# Copies and Copyright-Notice # # RegulonDB is free for academic/noncommercial use # # User is not entitled to change or erase data sets of the RegulonDB # database or to eliminate copyright notices from RegulonDB. Furthermore, # User is not entitled to expand RegulonDB or to integrate RegulonDB partly # or as a whole into other databank systems, without prior written consent # from CCG-UNAM. # # Please check the license at http://regulondb.ccg.unam.mx/menu/download/full_version/terms_and_conditions.jsp # # Citation # # Tierrafría, V. H. et al. (2022). RegulonDB 11.0: Comprehensive high-throughput datasets on transcriptional regulation in Escherichia coli K-12, # Microb Genom. 2022 May;8(5). doi: 10.1099/mgen.0.000833. PMID: 35584008. https://doi.org/10.1099/mgen.0.000833 # # # # TF family data publication: # Gama-Castro S, Salgado H, Santos-Zavaleta A, Ledezma- Tejeida D, Muñiz-Rascado L, # García-Sotelo JS, Alquicira-Hernández K, Martínez-Flores I, Pannier L, Castro- Mondragón JA, # Medina-Rivera A, Solano-Lira H, Bonavides-Martínez C, Pérez-Rueda E, Alquicira-Hernández S, # Porrón-Sotelo L, López-Fuentes A, Hernández-Koutoucheva A, Moral-Chávez VD, Rinaldi F, # Collado-Vides J. RegulonDB version 9.0: high-level integration of gene regulation, coexpression, # motif clustering and beyond., Nucleic Acids Research,2016, Vol.44, Pag.133-143.ISSN: 0305-1048 # # TF Sensing Class data publication: # Martínez-Antonio A, Janga SC, Salgado H and Collado-Vides J. Internal-sensing machinery directs the activity of # the regulatory network in Escherichia coli. Trends Microbiol. 2006. Jan;14(1):22-7. # # TF Connectivity Class data publication: # Martínez-Antonio A, Collado-Vides J. Identifying global regulators in transcriptional regulatory networks in bacteria. # Curr Opin Microbiol. 2003 Oct;6(5):482-9 # # # Contact # # Person: RegulonDB Team # Web Page: http://regulondb.ccg.unam.mx/menu/about_regulondb/contact_us/index.jsp # (regulondb@ccg.unam.mx) # # # Release: 11.2 Date: 05/22/2023 # Genome version: U00096.3, Refseq version: NC_000913.3; GI:556503834 # ___________________________________________________________________________ # Created: 06/12/2023 13:37:29 # Columns: # (1) Transcription Factor (TF) identifier assigned by RegulonDB # (2) TF Name # (3) TF Synonyms List # (4) Gene Coding for the TF # (5) TF Active Conformations # (6) TF Inactive Conformations # (7) TF Active Conformations Synonyms List # (8) TF Inactive Conformations Synonyms List # (9) Effector Name related to TF Active Conformations # (10) Effector Name related to TF Inactive Conformations # (11) Effector Synonyms List related to TF Active Conformations TF # (12) Effector Synonyms List related to TF Inactive Conformations TF # (13) TF Symmetry # (14) TF Family # (15) TF Connectivity Class # (16) TF Sensing Class # (17) Evidence that supports the TF conformation [Evidence code | Evidence type: C = Confirmed, S = Strong, W = Weak | Evidence name ] # (18) addEvidence. Additive Evidence [CV(EvidenceCode1/EvidenceCodeN)|Confidence Level] # (19) confidenceLevel. Confidence level (Values: Confirmed, Strong, Weak) # (20) TF conformation reference identifier (PMID) ECK125328145 AaeR DNA-binding transcriptional activator AaeR,LysR-type transcriptional regulator AaeR,QseA,YhcS,quorum sensing transcriptional regulator of LYSR-type aaeR AaeR LysR-type transcriptional regulator AaeR;QseA;YhcS;quorum sensing transcriptional regulator of LYSR-type inverted-repeat Local Regulator [COMP-HINF|W],[COMP-HINF-FN-FROM-SEQ|W],[EXP-IMP|W] - Weak 10734204, 12011002, 15489430, 15556475 ECK125286586 AccB AccB,BCCP,FabE,apo-[acetyl-CoA:carbon-dioxide ligase (ADP forming)] accB AccB BCCP Local Regulator [EXP|W] - Weak 10542197, 14594796, 2575489, 2660106, 2822655, 7945216 ECK120015994 AcrR DNA-binding transcriptional repressor AcrR,YbaH acrR AcrR AcrR-Proflavin | AcrR-R6G | AcrR-ethidium YbaH R6G | Proflavin | ethidium ethidium cation;homidium inverted-repeat TetR/AcrR Local Regulator [EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 17644067, 18607081, 8821940 ECK120012595 Ada DNA-binding transcriptional dual regulator / DNA repair protein Ada ada Ada-Methylated | Ada Methyl inverted-repeat AraC/XylS Local Regulator Using internal synthesized signals [EXP-IDA|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 11284682, 15305584, 15305585, 16452614, 1995192, 2002008, 2536670, 282622, 2982792, 2987251, 29941584, 3009022, 3047400, 3141384, 3343221, 3526284, 3529081, 3889845, 7896807, 7937881, 8195077, 8676855, 8720133, 8752326, 8755711, 9383376, 9582376 ECK120014170 AdiY DNA-binding transcriptional activator AdiY adiY AdiY inverted-repeat AraC/XylS Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 8704970 ECK120012515 AgaR DNA-binding transcriptional repressor AgaR,YhaW agaR AgaR YhaW direct-repeat DeoR Local Regulator External sensing using transported metabolites [EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 14731281 ECK125134683 AidB isovaleryl-CoA dehydrogenase and DNA-binding transcriptional repressor,putative acyl-CoA dehydrogenase AidB aidB AidB-isovaleryl-CoA AidB_like Local Regulator [EXP-IEP|W],[EXP-IDA-PART-PURIFIED-PROTEIN|W] - Weak 15977811, 20889740 ECK120030264 AlaS Act,AlaS,LovB,ala-act alaS AlaS-L-alanine AlaS L-alanine L-α-alanine;ala;alanine inverted-repeat Class II aminoacyl_tRNA synthetase Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 20179335, 23536244, 24493149, 25918376, 27622773, 6264314 ECK120015630 AllR DNA-binding transcriptional repressor AllR,YbbU allR AllR-allantoin | AllR AllR-glyoxylate AllR;AllR-glyox;B0506;YbbU allantoin glyoxylate glyox;glyoxalate;glyoxylic acid inverted-repeat IclR Local Regulator External sensing using transported metabolites [EXP-IEP|W],[EXP-IDA-UNPURIFIED-PROTEIN|W] - Weak 10601204, 12460564 ECK120015636 AllS DNA-binding transcriptional activator AllS,GlxA1,YbbS allS AllS-allantoin AllS AllS;B0504;YbbS allantoin LysR Local Regulator Sensing external and internal signals [EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W] - Weak 12460564 ECK120012984 AlpA CP4-57 prophage; DNA-binding transcriptional activator AlpA alpA AlpA inverted-repeat AlpA Local Regulator [EXP-IMP|W] - Weak 7511582 ECK120011959 AlsR DNA-binding transcriptional repressor AlsR,RpiR,YjcY alsR AlsR AlsR-D-allose RpiR;YjcY AlsR;AlsR-allose;RpiR;YjcY D-allose inverted-repeat RpiR Local Regulator External sensing using transported metabolites [COMP-HINF|W],[EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 10559180, 8576032, 9401019 ECK120012987 AppY DLP12 prophage; DNA-binding transcriptional activator AppY appY AppY inverted-repeat AraC/XylS Local Regulator [EXP|W] - Weak 2537825, 27718375, 3295784, 8071219 ECK120012316 AraC DNA-binding transcriptional dual regulator AraC araC AraC-α-L-arabinopyranose | AraC AraC-D-fucose AraC-arabinose | α-L-arabinopyranose D-fucose α-L-arabinose inverted-repeat AraC/XylS Local Regulator Sensing external and internal signals [EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 2231717, 7768852, 8510144, 8516313, 8980677 ECK120011345 ArcA ArcA response regulator,CpxC,DNA-binding transcriptional dual regulator ArcA,Dye,FexA,Msp,Seg,SfrA,dye resistance protein arcA ArcA-phosphorylated ArcA ArcA;ArcA response regulator - phosphorylated;ArcA-Pasp54;CpxC;Dye;FexA;Msp;Seg;SfrA Phosphate OmpR Global Regulator External-Two-component systems [COMP-HINF-FN-FROM-SEQ|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 12486057, 1482126, 1512197, 16849788, 19715602, 2157156, 2984198, 7699720, 7855430, 7957084, 8098993, 8226939 ECK120011202 ArgP DNA-binding transcriptional dual regulator ArgP,IciA argP ArgP-L-arginine | ArgP ArgP-L-lysine ArgP-arginine | ArgP-lysine L-arginine L-lysine 2-amino-5-guanidinovaleric acid;L-arg;R;arg;arginine 2,6-diaminohexanoic acid;K;L-lys;lys;lysine;lysine acid LysR Local Regulator Using internal synthesized signals [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IPI|W] - Weak 17504942, 2034653, 8825783, 9819053 ECK120011670 ArgR DNA-binding transcriptional dual regulator ArgR,XerA argR ArgR-L-arginine ArgR ArgR-arg L-arginine 2-amino-5-guanidinovaleric acid;L-arg;R;arg;arginine ArgR Local Regulator Sensing external and internal signals [COMP-HINF-FN-FROM-SEQ|W],[EXP-IPI|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 11580241, 1640456, 1640457, 17850814, 3116542, 3149585, 4555419, 7997172, 8594204 ECK120030724 ArsR ArsE,DNA-binding transcriptional repressor ArsR arsR ArsR ArsR-antimonite | ArsR-arsenite arsenite | antimonite arsenite1-;iAsIII | ArsR Local Regulator External sensing using transported metabolites [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 12829264, 8051064, 8576202, 8764681 ECK120026318 AscG DNA-binding transcriptional repressor AscG,Sac ascG AscG Sac asymmetric, inverted-repeat GalR/LacI Local Regulator External sensing using transported metabolites [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 1630307, 19633077 ECK120013010 AsnC DNA-binding transcriptional dual regulator AsnC asnC AsnC AsnC-L-asparagine L-asparagine α-aminosuccinamic acid;(-)-asparagine;(S)-2,4-diamino-4-oxobutanoic acid;(S)-asparagine;2,4-diamino-4-oxobutanoic acid, (S)-;2-aminosuccinamic acid, L-;L-β-asparagine;L-2,4-diamino-4-oxobutanoic acid;L-asn;L-asparatamine;N;agedoite;altheine;asn;asparagine;asparagine acid;aspartic acid β-amide;butanoic acid, 2,4-diamino-4-oxo-, (S)- inverted-repeat AsnC Local Regulator Sensing external and internal signals [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W] - Weak 16528101, 2864330, 6357950, 7686882 ECK120013014 AtoC AtoC response regulator,AtoC transcriptional activator; Az protein inhibitor of ODC,DNA-binding transcriptional activator/ornithine decarboxylase inhibitor AtoC atoC AtoC-phosphorylated AtoC AtoC response regulator - phosphorylated;AtoC-P;AtoC-Pasp55 