS b4341 ECK120004433 yjiT b4342 4572414 4573931 forward putative uncharacterized protein YjiT b4342 ECK120001353 yjiV b4486 4574135 4576855 forward putative uncharacterized protein YjiV b4343,b4344,b4486 ECK120000568 mcrC b4345 4576912 4577958 reverse Type IV methyl-directed restriction enzyme EcoKMcrBC subunit 11244066,11955073,1987114,30531155,31296862,9348106, b4345 ECK120000567 mcrB b4346 4577958 4579337 reverse McrB 1649819,1987114,2548920,26727463,3031021,30521042,30904393,31296862,767337,9736625, b4346 ECK120000567 mcrB b4346 4577958 4579337 reverse Type IV methyl-directed restriction enzyme EcoKMcrB subunit 1649819,1987114,2548920,26727463,3031021,30521042,30904393,31296862,767337,9736625, b4346 ECK120004434 symE b4347 4579499 4579840 reverse nucleoid-associated protein SymE b4347 ECK120030093 symR b4625 4579835 4579911 forward small regulatory RNA antitoxin SymR [EXP-IMP|W|Inferred from mutant phenotype] 17462020, Weak b4625 ECK120000453 hsdS b4348 4580068 4581462 reverse type I restriction enzyme EcoKI specificity subunit b4348 ECK120000451 hsdM b4349 4581459 4583048 reverse type I restriction enzyme EcoKI methylase subunit b4349 ECK120000452 hsdR b4350 4583249 4586761 reverse type I restriction enzyme EcoKI endonuclease subunit b4350 ECK120000605 mrr b4351 4586949 4587863 forward Type IV methyl-directed restriction enzyme EcoKMrr [EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 11313145,16313623,1649819,1650347,1830580,1851562,2013582,21504983,24002639,3036779,7607496,7928948, Weak b4351 ECK120000018 yjiA b4352 4587909 4588865 reverse P-loop guanosine triphosphatase YjiA 19822009,34302342, b4352 ECK120004435 yjiX b4353 4588876 4589079 reverse PF04328 family protein YjiX b4353 ECK120004436 btsT b4354 4589129 4591279 reverse pyruvate:H symporter 23818977,29358499,3025181,30420452,33260635,33721833,4349657,4864638, b4354 ECK120001023 tsr b4355 4591657 4593312 forward methyl-accepting chemotaxis protein Tsr 6402709, b4355 ECK120002325 lgoT b4356 4593361 4594722 reverse galactonate:H+ symporter b4356 ECK120004437 lgoR b4357 4594937 4595851 reverse putative DNA-binding transcriptional regulator LgoR [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 15556475,17088549, Weak b4357 ECK120004438 lgoD b4358 4595990 4597012 forward L-galactonate oxidoreductase [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence],[EXP-IEP|W|Inferred from expression pattern],[EXP-IMP|W|Inferred from mutant phenotype] 17088549,24861318, Weak b4358 ECK120002326 opgB b4359 4597150 4599441 reverse phosphoglycerol transferase I b4359 ECK120001194 yjjA b4360 4599695 4600189 reverse DUF2501 domain-containing protein YjjA b4360 ECK120000231 dnaC b4361 4600238 4600975 reverse DNA replication protein DnaC [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 12906810,16036556,2536713,6292204, Weak b4361 ECK120000238 dnaT b4362 4600978 4601517 reverse primosomal protein DnaT b4362 ECK120001195 yjjB b4363 4601624 4602097 reverse putative succinate exporter YjjB b4363 ECK120004439 yjjP b4364 4602088 4602858 reverse putative succinate exporter YjjP 31438868, b4364 ECK120004440 yjjQ b4365 4603477 4604202 forward DNA-binding transcriptional repressor YjjQ [EXP-IDA|W|Inferred from direct assay],[EXP-IEP|W|Inferred from expression pattern],[COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 15556475,17846588,26078445, Weak b4365 ECK120004441 bglJ b4366 4604160 4604837 forward DNA-binding transcriptional regulator BglJ [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 15556475,16207917,27718375,8725214, Weak b4366 ECK120004442 fhuF b4367 4604875 4605663 reverse ferric-siderophore