Phosphate EBP Local Regulator External-Two-component systems [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 1482126, 2157156, 2883171, 7699720, 8098993, 8346225 ECK120015687 BaeR BaeR response regulator,DNA-binding transcriptional activator BaeR baeR BaeR-phosphorylated BaeR BaeR response regulator - phosphorylated;BaeR-Pasp61 Phosphate inverted-repeat OmpR Local Regulator External-Two-component systems [EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 12107134, 1482126, 2157156, 32094588, 7699720, 8098993 ECK125145855 BasR BasR response regulator,DNA-binding transcriptional dual regulator BasR,PmrA basR BasR-phosphorylated BasR BasR;BasR response regulator - phosphorylated;BasR-Pasp51;PmrA Phosphate inverted-repeat OmpR Local Regulator External-Two-component systems [EXP-IDA|W],[COMP-AINF-FN-FROM-SEQ|W] - Weak 10373459, 11222580, 1482126, 15522865, 15556475, 15569938, 15659161, 17686460, 2157156, 7565089, 7699720, 8098993 ECK120013017 BetI DNA-binding transcriptional repressor BetI betI BetI BetI-choline B0313;BetI choline (2-hydroxyethyl)trimethylammonium inverted-repeat TetR/AcrR Local Regulator External sensing using transported metabolites [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 1956285, 8626295 ECK120012646 BirA BioR,DNA-binding transcriptional repressor/biotin-[acetyl-CoA-carboxylase] ligase BirA,DhbB,biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor birA BirA-biotinyl-5'-adenylate BirA BioR;BirA;BirA-bio-5'-AMP;DhbB biotinyl-5'-adenylate biotinyl-5'-AMP BirA Local Regulator Using internal synthesized signals [COMP-HINF-FN-FROM-SEQ|W],[EXP-IPI|W] - Weak 1097077, 11106165, 30904393, 3325774, 350835, 3536662, 366433, 3899863, 6456358, 7024555, 7945216, 9750231 ECK120051438 BluR DNA-binding transcriptional repressor BluR,YcgE bluR BluR YcgE inverted-repeat MerR Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 15556475, 19240136 ECK120029348 BolA DNA-binding transcriptional dual regulator BolA bolA BolA-phosphorylated BolA-phosphate Phosphate inverted-repeat BolA Local Regulator External-Two-component systems [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IPI|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 12354237, 2684651, 3053647, 32535996 ECK125145850 BtsR DNA-binding transcriptional dual regulator BtsR,YehT btsR BtsR-Phosphorylated BtsR YehT-P Phosphate LytTR Local Regulator External-Two-component systems [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[COMP-HINF-ISA|W],[EXP-IMP|W],[EXP-IPI|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 12618449, 12951338, 22685278, 31834370 ECK120011235 CRP Cap,Csm,DNA-binding transcriptional dual regulator CRP,GurB crp CRP-cyclic-AMP CRP CRP-cAMP cyclic-AMP 3',5'-cyclic AMP;adenosine 3',5'-cyclic phosphate;adenosine cyclic-3',5'-monophosphate;adenosine cyclic-monophosphate;adenosine-3',5'-cyclic monophosphate;adenosine-3',5'-monophosphate;adenosine-cyclic-phosphate;adenosine-cyclic-phosphoric-acid;cAMP;cyclic 3',5'-AMP;cyclic-3',5'-adenosine monophosphate inverted-repeat CRP Global Regulator Using internal synthesized signals [COMP-HINF|W],[COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W],[EXP-IPI|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W],[EXP-IDA-PART-PURIFIED-PROTEIN|W] - Weak 10564497, 10760178, 10852886, 11742992, 12923087, 1328816, 14638413, 15150239, 15520470, 15659676, 16166533, 19439203, 31543875, 7551052, 8604346, 8735277 ECK125286587 CRP-Sxy DNA-binding transcriptional repressor CRP-Sxy crp, sxy CRP-Sxy Local Regulator [EXP-IMP|W] - Weak 31543875 ECK120011250 CadC DNA-binding transcriptional activator CadC cadC CadC inverted-repeat OmpR Local Regulator External sensing using transported metabolites [EXP-IMP|W] - Weak 1370290, 18086202, 7830562 ECK120013805 CaiF DNA-binding transcriptional activator CaiF caiF CaiF-L-carnitine CaiF L-carnitine γ-L-trimethyl-β-hydroxybutyrobetaine;γ-trimethyl-hydroxybutyrobetaine;(3R)-3-hydroxy-4-(trimethylammino)butanoate;(R)-carnitine;3-carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium;bicarnesine;vitamin B T;vitamin Bt CaiF Local Regulator External sensing using transported metabolites [EXP-IDA-PURIFIED-PROTEIN|W] - Weak 10564497, 8631699, 9573142 ECK120013750 Cbl DNA-binding transcriptional activator Cbl cbl Cbl Cbl-Thiosulphate | Cbl-adenosine 5'-phosphosulfate B1987;Cbl;Cbl-APS adenosine 5'-phosphosulfate | Thiosulphate APS;adenosine 5'-sulphatophosphate;adenosine phosphosulfate;adenylyl-sulfate | inverted-repeat LysR Local Regulator Using internal synthesized signals [EXP|W] - Weak ECK120011953 CdaR DNA-binding transcriptional activator CdaR,SdaR,YaeG cdaR CdaR SdaR;YaeG inverted-repeat Cdar Local Regulator Using internal synthesized signals [EXP-IGI-FUNC-COMPLEMENTATION|S],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Strong 10762278, 14645248 ECK125230705 CecR DNA-binding transcriptional dual regulator CecR,YbiH cecR CecR YbiH inverted-repeat TetR/AcrR Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IDA-UNPURIFIED-PROTEIN-NH|W],[EXP-IEP|W],[EXP-IPI|W] - Weak 10734204, 15556475, 27112147, 30137486, 30578262 ECK120012036 ChbR CelD chbR ChbR-6-phospho-β-D-glucosaminyl-(1->4)--acetyl-D-glucosamine | ChbR ChbR-N-monoacetylchitobiose 6'-phosphate | 6-phospho-β-D-glucosaminyl-(1->4)-N-acetyl-D-glucosamine N-monoacetylchitobiose 6-phosphate;GlcN6P-GlcNAc asymmetric AraC/XylS Local Regulator External sensing using transported metabolites [EXP-IDA|W] - Weak 15066032, 2179047, 22797760 ECK125141239 ComR DNA-binding transcriptional repressor ComR,YcfQ comR ComR ComR-Cu YcfQ ComR-Cu(I) Cu+ CuI;copper(I);cuprous copper;cuprous ion inverted-repeat TetR/AcrR Local Regulator [EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 15556475, 22089859 ECK120011210 CpxR CpxR response regulator,DNA-binding transcriptional dual regulator CpxR,YiiA cpxR CpxR-phosphorylated CpxR CpxR response regulator - phosphorylated;CpxR-Pasp51;CpxR-Pasp Phosphate OmpR Local Regulator External-Two-component systems [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IPI|W] - Weak 1482126, 15686558, 16077119, 16487683, 2157156, 7699720, 7883164, 8098993, 8294007, 9159398 ECK120013112 Cra DNA-binding transcriptional dual regulator Cra,FruC,FruR,Shl cra Cra Cra-beta;-D-fructose 1,6-bisphosphate | Cra-β-D-fructofuranose 1-phosphate FruR Cra-fructose-1-phosphate;FruR-fructose-1-phosphate β-D-fructofuranose 1-phosphate β-D-fructofuranose-1-P inverted-repeat GalR/LacI Local Regulator Using internal synthesized signals [COMP-HINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 1630901, 1851954, 2198273, 8195118, 8230205, 8858581, 9237914, 9371462 ECK120035002 CreB CreB response regulator,DNA-binding transcriptional regulator CreB,YjjE creB CreB-phosphorylated CreB CreB response regulator - phosphorylated;CreB-Pasp54;YjjE Phosphate OmpR Local Regulator External-Two-component systems [EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 11350954, 1482126, 18375564, 2157156, 7699720, 7855419, 8098993 ECK120013342 CsgD DNA-binding transcriptional dual regulator CsgD csgD CsgD asymmetric LuxR/UhpA Local Regulator [EXP|W] - Weak ECK120013061 CspA CS7.4,DNA-binding transcriptional activator CspA,F10.6,cold shock protein CspA,major cold shock protein 7.4 cspA CspA CS7.4;DNA-binding transcriptional activator CspA;F10.6;major cold shock protein 7.4 asymmetric Cold Local Regulator [EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 19486664, 1961761, 28334975, 32753505, 3553157, 8995247 ECK125285349 CsqR DNA-binding transcriptional dual regulator CsqR,YihW csqR CsqR CsqR-6-sulfo-D-quinovose YihW YihW-6-sulfo-D-quinovose 6-sulfo-D-quinovose 6-deoxy-6-sulfo-D-glucopyranose;6-deoxy-6-sulfoglucose;sulfoquinovose;sulphoquinovose inverted-repeat Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 10734204, 15556475, 29453395, 30372406 ECK125288994 CueR CopR,DNA-binding transcriptional dual regulator CueR,YbbI cueR CueR-Cu | CueR-Ag | CueR-Au Au | Cu+ | Ag CuI;copper(I);cuprous copper;cuprous ion | inverted-repeat Local Regulator External sensing using transported metabolites [EXP-IGI-FUNC-COMPLEMENTATION|S],[EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IPI|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Strong 10915804, 11136469, 11167016, 12446701, 12958362, 14518983, 15773991 ECK120011941 CusR CusR response regulator,DNA-binding transcriptional activator CusR,YlcA cusR CusR-phosphorylated CusR AgrR;CusR;CusR response regulator - phosphorylated;CusR-Pasp51;CusR-Pasp;CusR-Pasp;YlcA Phosphate OmpR Local Regulator External-Two-component systems [EXP|W],[COMP-HINF-FN-FROM-SEQ|W],[EXP-IMP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 11004187, 11514505, 15522865, 15773991, 30530842 ECK120013065 CynR DNA-binding transcriptional dual regulator CynR cynR CynR | CynR-cyanate B0338;CynR cyanate cyanic acid;hydrogen cyanate inverted-repeat LysR Local Regulator External sensing using transported metabolites [EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IPI|W] - Weak 1592818, 7961413, 8253686 ECK120011312 CysB DNA-binding transcriptional dual regulator CysB,positive transcriptional regulator for cysteine regulon cysB CysB-N-acetyl-L-serine | CysB | CysB--acetyl-L-serine CysB-Sulphide | CysB-Thiosulfate O-acetyl-L-serine | N-acetyl-L-serine Sulphide | Thiosulphate (2S)-3-acetyloxy-2-aminopropanoate;O-acetylserine;O3-acetyl-L-serine;acetylserine | LysR Local Regulator Sensing external and internal signals [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W],[EXP-IDA-PART-PURIFIED-PROTEIN|W] - Weak 1435253, 14663078, 15255893, 1541275, 2182030, 27718375, 3032952, 3094306, 6792186, 9401024 ECK120012407 CytR DNA-binding transcriptional repressor CytR cytR CytR CytR-cytidine cytidine inverted-repeat GalR/LacI Local Regulator Sensing external and internal signals [EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IPI|W] - Weak 