reductase FhuF [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 14756576,9990318, Weak b4367 ECK120016326 yjjZ b4567 4605804 4606040 forward DUF1435 domain-containing protein YjjZ b4567 ECK120002493 leuV b4368 4606079 4606165 reverse tRNA-Leu(CAG) [AS-TAS|W|Traceable author statement] 7033244, Weak b4368 ECK120002489 leuP b4369 4606200 4606286 reverse tRNA-Leu(CAG) [AS-TAS|W|Traceable author statement] 7033244, Weak b4369 ECK120002490 leuQ b4370 4606315 4606401 reverse tRNA-Leu(CAG) [AS-TAS|W|Traceable author statement] 7033244, Weak b4370 ECK120004443 rsmC b4371 4606669 4607700 reverse 16S rRNA mG1207 methyltransferase 11053259, b4371 ECK120001380 holD b4372 4607803 4608216 forward DNA polymerase III subunit ψ 27718375,34070637,8366044,8389364, b4372 ECK120000841 rimI b4373 4608185 4608631 forward protein -acetyltransferase RimI b4373 ECK120002019 yjjG b4374 4608646 4609323 forward pyrimidine 5'-nucleotidase YjjG 30327558, b4374 ECK120002018 prfC b4375 4609414 4611003 forward peptide chain release factor RF3 [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity] 10681447,11595190,12105207,12859903,15547251,17293419,19761774,21903932,22326347,24798339,32569619,7559341,8587108,8682777,9045840,9523014,9705149,9927432, Weak b4375 ECK120001358 osmY b4376 4611396 4612001 forward periplasmic chaperone OsmY [EXP-IEP|W|Inferred from expression pattern],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype] 1317380,15099515,18425732,26003922,7476160,7934831,8253679, Weak b4376 ECK120016327 ytjA b4568 4612128 4612289 forward DUF1328 domain-containing protein YtjA b4568 ECK120004444 yjjU b4377 4612411 4613484 forward putative patatin-like phospholipase YjjU b4377 ECK120004445 yjjV b4378 4613481 4614260 forward putative metal-dependent hydrolase YjjV [COMP-HINF-FN-FROM-SEQ|W|Human inference of function from sequence] 10747959, Weak b4378 ECK120004446 yjjW b4379 4614680 4615543 reverse putative glycyl-radical enzyme activating enzyme YjjW b4379 ECK120002066 yjjI b4380 4615515 4617065 reverse DUF3029 domain-containing protein YjjI [COMP-HINF|W|Inferred by a human based on computational evidence] 22144874, Weak b4380 ECK120000215 deoC b4381 4617323 4618102 forward deoxyribose-phosphate aldolase 1089630,30155096,4860428,4877128,5329976, b4381 ECK120000213 deoA b4382 4618229 4619551 forward thymidine phosphorylase 1089630,4862197, b4382 ECK120000214 deoB b4383 4619603 4620826 forward phosphopentomutase 10420269,10923257,11436549,11898608,12391882,12700258,15865284,186698,22122981,25161724,361716,369945,384146,4876138,4904508,4929284,4934066,6286410,6780756,810659,8647423,9480212,9929827, b4383 ECK120000216 deoD b4384 4620883 4621602 forward purine nucleoside phosphorylase b4384 ECK120002217 yjjJ b4385 4621769 4623100 forward toxin YjjJ [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IMP|W|Inferred from mutant phenotype] 15556475,28430938, Weak b4385 ECK120001730 lplA b4386 4623101 4624117 reverse lipoate—protein ligase A 13549404,1765143,21209092,25303731,9445386, b4386 ECK120000940 ytjB b4387 4624145 4624789 reverse probable inner membrane protein Smp b4387 ECK120000934 serB b4388 4624895 4625863 forward phosphoserine phosphatase 24646179,26884172,31557000, b4388 ECK120001269 radA b4389 4625912 4627294 forward DNA recombination protein [EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IMP|W|Inferred from mutant phenotype],[EXP-IGI|W|Inferred from genetic interaction] 12446634,26845522,28581365,3526390,6754650,9141693, Weak b4389 ECK120001306 nadR b4390 4627315 4628547 forward DNA-binding transcriptional repressor/NMN adenylyltransferase NadR b4390 ECK120002218 ettA b4391 