1328649, 1655726, 2162050, 2162467, 3515317, 8346018 ECK120051451 Dan DNA-binding transcriptional activator Dan,TtdR,YgiP ttdR Dan-L-tartrate Dan L-tartrate (+)-tartrate;(2R,3R)-tartaric acid;(2R,3R)-tartrate;(R,R)-tartrate;L(+)-tartaric acid;L-tartarate;L-tartaric acid;L-threarate;tartaric acid;tartrate;weinsaeure LysR Local Regulator [EXP-IDA|W],[COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IDA-PART-PURIFIED-PROTEIN-NH|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 10734204, 15556475, 19661178, 20156994 ECK125286588 DcuR DNA-binding transcriptional activator DcuR,DcuR response regulator,YjdG dcuR DcuR-phosphorylated DcuR DcuR response regulator - phosphorylated;DcuR-P;DcuR-Pasp56;DcuR-Pasp Phosphate inverted-repeat OmpR Local Regulator External-Two-component systems [EXP-IGI-FUNC-COMPLEMENTATION|S],[EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IPI|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Strong 15073297, 9765574, 9973351 ECK125235978 DecR CyuR,DNA-binding transcriptional activator DecR,YbaO decR DecR CyuR;YbaO inverted-repeat AsnC Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IDA-PART-PURIFIED-PROTEIN-NH|W],[EXP-IPI|W] - Weak 10734204, 10850996, 15556475, 27435271, 30137486 ECK120012664 DeoR DNA-binding transcriptional repressor DeoR,NucR,transcriptional repressor for deo operon, tsx, nupG deoR DeoR DeoR-Deoxyribose-5-phosphate NucR;transcriptional repressor for deo operon, tsx, nupG Deoxyribose-5-phosphate inverted-repeat DeoR Local Regulator Using internal synthesized signals [EXP|W] - Weak 2653814, 2994018 ECK125285348 DgoR DNA-binding transcriptional regulator DgoR,YidW dgoR DgoR DgoR-D-galactonate D-galactonate galactonate inverted-repeat Local Regulator [EXP-IDA|W],[COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IDA-PART-PURIFIED-PROTEIN-NH|W],[EXP-IPI|W] - Weak 11756427, 15556475, 29728462, 30455279, 33068046 ECK120015690 DhaR DNA-binding transcriptional dual regulator DhaR,YcgU dhaR DhaR DhaR-DhaK YcgU DhaK inverted-repeat EBP Local Regulator [EXP-IMP|W] - Weak 15616579 ECK120029345 DicA DNA-binding transcriptional dual regulator DicA,FtsT dicA DicA FtsT inverted-repeat HTH_3 Local Regulator [EXP-IGI-FUNC-COMPLEMENTATION|S],[COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 23028867, 3041373, 3053647 ECK125257188 DinJ-YafQ DinJ-YafQ antitoxin/toxin complex / DNA-binding transcriptional repressor,DinJ/Q dinJ, yafQ DinJ-YafQ DinJ/Q inverted-repeat Local Regulator [EXP-IDA|W],[EXP-IGI|W] - Weak 17263853, 19210620 ECK120011903 DnaA chromosomal replication initiator protein DnaA,chromosomal replication initiator protein/DNA-binding transcriptional dual regulator DnaA dnaA DnaA-ATP DnaA B3702;DnaA ATP adenosine-5'-triphosphate;adenosine-triphosphate;adenylpyrophosphate DnaA Local Regulator Using internal synthesized signals [EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IPI|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 10497067, 11160809, 160412, 20487274, 2540187, 27484197, 33382157, 337131, 6296774, 6310593, 6327277, 8825783, 9125116 ECK120034476 DpiA CitB,CriR,DNA-binding transcriptional dual regulator DpiA,DpiA response regulator,MpdA dpiA DpiA-phosphorylated DpiA CitB response regulator - phosphorylated;CriR;DpiA response regulator - phosphorylated;DpiA-Pasp57;DpiA-Pasp;MpdA Phosphate inverted-repeat HTH_11 Local Regulator External-Two-component systems [IDA-PURIFIED-PROTEIN-NH|S] - Strong 18997424 ECK120013081 DsdC DNA-binding transcriptional dual regulator DsdC dsdC DsdC-D-serine DsdC D-serine inverted-repeat LysR Local Regulator Sensing external and internal signals [EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W] - Weak 3275618, 6296057, 7592420 ECK120013085 EbgR DNA-binding transcriptional repressor EbgR ebgR EbgR inverted-repeat GalR/LacI Local Regulator [EXP|W] - Weak ECK120035026 EnvR AcrS,DNA-binding transcriptional repressor EnvR,YhdK envR EnvR AcrS;YhdK inverted-repeat TetR/AcrR Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 18567659, 7592375, 8196548 ECK120011792 EnvY DNA-binding transcriptional activator EnvY,envelope protein; thermoregulation of porin biosynthesis envY EnvY envelope protein; thermoregulation of porin biosynthesis inverted-repeat AraC/XylS Local Regulator [EXP|W] - Weak 2536924 ECK120011575 EvgA DNA-binding transcriptional activator EvgA,EvgA response regulator evgA EvgA-phosphorylated EvgA EvgA response regulator - phosphorylated;EvgA-Pasp Phosphate LuxR/UhpA Local Regulator External-Two-component systems [EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W],[EXP-IGI|W] - Weak 10923791, 11157960, 11914367, 12135487, 12399493, 12670992, 14523115, 15126461, 15489450 ECK120012141 ExuR DNA-binding transcriptional repressor ExuR,negative regulator of exu regulon, exuT, uxaAC, and uxuB exuR ExuR-α-D-galacturonate, α-D-glucuronate | ExuR ExuR-α-D-glucuronate negative regulator of exu regulon, exuT, uxaAC, and uxuB α-D-galacturonate α-D-glucuronate α-D-galacturonic acid α-D-glucopyranuronic acid;α-D-glucuronic acid inverted-repeat GntR Local Regulator External sensing using transported metabolites [EXP|W] - Weak 6357945 ECK120011229 FNR DNA-binding transcriptional dual regulator FNR,NirA,NirR,OssA,OxrA fnr FNR | FNR-[4Fe-4S] reduced FNR-[2Fe-2S] oxidized [4Fe-4S]2+ reduced [2Fe-2S]2+ oxidized inverted-repeat CRP Global Regulator Using internal synthesized signals [COMP-HINF-FN-FROM-SEQ|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-PART-PURIFIED-PROTEIN-NH|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 11407111, 11771123, 11931557, 17293415, 1854188, 1957353, 2181237, 2248796, 2677602, 6292868, 7747934, 796407, 8119409, 8412675, 8588737, 8871401, 9230919, 9282732, 9990723 ECK120011354 FabR DNA-binding transcriptional repressor FabR,YijC fabR FabR YijC inverted-repeat TetR/AcrR Local Regulator [EXP-IDA|W],[EXP-IEP|W],[EXP-IPI|W] - Weak 11160901, 11859088 ECK120011824 FadR DNA-binding transcriptional dual regulator FadR,Dec,Ole,OleR,ThdB fadR FadR FadR-an acyl-CoA Dec;Ole;OleR;ThdB B1187;Dec;FadR;FadR-acyl-CoA;Ole;OleR;ThdB an acyl-CoA RCH2CH2CO-CoA;acyl-Coenzyme A;acyln+2-CoA;acyln-2-CoA;fatty acyl thioester-CoA inverted-repeat GntR Local Regulator Using internal synthesized signals [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 10592242, 11566998, 1569108, 2843809, 8446033, 9767562 ECK120026337 FeaR DNA-binding transcriptional activator FeaR,MaoB,MaoX,YdbM feaR FeaR MaoB;MaoX;YdbM inverted-repeat AraC/XylS Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 8631685, 9043126 ECK120011394 FhlA DNA-binding transcriptional activator FhlA,Fhl,formate hydrogen-lyase transcriptional activator for fdhF, hyc and hyp operons fhlA FhlA-formate FhlA B2731;Fhl;FhlA formate formic acid inverted-repeat EBP Local Regulator Using internal synthesized signals [EXP-IGI-FUNC-COMPLEMENTATION|S],[EXP-IDA-PURIFIED-PROTEIN|W] - Strong 2118503, 2280686, 8034727 ECK120011186 Fis DNA-binding transcriptional dual regulator Fis,Nbp,site-specific DNA inversion stimulation factor fis Fis inverted-repeat EBP Global Regulator TFs for DNA-bending [EXP-IDA|W],[EXP-IEP|W],[EXP-IPI|W] - Weak 1484481, 1547773, 27718375, 7545153 ECK125257194 FlhDC FlhDC DNA-binding transcriptional dual regulator flhC, flhD FlhDC asymmetric Local Regulator [EXP-IDA-PURIFIED-PROTEIN|W] - Weak 12144778, 7961507 ECK125141939 FliZ DNA-binding transcriptional regulator FliZ,YedH fliZ FliZ YedH inverted-repeat Local Regulator [EXP-IMP|W] - Weak 18765794 ECK125302601 FrlR DNA-binding transcriptional regulator FrlR,YhfR frlR FrlR FrlR--phospho-D-fructos-1-yl)-L-lysine N6-(1-deoxy-6-O-phospho-D-fructos-1-yl)-L-lysine fructoselysine 6-phosphate;fructoselysine-6-P Local Regulator [COMP-HINF-ORTHOLOGY-EXP|W],[COMP-HINF-FN-FROM-SEQ|W],[EXP-IMP|W] - Weak 10734204, 15556475, 32979851 ECK125257185 FrmR DNA-binding transcriptional repressor FrmR,YaiN frmR FrmR FrmR-formaldehyde FrmR-formol formaldehyde formalin;formol;methanal Local Regulator [COMP-HINF|W],[EXP-IEP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 15466022, 27983483 ECK120013118 FucR DNA-binding transcriptional activator FucR fucR FucR-L-fuculose-1-P FucR L-fuculose 1-phosphate L-fuculose-1-P DeoR Local Regulator External sensing using transported metabolites [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W] - Weak 2664711, 3005235, 3325779, 8955387 ECK125285350 Fur DNA-binding transcriptional dual regulator Fur fur Fur-Fe Fur Fe2+ | Mn2+ FeII;ferrous ion;ferrous iron;iron(II) | Mn(II) (incorrect);Mn++;MnII;manganese(II) inverted-repeat Local Regulator External sensing using transported metabolites - - 1868094, 2015825, 2823881, 2993806, 7026976 ECK120012092 GadE DNA-binding transcriptional activator GadE,YhiE,YhiT,acid-responsive regulator of gadA and gadBC gadE GadE YhiE;YhiT;acid-responsive regulator of gadA and gadBC asymmetric LuxR/UhpA Local Regulator [EXP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 12399493, 12426343, 12657056, 12694615, 12704134, 12940989, 14702398, 20189963, 30578262, 32094588 ECK125257204 GadE-RcsB GadE-RcsB DNA-binding transcriptional activator,GadRcs gadE, rcsB GadE-RcsB GadRcs asymmetric Local Regulator [IDA-PURIFIED-PROTEIN-NH|S] - Strong 20189963 ECK120011465 GadW DNA-binding transcriptional dual regulator GadW,YhiW gadW GadW YhiW asymmetric AraC/XylS Local Regulator [EXP|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 12446650 ECK120011458 GadX DNA-binding transcriptional dual regulator GadX,YhiX gadX GadX YhiX asymmetric AraC/XylS Local Regulator [EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 11976288, 12446650 ECK120012713 GalR DNA-binding transcriptional dual regulator GalR galR GalR-D-galactose | GalR B2837;GalR;GalR-galactose | D-galactose D-Gal inverted-repeat GalR/LacI Local Regulator Sensing external and internal signals [EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IPI|W],[EXP-IMP|W] - Weak 12169637, 15533432, 15807530, 17630975, 6283521, 6350601, 7934815, 8188660, 9218807, 9325090 ECK120012704 GalS DNA-binding transcriptional dual regulator GalS,MglD galS GalS | GalS-D-galactose MglD | B2151;GalS;GalS-galactose;MglD D-galactose D-Gal inverted-repeat GalR/LacI Local Regulator Sensing external and internal signals [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W],[EXP-IPI|W],[EXP-IGI|W] - Weak 1619663, 1900742, 7934815, 8416900, 8982002 ECK120013131 GatR gatR GatR inverted-repeat Local Regulator External sensing using transported metabolites - - 1661252, 7772602 ECK120012465 GcvA DNA-binding transcriptional dual regulator GcvA,positive regulator of gcv operon gcvA GcvA GcvA-Purine | GcvA-glycine positive regulator of gcv operon GcvA-gly glycine | Purine G;aminoacetic acid;gly | inverted-repeat LysR Local Regulator Sensing external and internal signals [COMP-HINF-FN-FROM-SEQ|W],[EXP-IDA-BINDING-OF-PURIFIED-PROTEINS|S],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Strong 27718375, 7665470, 8188587, 8375392 ECK120012075 GlaR CsiR,DNA-binding transcriptional repressor GlaR,GabC,YgaE glaR GlaR GlaR-glutarate CsiR;GabC;YgaE glutarate glutaric acid;pentanedioate inverted-repeat GntR Local Regulator [EXP-IMP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 12446648, 2188954, 24037, 28061857, 30498244 ECK120011437 GlcC DNA-binding transcriptional dual regulator GlcC,YghN glcC GlcC-glycolate | GlcC-Acetate GlcC B2980;GlcC;YghN | glycolate | Acetate glycolic acid;glycollate;hydroxyacetic acid | inverted-repeat GntR Local Regulator Sensing external and internal signals [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IDA-PART-PURIFIED-PROTEIN-NH|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 8606183, 9880556 ECK120012730 GlpR glpR GlpR GlpR--glycerol 3-phosphate | GlpR-glycerol B3423;GlpR;GlpR-glycerol-3-phosphate | sn-glycerol 3-phosphate | glycerol α-glycerophosphate;α-glycerophosphoric acid;D-glycerol 1-phosphate;L-α-glycerophosphate;L-G3P;L-glycerol 3-phosphate;glycerol 3-phosphate | 1,2,3-trihydroxypropane;1,2,3-trihydroxypropanol;glycerin inverted-repeat DeoR Local Regulator Sensing external and internal signals [EXP|W] - Weak 1556120, 3316209, 8955387 ECK125108627 GlrR DNA-binding transcriptional activator GlrR,GlrR response regulator,QseF,YfhA glrR GlrR-phosphorylated GlrR GlrR;GlrR response regulator - phosphorylated;GlrR-Pasp56;YfhA Phosphate EBP Local Regulator External-Two-component systems [COMP-HINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W] - Weak 10734204, 15522865, 15556475, 19843219 ECK120012096 GntR DNA-binding transcriptional repressor GntR gntR GntR GntR-D-gluconate B3438;GntR;GntR-gluconate D-gluconate D-gluconic acid;dextronic acid;maltonic acid inverted-repeat GalR/LacI Local Regulator Sensing external and internal signals [EXP|W] - Weak 4574690, 8655507 ECK120013141 GutM DNA-binding transcriptional activator GutM,Gut,SrlM gutM GutM Gut;SrlM inverted-repeat GutM Local Regulator External sensing using transported metabolites [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W] - Weak 3062173 ECK120011294 H-NS BglY,Cur,DNA-binding protein HLP-II (HU, BH2, HD, NS),DNA-binding transcriptional dual regulator H-NS,Drc,DrdX,Drs,FimG,Hns,HnsA,Irk,MsyA,OsmZ,PilG,TopS,TopX,VirR hns H-NS BglY;Cur;DNA-binding protein HLP-II (HU, BH2, HD, NS);Drc;DrdX;Drs;FimG;Hns;HnsA;Irk;MsyA;OsmZ;PilG;TopS;TopX;VirR inverted-repeat HNS Global Regulator TFs for DNA-bending [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IPI|W],[EXP-IMP|W] - Weak 11278074, 15100692, 1537791, 15795232, 15853876, 16384714, 16879983, 1691451, 16980475, 17116239, 17553830, 17827501, 17881364, 2020545, 2126011, 2177526, 2841565, 3135462, 6370250, 7748941, 7934818, 8437561, 8890170, 9513262, 9987132 ECK125257184 HU DNA-binding transcriptional dual regulator HU,HUαβ hupA, hupB HU HUαβ inverted-repeat Local Regulator TFs for DNA-bending [COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 10982882, 11254141, 11601842, 12372591, 227733, 350619, 3514923, 6987059, 9192630, 9218807 ECK120015243 HcaR DNA-binding transcriptional dual regulator HcaR,PhdR,YfhT hcaR HcaR | HcaR-3-phenylpropanoate PhdR;YfhT | B2537;HcaR;HcaR-HCA;PhdR;YfhT 3-phenylpropanoate 3-phenylpropionate;3-phenylpropionic acid;HCA;hydrocinnamate;hydrocinnamic acid;phenylpropanoate inverted-repeat LysR Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W] - Weak 11200225, 15808934, 9603882 ECK120012250 HdfR DNA-binding transcriptional dual regulator HdfR,YifA,YifD hdfR HdfR YifA;YifD inverted-repeat LysR Local Regulator [EXP-IDA-PART-PURIFIED-PROTEIN-NH|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 10913108, 21034467, 28484043 ECK125286590 HicB YdcQ,antitoxin of the HicA-HicB toxin-antitoxin system / DNA-binding transcriptional repressor HicB hicB HicB YdcQ inverted-repeat HTH_3 Local Regulator [COMP-AINF-FN-FROM-SEQ|W],[EXP-IMP|W],[EXP-IGI|W] - Weak 15556475, 17172327, 19060138 ECK125242732 HigA HigA antitoxin of the HigB-HigA toxin-antitoxin system,YgjM,antitoxin/DNA-binding transcriptional repressor HigA higA HigA HigA antitoxin of the HigB-HigA toxin-antitoxin system and DNA-binding transcriptional repressor SinR Local Regulator [COMP-HINF|W],[EXP-IMP|W],[EXP-IGI|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 19943910, 27601326, 34070637 ECK125257189 HigB-HigA HigB-HigA toxin/antitoxin complex and DNA-binding transcriptional repressor,HigBA higA, higB HigB-HigA HigBA inverted-repeat Local Regulator [COMP-HINF|W],[EXP-IMP|W] - Weak 19943910, 27601326 ECK125257201 HipAB HipAB toxin/antitoxin complex / DNA-binding transcriptional repressor,HipBA hipA, hipB HipAB HipBA inverted-repeat Local Regulator [EXP-IDA-PURIFIED-PROTEIN|W] - Weak 24089363, 8021189 ECK120026325 HipB antitoxin/DNA-binding transcriptional repressor HipB hipB HipB inverted-repeat HTH_3 Local Regulator [EXP-IGI-FUNC-COMPLEMENTATION|S],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W] - Strong 10844683, 24089363, 34070637, 8021189 ECK125228798 HprR DNA-binding transcriptional dual regulator HprR,YedW hprR HprR-phosphorylated HprR HprR-P;Modified YedW DNA-binding response regulator in two-component system with YedV;YedW-P Phosphate OmpR Local Regulator External-Two-component systems [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[COMP-HINF-ISM|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 10734204, 15556475, 25568260 ECK120011390 HyfR DNA-binding transcriptional activator HyfR hyfR HyfR inverted-repeat EBP Local Regulator [EXP|W] - Weak 9387241 ECK125141903 HypT DNA-binding transcriptional dual regulator HypT,QseD,YjiE hypT HypT-Met-oxidized HypT-[Met-oxidized];YjiE Met-oxidized LysR Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 10734204, 15556475, 20494990, 22223481, 23690622 ECK125257183 IHF DNA-binding transcriptional dual regulator IHF ihfA, ihfB IHF inverted-repeat Global Regulator TFs for DNA-bending [EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 7629095, 7651128, 7715442, 7862094, 8156991, 8230206, 8515442 ECK120011897 IclR DNA-binding transcriptional repressor IclR iclR IclR-pyruvate IclR-glyoxylate | IclR IclR-glyox | pyruvate glyoxylate α-ketopropionic acid;2-oxo-propionic acid;2-oxopropanoate;2-oxopropanoic acid;BTS;acetylformic acid;alpha-ketopropionic acid;pyroracemic acid;pyruvic acid glyox;glyoxalate;glyoxylic acid IclR Local Regulator Using internal synthesized signals [EXP-IGI-FUNC-COMPLEMENTATION|S],[COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IPI|W] - Strong 12492863, 1447784, 1995429, 1995431, 2001680, 2185227, 8265357, 8550439 ECK120012101 IdnR DNA-binding transcriptional dual regulator IdnR,GntH,YjgS idnR IdnR-Idonate | IdnR-5-dehydro-D-gluconate IdnR B4264;GntH;IdnR;IdnR-5-ketogluconate;YjgS GntH;YjgS 5-dehydro-D-gluconate | Idonate 5-dehydrogluconate;5-keto-D-gluconate;5-keto-D-gluconic acid;5-ketogluconate | inverted-repeat GalR/LacI Local Regulator Sensing external and internal signals [EXP-IEP|W] - Weak 11441462, 14973046 ECK120012965 IlvY DNA-binding transcriptional dual regulator IlvY,positive regulator for ilvC ilvY IlvY | IlvY-()-2-acetolactate | IlvY-Alfa-acetohydroxybutirate positive regulator for ilvC | IlvY-2-acetolactate | Alfa-acetohydroxybutirate | (S)-2-acetolactate α-acetolactate;(2S)-2-hydroxy-2-methyl-3-oxobutanoate;(S)-2-hydroxy-2-methyl-3-oxobutanoate inverted-repeat LysR Local Regulator Using internal synthesized signals [COMP-AINF-FN-FROM-SEQ|W],[EXP-IPI|W] - Weak 113381, 1379743, 3003115, 3062177, 3413113 ECK120011429 IscR DNA-binding transcriptional dual regulator IscR,YfhP iscR IscR-a [2Fe-2S] iron-sulfur cluster | IscR IscR-2Fe-2S | YfhP a [2Fe-2S] iron-sulfur cluster 2Fe-2S;Fe2S2;Fe2S2 iron-sulfur cluster;[2Fe-2S];[2Fe-2S] cluster;a 2Fe-2S center;a 2Fe-2S cluster;an Fe2S2 iron-sulfur center;an iron-sulfur center (ambiguous) inverted-repeat Rrf2 Local Regulator [EXP-IEP|W],[EXP-IMP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 11742080, 23075318 ECK120015250 KdgR DNA-binding transcriptional repressor KdgR,YebP kdgR KdgR YebP inverted-repeat IclR Local Regulator [EXP-IEP|W],[EXP-IMP|W] - Weak 11566977, 15659677, 4359651 ECK125286591 KdpE DNA-binding transcriptional activator KdpE,KdpE response regulator,KdpE transcriptional activator kdpE KdpE-phosphorylated KdpE KdpE response regulator - phosphorylated;KdpE-Pasp52;KdpE-Pasp Phosphate inverted-repeat OmpR Local Regulator External-Two-component systems [COMP-HINF-FN-FROM-SEQ|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W] - Weak 12115059, 1482126, 1532388, 1630316, 2157156, 7699720, 8098993 ECK120012762 LacI DNA-binding transcriptional repressor LacI,transcriptional repressor of the lac operon lacI LacI LacI-allolactose transcriptional repressor of the lac operon B0345;LacI