4628855 4630522 reverse energy-dependent translational throttle protein EttA [EXP-IDA|W|Inferred from direct assay],[EXP-IMP|W|Inferred from mutant phenotype] 24389465,24389466,24391520,28911185,30597160,9593292, Weak b4391 ECK120000939 slt b4392 4630733 4632670 forward soluble lytic murein transglycosylase 10572120,11139297,12399477,15793119,2695826,3888619,6988211,6998964,7018908, b4392 ECK120001018 trpR b4393 4632760 4633086 forward DNA-binding transcriptional repressor TrpR 1740124,1935980,2182120,2207078,3290685,3600756,7001368,7012834,8176748, b4393 ECK120002327 yjjX b4394 4633233 4633745 reverse inosine/xanthosine triphosphatase 30168191, b4394 ECK120002060 ytjC b4395 4633797 4634444 forward putative phosphatase 21332126, b4395 ECK120001334 rob b4396 4634441 4635310 reverse DNA-binding transcriptional dual regulator Rob [EXP|W|Inferred from experiment] 7896685,8449900, Weak b4396 ECK120001196 creA b4397 4635521 4635994 forward PF05981 family protein CreA b4397 ECK120001197 creB b4398 4636007 4636696 forward DNA-binding transcriptional regulator CreB 1482126,2157156,7699720,7855419,8098993, b4398 ECK120000721 creC b4399 4636696 4638120 forward sensory histidine kinase CreC 3531171, b4399 ECK120000141 creD b4400 4638178 4639530 forward putative inner membrane protein CreD b4400 ECK120000057 arcA b4401 4639590 4640306 reverse DNA-binding transcriptional dual regulator ArcA [COMP-AINF-FN-FROM-SEQ|W|Automated inference of function from sequence],[EXP-IDA-PURIFIED-PROTEIN|W|Assay of protein purified to homogeneity],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W|Gene expression analysis] 12486057,1482126,16849788,2157156,2984198,7699720,8098993, Weak b4401 ECK120004447 yjjY b4402 4640402 4640542 forward uncharacterized protein YjjY b4402 ECK125303718 ytjE b4824 4640718 4640771 forward protein YtjE b4824 ECK120002186 yjtD b4403 4640942 4641628 forward putative tRNA/rRNA methyltransferase YjtD 8871555, b4403 ECK120001964 yejO b2190 adhesin-like autotransporter YejO 15659678,20447993, b2190 ECK120003287 lomR b4570 Rac prophage; protein LomR_1 b1369,b1371,b4570 ECK120002835 yaiT b4580 putative autotransporter YaiT b0371,b0374,b4580 ECK120001080 crl b0240 RNA polymerase holoenzyme assembly factor Crl 15898075,16352847,29229758, b0240 ECK120002672 ackB ECK120004399 insO b4623 KpLE2 phage-like element; IS911B regulator fragment b4283,b4285,b4562,b4623 ECK120000652 nmpC b0553 DLP12 prophage; putative outer membrane porin NmpC 3017988,8057841, b0553 ECK120003661 yoeA b4582 CP4-44 prophage; TonB-dependent receptor plug domain-containing protein YoeA b1995,b1998,b4582 ECK120002677 dgd D-galactose 1-dehydrogenase 181526, ECK120002906 renD b0542 DLP12 prophage; protein RenD b0542 ECK120004141 yqiG b3046 putative outer membrane usher protein YqiG 20345943,21344461,23382825,24025676, b3046 ECK120002630 alaB glutamate—pyruvate aminotransferase AlaB 396446,4146872, ECK120002828 yaiX b4579 putative acyltransferase, N-terminal fragment b0359,b0362,b4579 ECK120003316 ydbA b4492 putative outer membrane protein, N-terminal fragment b1401,b1405,b4492 ECK120002058 gatR b4498 DNA-binding transcriptional repressor GatR, N-terminal fragment 1661252,7772602, b2087,b2090,b4498 ECK120002122 yhiS b3504 putative uncharacterized protein YhiS b3504 ECK120004218 yhcE b4569 putative uncharacterized protein YhcE 21344461,23382825, b3217,b4549,b4569 ECK120004300 yrhA b3443 putative uncharacterized protein YrhA b3443 ECK120001911 wbbL b4571 interrupted rhamnosyltransferase WbbL b2031,b4540,b4571 ECK125135293 Pseudo Gene ECK120002750 insN b4587 CP4-6 prophage; IS911A regulator fragment b0255,b0257,b4587