allolactose β-D-galactopyranosyl-(1→6)-D-glucopyranose inverted-repeat GalR/LacI Local Regulator Using internal synthesized signals [EXP|W] - Weak 1107032, 13718526, 14430363, 2040302, 2178920, 2742823, 3064080, 3286877, 355891, 4571224, 4594037, 8046748 ECK120013164 LeuO DNA-binding transcriptional dual regulator LeuO leuO LeuO inverted-repeat LysR Local Regulator Using internal synthesized signals [EXP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 11121424, 15582999, 16207917, 1630901, 3413113, 3519576, 7836317, 9422614 ECK120012770 LexA DNA-binding transcriptional repressor LexA,ExrA,Spr,Tsl,UmuA lexA LexA inverted-repeat LexA Local Regulator Using internal synthesized signals [EXP-IMP-SITE-MUTATION|S],[EXP-IDA-PURIFIED-PROTEIN|W] - Strong 160562, 2780544, 6261224, 6272195, 7013987, 7027255, 7027256, 8076591, 8265357 ECK120013830 LldR DNA-binding transcriptional dual regulator LldR,Lct,LctR lldR LldR | LldR-()-lactate Lct;LctR | LldR-L-lactate (S)-lactate (S)-lactic acid;L(+)-lactate;L-lactate;L-lactic acid inverted-repeat GntR Local Regulator Sensing external and internal signals [EXP-IDA|W] - Weak 18263722 ECK120011328 LrhA DNA-binding transcriptional dual regulator LrhA,GenR lrhA LrhA GenR inverted-repeat LysR Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 12123461, 7565112, 9882671 ECK120011383 Lrp AlsB,DNA-binding transcriptional dual regulator Lrp,Ihb,LivR,Lrs,Lss,LstR,Mbf,OppI,RblA lrp Lrp | Lrp-L-leucine AlsB;Ihb;LivR;Lrs;Lss;LstR;Mbf;OppI;RblA | AlsB;B0889;Ihb;LivR;Lrp;Lrp-leu;Lrp-leucine;Lrs;Lss;LstR;Mbf;OppI;RblA L-leucine (2S)-α-2-amino-4-methylvaleric acid;(2S)-α-leucine;2-amino-4-methylvaleric acid;L;L-leu;leu;leucine inverted-repeat AsnC Global Regulator Sensing external and internal signals [COMP-HINF-FN-FROM-SEQ|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 12675791, 1346534, 1729203, 2040596, 7665463, 7901196, 8636076 ECK120015681 LsrR DNA-binding transcriptional repressor LsrR,YdeW lsrR LsrR LsrR-(2)-2-hydroxy-3,4-dioxopentyl phosphate | LsrR-autoinducer 2 | LsrR-(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran LsrR-P-DPD | LsrR-DHPD | LsrR-AI-2 (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran | autoinducer 2 | (2S)-2-hydroxy-3,4-dioxopentyl phosphate (R)-THMF;AI-2 (salmonella);autoinducer 2 (salmonella) | (4S)-4,5-dihydroxy-2,3-pentanedione;(4S)-4,5-dihydroxypentane-2,3-dione;AI-2 | (4S)-4-hydroxy-2,3-pentanedione 5-phosphate;(4S)-4-hydroxy-5-phosphooxypentane-2,3-dione inverted-repeat Sugar_binding domain Local Regulator [EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IPI|W] - Weak 15743955, 19636340, 23589368 ECK120013175 LysR DNA-binding transcriptional dual regulator LysR,positive regulator for lys lysR LysR positive regulator for lys inverted-repeat LysR Local Regulator Sensing external and internal signals [EXP|W] - Weak 6350602 ECK120013406 MalI DNA-binding transcriptional repressor MalI malI MalI inverted-repeat GalR/LacI Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[COMP|W] - Weak 1856179, 2670898 ECK120012218 MalT DNA-binding transcriptional activator MalT,MalA malT MalT-maltotriose-ADP | MalT-maltotriose-ATP MalT | MalT-Aes | MalT-MalK | MalT-MalY B3418;MalA;MalT maltotriose | maltotriose | ADP | ATP MalK | Aes | MalY α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→4)-D-glucose;amylotriose | α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→4)-D-glucose;amylotriose | | adenosine-5'-triphosphate;adenosine-triphosphate;adenylpyrophosphate LuxR/UhpA Local Regulator Using internal synthesized signals [EXP-IDA-PURIFIED-PROTEIN|W] - Weak 2524384, 2538630, 2664421, 3015733, 7830577 ECK120011412 MarA CfxB,DNA-binding transcriptional dual regulator MarA,InaR,NfxC,NorB,SoxQ marA MarA CfxB;InaR;NfxC;NorB;SoxQ asymmetric AraC/XylS Local Regulator [EXP|W] - Weak 27105118, 31251753, 31438868, 8383113, 8491710, 8522515 ECK120013191 MarR CfxB,DNA-binding transcriptional repressor MarR,InaR,SoxQ marR MarR MarR-2,4-dinitrophenol | MarR-Benzoate | MarR-Menadione | MarR-Paraquat | MarR-Phenazine methosulfate | MarR-Plumbagin | MarR-Sodium salicylate | MarR-salicylate B1530;CfxB;InaR;MarR;SoxQ 2,4-dinitrophenol | Benzoate | Sodium salicylate | salicylate | Paraquat | Plumbagin | Phenazine methosulfate | Menadione α-dinitrophenol;1-hydroxy-2,4-dinitrobenzene;2,4-DNP | | | 2-HBA;2-hydroxybenzoate;2-hydroxybenzoic acid;SA;o-hydroxybenzoate;o-hydroxybenzoic acid;salicylic acid | | | | MarR Local Regulator [EXP-IDA-PURIFIED-PROTEIN|W] - Weak 11751765, 7768850, 7777530, 8282690, 8383113, 8521301 ECK125141911 MatA DNA-binding transcriptional dual regulator MatA,EcpR,YkgK matA MatA EcpR;YkgK inverted-repeat LuxR/UhpA Local Regulator [EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 15556475, 22422754 ECK125140737 MazE ChpAI,ChpR,antitoxin of the MazF-MazE toxin-antitoxin system MazE mazE MazE ChpAI;ChpR MazE Local Regulator [EXP|W] - Weak ECK125257200 MazE-MazF MazE-MazF "addiction module",MazE-MazF antitoxin/toxin complex / DNA-binding transcriptional repressor,MazEF,MazFE mazE, mazF MazE-MazF MazE-MazF "addiction module";MazEF;MazFE inverted-repeat Local Regulator [EXP|W] - Weak ECK120051441 McbR DNA-binding transcriptional dual regulator McbR,YncC mcbR McbR YncC inverted-repeat GntR Local Regulator [EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-UNPURIFIED-PROTEIN|W],[EXP-IDA-PART-PURIFIED-PROTEIN-HH|W] - Weak 15556475, 18309357, 20713450 ECK120012347 MelR DNA-binding transcriptional dual regulator MelR melR MelR | MelR-melibiose B4118;MelR melibiose α-D-Galp-(1->6)-D-Glc;6-(α-D-galactosido)-D-glucose;6-O-α-D-galactopyranosyl-D-glucose;6-O-(α-D-galactopyranosyl)-D-glucopyranose;D-Gal-α(1->6)-D-glucose;D-melibiose asymmetric AraC/XylS Local Regulator Sensing external and internal signals [EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W] - Weak 10747919, 10760179, 1445207, 16621812, 18346968, 2684786, 2830169, 8010957 ECK125302602 MetJ DNA-binding transcriptional repressor MetJ metJ MetJ--adenosyl-L-methionine MetJ | MetJ-adenine | MetJ-MTA MetJ-S-adenosylmethionine;MetJ-SAM S-adenosyl-L-methionine adenine | S-methyl-5'-thioadenosine (S)-S-adenosyl-L-methionine;2-S-adenosyl-L-methionine;S-adenosyl-methionine;S-adenosylmethionine;AdoMet;SAM;adenosylmethionine asymmetric, inverted-repeat MetJ Local Regulator Using internal synthesized signals [COMP-HINF-FN-FROM-SEQ|W],[EXP-IPI|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 11448880, 22890386, 2543976, 2994061, 6094549 ECK120012802 MetR DNA-binding transcriptional dual regulator MetR metR MetR | MetR-L-homocysteine L-homocysteine homo-cys;homocysteine LysR Local Regulator Using internal synthesized signals [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 1379743, 2205852, 2543976, 2643109, 2656646, 7608086, 8257110, 8757744 ECK120011482 MhpR DNA-binding transcriptional activator MhpR mhpR MhpR-3-(2,3-dihydroxyphenyl)propionate [DHPP] | MhpR-3-(3-hydroxyphenyl)propanoate MhpR B0346;MhpR;MhpR-3HPP 3-(2,3-dihydroxyphenyl)propionate [DHPP] | 3-(3-hydroxyphenyl)propanoate 3-(3-hydroxyphenyl)propanoic acid;3-(3-hydroxyphenyl)propionate;3-(3-hydroxyphenyl)propionic acid;3HPP;MHP;dihydro-3-coumarate;m-hydroxyphenylpropionate;m-hydroxyphenylpropionic acid IclR Local Regulator Sensing external and internal signals [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W] - Weak 12748194, 9098055 ECK120011240 Mlc DNA-binding transcriptional repressor Mlc,DgsA mlc Mlc Mlc-EIIGlC DgsA EIIGlc inverted-repeat ROK Local Regulator [EXP-IDA-BINDING-OF-CELLULAR-EXTRACTS|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 10464268, 10469172, 11032803, 11157755, 9484892, 9484893, 9767573 ECK125134665 MlrA DNA-binding transcriptional activator MlrA,YehV mlrA MlrA YehV inverted-repeat MerR Local Regulator [COMP-HINF|W],[EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 11489123, 12775697, 15556475, 20874755 ECK120011949 MngR DNA-binding transcriptional repressor MngR,FarR,YbgB mngR MngR FarR GntR Local Regulator Using internal synthesized signals [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 12757941, 14645248, 2548486, 7805834 ECK125302600 MntR DNA-binding transcriptional dual regulator MntR,YbiQ mntR MntR-Mn MntR | Mn2+ | Cd2+ Mn(II) (incorrect);Mn++;MnII;manganese(II) | inverted-repeat Local Regulator [COMP-HINF|W],[COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IPI|W] - Weak 11466284, 21908668 ECK120011220 ModE ChlD,DNA-binding transcriptional dual regulator ModE,ModE-MoO42-,ModR modE ModE-molybdate ModE ModE;ModE-MoO42- molybdate MoO4-2;MoO42-;molybdate ion LysR Local Regulator External sensing using transported metabolites [COMP-HINF-FN-FROM-SEQ|W],[EXP-IDA-UNPURIFIED-PROTEIN-NH|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 13129959, 14641908, 9044285, 9466267, 9721306 ECK120011593 MprA DNA-binding transcriptional regulator MprA,EmrR mprA MprA MprA-salicylate | MprA-Carbonyl cyanide p-(trifluoro-methoxy)phenylhydrazone | MprA-2,4-dinitrophenol | MprA-carbonylcyanide m-chlorophenylhydrazone MprA-CCCP Carbonyl cyanide p-(trifluoro-methoxy)phenylhydrazone | salicylate | carbonylcyanide m-chlorophenylhydrazone | 2,4-dinitrophenol 2-HBA;2-hydroxybenzoate;2-hydroxybenzoic acid;SA;o-hydroxybenzoate;o-hydroxybenzoic acid;salicylic acid | (3-chlorophenyl)hydrazonomalononitrile;CCCP;Carbonylcyanide-3-chlorophenylhydrazone | α-dinitrophenol;1-hydroxy-2,4-dinitrobenzene;2,4-DNP inverted-repeat MarR Local Regulator [EXP-IDA|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 10438794, 10991887, 30578262, 33077659 ECK120051460 MqsA YgiT,antitoxin of the MqsRA toxin-antitoxin system / DNA-binding transcriptional repressor MqsA mqsA MqsA YgiT inverted-repeat CxxCG_CxxCG_HTH, MqsR Local Regulator [COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-PART-PURIFIED-PROTEIN-NH|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 15556475, 19690171, 20105222 ECK125165914 MraZ DNA-binding transcriptional repressor MraZ,YabB mraZ MraZ YabB inverted-repeat Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IPI|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 24659771 ECK120048826 MurR DNA-binding transcriptional dual regulator MurR,YfeT murR MurR MurR--acetyl-D-muramate 6-phosphate MurR-MurNAc-6-P N-acetyl-D-muramate 6-phosphate MurNAc-6-P RpiR Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 18723630 ECK120011265 Nac DNA-binding transcriptional dual regulator Nac nac Nac inverted-repeat LysR Local Regulator [EXP-IGI-FUNC-COMPLEMENTATION|S],[EXP-IDA|W],[COMP-HINF-FN-FROM-SEQ|W] - Strong 11121068, 9495755 ECK120013202 NadR DNA-binding transcriptional repressor/NMN adenylyltransferase NadR,NadI nadR NadR inverted-repeat HTH_3 Local Regulator [COMP-AINF-FN-FROM-SEQ|W],[EXP-IMP|W] - Weak 12446641, 4349027 ECK120011908 NagC DNA-binding transcriptional dual regulator NagC,NagR,transcriptional repressor of nag (N-acetylglucosamine) operon nagC NagC NagC--acetyl-D-glucosamine 6-phosphate NagR;transcriptional repressor of nag (N-acetylglucosamine) operon B0676;NagC;NagC-NAcGlc-6-P;NagR N-acetyl-D-glucosamine 6-phosphate N-acetyl-D-glucosamine-6-P;N-acetyl-glucosamine 6-phosphate;N-acetyl-glucosamine-6-P;N-acetylglucosamine-6-P;GlcNAc-6-P inverted-repeat MarR Local Regulator External sensing using transported metabolites [EXP-IDA-PURIFIED-PROTEIN|W] - Weak 11139621, 15066032, 15534208, 15743943, 17238917, 1766379, 1848637, 2190615, 2668691, 7545108 ECK120012559 NanR YhcK nanR NanR NanR--acetylneuraminate B3226;NanR;NanR-NANA;YhcK N-acetylneuraminate 5-acetamido-3,5-dideoxy-D-galacto-non-2-ulopyranosonate;5-acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid;5-acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid;N-acetylneuraminic acid;NANA;Neu5Ac;O-sialic acid;sialate;sialic acid asymmetric GntR Local Regulator External sensing using transported metabolites [EXP-IGI-FUNC-COMPLEMENTATION|S],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IPI|W] - Strong 12897000, 33790291 ECK120011502 NarL DNA-binding transcriptional dual regulator NarL,FrdR,NarR,nitrate/nitrite response regulator NarL narL NarL-phosphorylated NarL FrdR;NarL;NarL response regulator - phosphorylated;NarL-Pasp59;NarR Phosphate LuxR/UhpA Local Regulator External-Two-component systems [COMP-HINF-FN-FROM-SEQ|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IMP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 1482126, 15995204, 2066339, 2157156, 2648330, 2649492, 2657652, 7601827, 7643383, 7699720, 7854119, 8057356, 8098993, 8501030 ECK120011508 NarP DNA-binding transcriptional dual regulator NarP,nitrate/nitrite response regulator NarP narP NarP-phosphorylated NarP NarP;NarP response regulator - phosphorylated;NarP-Pasp59 Phosphate inverted-repeat LuxR/UhpA Local Regulator External-Two-component systems [COMP-HINF-FN-FROM-SEQ|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IMP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 1482126, 15978080, 2157156, 7699720, 8098993, 8501030, 9302020 ECK120035042 NemR DNA-binding transcriptional repressor NemR,YdhM nemR NemR NemR-methylglyoxal YdhM methylglyoxal 2-oxopropanal;acetylformaldehyde;pyruvaldehyde;pyruvic aldehyde inverted-repeat TetR/AcrR Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 15556475, 18567656 ECK125134855 NfeR DNA-binding transcriptional repressor NfeR,YqjI nfeR NfeR NfeR-Fe YqjI NfeR-nickel;YqjI-nickel Ni2+ Ni++;NiII;nickel(II) inverted-repeat PadR Local Regulator - - ECK120011378 NhaR AntO,DNA-binding transcriptional activator NhaR,YaaB nhaR NhaR-Na NhaR AntO;B0020;NhaR;YaaB Na+ NaI;sodium(I) LysR Local Regulator External sensing using transported metabolites [COMP-HINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W] - Weak 11577158, 12867437, 1316901, 1630901, 16997959, 2429258, 3413113, 8168494, 9312050 ECK125302598 NikR DNA-binding transcriptional repressor NikR,YhhG nikR NikR-Cd | NikR NikR;NikR-Ni | | | | B3481;YhhG Cd2+ | Co2+ | Cu+ | Zn2+ | Ni2+ Co++;CoII;cobalt(II) | CuI;copper(I);cuprous copper;cuprous ion | Zn(II) (incorrect);ZnII;zinc(II) | Ni++;NiII;nickel(II) inverted-repeat CopG Local Regulator [EXP-IDA-PURIFIED-PROTEIN|W] - Weak 10787413 ECK125228822 NimR DNA-binding transcriptional repressor NimR,YeaM nimR NimR YeaM inverted-repeat AraC/XylS Local Regulator [EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 15556475, 25790494 ECK120011938 NorR DNA-binding transcriptional dual regulator NorR,YgaA norR NorR YgaA inverted-repeat EBP Local Regulator [EXP-IDA|W],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W] - Weak 11751865, 12142437, 12529359, 14718666, 15375149, 16193057, 7894055 ECK120033053 NrdR NrdR transcriptional repressor,YbaD nrdR NrdR-dATP | NrdR-ATP | NrdR-Zn NrdR dATP | ATP | Zn2+ adenosine-5'-triphosphate;adenosine-triphosphate;adenylpyrophosphate | Zn(II) (incorrect);ZnII;zinc(II) NrdR Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IMP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 17496099 ECK120016814 NsrR DNA-binding transcriptional regulator NsrR,YjeB nsrR NsrR | NsrR-[2Fe-2S]reduced NsrR-[2Fe-2S] oxidized | NsrR-nitric oxide [2Fe-2S] reduced [2Fe-2S]2+ oxidized | nitric oxide NO;nitrogen monoxide;nitrogen protoxide inverted-repeat Rrf2 Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IPI|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 16428390, 17720788, 18433631, 19656291, 20533909 ECK125257192 NtrC DNA-binding transcriptional dual regulator NtrC,GlnG,GlnT,NtrC response regulator glnG NtrC-phosphorylated NRI;NtrC response regulator - phosphorylated;NtrC-Pasp54;NtrC-Pasp Phosphate inverted-repeat Local Regulator External-Two-component systems [COMP-HINF-FN-FROM-SEQ|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 10960104, 12730324, 2882477, 3304660, 41243, 6148334 ECK125257196 OmpR Cry,DNA-binding transcriptional dual regulator OmpR,Kmt,OmpB,OmpR response regulator ompR OmpR-phosphorylated | OmpR OmpR response regulator - phosphorylated;OmpR-P;OmpR-Pasp55 | Phosphate direct-repeat Local Regulator External-Two-component systems [COMP-HINF-FN-FROM-SEQ|W],[EXP-IMP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 1482126, 16855227, 2157156, 26209678, 27050393, 2997120, 3010044, 3020561, 3023382, 6263866, 6292199, 7699720, 8098993 ECK120011302 OxyR DNA-binding transcriptional dual regulator OxyR,MomR,Mor,bifunctional regulatory protein sensor for oxidative stress oxyR OxyR MomR;Mor;bifunctional regulatory protein sensor for oxidative stress inverted-repeat LysR Local Regulator Using internal synthesized signals [IDA-PURIFIED-PROTEIN-NH|S] - Strong 1864839, 2167922, 22539721, 2471187, 2511419, 2551682, 8265357, 8483417 ECK120011563 PaaX DNA-binding transcriptional repressor PaaX,YdbY paaX PaaX PaaX-phenylacetyl-CoA phenylacetyl-CoA phenylacetate-CoA inverted-repeat PaaX Local Regulator Using internal synthesized signals [EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W] - Weak 10766858, 11243806 ECK125242743 PdeL DNA-binding transcriptional regulator/c-di-GMP phosphodiesterase PdeL,YahA pdeL PdeL LuxR/UhpA Local Regulator [COMP-HINF|W],[EXP-IEP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 26553851 ECK120012246 PdhR AceC,DNA-binding transcriptional dual regulator PdhR,GenA,YacB pdhR PdhR PdhR-pyruvate AceC;GenA;YacB B0113;GenA;PdhR;YacB pyruvate α-ketopropionic acid;2-oxo-propionic acid;2-oxopropanoate;2-oxopropanoic acid;BTS;acetylformic acid;alpha-ketopropionic acid;pyroracemic acid;pyruvic acid inverted-repeat GntR Local Regulator Using internal synthesized signals [COMP-HINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W],[EXP-IDA-PART-PURIFIED-PROTEIN|W] - Weak 17513468, 2060763, 7783622, 8057842, 8262214 ECK120020634 PepA CarP,PepA,XerB pepA PepA CarP;XerB inverted-repeat Aminopeptidase Local Regulator [EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W] - Weak 14741201, 15049810, 2670557 ECK125158270 PgrR DNA-binding transcriptional repressor PgrR,YcjZ pgrR PgrR YcjZ inverted-repeat LysR Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IDA-PART-PURIFIED-PROTEIN-NH|W] - Weak 10734204, 15556475, 23301696 ECK120011306 PhoB DNA-binding transcriptional dual regulator PhoB,PhoB response regulator,PhoT phoB PhoB-phosphorylated PhoB PhoB response regulator - phosphorylated;PhoB-Pasp53;PhoT Phosphate direct-repeat OmpR Local Regulator External-Two-component systems [COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 10986267, 1482126, 2157156, 3054125, 324866, 3537313, 6310121, 6343798, 7009567, 7699720, 7855419, 8098993 ECK120011492 PhoP DNA-binding transcriptional dual regulator PhoP,PhoP response regulator phoP PhoP-phosphorylated PhoP PhoP;PhoP response regulator - phosphorylated;PhoP-Pasp51 Phosphate direct-repeat OmpR Local Regulator External-Two-component systems [COMP-HINF-FN-FROM-SEQ|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IMP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 10464230, 12813061, 1482126, 1530848, 15703297, 1729240, 2157156, 7699720, 8098993 ECK120014044 PlaR DNA-binding transcriptional repressor PlaR,YiaJ plaR PlaR YiaJ inverted-repeat IclR Local Regulator [EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W],[EXP-IPI|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 10913096, 30137486, 9525947 ECK120015234 PrpR DNA-binding transcriptional dual regulator PrpR,YahP prpR PrpR-(2)-2-methylcitrate PrpR B0330;PrpR;PrpR-2-methylcitrate;YahP (2S,3S)-2-methylcitrate (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate EBP Local Regulator [EXP-IDA|W],[EXP-IEP|W] - Weak 15805526, 27718375 ECK120011400 PspF DNA-binding transcriptional dual regulator PspF,YcjB pspF PspF | PspF YcjB | inverted-repeat EBP Local Regulator [COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 15485810, 8606168, 9260970, 9302010, 9878422 ECK125328144 PunR DNA-binding transcriptional activator PunR,YdhB,putative LysR family DNA-binding transcriptional regulator YdhB punR PunR YdhB;putative LysR family DNA-binding transcriptional regulator YdhB inverted-repeat Local Regulator [COMP-HINF|W],[COMP-AINF-FN-FROM-SEQ|W] - Weak 11566977, 15556475, 34413462, 9022701 ECK120012854 PurR DNA-binding transcriptional repressor PurR purR PurR-Guanine | PurR-hypoxanthine PurR Guanine | hypoxanthine GalR/LacI Local Regulator Using internal synthesized signals [COMP-HINF-FN-FROM-SEQ|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 12598694, 1729205, 1971620, 2211510, 2404765, 2539360, 3058704, 8106311 ECK120012029 PutA PoaA,PutC,fused DNA-binding transcriptional repressor / proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase PutA,proline utilization A putA PutA PoaA;PutC;proline utilization A asymmetric PutA Local Regulator External sensing using transported metabolites [IDA-PURIFIED-PROTEIN-NH|S] - Strong 11294639, 18586269 ECK125160661 PuuR DNA-binding transcriptional repressor PuuR,YcjC puuR PuuR PuuR-putrescine YcjC putrescine 1,4-butanediamine;1,4-diaminobutane;diaminobutane;tetramethylenediamine inverted-repeat HTH_3 Local Regulator [COMP-AINF-FN-FROM-SEQ|W],[EXP-IMP|W] - Weak 15556475, 15590624 ECK125158264 PyrR DNA-binding transcriptional activator PyrR,YpdB pyrR PyrR-pyruvate | PyrR-phosphorylated PyrR PyrR-BTS | PyrR-Pasp pyruvate α-ketopropionic acid;2-oxo-propionic acid;2-oxopropanoate;2-oxopropanoic acid;BTS;acetylformic acid;alpha-ketopropionic acid;pyroracemic acid;pyruvic acid Local Regulator External-Two-component systems [COMP-HINF|W],[EXP-IEP|W],[EXP-IDA-PART-PURIFIED-PROTEIN-NH|W],[EXP-IPI|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 11361063, 23222720, 30624637 ECK120012277 QseB DNA-binding transcriptional activator QseB,QseB response regulator,YgiX qseB QseB-Phosphorylated QseB QseB;QseB response regulator - phosphorylated;QseB-Pasp51;YgiX Phosphate inverted-repeat OmpR Local Regulator External-Two-component systems [EXP|W],[EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IPI|W] - Weak 11929534, 16194231, 32979869 ECK125257199 RacR Rac prophage; DNA-binding transcriptional repressor RacR,RarC,YdaR racR RacR RarC;YdaR inverted-repeat Local Regulator [COMP-HINF|W],[EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 10734204, 15556475, 29205228, 29205229 ECK120013229 RbsR DNA-binding transcriptional dual regulator RbsR,regulator for rbs operon rbsR RbsR RbsR-D-ribose regulator for rbs operon B3753;RbsR D-ribose ribose inverted-repeat GalR/LacI Local Regulator External sensing using transported metabolites [EXP|W] - Weak 1304370, 7686882 ECK125158217 RcdA YbjK rcdA RcdA RcdA-trimethylamine -oxide | RcdA-tris RcdA-TMAO | trimethylamine N-oxide | tris TMAO | tris hydrochloride;tris(hydroxymethyl)amino methane inverted-repeat TetR/AcrR Local Regulator [EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IPI|W],[EXP-IMP|W] - Weak 15556475, 23233451, 34288132 ECK125162247 RclR DNA-binding transcriptional activator RclR,YkgD rclR RclR YkgD inverted-repeat AraC/XylS Local Regulator [COMP-HINF-FN-FROM-SEQ|W] - Weak 10734204, 15556475 ECK120033010 RcnR DNA-binding transcriptional repressor RcnR,YohL rcnR RcnR RcnR-Ni YohL RcnR-nickel | Co2+ | Ni2+ Co++;CoII;cobalt(II) | Ni++;NiII;nickel(II) inverted-repeat RcnR_FrmR_like_DUF156 Local Regulator [EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 16956381, 17120142, 19703465 ECK125257195 RcsAB RcsAB DNA-binding transcriptional dual regulator rcsA, rcsB RcsAB inverted-repeat Local Regulator [EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W],[EXP-IGI|W] - Weak 10702265, 12864862, 16000739, 1943696, 1999391, 2404948, 8576059, 9882673 ECK120011324 RcsB DNA-binding transcriptional activator RcsB,RcsB response regulator rcsB RcsB-phosphorylated RcsB | RcsB-acetylated Pasp56 RcsB;RcsB;RcsB response regulator - phosphorylated;RcsB-Pasp56 Phosphate acetyl LuxR/UhpA Local Regulator External-Two-component systems [EXP|W],[EXP-IDA|W],[EXP-IGI-FUNC-COMPLEMENTATION|S],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W],[EXP-IPI|W],[IDA-PURIFIED-PROTEIN-NH|S],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W],[EXP-IGI|W] - Strong 10702265, 12864862, 1482126, 16000739, 1943696, 1999391, 20189963, 20952573, 2157156, 23852870, 2404948, 32094588, 7699720, 8098993, 8576059, 9882673 ECK125257193 RcsB-BglJ RcsB-BglJ DNA-binding transcriptional activator,RcsBgl bglJ, rcsB RcsB-BglJ RcsBgl asymmetric Local Regulator [EXP-IGI-FUNC-COMPLEMENTATION|S],[EXP-IEP|W],[EXP-IMP|W],[EXP-IPI|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 20952573 ECK120048934 RelB Qin prophage, antitoxin RelB,Qin prophage, antitoxin of the RelE-RelB toxin-antitoxin system and DNA binding transcriptional repressor RelB,Qin prophage; antitoxin/DNA-binding transcriptional repressor RelB relB RelB inverted-repeat RelB, RelE Local Regulator [COMP-AINF|W],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 10501926, 18501926 ECK125257202 RelB-RelE RelB-RelE antitoxin/toxin complex / DNA-binding transcriptional repressor,RelBE relB, relE RelB-RelE RelBE inverted-repeat Local Regulator [COMP-AINF|W],[EXP-IEP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 18501926 ECK120012877 RhaR DNA-binding transcriptional activator RhaR rhaR RhaR-L-rhamnose | RhaR-α-L-rhamnopyranose RhaR B3906;RhaR;RhaR-rhamnose | α-L-rhamnopyranose | L-rhamnose 6-deoxy-L-mannose;L-mannomethylose AraC/XylS Local Regulator External sensing using transported metabolites [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 10464186, 1339463, 1551902, 17513476, 3316663, 8230210, 8346018 ECK120012337 RhaS DNA-binding transcriptional activator RhaS rhaS RhaS-α-L-rhamnopyranose | RhaS | RhaS-L-rhamnose RhaS-rhamnose α-L-rhamnopyranose | L-rhamnose 6-deoxy-L-mannose;L-mannomethylose asymmetric AraC/XylS Local Regulator External sensing using transported metabolites [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W],[EXP-IPI|W] - Weak 10464186, 10940041, 15342598, 17513476, 18366439, 3316663, 8230210, 8346018 ECK120011190 Rob CbpB,DNA-binding transcriptional dual regulator Rob,RobA,right origin-binding protein rob Rob CbpB;RobA;right origin-binding protein asymmetric AraC/XylS Local Regulator [EXP|W] - Weak 7896685, 8449900 ECK125336166 RpoN σ54,GlnF,NtrA,RNA polymerase sigma factor RpoN,RNA polymerase, sigma 54 (sigma N) factor,sigma 54 factor,sigma N,sigma N factor rpoN RpoN σ54;GlnF;NtrA;RNA polymerase, sigma 54 (sigma N) factor;sigma 54 factor;sigma N;sigma N factor Local Regulator [EXP|W] - Weak 26425847 ECK125158221 RspR DNA-binding transcriptional repressor RspR,YdfH rspR RspR YdfH inverted-repeat GntR Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 10734204, 15556475, 22972332 ECK120033066 RstA DNA-binding transcriptional regulator RstA,RstA response regulator,UrpT rstA RstA-phosphorylated RstA RstA response regulator - phosphorylated;RstA-Pasp52;UrpT Phosphate OmpR Local Regulator External-Two-component systems [EXP-IMP|W] - Weak 12618449, 12813061 ECK120011489 RtcR DNA-binding transcriptional activator RtcR,YhgB rtcR RtcR YhgB inverted-repeat EBP Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 9738023 ECK120033905 RutR DNA-binding transcriptional dual regulator RutR,YcdC rutR RutR RutR-thymine | RutR-uracil YcdC thymine | uracil 5-methyl-2,4(1H,3H)-pyrimidinedione;5-methyluracil;T | 2,4-(1H,3H)-pyrimidinedione;U inverted-repeat TetR/AcrR Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-PART-PURIFIED-PROTEIN-NH|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W] - Weak 15556475, 16540542, 17919280, 20472642 ECK120011856 SdiA DNA-binding transcriptional dual regulator SdiA sdiA SdiA inverted-repeat LuxR/UhpA Local Regulator External sensing using transported metabolites [EXP|W] - Weak ECK120032161 SgrR DNA-binding transcriptional dual regulator SgrR,YabN sgrR SgrR YabN inverted-repeat MarR Local Regulator [EXP-IMP|W] - Weak 15522088 ECK120012253 SlyA DNA-binding transcriptional dual regulator SlyA slyA SlyA inverted-repeat MarR Local Regulator [EXP|W] - Weak 10027972, 12057949, 14996792, 32849447 ECK120013242 SoxR DNA-binding transcriptional dual regulator SoxR,MarC soxR SoxR-[2Fe-2S] oxydized | SoxR SoxR-[2Fe-2S] reduced MarC [2Fe-2S]3+ oxydized [2Fe-2S]2+ reduced inverted-repeat MerR Local Regulator Using internal synthesized signals [IDA-PURIFIED-PROTEIN-NH|S] - Strong 11470373, 1400156, 1653416, 1708380, 7673113 ECK120011298 SoxS DNA-binding transcriptional dual regulator SoxS,regulation of superoxide response regulon soxS SoxS regulation of superoxide response regulon asymmetric AraC/XylS Local Regulator [EXP|W] - Weak 1653416, 1708380, 7891555, 7896696, 8034583, 8226698, 8265357 ECK120013144 SrlR DNA-binding transcriptional repressor SrlR,GutR srlR SrlR SrlR-D-sorbitol GutR B2707;GutR;GutR-D-sorbitol;GutR-sorbitol;SrlR D-sorbitol (2S,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol;D-glucitol;L-gulitol;iso-sorbide inverted-repeat DeoR Local Regulator External sensing using transported metabolites [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W] - Weak 3062173, 31608580 ECK120034571 StpA DNA-binding transcriptional repressor StpA with RNA chaperone activity,H-NS-like DNA-binding transcriptional repressor with RNA chaperone activity,HnsB stpA StpA H-NS-like DNA-binding transcriptional repressor with RNA chaperone activity;HnsB inverted-repeat HNS Local Regulator [EXP|W] - Weak ECK125202685 SutR DNA-binding transcriptional dual regulator SutR,YdcN sutR SutR YdcN inverted-repeat HTH_3 Local Regulator [EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 10734204, 15556475, 24391520, 25406449 ECK120013255 TdcA DNA-binding transcriptional activator TdcA,transcriptional activator of tdc operon tdcA TdcA transcriptional activator of tdc operon inverted-repeat LysR Local Regulator Sensing external and internal signals [EXP|W] - Weak 2660107, 3003533, 7928991, 8413189, 8413267 ECK120013259 TdcR DNA-binding transcriptional activator TdcR,threonine dehydratase operon activator protein tdcR TdcR threonine dehydratase operon activator protein inverted-repeat TdcR Local Regulator Sensing external and internal signals [EXP|W] - Weak 2573820, 2660107, 7928991 ECK120012482 TorR DNA-binding transcriptional dual regulator TorR,TorR response regulator torR TorR | TorR-phosphorylated TorR-TorI TorR;TorR response regulator - phosphorylated;TorR-Pasp53;TorR-Pasp Phosphate TorI OmpR Local Regulator External-Two-component systems [EXP|W],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 12657056, 1482126, 2157156, 7699720, 8083154, 8098993, 8596446 ECK120011406 TreR DNA-binding transcriptional repressor TreR treR TreR TreR-α,α-trehalose 6-phosphate | TreR-Trehalose | TreR-D-trehalose 6-phosphate TreR-trehalose 6-phosphate D-trehalose 6-phosphate | Trehalose trehalose 6-phosphate;trehalose phosphate | inverted-repeat GalR/LacI Local Regulator Sensing external and internal signals [EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 7608078, 9148912 ECK120012176 TrpR DNA-binding transcriptional repressor TrpR,RtrY trpR TrpR-L-tryptophan TrpR TrpR-trp;TrpR-tryptophan L-tryptophan 2-amino-3-indolylpropanic acid;L-trp;W;trofan;trp;tryptacin;tryptophan TrpR Local Regulator Sensing external and internal signals [COMP-HINF-FN-FROM-SEQ|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 1740124, 1935980, 2182120, 2207078, 3290685, 3315853, 3600756, 7001368, 7012834, 8176748, 8613990 ECK120011194 TyrR DNA-binding transcriptional dual regulator TyrR tyrR TyrR-L-phenylalanine | TyrR | TyrR-L-tryptophan | TyrR-L-tyrosine B1323;TyrR;TyrR-Phenylalanine;TyrR-phe | | | B1323;TyrR;TyrR-Tyrosine;TyrR-tyr;TyrR-tyrosine L-tyrosine | L-tryptophan | L-phenylalanine L-tyr;Y;tyr;tyrosine | 2-amino-3-indolylpropanic acid;L-trp;W;trofan;trp;tryptacin;tryptophan | 2S-α-phenylalanine;F;L-phe;endophenyl;phe;phenylalanine inverted-repeat EBP Local Regulator Sensing external and internal signals [EXP-IMP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 15049824, 1943694, 1970563, 3001057, 4887504, 7961453, 8106498, 8444880, 8449883 ECK125286592 UhpA DNA-binding transcriptional activator UhpA,UhpA response regulator uhpA UhpA-phosphorylated UhpA UhpA response regulator - phosphorylated;UhpA-Pasp54;UhpA-Pasp Phosphate inverted-repeat LuxR/UhpA Local Regulator External-Two-component systems [EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W],[EXP-IPI|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 10512697, 10966457, 11976297, 1482126, 1569007, 1569008, 2157156, 3301805, 7596290, 7686882, 7699720, 8098993, 8999880, 9220010 ECK120012153 UidR DNA-binding transcriptional repressor UidR,GusR uidR UidR GusR inverted-repeat TetR/AcrR Local Regulator External sensing using transported metabolites [EXP-IEP|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 2823062, 3079718, 3934044, 6276362, 776933, 776934 ECK120012165 UlaR DNA-binding transcriptional repressor UlaR,YjfQ ulaR UlaR UlaR-L-ascorbate 6-phosphate YjfQ B4191;UlaR;UlaR-L-ascorbate-6P;YjfQ L-ascorbate 6-phosphate inverted-repeat DeoR Local Regulator [EXP-IEP|W],[EXP-IPI|W] - Weak 12374842, 18844374 ECK125228870 UvrY DNA-binding transcriptional activator UvrY,UvrY response regulator,YecB uvrY UvrY-phosphorylated UvrY UvrY;UvrY response regulator - phosphorylated;UvrY-Pasp54;YecB Phosphate LuxR/UhpA Local Regulator External-Two-component systems [EXP-IGI-FUNC-COMPLEMENTATION|S],[EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Strong 11022030, 12193630, 12533459 ECK120012145 UxuR DNA-binding transcriptional repressor UxuR uxuR UxuR UxuR-D-fructuronate | UxuR-α-D-glucuronate-α-D-galacturonate B4324;UxuR | α-D-galacturonate | D-fructuronate | α-D-glucuronate α-D-galacturonic acid | | α-D-glucopyranuronic acid;α-D-glucuronic acid inverted-repeat GntR Local Regulator [EXP-IEP|W] - Weak 2823062, 3079718, 3083215 ECK120013780 XapR DNA-binding transcriptional activator XapR,PndR,YfeB xapR XapR-xanthosine XapR xanthosine 9 β-D-ribofuranosylxanthine;xanthine riboside LysR Local Regulator External sensing using transported metabolites [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W] - Weak 2201776, 7559336 ECK120013786 XylR DNA-binding transcriptional dual regulator XylR xylR XylR-α-D-xylopyranose XylR B3569;XylR;XylR-xylose α-D-xylopyranose α-D-xylose;D-xylose;wood sugar;xylose AraC/XylS Local Regulator External sensing using transported metabolites [EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W] - Weak 26527647, 9371449 ECK125257198 XynR CP4-6 prophage; DNA-binding transcriptional repressor XynR,YagI xynR XynR-D-xylonate XynR D-xylonate Local Regulator [COMP-AINF|W],[COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 15556475, 29087459 ECK125336164 YciT DNA-binding transcriptional dual regulator YciT,DeoT yciT YciT DeoT inverted-repeat Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IMP|W] - Weak 10734204, 15556475, 16451192 ECK125286589 YcjW DNA-binding transcriptional repressor YcjW,putative LacI-type DNA-binding transcriptional regulator YcjW ycjW YcjW putative LacI-type DNA-binding transcriptional regulator YcjW inverted-repeat GalR/LacI Local Regulator [EXP-IDA|W],[COMP-HINF-FN-FROM-SEQ|W],[EXP-IMP|W] - Weak 10734204, 15556475, 24391520, 31253770 ECK125300414 YdcI DNA-binding transcriptional dual regulator YdcI ydcI YdcI inverted-repeat Local Regulator [EXP-IDA-PURIFIED-PROTEIN-HH|S],[COMP-HINF-FN-FROM-SEQ|W],[EXP-IPI|W] - Strong 10734204, 15556475, 24962596, 30137486 ECK120012313 YdeO DNA-binding transcriptional dual regulator YdeO ydeO YdeO inverted-repeat AraC/XylS Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[EXP-IDA-PURIFIED-PROTEIN|W],[EXP-IMP|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 12399493, 12694615, 15489450, 20603130, 25375160, 9409145 ECK125228840 YebK DNA-binding transcriptional repressor YebK yebK YebK YebK-2-dehydro-3-deoxy-D-gluconate 6-phosphate 2-dehydro-3-deoxy-D-gluconate 6-phosphate 2-dehydro-3-deoxy-6-phospho-D-gluconate;2-keto-3-deoxy-6-P-gluconate;2-keto-3-deoxy-6-phospho-D-gluconate;2-keto-3-deoxy-6-phospho-gluconate;2-keto-3-deoxy-6-phosphogluconate;2-keto-3-deoxygluconate-6-P;3-deoxy-D-erythro-hex-2-ulosonate-6-phosphate;3-deoxy-D-erythro-hex-2-ulosonic acid 6-phosphate;6-p-2-k-3-deo-gluconate;6-phospho-2-dehydro-3-deoxy-D-gluconate;6-phospho-2-dehydro-3-deoxygluconate;6-phospho-2-keto-3-deoxygluconate;KDGP;KDPG inverted-repeat RpiR Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[COMP-AINF-FN-FROM-SEQ|W],[IDA-PURIFIED-PROTEIN-NH|S],[COMP-AINF-SEQ-ORTHOLOGY|W] - Strong 10734204, 15556475, 21849503, 26121029 ECK125135147 YefM YefM antitoxin of the YoeB-YefM toxin-antitoxin pair and DNA binding transcriptional repressor yefM YefM inverted-repeat YefM, YoeB/Txe_like Local Regulator [EXP-IDA-PURIFIED-PROTEIN|W] - Weak 17170003 ECK125257203 YefM-YoeB YefM-YoeB antitoxin/toxin complex / DNA-binding transcriptional repressor,YefMB yefM, yoeB YefM-YoeB YefMB inverted-repeat Local Regulator [EXP-IDA-PURIFIED-PROTEIN|W] - Weak 17170003 ECK120013665 YeiL DNA-binding transcriptional activator YeiL yeiL YeiL inverted-repeat Cyclic nucleotide_binding domain Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Weak 11101674, 9278503 ECK125336162 YfeC DNA-binding transcriptional dual regulator YfeC yfeC YfeC inverted-repeat Local Regulator [COMP-AINF-FN-FROM-SEQ|W] - Weak 15556475 ECK125336165 YgbI DNA-binding transcriptional repressor YgbI ygbI YgbI Local Regulator [COMP-HINF-FN-FROM-SEQ|W] - Weak 10734204, 15556475 ECK120051444 YgiV DNA-binding transcriptional repressor YgiV ygiV YgiV inverted-repeat Local Regulator [EXP-IEP|W],[EXP-IDA-UNPURIFIED-PROTEIN|W] - Weak 18309357 ECK125257182 YhaJ DNA-binding transcriptional activator YhaJ yhaJ YhaJ inverted-repeat Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 10734204, 15556475, 27713734 ECK125336163 YidZ DNA-binding transcriptional dual regulator YidZ,LysR-type transcriptional regulator YidZ yidZ YidZ LysR-type transcriptional regulator YidZ inverted-repeat Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IMP|W] - Weak 10734204, 15546870, 15556475 ECK125228843 YjjQ DNA-binding transcriptional repressor YjjQ yjjQ YjjQ inverted-repeat LuxR/UhpA Local Regulator [EXP-IDA|W],[EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IMP|W] - Weak 15556475, 17846588, 26078445 ECK125110189 YqhC DNA-binding transcriptional activator YqhC yqhC YqhC inverted-repeat AraC/XylS Local Regulator [COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 10734204, 15556475, 20543070 ECK125302599 ZntR DNA-binding transcriptional activator ZntR,YhdM zntR ZntR-Zn | ZntR-Hg ZntR Zn2+ | Cd2+ | Hg Zn(II) (incorrect);ZnII;zinc(II) | | inverted-repeat Local Regulator External sensing using transported metabolites [COMP-HINF-FN-FROM-SEQ|W],[EXP-IDA-BINDING-OF-PURIFIED-PROTEINS|S],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W] - Strong 10048032, 10608803, 10802061, 12445820 ECK120014103 ZraR DNA-binding transcriptional activator ZraR,HydG,ZraR response regulator zraR ZraR-phosphorylated ZraR HydG;ZraR response regulator - phosphorylated;ZraR-Pasp56 Phosphate EBP Local Regulator External-Two-component systems [EXP-IGI-FUNC-COMPLEMENTATION|S],[COMP-HINF-FN-FROM-SEQ|W],[EXP-IEP|W],[COMP|W],[EXP-IEP-GENE-EXPRESSION-ANALYSIS|W],[IDA-PURIFIED-PROTEIN-NH|S] - Strong 11243806, 1482126, 2157156, 30389436, 7699720, 8098993 ECK120012020 Zur DNA-binding transcriptional repressor Zur,YjbK,ZnuR zur Zur-Zn Zur Zn2+ Zn(II) (incorrect);ZnII;zinc(II) Fur Local Regulator [EXP-IEP|W],[COMP-AINF-FN-FROM-SEQ|W],[EXP-IPI|W] - Weak 10816566, 11523983, 11831459, 11931550, 12904577, 9680209